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The map label for this gene is bioD [H]

Identifier: 53718005

GI number: 53718005

Start: 393751

End: 394473

Strand: Reverse

Name: bioD [H]

Synonym: BPSL0365

Alternate gene names: 53718005

Gene position: 394473-393751 (Counterclockwise)

Preceding gene: 53718006

Following gene: 53718004

Centisome position: 9.68

GC content: 74.14

Gene sequence:

>723_bases
ATGAGCGCGCCGCTTTCGCTGTTCGTGACGGGCACCGATACCGAGATCGGCAAGACGTTCGTATCGGCCGCGCTGCTGCA
CGGCTTCGCGCGCGCGGGGCTGCGCGCGGCCGCGATGAAGCCGGTGGCCGCGGGCGCGTACGAGCGCGACGGCGCATGGC
GCAACGAAGACGCGGACCAGCTCGACGCGGCCGCGAACGTCGCGCTGCCCGCCGCGATCCGCACGCCGTTTCTCCTGAAG
GCGCCCGCCGCGCCGCACATCGTCGCCGCGCGCGAGGGCGTCGCGCTCGACATCGGCACGATCGTCGACGCGCATCGCCG
CGCGTGCGAGATGGCGGACGTCATCGTCGTCGAAGGCGTCGGCGGCTTTCGCGTGCCGCTCGCCGACACGCGCGATACCG
CCGATCTGGCGGTCGCGCTCGGGCTGCCCGTGGTGCTCGTCGTCGGCGTGCGTCTCGGCTGCATCAGCCACGCACTGCTC
ACCGCCGAGGCGATCGCCGCGCGCGGCCTGCCCCTTGCCGGCTGGGTCGCGAACCGCATCGATCCGGCGATGCCCTTCGC
CGACGACAACATCGACACGCTGCGCGCGTGGCTCGAACGCGAGCACCGCGCGCCGCTGCTCGGCGCGCTCGCGCACATGA
GCCCGCCGTCGCCCGACGCGGCGTCGCACGCGCTCGACGTGAACCTCTTGCTGAACGCGCTGCGCGCCGCCGCGCCGCGC
TGA

Upstream 100 bases:

>100_bases
CCGGCACGTCGCGGCTGCGCATCTCGCTGTCGGCCGCGCATTCGTTCGACGATCTCGCACGCCTCGAGGCGGCGCTCGTC
ACGCCGATCGGAGCCGCCGC

Downstream 100 bases:

>100_bases
CGTTTTAGCCGCTCGTTTCAACCGCTCTTTGCCGATTTTTCGCATCGATCCCTGTTCCGAAGGATGACCGACATGACTGA
AGCTCAAACCGCTTGCGCGA

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSAPLSLFVTGTDTEIGKTFVSAALLHGFARAGLRAAAMKPVAAGAYERDGAWRNEDADQLDAAANVALPAAIRTPFLLK
APAAPHIVAAREGVALDIGTIVDAHRRACEMADVIVVEGVGGFRVPLADTRDTADLAVALGLPVVLVVGVRLGCISHALL
TAEAIAARGLPLAGWVANRIDPAMPFADDNIDTLRAWLEREHRAPLLGALAHMSPPSPDAASHALDVNLLLNALRAAAPR

Sequences:

>Translated_240_residues
MSAPLSLFVTGTDTEIGKTFVSAALLHGFARAGLRAAAMKPVAAGAYERDGAWRNEDADQLDAAANVALPAAIRTPFLLK
APAAPHIVAAREGVALDIGTIVDAHRRACEMADVIVVEGVGGFRVPLADTRDTADLAVALGLPVVLVVGVRLGCISHALL
TAEAIAARGLPLAGWVANRIDPAMPFADDNIDTLRAWLEREHRAPLLGALAHMSPPSPDAASHALDVNLLLNALRAAAPR
>Mature_239_residues
SAPLSLFVTGTDTEIGKTFVSAALLHGFARAGLRAAAMKPVAAGAYERDGAWRNEDADQLDAAANVALPAAIRTPFLLKA
PAAPHIVAAREGVALDIGTIVDAHRRACEMADVIVVEGVGGFRVPLADTRDTADLAVALGLPVVLVVGVRLGCISHALLT
AEAIAARGLPLAGWVANRIDPAMPFADDNIDTLRAWLEREHRAPLLGALAHMSPPSPDAASHALDVNLLLNALRAAAPR

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=225, Percent_Identity=43.1111111111111, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI87081944, Length=230, Percent_Identity=39.1304347826087, Blast_Score=144, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6324385, Length=171, Percent_Identity=33.9181286549708, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24922; Mature: 24791

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPLSLFVTGTDTEIGKTFVSAALLHGFARAGLRAAAMKPVAAGAYERDGAWRNEDADQ
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCHHH
LDAAANVALPAAIRTPFLLKAPAAPHIVAAREGVALDIGTIVDAHRRACEMADVIVVEGV
HHHHHHHHCCHHHCCCEEEECCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHCEEEEECC
GGFRVPLADTRDTADLAVALGLPVVLVVGVRLGCISHALLTAEAIAARGLPLAGWVANRI
CCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
DPAMPFADDNIDTLRAWLEREHRAPLLGALAHMSPPSPDAASHALDVNLLLNALRAAAPR
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SAPLSLFVTGTDTEIGKTFVSAALLHGFARAGLRAAAMKPVAAGAYERDGAWRNEDADQ
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCHHH
LDAAANVALPAAIRTPFLLKAPAAPHIVAAREGVALDIGTIVDAHRRACEMADVIVVEGV
HHHHHHHHCCHHHCCCEEEECCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHCEEEEECC
GGFRVPLADTRDTADLAVALGLPVVLVVGVRLGCISHALLTAEAIAARGLPLAGWVANRI
CCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
DPAMPFADDNIDTLRAWLEREHRAPLLGALAHMSPPSPDAASHALDVNLLLNALRAAAPR
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA