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The map label for this gene is plsC [H]

Identifier: 53718308

GI number: 53718308

Start: 756145

End: 756924

Strand: Reverse

Name: plsC [H]

Synonym: BPSL0665

Alternate gene names: 53718308

Gene position: 756924-756145 (Counterclockwise)

Preceding gene: 53718309

Following gene: 53718307

Centisome position: 18.58

GC content: 67.44

Gene sequence:

>780_bases
ATGCGCTTCGTCCGCTCCCTGCTGCTGTTCGTCTATTTCATCGTCTATACGGTGCCGTACGCCACCGCATGCTTCATCGC
GTTCCCGTTCATGCGGCCGAACGCGCGCTACTGGATGGCGGTCGGCTGGTGCAAATCGACGCTGTTCGTCGCGCGCTGGC
TCACGGGTATCCGGTACCGCGTCGAAGGCTACGAGAACCTGCCCGACGGCCCGGCCGTGCTGCTGCCGAAGCATCAGTCC
GCATGGGAGACGATCGCGCTGCCCGCGCTGATGCCCAAGCCGCTCTGCTACGTGTTCAAGCGCGAGCTGCTGTACGTGCC
GTTCTTCGGCTGGGCGCTCGGGATGCTGCACATGGTCCACATCAACCGCAAGGACGGCAAGAACGCATTCGATTCGGTGA
TCCGCCAGGGCCGCAAGCGGATGGCGGAAGGCGCGTGGGTCATCATGTTCCCCGAGGGGACGCGCACGCCGGTCGGCAGC
CAGGGCAAGTACAAGACGGGCGGCGCGCGCTTCGCGATCGGCGCCGGCGCGCCCGTCGTGCCGATCGCGCACAACGCCGG
GCGCGTGTGGCCGCGCAACTCGTTCACGAAGTACCCCGGCACCGTCACGGTGTCGATCGGCCAGCCGATCGACACGCAAG
GCCTCACCCCCGACCAATTGAACGAACGCGTCGAAAACTGGATCGAAGCGGAAATGCGCCGCATCGATCCGCACGCGTAC
CGGCACGAGCGCGACGGCGCACGCGGCGCCGCCCGCGCGTCCGACGCCGCGCATCCCTGA

Upstream 100 bases:

>100_bases
CGTGCACGACGATCTGCGCGCGTTCGCGCTCGATTTCCTTTCCGAAGAACACGAGTGATGCCGACCCGCGCGCGTCCTCC
CTCACCGTAACGTCACGCCG

Downstream 100 bases:

>100_bases
AGTCAAGCGAGTTTCACCCATTGCGCACTGCCAAACGAAGCGAACTGATGCCGAAGCGTCCCAGGCCACGGCCGGCCGTC
GTGGCTCTCGATCACCGCCA

Product: putative acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MRFVRSLLLFVYFIVYTVPYATACFIAFPFMRPNARYWMAVGWCKSTLFVARWLTGIRYRVEGYENLPDGPAVLLPKHQS
AWETIALPALMPKPLCYVFKRELLYVPFFGWALGMLHMVHINRKDGKNAFDSVIRQGRKRMAEGAWVIMFPEGTRTPVGS
QGKYKTGGARFAIGAGAPVVPIAHNAGRVWPRNSFTKYPGTVTVSIGQPIDTQGLTPDQLNERVENWIEAEMRRIDPHAY
RHERDGARGAARASDAAHP

Sequences:

>Translated_259_residues
MRFVRSLLLFVYFIVYTVPYATACFIAFPFMRPNARYWMAVGWCKSTLFVARWLTGIRYRVEGYENLPDGPAVLLPKHQS
AWETIALPALMPKPLCYVFKRELLYVPFFGWALGMLHMVHINRKDGKNAFDSVIRQGRKRMAEGAWVIMFPEGTRTPVGS
QGKYKTGGARFAIGAGAPVVPIAHNAGRVWPRNSFTKYPGTVTVSIGQPIDTQGLTPDQLNERVENWIEAEMRRIDPHAY
RHERDGARGAARASDAAHP
>Mature_259_residues
MRFVRSLLLFVYFIVYTVPYATACFIAFPFMRPNARYWMAVGWCKSTLFVARWLTGIRYRVEGYENLPDGPAVLLPKHQS
AWETIALPALMPKPLCYVFKRELLYVPFFGWALGMLHMVHINRKDGKNAFDSVIRQGRKRMAEGAWVIMFPEGTRTPVGS
QGKYKTGGARFAIGAGAPVVPIAHNAGRVWPRNSFTKYPGTVTVSIGQPIDTQGLTPDQLNERVENWIEAEMRRIDPHAY
RHERDGARGAARASDAAHP

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=194, Percent_Identity=28.8659793814433, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI15100175, Length=194, Percent_Identity=28.8659793814433, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI6041665, Length=210, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1789395, Length=185, Percent_Identity=28.1081081081081, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17564032, Length=183, Percent_Identity=30.6010928961749, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320151, Length=183, Percent_Identity=29.5081967213115, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281364648, Length=195, Percent_Identity=29.2307692307692, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582856, Length=195, Percent_Identity=29.2307692307692, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582854, Length=195, Percent_Identity=29.2307692307692, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641614, Length=228, Percent_Identity=25, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641612, Length=228, Percent_Identity=25, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 29286; Mature: 29286

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVRSLLLFVYFIVYTVPYATACFIAFPFMRPNARYWMAVGWCKSTLFVARWLTGIRYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHEEE
VEGYENLPDGPAVLLPKHQSAWETIALPALMPKPLCYVFKRELLYVPFFGWALGMLHMVH
ECCCCCCCCCCEEEECCCCCCHHHHCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHE
INRKDGKNAFDSVIRQGRKRMAEGAWVIMFPEGTRTPVGSQGKYKTGGARFAIGAGAPVV
ECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCEE
PIAHNAGRVWPRNSFTKYPGTVTVSIGQPIDTQGLTPDQLNERVENWIEAEMRRIDPHAY
EEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHH
RHERDGARGAARASDAAHP
HCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRFVRSLLLFVYFIVYTVPYATACFIAFPFMRPNARYWMAVGWCKSTLFVARWLTGIRYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHEEE
VEGYENLPDGPAVLLPKHQSAWETIALPALMPKPLCYVFKRELLYVPFFGWALGMLHMVH
ECCCCCCCCCCEEEECCCCCCHHHHCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHE
INRKDGKNAFDSVIRQGRKRMAEGAWVIMFPEGTRTPVGSQGKYKTGGARFAIGAGAPVV
ECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCEE
PIAHNAGRVWPRNSFTKYPGTVTVSIGQPIDTQGLTPDQLNERVENWIEAEMRRIDPHAY
EEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHH
RHERDGARGAARASDAAHP
HCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434 [H]