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The map label for this gene is yjcE [H]

Identifier: 53717997

GI number: 53717997

Start: 383345

End: 385012

Strand: Reverse

Name: yjcE [H]

Synonym: BPSL0357

Alternate gene names: 53717997

Gene position: 385012-383345 (Counterclockwise)

Preceding gene: 53718004

Following gene: 53717989

Centisome position: 9.45

GC content: 69.96

Gene sequence:

>1668_bases
ATGGCAATCGTCTTCACTGTTTTGATCCTGTTGCTCGCGGTCGCGCTGTCCGGCGTCGCGACGCGCGTGCTACCGCTGCG
GCTGCCGTTGCCGCTGATGCAGATCGCGATCGGCGCCGTGCTCGCGTGGCCCCGGTTCAACCTGCACGTCACGTTCGACC
CCGAAATCTTCATGCTGCTGTTCATTCCGCCGCTGCTGTTCGCGGACGGCTGGCGCATTCCGAAGCGCGAGCTGTACCTG
CAGCGGCGCGCGATCCTGATGCTCGCGTTCGGCCTCGTGTTCATGACGGTACTCGCGGTCGGCTACTTCGCGCATGGGTT
GATTCCCGGCCTGCCGCTGCCCATCGCGTTCGCGCTCGCCGCGGTGCTCTCGCCGACCGACGCGGTCGCGCTCGCCGGCA
TCGCCGGCAAGGGTCGCATCCCGCCGCAACTGATGCACATCCTGGAAGGCGAGGCGCTGATGAACGACGCGTCGGGCCTC
GTCGCGCTCAAGTTCGCGATCGCGGCCGCGCTGACCGGCATGTTCTCGCTGCGCGACGCGTCGATCAGCTTCGTGATCGT
CGCATCGGGCGGCCTCGCGGCGGGCGCGGCGCTCGCGTGGCTGTTCAGCGCGCTGTCGACGCGCTTCCTGAACGCCGCGC
AGGAAGGCGACCCCGCGCCCGGCATCGTGATGACGCTGCTCGTGCCGTTCGCGTCGTATCTCATCGCAGAGCATCTCGGA
TTGTCGGGAATCCTGTCGGCCGTCGCCTCCGGGATGATGATGAACTACACCAGCTTCTCGAAGAGCAGCACGGTCGCCGC
GCGCGTGCGCGCGGAAAGCACGTGGGCGATGATCGAGTTCGTGTTCAACGGAATGGTGTTCATCATGCTCGGGCTGCAGT
TGCCGCACATCATCGGCCGTGCGCTCGTCGATGCGCACCACACGAGCGACGCGCTCGTCGGCGCGATGATCGGCTACGTC
GCCGCGATGCTCGCCGCGCTCTACGCGATCCGCTTCACGTGGGTGTGGCTGCTGCGCTGGATCGCGAGCCGCCGCGCGGC
GAAGCAGGGGCTCGCCGGCACGATGGCGGGCCTGCGCACGATCGCCGTGATGACCGTGGGCGGCGTGCGCGGCGCGATCA
CGCTCGCGGGCGTGCTGTCGATTCCGGTCGCGCTCGGCGACGGCACGCCGCTCGCGGGCCGCGACACCGCGATCTTCGTC
GCGTCGGGCGTGATCCTCGGCTCGCTCGTCGTCGCGGTGATCGCGCTGCCGCTGCTGCTGCGCGGTGTGCGCCCGATGCG
CAATCCGCACGCGGAGGAGGAGCGCGCCGCGCGCGCGGCGGCCGCGCAGGCGGCGATCCGCGCGGTGGACGCGGCGCACG
ACGCGCTCGCCGTCGATCTCGACGAATCGGCCGCCGCGCGCTGCGCGGACGTGACCGCGCGCGTGATGGACCTGTACCGC
CGCCGGCTCGCGGGCCTCGCCGCCGACGGCGCGACGCCGCGCGAGGAAGCGCGACAGACGGAGAAGATGGAGCTGGCGCT
GAAGATCGCGGCGATCCGCGCGGAGCGTGCGGTGCTCTACCGGCTGCGCGGCGAGCAGAAGATCAACGACGAGACGCTGG
CGAAGCTGATGCGCGAAGTCGATTTTTCGGAGACGGCGCTGTCGACGCGCAAGAAGGGCATCGTCTGA

Upstream 100 bases:

>100_bases
CACCACCATAGTGCGCCCGCGCTCGCGCCCCGCTTCACGCCGCGCATTTCGCGCGCACGCTACACTGCGTACCGTCGTTT
CATCCCCGTTTCGAATATCG

Downstream 100 bases:

>100_bases
CGCCGCAAGCGCCGCCGTGTCGGACAACTGACGAACGGCGGCGAAGGGATGAAGGGATGAAGGGATGAAGCGGCGAAGCG
GCGAAGCGGCGAAGCGGCGA

Product: sodium/hydrogen exchanger family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MAIVFTVLILLLAVALSGVATRVLPLRLPLPLMQIAIGAVLAWPRFNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYL
QRRAILMLAFGLVFMTVLAVGYFAHGLIPGLPLPIAFALAAVLSPTDAVALAGIAGKGRIPPQLMHILEGEALMNDASGL
VALKFAIAAALTGMFSLRDASISFVIVASGGLAAGAALAWLFSALSTRFLNAAQEGDPAPGIVMTLLVPFASYLIAEHLG
LSGILSAVASGMMMNYTSFSKSSTVAARVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRALVDAHHTSDALVGAMIGYV
AAMLAALYAIRFTWVWLLRWIASRRAAKQGLAGTMAGLRTIAVMTVGGVRGAITLAGVLSIPVALGDGTPLAGRDTAIFV
ASGVILGSLVVAVIALPLLLRGVRPMRNPHAEEERAARAAAAQAAIRAVDAAHDALAVDLDESAAARCADVTARVMDLYR
RRLAGLAADGATPREEARQTEKMELALKIAAIRAERAVLYRLRGEQKINDETLAKLMREVDFSETALSTRKKGIV

Sequences:

>Translated_555_residues
MAIVFTVLILLLAVALSGVATRVLPLRLPLPLMQIAIGAVLAWPRFNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYL
QRRAILMLAFGLVFMTVLAVGYFAHGLIPGLPLPIAFALAAVLSPTDAVALAGIAGKGRIPPQLMHILEGEALMNDASGL
VALKFAIAAALTGMFSLRDASISFVIVASGGLAAGAALAWLFSALSTRFLNAAQEGDPAPGIVMTLLVPFASYLIAEHLG
LSGILSAVASGMMMNYTSFSKSSTVAARVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRALVDAHHTSDALVGAMIGYV
AAMLAALYAIRFTWVWLLRWIASRRAAKQGLAGTMAGLRTIAVMTVGGVRGAITLAGVLSIPVALGDGTPLAGRDTAIFV
ASGVILGSLVVAVIALPLLLRGVRPMRNPHAEEERAARAAAAQAAIRAVDAAHDALAVDLDESAAARCADVTARVMDLYR
RRLAGLAADGATPREEARQTEKMELALKIAAIRAERAVLYRLRGEQKINDETLAKLMREVDFSETALSTRKKGIV
>Mature_554_residues
AIVFTVLILLLAVALSGVATRVLPLRLPLPLMQIAIGAVLAWPRFNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYLQ
RRAILMLAFGLVFMTVLAVGYFAHGLIPGLPLPIAFALAAVLSPTDAVALAGIAGKGRIPPQLMHILEGEALMNDASGLV
ALKFAIAAALTGMFSLRDASISFVIVASGGLAAGAALAWLFSALSTRFLNAAQEGDPAPGIVMTLLVPFASYLIAEHLGL
SGILSAVASGMMMNYTSFSKSSTVAARVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRALVDAHHTSDALVGAMIGYVA
AMLAALYAIRFTWVWLLRWIASRRAAKQGLAGTMAGLRTIAVMTVGGVRGAITLAGVLSIPVALGDGTPLAGRDTAIFVA
SGVILGSLVVAVIALPLLLRGVRPMRNPHAEEERAARAAAAQAAIRAVDAAHDALAVDLDESAAARCADVTARVMDLYRR
RLAGLAADGATPREEARQTEKMELALKIAAIRAERAVLYRLRGEQKINDETLAKLMREVDFSETALSTRKKGIV

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI27734935, Length=352, Percent_Identity=23.2954545454545, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI5454070, Length=267, Percent_Identity=24.3445692883895, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI110227626, Length=267, Percent_Identity=24.3445692883895, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI294997330, Length=267, Percent_Identity=24.3445692883895, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI14211919, Length=399, Percent_Identity=21.5538847117794, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI41872703, Length=322, Percent_Identity=25.776397515528, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI148727259, Length=311, Percent_Identity=26.0450160771704, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1790501, Length=555, Percent_Identity=48.8288288288288, Blast_Score=484, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI71980847, Length=404, Percent_Identity=25.990099009901, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71999819, Length=459, Percent_Identity=24.400871459695, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71999817, Length=459, Percent_Identity=24.400871459695, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71999821, Length=425, Percent_Identity=24.9411764705882, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25150332, Length=373, Percent_Identity=22.5201072386059, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71987535, Length=408, Percent_Identity=24.5098039215686, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71987537, Length=408, Percent_Identity=24.5098039215686, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71990932, Length=383, Percent_Identity=24.2819843342037, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71992107, Length=260, Percent_Identity=21.5384615384615, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6320663, Length=262, Percent_Identity=24.0458015267176, Blast_Score=63, Evalue=1e-10,
Organism=Drosophila melanogaster, GI281364513, Length=288, Percent_Identity=25.3472222222222, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221473212, Length=456, Percent_Identity=22.5877192982456, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221473222, Length=264, Percent_Identity=25.3787878787879, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221473215, Length=264, Percent_Identity=25.3787878787879, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281360447, Length=312, Percent_Identity=24.3589743589744, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221510738, Length=390, Percent_Identity=24.8717948717949, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221510734, Length=390, Percent_Identity=24.8717948717949, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 58891; Mature: 58760

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVFTVLILLLAVALSGVATRVLPLRLPLPLMQIAIGAVLAWPRFNLHVTFDPEIFMLL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHH
FIPPLLFADGWRIPKRELYLQRRAILMLAFGLVFMTVLAVGYFAHGLIPGLPLPIAFALA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AVLSPTDAVALAGIAGKGRIPPQLMHILEGEALMNDASGLVALKFAIAAALTGMFSLRDA
HHHCCCHHHHHCCCCCCCCCCHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
SISFVIVASGGLAAGAALAWLFSALSTRFLNAAQEGDPAPGIVMTLLVPFASYLIAEHLG
CEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
LSGILSAVASGMMMNYTSFSKSSTVAARVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGR
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVDAHHTSDALVGAMIGYVAAMLAALYAIRFTWVWLLRWIASRRAAKQGLAGTMAGLRT
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
IAVMTVGGVRGAITLAGVLSIPVALGDGTPLAGRDTAIFVASGVILGSLVVAVIALPLLL
HHHHHCCCCHHHHHHHHHHHHCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RGVRPMRNPHAEEERAARAAAAQAAIRAVDAAHDALAVDLDESAAARCADVTARVMDLYR
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHH
RRLAGLAADGATPREEARQTEKMELALKIAAIRAERAVLYRLRGEQKINDETLAKLMREV
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
DFSETALSTRKKGIV
CCHHHHHHHHHCCCC
>Mature Secondary Structure 
AIVFTVLILLLAVALSGVATRVLPLRLPLPLMQIAIGAVLAWPRFNLHVTFDPEIFMLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHH
FIPPLLFADGWRIPKRELYLQRRAILMLAFGLVFMTVLAVGYFAHGLIPGLPLPIAFALA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AVLSPTDAVALAGIAGKGRIPPQLMHILEGEALMNDASGLVALKFAIAAALTGMFSLRDA
HHHCCCHHHHHCCCCCCCCCCHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
SISFVIVASGGLAAGAALAWLFSALSTRFLNAAQEGDPAPGIVMTLLVPFASYLIAEHLG
CEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
LSGILSAVASGMMMNYTSFSKSSTVAARVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGR
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVDAHHTSDALVGAMIGYVAAMLAALYAIRFTWVWLLRWIASRRAAKQGLAGTMAGLRT
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
IAVMTVGGVRGAITLAGVLSIPVALGDGTPLAGRDTAIFVASGVILGSLVVAVIALPLLL
HHHHHCCCCHHHHHHHHHHHHCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RGVRPMRNPHAEEERAARAAAAQAAIRAVDAAHDALAVDLDESAAARCADVTARVMDLYR
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHH
RRLAGLAADGATPREEARQTEKMELALKIAAIRAERAVLYRLRGEQKINDETLAKLMREV
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
DFSETALSTRKKGIV
CCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]