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The map label for this gene is yccK [H]

Identifier: 52843016

GI number: 52843016

Start: 3182643

End: 3183653

Strand: Direct

Name: yccK [H]

Synonym: lpg2820

Alternate gene names: 52843016

Gene position: 3182643-3183653 (Clockwise)

Preceding gene: 52843013

Following gene: 52843017

Centisome position: 93.67

GC content: 39.37

Gene sequence:

>1011_bases
ATGAAATATCGCAAATTGGGAAAGGTGGGGCCTGATGTCTCAGCATTGGGCTTTGGGTGCATGGGATTATCAGAGTTTTA
TGGCAAACCCGCTCGCCTTGATGATGCAATCAAAATTATTCGTAATGCGCATGACCAATACCAAGTTAATTTCTTTGATA
CAGCTGATATTTATGGAAAAGGTAAAAATGAAGAATTAGTTGGTAAAGCGATAAAACCCTTTCGTAACCAGATTATACTT
GCAACGAAATGCGGAGTAGTAAGGACAGGCTCTAATGATGAAATGAGTGTCAATAATTCATCTGCTTATATCAGAACAGC
CTGTGAGAAAAGCCTAAAACGCTTAAATACTGACCACATTGATCTCTACTATTTGCATCGTTATGACCATCAAACACCAA
TTGAAGAAGTGATGGAGATAATGCATGACCTTATTGATGAAGGCAAAATTGGTTATATTGGTTTATCTGAAACTGATGCT
GATACCATTCGGGCAGCTTATACAGCAGTCAAGGACAAACTGGTTGCTGTTCAAACTGAATATTCACTTCGAGTTCGAGC
TCCGGCGACAGCAGTTTTGGGCACCTGCCGTGAATTGGGTATTTGTTTTGTTGCCTACTGCCCCATAGCACGTGGTTTCC
TCAGTGGAAAAATTAAGAAGCCCAATCTTTTAAGGACAAATGGCTTTGATTTCAGAACTAATATTCCGCAATTCCAACCT
GAAAACTTTGATCAAAATCTTGGCTTAGTCAATGAACTTGAGACCATAGGAGAAAAAACAGGCTACACCCCGGCACAATT
ATCATTAGCTTGGCTATTGGCTCAAGGAGAAGACATTATCCCCATTCCCGGAACCTCGAATCCACAACACTTAGCAGAAA
ATATGCGCTCAATTGATATTTTTCTAACTCCTGAACAAATGAAAGATTTGGAAAATGCTTACAAAAATAATCCTGTTGCC
GGGAAACGATTATCTAAGGAACTGATGGCAACCTTTCATTTAAAAGAATAA

Upstream 100 bases:

>100_bases
CATTTCAGAAATAAAATCACAATCATTAATATGTTACTGCCAAATAATTCTATACTTTATTCAACTGTCCAAATAAAACC
ATGTCAGTTGAGGATAAACC

Downstream 100 bases:

>100_bases
GCTGTATGTGAATAGCATAGGAGAATGACGCTTTCTTAACCGCAAATCAGGAAACTTTCCAACATTCTAAAAACCATGTT
TACAAAAGTTAGAAAAGATT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKYRKLGKVGPDVSALGFGCMGLSEFYGKPARLDDAIKIIRNAHDQYQVNFFDTADIYGKGKNEELVGKAIKPFRNQIIL
ATKCGVVRTGSNDEMSVNNSSAYIRTACEKSLKRLNTDHIDLYYLHRYDHQTPIEEVMEIMHDLIDEGKIGYIGLSETDA
DTIRAAYTAVKDKLVAVQTEYSLRVRAPATAVLGTCRELGICFVAYCPIARGFLSGKIKKPNLLRTNGFDFRTNIPQFQP
ENFDQNLGLVNELETIGEKTGYTPAQLSLAWLLAQGEDIIPIPGTSNPQHLAENMRSIDIFLTPEQMKDLENAYKNNPVA
GKRLSKELMATFHLKE

Sequences:

>Translated_336_residues
MKYRKLGKVGPDVSALGFGCMGLSEFYGKPARLDDAIKIIRNAHDQYQVNFFDTADIYGKGKNEELVGKAIKPFRNQIIL
ATKCGVVRTGSNDEMSVNNSSAYIRTACEKSLKRLNTDHIDLYYLHRYDHQTPIEEVMEIMHDLIDEGKIGYIGLSETDA
DTIRAAYTAVKDKLVAVQTEYSLRVRAPATAVLGTCRELGICFVAYCPIARGFLSGKIKKPNLLRTNGFDFRTNIPQFQP
ENFDQNLGLVNELETIGEKTGYTPAQLSLAWLLAQGEDIIPIPGTSNPQHLAENMRSIDIFLTPEQMKDLENAYKNNPVA
GKRLSKELMATFHLKE
>Mature_336_residues
MKYRKLGKVGPDVSALGFGCMGLSEFYGKPARLDDAIKIIRNAHDQYQVNFFDTADIYGKGKNEELVGKAIKPFRNQIIL
ATKCGVVRTGSNDEMSVNNSSAYIRTACEKSLKRLNTDHIDLYYLHRYDHQTPIEEVMEIMHDLIDEGKIGYIGLSETDA
DTIRAAYTAVKDKLVAVQTEYSLRVRAPATAVLGTCRELGICFVAYCPIARGFLSGKIKKPNLLRTNGFDFRTNIPQFQP
ENFDQNLGLVNELETIGEKTGYTPAQLSLAWLLAQGEDIIPIPGTSNPQHLAENMRSIDIFLTPEQMKDLENAYKNNPVA
GKRLSKELMATFHLKE

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=334, Percent_Identity=28.7425149700599, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27436962, Length=334, Percent_Identity=28.4431137724551, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436966, Length=334, Percent_Identity=28.1437125748503, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI27436969, Length=334, Percent_Identity=27.5449101796407, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI27436971, Length=334, Percent_Identity=27.2455089820359, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI4504825, Length=332, Percent_Identity=27.4096385542169, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI223718702, Length=172, Percent_Identity=32.5581395348837, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI41327764, Length=175, Percent_Identity=32.5714285714286, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI41152114, Length=221, Percent_Identity=28.0542986425339, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87081735, Length=335, Percent_Identity=34.3283582089552, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1788070, Length=320, Percent_Identity=31.875, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789375, Length=314, Percent_Identity=27.7070063694268, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787674, Length=307, Percent_Identity=26.7100977198697, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788081, Length=267, Percent_Identity=26.9662921348315, Blast_Score=92, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6325169, Length=348, Percent_Identity=26.7241379310345, Blast_Score=112, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6323998, Length=279, Percent_Identity=27.9569892473118, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=275, Percent_Identity=27.2727272727273, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319951, Length=277, Percent_Identity=26.3537906137184, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6322615, Length=253, Percent_Identity=27.6679841897233, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6325384, Length=341, Percent_Identity=26.6862170087977, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24646155, Length=184, Percent_Identity=33.1521739130435, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24646159, Length=169, Percent_Identity=28.4023668639053, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37619; Mature: 37619

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYRKLGKVGPDVSALGFGCMGLSEFYGKPARLDDAIKIIRNAHDQYQVNFFDTADIYGK
CCCCCCCCCCCCHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEECHHHCCC
GKNEELVGKAIKPFRNQIILATKCGVVRTGSNDEMSVNNSSAYIRTACEKSLKRLNTDHI
CCCHHHHHHHHHHHHCCEEEEECCCEEECCCCCCEEECCCCHHHHHHHHHHHHHCCCCCE
DLYYLHRYDHQTPIEEVMEIMHDLIDEGKIGYIGLSETDADTIRAAYTAVKDKLVAVQTE
EEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHEEEEEEC
YSLRVRAPATAVLGTCRELGICFVAYCPIARGFLSGKIKKPNLLRTNGFDFRTNIPQFQP
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCC
ENFDQNLGLVNELETIGEKTGYTPAQLSLAWLLAQGEDIIPIPGTSNPQHLAENMRSIDI
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHEECCCCEEECCCCCCHHHHHHHHHEEEE
FLTPEQMKDLENAYKNNPVAGKRLSKELMATFHLKE
EECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKYRKLGKVGPDVSALGFGCMGLSEFYGKPARLDDAIKIIRNAHDQYQVNFFDTADIYGK
CCCCCCCCCCCCHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEECHHHCCC
GKNEELVGKAIKPFRNQIILATKCGVVRTGSNDEMSVNNSSAYIRTACEKSLKRLNTDHI
CCCHHHHHHHHHHHHCCEEEEECCCEEECCCCCCEEECCCCHHHHHHHHHHHHHCCCCCE
DLYYLHRYDHQTPIEEVMEIMHDLIDEGKIGYIGLSETDADTIRAAYTAVKDKLVAVQTE
EEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHEEEEEEC
YSLRVRAPATAVLGTCRELGICFVAYCPIARGFLSGKIKKPNLLRTNGFDFRTNIPQFQP
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCC
ENFDQNLGLVNELETIGEKTGYTPAQLSLAWLLAQGEDIIPIPGTSNPQHLAENMRSIDI
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHEECCCCEEECCCCCCHHHHHHHHHEEEE
FLTPEQMKDLENAYKNNPVAGKRLSKELMATFHLKE
EECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]