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The map label for this gene is yhdG [H]

Identifier: 53717880

GI number: 53717880

Start: 248017

End: 249420

Strand: Reverse

Name: yhdG [H]

Synonym: BPSL0238

Alternate gene names: 53717880

Gene position: 249420-248017 (Counterclockwise)

Preceding gene: 53717881

Following gene: 53717879

Centisome position: 6.12

GC content: 67.74

Gene sequence:

>1404_bases
ATGTCTCTCTTCCGCAAGAAAAACGTCGACCGCATGATCGCCGGCGCGCAAGCGGCCGGCCTCAAGAAGGCGCTCGGCGC
GGTCGACCTCACCTTTCTCGGCATCGGCGCGATCATCGGCACCGGCATCTTCGTGCTGACCGGCACGGGCGCCGTGCAGG
CCGGGCCGGCGCTGATGCTGTCGTTCGTGATCGCGGCGATCGCGTGCGGCCTCGCCGCGCTGTCGTACGCCGAATTCGCG
TCGACGATCCCCGTCGCCGGCTCGATCTACACGTATTCGTACGCGACTCTCGGCGAGCTCGTCGCATGGATCATCGGCTG
GGACCTGATGCTCGAGTACGGGCTCGCCGCGTCCGCGGTGTCGGTCGGCTGGTCCGGCTACCTGCAATCGCTGCTGCAGG
GCTTCGGCGTGTCGCTGCCGACGGCGCTCACCGCCGCGCCGGGCGCGCTGCCGGGCGTCGTCACGTATTTCAACCTGCCC
GCGTTCGTCGTGATGCTCGTCATCACGACACTGCTGTCGATCGGCATCCGCGAATCGACGCGCGTGAACAACATCATGGT
GTTCATCAAGGTCGCCGTCGTGCTGCTCGTGATCGCGGTCGGCGTCTTCCACGTGACGCCCGCGAACTGGAAGCCGTTCA
TGCCGCACGGCTGGAACGGCGTGTTCGGCGCGGCGGCCGTGATGTTCTTCGCGTTCATCGGCTTCGACGCGGTGTCGTCG
GCCGCCGAGGAGGTGAAGAACCCGAAGCGCGATCTGCCGGTGGGCATCATCGCCTCGCTCGGCGTGTGCGCGTTCCTGTA
TGTCGCGGTCGCGGCGATCGCGACGGGCATCGTGCCGTGGGCCCAGTACGCGAACGTCTCGCATCCGATCTCGTACGCGC
TGCAGGTGGCGGGCGAGAAGTGGGTGGCGGGCTTCATCGATCTCGGCGCCGTCATCGGCATGTTGACCGTGATCCTCGTG
ATGAGCTACGGCCAGACCCGGATCATCTTCGCGATGTCGCGCGACGGCCTGCTGCCCGCCGCGCTCTCGCGCGTGCACCC
GCGCTTCGCGACGCCGTTCCTGACGACCTGGCTCGTCGGCCTGTTCTTCGGCCTGATCGCCGCGCTGATTCCGCTGAACG
TGCTCGCCGAGCTGATCAACATCGGCACGCTCGCCGCGTTCTCGATGGTGTCGATCGCGGTGCTCGTGCTGCGCCGCACG
CACCCGGATCTGCCGCGCGCGTTCCGCTGCCCGGGCGTGCCGCTCGTGCCGATCCTCGCGGTGGCCGCGTGCCTGTTCCT
GATGCTGAACCTGCAGCCGGTCACGTGGATCGCGTTCCTGACGTGGCTCGTGATCGGCCTGTTCGTGTACTTCGCGTACT
CGCGCAGCCGCTCGAAGCTCGCACACGGCGCGCAGCAGCACTGA

Upstream 100 bases:

>100_bases
TCGCGCATCGTCCGGCGCGGGCATGCCCGCCATATCCGCTAAAATGGCGGGTTTTCCACTTGTCCGGCGCGCGCCCCGCG
CCGTCCGGTAATCCCACGCA

Downstream 100 bases:

>100_bases
CGCGCGATCTCTCGCGGTGCGCGCCGTGCGCGGGCCGCATCGCTCGCGAACGCGCGCCGCGCTTGCCACGCCACGCTCCC
GGCTTCAGCGAGTTTTTTTG

Product: putative amino-acid transporter transmembrane protein

Products: L-tryptophan [Cytoplasm]; Proton [Cytoplasm]; Proton [Cytoplasm]; L-tyrosine [Cytoplasm]; Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSLFRKKNVDRMIAGAQAAGLKKALGAVDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFA
STIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLAASAVSVGWSGYLQSLLQGFGVSLPTALTAAPGALPGVVTYFNLP
AFVVMLVITTLLSIGIRESTRVNNIMVFIKVAVVLLVIAVGVFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSS
AAEEVKNPKRDLPVGIIASLGVCAFLYVAVAAIATGIVPWAQYANVSHPISYALQVAGEKWVAGFIDLGAVIGMLTVILV
MSYGQTRIIFAMSRDGLLPAALSRVHPRFATPFLTTWLVGLFFGLIAALIPLNVLAELINIGTLAAFSMVSIAVLVLRRT
HPDLPRAFRCPGVPLVPILAVAACLFLMLNLQPVTWIAFLTWLVIGLFVYFAYSRSRSKLAHGAQQH

Sequences:

>Translated_467_residues
MSLFRKKNVDRMIAGAQAAGLKKALGAVDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFA
STIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLAASAVSVGWSGYLQSLLQGFGVSLPTALTAAPGALPGVVTYFNLP
AFVVMLVITTLLSIGIRESTRVNNIMVFIKVAVVLLVIAVGVFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSS
AAEEVKNPKRDLPVGIIASLGVCAFLYVAVAAIATGIVPWAQYANVSHPISYALQVAGEKWVAGFIDLGAVIGMLTVILV
MSYGQTRIIFAMSRDGLLPAALSRVHPRFATPFLTTWLVGLFFGLIAALIPLNVLAELINIGTLAAFSMVSIAVLVLRRT
HPDLPRAFRCPGVPLVPILAVAACLFLMLNLQPVTWIAFLTWLVIGLFVYFAYSRSRSKLAHGAQQH
>Mature_466_residues
SLFRKKNVDRMIAGAQAAGLKKALGAVDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFAS
TIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLAASAVSVGWSGYLQSLLQGFGVSLPTALTAAPGALPGVVTYFNLPA
FVVMLVITTLLSIGIRESTRVNNIMVFIKVAVVLLVIAVGVFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSSA
AEEVKNPKRDLPVGIIASLGVCAFLYVAVAAIATGIVPWAQYANVSHPISYALQVAGEKWVAGFIDLGAVIGMLTVILVM
SYGQTRIIFAMSRDGLLPAALSRVHPRFATPFLTTWLVGLFFGLIAALIPLNVLAELINIGTLAAFSMVSIAVLVLRRTH
PDLPRAFRCPGVPLVPILAVAACLFLMLNLQPVTWIAFLTWLVIGLFVYFAYSRSRSKLAHGAQQH

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of The Aromatic Amino Acids (Phenylalanine, Tyrosine, And Tryptophan). [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=436, Percent_Identity=36.0091743119266, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI258645169, Length=426, Percent_Identity=34.7417840375587, Blast_Score=218, Evalue=7e-57,
Organism=Homo sapiens, GI258614005, Length=426, Percent_Identity=33.8028169014084, Blast_Score=218, Evalue=7e-57,
Organism=Homo sapiens, GI258614003, Length=426, Percent_Identity=33.8028169014084, Blast_Score=218, Evalue=8e-57,
Organism=Homo sapiens, GI181337167, Length=410, Percent_Identity=35.609756097561, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI110347453, Length=385, Percent_Identity=35.8441558441558, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI114326544, Length=431, Percent_Identity=32.9466357308585, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI114326550, Length=431, Percent_Identity=32.9466357308585, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI33286428, Length=476, Percent_Identity=26.890756302521, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI187423910, Length=492, Percent_Identity=25.609756097561, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI7657591, Length=492, Percent_Identity=25.609756097561, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI186910308, Length=413, Percent_Identity=25.6658595641646, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI186910306, Length=413, Percent_Identity=25.6658595641646, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI186910304, Length=413, Percent_Identity=25.6658595641646, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI115648063, Length=419, Percent_Identity=24.3436754176611, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI115648022, Length=419, Percent_Identity=24.3436754176611, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI7657683, Length=403, Percent_Identity=24.8138957816377, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI71979932, Length=420, Percent_Identity=26.1904761904762, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI9790235, Length=299, Percent_Identity=23.0769230769231, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1786302, Length=477, Percent_Identity=24.3186582809224, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082023, Length=450, Percent_Identity=25.7777777777778, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87081915, Length=429, Percent_Identity=22.6107226107226, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786789, Length=354, Percent_Identity=22.316384180791, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786602, Length=479, Percent_Identity=23.3820459290188, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788480, Length=452, Percent_Identity=26.3274336283186, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081869, Length=461, Percent_Identity=23.4273318872017, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081708, Length=481, Percent_Identity=23.0769230769231, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082250, Length=427, Percent_Identity=23.8875878220141, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789017, Length=458, Percent_Identity=22.2707423580786, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786694, Length=251, Percent_Identity=25.8964143426295, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790653, Length=420, Percent_Identity=20.4761904761905, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI48994972, Length=343, Percent_Identity=23.0320699708455, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=412, Percent_Identity=36.1650485436893, Blast_Score=245, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI17531343, Length=407, Percent_Identity=35.3808353808354, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17533459, Length=411, Percent_Identity=34.0632603406326, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17540018, Length=440, Percent_Identity=25.2272727272727, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17568033, Length=426, Percent_Identity=23.4741784037559, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193208714, Length=441, Percent_Identity=27.2108843537415, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32566695, Length=441, Percent_Identity=27.2108843537415, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17537453, Length=328, Percent_Identity=27.1341463414634, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32566699, Length=373, Percent_Identity=25.4691689008043, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71982612, Length=435, Percent_Identity=22.0689655172414, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71982608, Length=435, Percent_Identity=22.0689655172414, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24666159, Length=415, Percent_Identity=38.0722891566265, Blast_Score=274, Evalue=9e-74,
Organism=Drosophila melanogaster, GI221512776, Length=415, Percent_Identity=38.0722891566265, Blast_Score=274, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24667468, Length=403, Percent_Identity=35.9801488833747, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24668806, Length=429, Percent_Identity=34.2657342657343, Blast_Score=239, Evalue=4e-63,
Organism=Drosophila melanogaster, GI21356285, Length=429, Percent_Identity=34.2657342657343, Blast_Score=239, Evalue=4e-63,
Organism=Drosophila melanogaster, GI24668802, Length=429, Percent_Identity=34.2657342657343, Blast_Score=239, Evalue=4e-63,
Organism=Drosophila melanogaster, GI161077963, Length=424, Percent_Identity=35.1415094339623, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI281366235, Length=426, Percent_Identity=34.037558685446, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI116007820, Length=426, Percent_Identity=34.037558685446, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI116007818, Length=414, Percent_Identity=34.5410628019324, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI85725152, Length=414, Percent_Identity=34.5410628019324, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI21357367, Length=424, Percent_Identity=27.3584905660377, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221331183, Length=449, Percent_Identity=24.9443207126949, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI17647653, Length=449, Percent_Identity=24.9443207126949, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24664379, Length=449, Percent_Identity=24.9443207126949, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24651635, Length=429, Percent_Identity=25.6410256410256, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24651633, Length=429, Percent_Identity=25.6410256410256, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI45550968, Length=480, Percent_Identity=23.75, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19921172, Length=480, Percent_Identity=23.75, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641995, Length=406, Percent_Identity=25.8620689655172, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641993, Length=406, Percent_Identity=25.8620689655172, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49423; Mature: 49291

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SLFRKKNVDRMIAGAQAAGLKKALGAVDLTFLGIGAIIGTGIFVLTGTGAVQAGPALML
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHCCHHHHH
SFVIAAIACGLAALSYAEFASTIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLAASAV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVGWSGYLQSLLQGFGVSLPTALTAAPGALPGVVTYFNLPAFVVMLVITTLLSIGIREST
HHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RVNNIMVFIKVAVVLLVIAVGVFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAEEVKNPKRDLPVGIIASLGVCAFLYVAVAAIATGIVPWAQYANVSHPISYALQVAGEK
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHH
WVAGFIDLGAVIGMLTVILVMSYGQTRIIFAMSRDGLLPAALSRVHPRFATPFLTTWLVG
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHCCCHHCHHHHHHHHHH
LFFGLIAALIPLNVLAELINIGTLAAFSMVSIAVLVLRRTHPDLPRAFRCPGVPLVPILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
VAACLFLMLNLQPVTWIAFLTWLVIGLFVYFAYSRSRSKLAHGAQQH
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-tryptophan [Periplasm]; Proton [Periplasm]; Proton [Periplasm]; L-tyrosine [Periplasm]; Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: L-tryptophan [Periplasm] + Proton [Periplasm] = L-tryptophan [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] +

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]