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The map label for this gene is rhbA [H]

Identifier: 53718115

GI number: 53718115

Start: 516794

End: 518146

Strand: Reverse

Name: rhbA [H]

Synonym: BPSL0476

Alternate gene names: 53718115

Gene position: 518146-516794 (Counterclockwise)

Preceding gene: 53718116

Following gene: 53718114

Centisome position: 12.72

GC content: 72.28

Gene sequence:

>1353_bases
ATGCAAGACGTCGATCCCGCCTATGCCTTCGTCCGCGCCCGCGAATCGGGCGCGCGCACCTATGCGGACACCTTCGACAC
CGTTTTCGCGCACGGCGCGGGCACGGTGCTCACCGATACGGCCGGGCGCCGCTATCTCGATTTCCTGTCGTGCGCGGGCA
CGCTCGCCACGGGCCACAATCATCCGGCTGTCGTCGAGCGCGTGCGCGCGTTCGTCGACAGCGGCCAGGCGATGCAGATG
CTCGACATGACGACGCCCGTCAAGCACCGCTTCGTCGAGCGCCTGTTCGGAATCCTGCCGCCCGCGCTCGCGCGGCACGC
GCGCGTGCAGTTCTGCGGGCCGTCCGGCGCGGATGCGATCGAGGCGGCGATCAAGCTCTTCAAGACGGCCACCGGCCGGC
GCTCGGTGATCGCGTTCCACGGCGGCTATCACGGGATGACGGCGGGCGCGCTCGCGCTGACGGGCAACCTGCGCGCGAAG
CACGCGGTCGCGTCGCTGATGCCCGACGTGCACGTGATGCCGTATCCGTACGCGTACCGCTGCCCGTTCGGGCTCGGCGC
GCCGCACACCGCGGCCGCGTCGCTGCACTACATCGAATCGATGCTGAGCGATCCGGAAAGCGGTATCGCGAAACCCGCGT
GCGTGATCGTCGAAGCGGTGCAGGGCGAAGGCGGCGTGATTCCCGCGCCGCCCGAATGGCTCGCCGGGCTGCGCGCGTTG
ACCGCGCGGCTCGACATCGCGCTCGTGATCGACGAAGTGCAGACGGGCATCGGCCGCACGGGCGCGATGTTCGCGTTCGA
GCACAGCGGGATCCGGCCCGACGCCGTCGTGCTGTCGAAGGCGATCGGCGGCGGCTTTCCGCTCGCGCTCGTCGCCTATG
ACGAACGCTACGACGTCTGGGAGGCGGGCGCGCACGCGGGCACGTTCCGCGGCAACCAGATCGCGATGGCCGCGGGCGTC
GCGTGTCTCGACGTGATCGAATCGGAAGGGCTGATCGCCGGCGCGGCGGCCAAGGAGGCGCACGTGCGCGCGCGGCTCGA
GCGGCTCGCCGCGCGCCATCCGGAGATCGGCGACGTGCGCGGCCGCGGCCTCATGTGGGGAATCGAGCTCGTCGATCCCG
ACGCCGCGCCCGACGCGGCCGGCGCGCGTCCCGCCGCGCCCGCGCTCGCGCGCGCGCTCAAGCGGTATTGCTTCGCGCAC
GGGCTCATCGTCGAGACGGGCGGGCGCCACGGTGCGGTCGTGCGCCTGCTGCCGCCCCTCACCGTCAGCGCCGCCGAGCT
CGATCTCGCCTTCGACACGCTCGACGCCGGGCTCGCCGCGCTCGGCGAGCACGCGCGCGCCGAGTTCGCATGA

Upstream 100 bases:

>100_bases
CGCTGATCCTGCTGCACAAACGGCTGCGGCGCGGCGCGCTCGCGCCGAGCGCGTGATCCGCGGGGAGTCGCCCCGCCCTT
TCTTCGTGAGGTAGGTAGCC

Downstream 100 bases:

>100_bases
CGCGCCGCGCCGGCTCACCTTACGACTCTTCAAGGACACACGATCATGTCTTCCGGAATCGCCCCCCCGCACTCCGTGAA
CTACCGCAAGAAATACGCAA

Product: putative diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MQDVDPAYAFVRARESGARTYADTFDTVFAHGAGTVLTDTAGRRYLDFLSCAGTLATGHNHPAVVERVRAFVDSGQAMQM
LDMTTPVKHRFVERLFGILPPALARHARVQFCGPSGADAIEAAIKLFKTATGRRSVIAFHGGYHGMTAGALALTGNLRAK
HAVASLMPDVHVMPYPYAYRCPFGLGAPHTAAASLHYIESMLSDPESGIAKPACVIVEAVQGEGGVIPAPPEWLAGLRAL
TARLDIALVIDEVQTGIGRTGAMFAFEHSGIRPDAVVLSKAIGGGFPLALVAYDERYDVWEAGAHAGTFRGNQIAMAAGV
ACLDVIESEGLIAGAAAKEAHVRARLERLAARHPEIGDVRGRGLMWGIELVDPDAAPDAAGARPAAPALARALKRYCFAH
GLIVETGGRHGAVVRLLPPLTVSAAELDLAFDTLDAGLAALGEHARAEFA

Sequences:

>Translated_450_residues
MQDVDPAYAFVRARESGARTYADTFDTVFAHGAGTVLTDTAGRRYLDFLSCAGTLATGHNHPAVVERVRAFVDSGQAMQM
LDMTTPVKHRFVERLFGILPPALARHARVQFCGPSGADAIEAAIKLFKTATGRRSVIAFHGGYHGMTAGALALTGNLRAK
HAVASLMPDVHVMPYPYAYRCPFGLGAPHTAAASLHYIESMLSDPESGIAKPACVIVEAVQGEGGVIPAPPEWLAGLRAL
TARLDIALVIDEVQTGIGRTGAMFAFEHSGIRPDAVVLSKAIGGGFPLALVAYDERYDVWEAGAHAGTFRGNQIAMAAGV
ACLDVIESEGLIAGAAAKEAHVRARLERLAARHPEIGDVRGRGLMWGIELVDPDAAPDAAGARPAAPALARALKRYCFAH
GLIVETGGRHGAVVRLLPPLTVSAAELDLAFDTLDAGLAALGEHARAEFA
>Mature_450_residues
MQDVDPAYAFVRARESGARTYADTFDTVFAHGAGTVLTDTAGRRYLDFLSCAGTLATGHNHPAVVERVRAFVDSGQAMQM
LDMTTPVKHRFVERLFGILPPALARHARVQFCGPSGADAIEAAIKLFKTATGRRSVIAFHGGYHGMTAGALALTGNLRAK
HAVASLMPDVHVMPYPYAYRCPFGLGAPHTAAASLHYIESMLSDPESGIAKPACVIVEAVQGEGGVIPAPPEWLAGLRAL
TARLDIALVIDEVQTGIGRTGAMFAFEHSGIRPDAVVLSKAIGGGFPLALVAYDERYDVWEAGAHAGTFRGNQIAMAAGV
ACLDVIESEGLIAGAAAKEAHVRARLERLAARHPEIGDVRGRGLMWGIELVDPDAAPDAAGARPAAPALARALKRYCFAH
GLIVETGGRHGAVVRLLPPLTVSAAELDLAFDTLDAGLAALGEHARAEFA

Specific function: 4-aminobutyrate (GABA) degradation. [C]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=428, Percent_Identity=29.6728971962617, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI37574042, Length=420, Percent_Identity=27.8571428571429, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4557809, Length=449, Percent_Identity=27.1714922048998, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI24119277, Length=429, Percent_Identity=27.972027972028, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI226442709, Length=398, Percent_Identity=27.6381909547739, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI226442705, Length=419, Percent_Identity=26.9689737470167, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI284507298, Length=340, Percent_Identity=27.3529411764706, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI188536080, Length=381, Percent_Identity=24.4094488188976, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI38679950, Length=381, Percent_Identity=24.4094488188976, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI38679946, Length=381, Percent_Identity=24.4094488188976, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1789016, Length=399, Percent_Identity=37.0927318295739, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1787560, Length=421, Percent_Identity=33.4916864608076, Blast_Score=178, Evalue=7e-46,
Organism=Escherichia coli, GI145693181, Length=419, Percent_Identity=29.8329355608592, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1788044, Length=412, Percent_Identity=31.5533980582524, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1789759, Length=407, Percent_Identity=28.7469287469287, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786349, Length=305, Percent_Identity=33.1147540983607, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786991, Length=424, Percent_Identity=27.8301886792453, Blast_Score=112, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI32564660, Length=442, Percent_Identity=32.1266968325792, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI71992977, Length=433, Percent_Identity=28.175519630485, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25144271, Length=437, Percent_Identity=25.629290617849, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25144274, Length=263, Percent_Identity=28.8973384030418, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17541228, Length=464, Percent_Identity=26.0775862068966, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324432, Length=442, Percent_Identity=29.185520361991, Blast_Score=167, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6323470, Length=440, Percent_Identity=28.1818181818182, Blast_Score=144, Evalue=4e-35,
Organism=Drosophila melanogaster, GI161085790, Length=423, Percent_Identity=31.6784869976359, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28574759, Length=422, Percent_Identity=31.7535545023697, Blast_Score=163, Evalue=3e-40,
Organism=Drosophila melanogaster, GI21356575, Length=414, Percent_Identity=29.4685990338164, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI21357415, Length=448, Percent_Identity=23.8839285714286, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI281366494, Length=460, Percent_Identity=24.3478260869565, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24667139, Length=460, Percent_Identity=24.3478260869565, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24667143, Length=460, Percent_Identity=24.3478260869565, Blast_Score=94, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 47315; Mature: 47315

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDVDPAYAFVRARESGARTYADTFDTVFAHGAGTVLTDTAGRRYLDFLSCAGTLATGHN
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCC
HPAVVERVRAFVDSGQAMQMLDMTTPVKHRFVERLFGILPPALARHARVQFCGPSGADAI
CHHHHHHHHHHHCCCCCEEHHHCCCHHHHHHHHHHHHHCCHHHHHCCEEEEECCCCCHHH
EAAIKLFKTATGRRSVIAFHGGYHGMTAGALALTGNLRAKHAVASLMPDVHVMPYPYAYR
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHCCCCEECCCCCEEE
CPFGLGAPHTAAASLHYIESMLSDPESGIAKPACVIVEAVQGEGGVIPAPPEWLAGLRAL
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
TARLDIALVIDEVQTGIGRTGAMFAFEHSGIRPDAVVLSKAIGGGFPLALVAYDERYDVW
HHHHHHEEEEEHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHH
EAGAHAGTFRGNQIAMAAGVACLDVIESEGLIAGAAAKEAHVRARLERLAARHPEIGDVR
HCCCCCCCCCCCEEEHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCC
GRGLMWGIELVDPDAAPDAAGARPAAPALARALKRYCFAHGLIVETGGRHGAVVRLLPPL
CCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEECCC
TVSAAELDLAFDTLDAGLAALGEHARAEFA
EECHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQDVDPAYAFVRARESGARTYADTFDTVFAHGAGTVLTDTAGRRYLDFLSCAGTLATGHN
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCC
HPAVVERVRAFVDSGQAMQMLDMTTPVKHRFVERLFGILPPALARHARVQFCGPSGADAI
CHHHHHHHHHHHCCCCCEEHHHCCCHHHHHHHHHHHHHCCHHHHHCCEEEEECCCCCHHH
EAAIKLFKTATGRRSVIAFHGGYHGMTAGALALTGNLRAKHAVASLMPDVHVMPYPYAYR
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHCCCCEECCCCCEEE
CPFGLGAPHTAAASLHYIESMLSDPESGIAKPACVIVEAVQGEGGVIPAPPEWLAGLRAL
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
TARLDIALVIDEVQTGIGRTGAMFAFEHSGIRPDAVVLSKAIGGGFPLALVAYDERYDVW
HHHHHHEEEEEHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHH
EAGAHAGTFRGNQIAMAAGVACLDVIESEGLIAGAAAKEAHVRARLERLAARHPEIGDVR
HCCCCCCCCCCCEEEHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCC
GRGLMWGIELVDPDAAPDAAGARPAAPALARALKRYCFAHGLIVETGGRHGAVVRLLPPL
CCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEECCC
TVSAAELDLAFDTLDAGLAALGEHARAEFA
EECHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11274118; 11481432 [H]