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The map label for this gene is yrfI

Identifier: 52843013

GI number: 52843013

Start: 3179864

End: 3180727

Strand: Direct

Name: yrfI

Synonym: lpg2817

Alternate gene names: 52843013

Gene position: 3179864-3180727 (Clockwise)

Preceding gene: 52843011

Following gene: 52843016

Centisome position: 93.59

GC content: 37.73

Gene sequence:

>864_bases
TTGTGTTATGAGTTTGAAATGAAAGAAGCAGATACCTTACAGCGTTTTATTTTTGAGCATGCGAATATCCGTGGCGAAAT
CGTTCATATTGAAAAAACATTTCAAAACATTATGAACCAACGTGATTACCCACCCATGGTAAAAAATCTTTTAGGTGAAG
CGTTAGTCTCATGTTTACTCCTGGCAAGCAGCATTAAATTTGAAGGAAATTTAAGTCTGCAATTTCAAGGTGACGAAAGA
TTATCCCTGTTACTCGTTCAATGTGATCATAATTTAAATATAAGAGGCTTTGCAAAATGTGCAGAGGGTCTTGAAATTGC
TGATTACGCGACCGCTTTTCTTCAAGGCCGAATGGTCATTACGCTCAGTCAAGACAACCAAACTCAAGCCTATCAAAGCC
TGATACCTATTCAATCCACGTCCATGAGCGAAAATCTGATGACTTATTTTGCCCAATCAGAGCAAATTGCTACTCGTGTT
TGGTTAGCTGTCAATGAAGACATGGCTGCAGGTATGCTATTACAACTTATGCCAGGTCAAGATACAATTCAAAGAGAACA
ATTTTGGGAGTATGCCGTTCAGCTGGGACAAACAGTAACTGAAGGTGAATTGCTGACCATAGACAATCAAACACTACTCT
ATCGTCTTTATCATGAAACGGAATTAAGAATATTCGAAAGCCGATCTACCCGTTTCCAATGCCGTTGTAATCAGGAAAAA
ATGAAACAGGTCATTACTGTACTGGGAGAAGAAGAGGCAACAGATTTAATCAAAGAAAAAGGAAAAATAGAAATCACTTG
CGATTTTTGCAATCAAAAATACACTTTTGATTCAATCGACGTGACTCTACTATTTCGCAAATAA

Upstream 100 bases:

>100_bases
GCTGGTTATGGAAACTACTATTCCTCTTGTAAGATTTTGTTCAAAATAACTGAACTCAGAAAAGGCCTGAGATAAACATT
TTATGTTAGAATAGGTCTAT

Downstream 100 bases:

>100_bases
AATGAGCCTCTGCCTACTGCATAGTCAAATCGGGTTCTGCCAGAACGCCACAACTTGACTGACTAAACTGGATATACTCT
CCTCGCATGGCTTGTAATAC

Product: heat shock protein 33, redox regulated chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33 [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MCYEFEMKEADTLQRFIFEHANIRGEIVHIEKTFQNIMNQRDYPPMVKNLLGEALVSCLLLASSIKFEGNLSLQFQGDER
LSLLLVQCDHNLNIRGFAKCAEGLEIADYATAFLQGRMVITLSQDNQTQAYQSLIPIQSTSMSENLMTYFAQSEQIATRV
WLAVNEDMAAGMLLQLMPGQDTIQREQFWEYAVQLGQTVTEGELLTIDNQTLLYRLYHETELRIFESRSTRFQCRCNQEK
MKQVITVLGEEEATDLIKEKGKIEITCDFCNQKYTFDSIDVTLLFRK

Sequences:

>Translated_287_residues
MCYEFEMKEADTLQRFIFEHANIRGEIVHIEKTFQNIMNQRDYPPMVKNLLGEALVSCLLLASSIKFEGNLSLQFQGDER
LSLLLVQCDHNLNIRGFAKCAEGLEIADYATAFLQGRMVITLSQDNQTQAYQSLIPIQSTSMSENLMTYFAQSEQIATRV
WLAVNEDMAAGMLLQLMPGQDTIQREQFWEYAVQLGQTVTEGELLTIDNQTLLYRLYHETELRIFESRSTRFQCRCNQEK
MKQVITVLGEEEATDLIKEKGKIEITCDFCNQKYTFDSIDVTLLFRK
>Mature_287_residues
MCYEFEMKEADTLQRFIFEHANIRGEIVHIEKTFQNIMNQRDYPPMVKNLLGEALVSCLLLASSIKFEGNLSLQFQGDER
LSLLLVQCDHNLNIRGFAKCAEGLEIADYATAFLQGRMVITLSQDNQTQAYQSLIPIQSTSMSENLMTYFAQSEQIATRV
WLAVNEDMAAGMLLQLMPGQDTIQREQFWEYAVQLGQTVTEGELLTIDNQTLLYRLYHETELRIFESRSTRFQCRCNQEK
MKQVITVLGEEEATDLIKEKGKIEITCDFCNQKYTFDSIDVTLLFRK

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress [H]

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family [H]

Homologues:

Organism=Escherichia coli, GI87082260, Length=280, Percent_Identity=33.9285714285714, Blast_Score=194, Evalue=6e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- InterPro:   IPR023212 [H]

Pfam domain/function: PF01430 HSP33 [H]

EC number: NA

Molecular weight: Translated: 33157; Mature: 33157

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCYEFEMKEADTLQRFIFEHANIRGEIVHIEKTFQNIMNQRDYPPMVKNLLGEALVSCLL
CCEEECCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LASSIKFEGNLSLQFQGDERLSLLLVQCDHNLNIRGFAKCAEGLEIADYATAFLQGRMVI
HHHHCEECCCEEEEECCCCCEEEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHCCCEEE
TLSQDNQTQAYQSLIPIQSTSMSENLMTYFAQSEQIATRVWLAVNEDMAAGMLLQLMPGQ
EECCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHEEEEEEEECCCHHHCEEEEECCCC
DTIQREQFWEYAVQLGQTVTEGELLTIDNQTLLYRLYHETELRIFESRSTRFQCRCNQEK
HHHHHHHHHHHHHHHCCEECCCEEEEECCCEEEEEEECCCEEEEEECCCCEEEEECCHHH
MKQVITVLGEEEATDLIKEKGKIEITCDFCNQKYTFDSIDVTLLFRK
HHHHHHHHCCHHHHHHHHCCCCEEEEEEECCCCEEECCEEEEEEEEC
>Mature Secondary Structure
MCYEFEMKEADTLQRFIFEHANIRGEIVHIEKTFQNIMNQRDYPPMVKNLLGEALVSCLL
CCEEECCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LASSIKFEGNLSLQFQGDERLSLLLVQCDHNLNIRGFAKCAEGLEIADYATAFLQGRMVI
HHHHCEECCCEEEEECCCCCEEEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHCCCEEE
TLSQDNQTQAYQSLIPIQSTSMSENLMTYFAQSEQIATRVWLAVNEDMAAGMLLQLMPGQ
EECCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHEEEEEEEECCCHHHCEEEEECCCC
DTIQREQFWEYAVQLGQTVTEGELLTIDNQTLLYRLYHETELRIFESRSTRFQCRCNQEK
HHHHHHHHHHHHHHHCCEECCCEEEEECCCEEEEEEECCCEEEEEECCCCEEEEECCHHH
MKQVITVLGEEEATDLIKEKGKIEITCDFCNQKYTFDSIDVTLLFRK
HHHHHHHHCCHHHHHHHHCCCCEEEEEEECCCCEEECCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA