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The map label for this gene is luxQ [H]

Identifier: 53718372

GI number: 53718372

Start: 845513

End: 847321

Strand: Reverse

Name: luxQ [H]

Synonym: BPSL0732

Alternate gene names: 53718372

Gene position: 847321-845513 (Counterclockwise)

Preceding gene: 53718373

Following gene: 53718369

Centisome position: 20.8

GC content: 66.33

Gene sequence:

>1809_bases
ATGAGCCGGGTCGAATGGCGCAATGAAAAAATCATCGTCGCCCTGGGTTCCCTGTGGATCCTGGGCTTCGCCGCGTGGGC
GTTCCTGCTGTACGACCTGCTCGGCACGTCCGTCAAGGAAGGCATTCTGGAAGGCCCGCGCGAAGGCGTGTTCTGGACTG
CCGCGCAATACCGGAACTCGTTCAGCCGGTTCGATCGGCAACTGATTCTCTACGCGGCCGGCGAGAACCGCGACTTCGAC
GCCGTGCTGCTCCAGCTCGACAGCCTCGAAGCGTCGTTCGGCTTTCTCGAGCGGCCGTCCGAAGTCTCCGCGTACTGGCT
GAGCATTCCGAAGGCCCGTGGCGACATCGCCGAGCTGTCGCGCTTCATGGCGAGCCTGCGCCGCGACGTTCCGGCGCTGC
GCGCGCGCCCCGACGATACGAAGCGCGTGCTGGGCGAGCTCGCCCGGCAATGGCCCAAGGTGAACGCGCTCGCGAATTAC
TTTCGCGCGATCGAAATGGAGCAGCGCGATTTCACGTTCCATCAGTTGAAGGAAAAGCGGCGCGCGATCGTCATGCTGGG
CGGCGTGCTCGGCATCATTCTCGGCGCGCTGTTCCTGCTGCTGTTCTACACGGTCCGCACGCGCGGCAGCCTGCTCGAGC
AGCAGCAGGCGGCGCTCGACGCGGAACGCAAGGCGTCCGATCGCGCGTTCGAGATGATCGCCGCGAAAAACGCGTTCCTC
GGCATGGTGAGCCATGAGCTGCGCACGCCGCTGCAGGCGATCTGCGGCTCGATCGAAGTGCTGCTCGCGCGGCCGCAGTC
CGAAGCGAACATGAAGACGATCAAGCGGCTGCAGAACTCGGCCGCGTCGCTCGAAGCGCAGGTGAAGGACCTGACCGACT
ACATCAAGCTGCGGTCCACGAATCGATCGGTGCAGTCGGAGATCGTCGAGGTCGCGCCGCTGCTCGCCGACGTGCTCGAT
CCGTTGCGCGGCCGCATCCGCGACAAGCATCTGAGCACGTCGCTGCGCGTGGAGCCGCCCGCGCTCGTCGTCCGGTCCGA
TCGCAAGCTGATCCAGCAGATCGTGTCGAACCTCGTCGAGAACGCGATCAAATACACGAACAGCGGAACGATCGAGATCT
CGGCCGCGCTCGGCGGCACGCCCGCCAATCGGACCATGACGATCACGGTGCGCGACACCGGCGTCGGCATCGCGCGGCAT
CTGCTCGCGAAGATCTTCGAGCCGTTCTTTCGCGTGAACGATCCGGGCGTGCGGCACGTCGACGGCATCGGCATGGGGCT
CGCGGTCGTCCAGGAGCTCGTCGTCGCGCTGCGCGGGCACGTCGATGTGCGCAGCGCCGTCGGCGAAGGCAGCGAATTCG
CCGTCACGCTGCCCGTCGAGCTGCCCGGCCGCGCCGATGCGCTCGACGACGACGCGCAGCCGTCACCGCGGGCGGCGCAT
CGCGATCTGCGCGCGCTCGTCGTCGACGACAACGAGAACGCGCGCGAAACGCTGGGCGCGATGCTCGCGACGCTCGGCAT
CCGGGTGGATCTGCGCGGCACCGGCAAGGAAGGCTTGCGCTGCTTCGGCGAATGTCAGCACGACATCGTCGTGCTGGATC
TGGAGTTGCCCGACATCAGCGGTTTCGAGGTGGCCGAGCAGATACGCTGGGCGACGTCGTCCGACGCGGCCAGGAAGACG
ACGATACTCGGCGTGAGCGCGTACGAATCGGCGCTGCTCAAGGGCGATCACGCGATCTTCGACGCCTTCATCCCCAAGCC
GATTCATCTGGACACGCTCGGCGGCATCGTGAGCCGGCTGCGAAGCTGA

Upstream 100 bases:

>100_bases
CGCTGTGGATCATGTATCCGCGCGACCAGTTCCCCGATGAGCTGAAGACGCCGATCAGCGAAGCGAAATTCGCGTGGCAG
ATCATCGGGCTCACGGTGAA

Downstream 100 bases:

>100_bases
GCGGCGGGGCCGCGCGCCGCTCGGCTCCGGGCGGCGCGCGCTTCCTTCGCTTCGATGCGGCGCCCTCGACGCACGGGCGA
ATATGCGCCGGGAAGCCCAT

Product: putative two-component regulator histidine sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 602; Mature: 601

Protein sequence:

>602_residues
MSRVEWRNEKIIVALGSLWILGFAAWAFLLYDLLGTSVKEGILEGPREGVFWTAAQYRNSFSRFDRQLILYAAGENRDFD
AVLLQLDSLEASFGFLERPSEVSAYWLSIPKARGDIAELSRFMASLRRDVPALRARPDDTKRVLGELARQWPKVNALANY
FRAIEMEQRDFTFHQLKEKRRAIVMLGGVLGIILGALFLLLFYTVRTRGSLLEQQQAALDAERKASDRAFEMIAAKNAFL
GMVSHELRTPLQAICGSIEVLLARPQSEANMKTIKRLQNSAASLEAQVKDLTDYIKLRSTNRSVQSEIVEVAPLLADVLD
PLRGRIRDKHLSTSLRVEPPALVVRSDRKLIQQIVSNLVENAIKYTNSGTIEISAALGGTPANRTMTITVRDTGVGIARH
LLAKIFEPFFRVNDPGVRHVDGIGMGLAVVQELVVALRGHVDVRSAVGEGSEFAVTLPVELPGRADALDDDAQPSPRAAH
RDLRALVVDDNENARETLGAMLATLGIRVDLRGTGKEGLRCFGECQHDIVVLDLELPDISGFEVAEQIRWATSSDAARKT
TILGVSAYESALLKGDHAIFDAFIPKPIHLDTLGGIVSRLRS

Sequences:

>Translated_602_residues
MSRVEWRNEKIIVALGSLWILGFAAWAFLLYDLLGTSVKEGILEGPREGVFWTAAQYRNSFSRFDRQLILYAAGENRDFD
AVLLQLDSLEASFGFLERPSEVSAYWLSIPKARGDIAELSRFMASLRRDVPALRARPDDTKRVLGELARQWPKVNALANY
FRAIEMEQRDFTFHQLKEKRRAIVMLGGVLGIILGALFLLLFYTVRTRGSLLEQQQAALDAERKASDRAFEMIAAKNAFL
GMVSHELRTPLQAICGSIEVLLARPQSEANMKTIKRLQNSAASLEAQVKDLTDYIKLRSTNRSVQSEIVEVAPLLADVLD
PLRGRIRDKHLSTSLRVEPPALVVRSDRKLIQQIVSNLVENAIKYTNSGTIEISAALGGTPANRTMTITVRDTGVGIARH
LLAKIFEPFFRVNDPGVRHVDGIGMGLAVVQELVVALRGHVDVRSAVGEGSEFAVTLPVELPGRADALDDDAQPSPRAAH
RDLRALVVDDNENARETLGAMLATLGIRVDLRGTGKEGLRCFGECQHDIVVLDLELPDISGFEVAEQIRWATSSDAARKT
TILGVSAYESALLKGDHAIFDAFIPKPIHLDTLGGIVSRLRS
>Mature_601_residues
SRVEWRNEKIIVALGSLWILGFAAWAFLLYDLLGTSVKEGILEGPREGVFWTAAQYRNSFSRFDRQLILYAAGENRDFDA
VLLQLDSLEASFGFLERPSEVSAYWLSIPKARGDIAELSRFMASLRRDVPALRARPDDTKRVLGELARQWPKVNALANYF
RAIEMEQRDFTFHQLKEKRRAIVMLGGVLGIILGALFLLLFYTVRTRGSLLEQQQAALDAERKASDRAFEMIAAKNAFLG
MVSHELRTPLQAICGSIEVLLARPQSEANMKTIKRLQNSAASLEAQVKDLTDYIKLRSTNRSVQSEIVEVAPLLADVLDP
LRGRIRDKHLSTSLRVEPPALVVRSDRKLIQQIVSNLVENAIKYTNSGTIEISAALGGTPANRTMTITVRDTGVGIARHL
LAKIFEPFFRVNDPGVRHVDGIGMGLAVVQELVVALRGHVDVRSAVGEGSEFAVTLPVELPGRADALDDDAQPSPRAAHR
DLRALVVDDNENARETLGAMLATLGIRVDLRGTGKEGLRCFGECQHDIVVLDLELPDISGFEVAEQIRWATSSDAARKTT
ILGVSAYESALLKGDHAIFDAFIPKPIHLDTLGGIVSRLRS

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=389, Percent_Identity=27.2493573264781, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI87081816, Length=400, Percent_Identity=28.5, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI48994928, Length=336, Percent_Identity=30.952380952381, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI145693157, Length=262, Percent_Identity=32.824427480916, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1789149, Length=250, Percent_Identity=32.8, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=27.5862068965517, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=29.646017699115, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787894, Length=241, Percent_Identity=28.2157676348548, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082128, Length=237, Percent_Identity=27.4261603375527, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790346, Length=229, Percent_Identity=27.9475982532751, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790861, Length=217, Percent_Identity=30.8755760368664, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786783, Length=314, Percent_Identity=22.6114649681529, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790436, Length=312, Percent_Identity=26.2820512820513, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789808, Length=247, Percent_Identity=27.9352226720648, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1786912, Length=277, Percent_Identity=26.3537906137184, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=274, Percent_Identity=24.8175182481752, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66519; Mature: 66388

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVEWRNEKIIVALGSLWILGFAAWAFLLYDLLGTSVKEGILEGPREGVFWTAAQYRNS
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHH
FSRFDRQLILYAAGENRDFDAVLLQLDSLEASFGFLERPSEVSAYWLSIPKARGDIAELS
HHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHEEECCCCCCCHHHHH
RFMASLRRDVPALRARPDDTKRVLGELARQWPKVNALANYFRAIEMEQRDFTFHQLKEKR
HHHHHHHHCCHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
RAIVMLGGVLGIILGALFLLLFYTVRTRGSLLEQQQAALDAERKASDRAFEMIAAKNAFL
HHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMVSHELRTPLQAICGSIEVLLARPQSEANMKTIKRLQNSAASLEAQVKDLTDYIKLRST
HHHHHHHCCHHHHHHCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NRSVQSEIVEVAPLLADVLDPLRGRIRDKHLSTSLRVEPPALVVRSDRKLIQQIVSNLVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECHHHHHHHHHHHHHH
NAIKYTNSGTIEISAALGGTPANRTMTITVRDTGVGIARHLLAKIFEPFFRVNDPGVRHV
HHHHHCCCCCEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
DGIGMGLAVVQELVVALRGHVDVRSAVGEGSEFAVTLPVELPGRADALDDDAQPSPRAAH
CCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHH
RDLRALVVDDNENARETLGAMLATLGIRVDLRGTGKEGLRCFGECQHDIVVLDLELPDIS
CCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCCCCCEEEEEEECCCCC
GFEVAEQIRWATSSDAARKTTILGVSAYESALLKGDHAIFDAFIPKPIHLDTLGGIVSRL
CHHHHHHHHCCCCCCCCHHEEEEEEHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHH
RS
CC
>Mature Secondary Structure 
SRVEWRNEKIIVALGSLWILGFAAWAFLLYDLLGTSVKEGILEGPREGVFWTAAQYRNS
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHH
FSRFDRQLILYAAGENRDFDAVLLQLDSLEASFGFLERPSEVSAYWLSIPKARGDIAELS
HHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHEEECCCCCCCHHHHH
RFMASLRRDVPALRARPDDTKRVLGELARQWPKVNALANYFRAIEMEQRDFTFHQLKEKR
HHHHHHHHCCHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
RAIVMLGGVLGIILGALFLLLFYTVRTRGSLLEQQQAALDAERKASDRAFEMIAAKNAFL
HHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMVSHELRTPLQAICGSIEVLLARPQSEANMKTIKRLQNSAASLEAQVKDLTDYIKLRST
HHHHHHHCCHHHHHHCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NRSVQSEIVEVAPLLADVLDPLRGRIRDKHLSTSLRVEPPALVVRSDRKLIQQIVSNLVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECHHHHHHHHHHHHHH
NAIKYTNSGTIEISAALGGTPANRTMTITVRDTGVGIARHLLAKIFEPFFRVNDPGVRHV
HHHHHCCCCCEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
DGIGMGLAVVQELVVALRGHVDVRSAVGEGSEFAVTLPVELPGRADALDDDAQPSPRAAH
CCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHH
RDLRALVVDDNENARETLGAMLATLGIRVDLRGTGKEGLRCFGECQHDIVVLDLELPDIS
CCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCCCCCEEEEEEECCCCC
GFEVAEQIRWATSSDAARKTTILGVSAYESALLKGDHAIFDAFIPKPIHLDTLGGIVSRL
CHHHHHHHHCCCCCCCCHHEEEEEEHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHH
RS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA