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The map label for this gene is glmM

Identifier: 52842991

GI number: 52842991

Start: 3146601

End: 3147968

Strand: Reverse

Name: glmM

Synonym: lpg2794

Alternate gene names: 52842991

Gene position: 3147968-3146601 (Counterclockwise)

Preceding gene: 52842992

Following gene: 52842989

Centisome position: 92.65

GC content: 41.15

Gene sequence:

>1368_bases
ATGAGTCAACGTAAATATTTTGGTACGGATGGAATACGGGGTCACGTTGGATTATCAAATATTAACCCTGAATTTGTTTT
AAAATTAGGCTGGGCAGTAGGCTGCGTTCTTGCGAACGGAGCGAGGAAAAAGGTAGTGATTGGTAAGGACACCAGAGTGT
CTGGCTATATGTTGGAGTCGGCTTTGGAAGCAGGTTTGTCCGCAGCTGGAGTTGATGTGGCATTATTAGGACCAATGCCT
ACTCCTGGAATAGCCTATCTAACACAAACATTGAGGGCTAATGCAGGCATCGTGATTAGCGCTTCTCATAATTTATTTGA
AGACAATGGCATTAAATTTTTTTCTGCTGATGGAGGAAAACTTCCGGATAGTGTAGAGCTTGCAATTGAAGCCCAATTAG
AAAAACAGTTGCAAACTGTACCTTCAGCCAAGCTGGGTAAAGCAACACGTATTAATGATGCAGCGGGTCGTTACATAGAG
TTTTGTAAATCTACGATTCCTTCCCTATCTCGACTATCCAATTTGAAAATAGTTGTGGATTGCGCCAACGGGGCAACCTA
TCATATCGCCCCAAATGTATTCTCTGAATTGGGTGCTGATGTAGTTCCTATAGGAATTAAACCAGATGGTTTTAATATCA
ATCAAGAATGTGGTTCGACAGCGCCTGAATTATTAAGAGAAAAGGTGATTGCTGTTGGGGCTGATATTGGTATTGGTTTG
GATGGAGACGGGGATCGAGTTATTTTAGTGGATTCACTGGGAAATCTCGTAGATGGCGATCAAATTATTTATATCATTGC
CAAGGACAGACACCAACGAGGAGTACTGCATGGAGGGGTCGTAGGCACGTTGATGAGTAATTATGGTCTTGAATTAGCAA
TTACCTCATTGGGGGTTCCTTTTCAACGCTCAAAAGTAGGTGACAGGTATGTTCTTGAAACGCTAAGAGAGAAAGATTGG
AAGATTGGAGGTGAAACTTCTGGACATATTGTTTGTTTGGATAAAACAACAACAGGTGATGGAATTGTAGCAGCACTGCA
AGTTCTTTCAATCATGGTGAAGCAAAATAAAGCACTGCATGAGTTAACTGCAGGTATTCAATTGTTACCTCAAACTTTAG
TGAATTTAAAAACGAATAATGCTGCCTTGTTAGCCTCTAATCCTGATGTAATTCAGGCGGTTAAAAATTTGGAAAAACAT
CTTAATGGAGAGGGTAGAGTGTTACTCAGACCTTCTGGCACTGAGCCTTTACTGAGAGTTATGGTGGAAGGTGCTAATGC
ATCGATAGTCAAGCAACAAGCACAAATGTTATGTGATGACATCAGTCAGATCGATAAAAAAATGACTGAGAGCCTACCGT
CCACTTGA

Upstream 100 bases:

>100_bases
TAATGCAATTTATCAAGCTGCTAAAGAAATCGGTTAATAGCTCATGAAATGATCAGAAGACAACTGAGATTAGAAAAATT
AAATAATAAGGTAGGTAAGG

Downstream 100 bases:

>100_bases
GCATCTGTCTTTTTAAGTTCTAATGCAGGGGCTTTTTCAAAAGCCCCTCTGTTTCACAGTATAAGGTATTAACTACTTGT
TGGAGCCATGGAGTGGAGTA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MSQRKYFGTDGIRGHVGLSNINPEFVLKLGWAVGCVLANGARKKVVIGKDTRVSGYMLESALEAGLSAAGVDVALLGPMP
TPGIAYLTQTLRANAGIVISASHNLFEDNGIKFFSADGGKLPDSVELAIEAQLEKQLQTVPSAKLGKATRINDAAGRYIE
FCKSTIPSLSRLSNLKIVVDCANGATYHIAPNVFSELGADVVPIGIKPDGFNINQECGSTAPELLREKVIAVGADIGIGL
DGDGDRVILVDSLGNLVDGDQIIYIIAKDRHQRGVLHGGVVGTLMSNYGLELAITSLGVPFQRSKVGDRYVLETLREKDW
KIGGETSGHIVCLDKTTTGDGIVAALQVLSIMVKQNKALHELTAGIQLLPQTLVNLKTNNAALLASNPDVIQAVKNLEKH
LNGEGRVLLRPSGTEPLLRVMVEGANASIVKQQAQMLCDDISQIDKKMTESLPST

Sequences:

>Translated_455_residues
MSQRKYFGTDGIRGHVGLSNINPEFVLKLGWAVGCVLANGARKKVVIGKDTRVSGYMLESALEAGLSAAGVDVALLGPMP
TPGIAYLTQTLRANAGIVISASHNLFEDNGIKFFSADGGKLPDSVELAIEAQLEKQLQTVPSAKLGKATRINDAAGRYIE
FCKSTIPSLSRLSNLKIVVDCANGATYHIAPNVFSELGADVVPIGIKPDGFNINQECGSTAPELLREKVIAVGADIGIGL
DGDGDRVILVDSLGNLVDGDQIIYIIAKDRHQRGVLHGGVVGTLMSNYGLELAITSLGVPFQRSKVGDRYVLETLREKDW
KIGGETSGHIVCLDKTTTGDGIVAALQVLSIMVKQNKALHELTAGIQLLPQTLVNLKTNNAALLASNPDVIQAVKNLEKH
LNGEGRVLLRPSGTEPLLRVMVEGANASIVKQQAQMLCDDISQIDKKMTESLPST
>Mature_454_residues
SQRKYFGTDGIRGHVGLSNINPEFVLKLGWAVGCVLANGARKKVVIGKDTRVSGYMLESALEAGLSAAGVDVALLGPMPT
PGIAYLTQTLRANAGIVISASHNLFEDNGIKFFSADGGKLPDSVELAIEAQLEKQLQTVPSAKLGKATRINDAAGRYIEF
CKSTIPSLSRLSNLKIVVDCANGATYHIAPNVFSELGADVVPIGIKPDGFNINQECGSTAPELLREKVIAVGADIGIGLD
GDGDRVILVDSLGNLVDGDQIIYIIAKDRHQRGVLHGGVVGTLMSNYGLELAITSLGVPFQRSKVGDRYVLETLREKDWK
IGGETSGHIVCLDKTTTGDGIVAALQVLSIMVKQNKALHELTAGIQLLPQTLVNLKTNNAALLASNPDVIQAVKNLEKHL
NGEGRVLLRPSGTEPLLRVMVEGANASIVKQQAQMLCDDISQIDKKMTESLPST

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=445, Percent_Identity=61.7977528089888, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI1788361, Length=462, Percent_Identity=29.4372294372294, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_LEGPA (Q5X1A3)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_125145.1
- ProteinModelPortal:   Q5X1A3
- STRING:   Q5X1A3
- GeneID:   3118188
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp2840
- LegioList:   lpp2840
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   MIAIDEL
- ProtClustDB:   PRK10887
- BioCyc:   LPNE297246:LPP2840-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48344; Mature: 48213

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQRKYFGTDGIRGHVGLSNINPEFVLKLGWAVGCVLANGARKKVVIGKDTRVSGYMLES
CCCCCCCCCCCCCCCCCCCCCCHHHEEEEHHHHHHHEECCCCCEEEECCCCCCHHHHHHH
ALEAGLSAAGVDVALLGPMPTPGIAYLTQTLRANAGIVISASHNLFEDNGIKFFSADGGK
HHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCEECCCCEEEEECCCCC
LPDSVELAIEAQLEKQLQTVPSAKLGKATRINDAAGRYIEFCKSTIPSLSRLSNLKIVVD
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEE
CANGATYHIAPNVFSELGADVVPIGIKPDGFNINQECGSTAPELLREKVIAVGADIGIGL
CCCCCEEEECCHHHHHCCCCEEEEECCCCCCCCCHHHCCHHHHHHHHHHHHCCCCEEECC
DGDGDRVILVDSLGNLVDGDQIIYIIAKDRHQRGVLHGGVVGTLMSNYGLELAITSLGVP
CCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCC
FQRSKVGDRYVLETLREKDWKIGGETSGHIVCLDKTTTGDGIVAALQVLSIMVKQNKALH
CHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHH
ELTAGIQLLPQTLVNLKTNNAALLASNPDVIQAVKNLEKHLNGEGRVLLRPSGTEPLLRV
HHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHH
MVEGANASIVKQQAQMLCDDISQIDKKMTESLPST
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQRKYFGTDGIRGHVGLSNINPEFVLKLGWAVGCVLANGARKKVVIGKDTRVSGYMLES
CCCCCCCCCCCCCCCCCCCCCHHHEEEEHHHHHHHEECCCCCEEEECCCCCCHHHHHHH
ALEAGLSAAGVDVALLGPMPTPGIAYLTQTLRANAGIVISASHNLFEDNGIKFFSADGGK
HHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCEECCCCEEEEECCCCC
LPDSVELAIEAQLEKQLQTVPSAKLGKATRINDAAGRYIEFCKSTIPSLSRLSNLKIVVD
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEE
CANGATYHIAPNVFSELGADVVPIGIKPDGFNINQECGSTAPELLREKVIAVGADIGIGL
CCCCCEEEECCHHHHHCCCCEEEEECCCCCCCCCHHHCCHHHHHHHHHHHHCCCCEEECC
DGDGDRVILVDSLGNLVDGDQIIYIIAKDRHQRGVLHGGVVGTLMSNYGLELAITSLGVP
CCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCC
FQRSKVGDRYVLETLREKDWKIGGETSGHIVCLDKTTTGDGIVAALQVLSIMVKQNKALH
CHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHH
ELTAGIQLLPQTLVNLKTNNAALLASNPDVIQAVKNLEKHLNGEGRVLLRPSGTEPLLRV
HHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHH
MVEGANASIVKQQAQMLCDDISQIDKKMTESLPST
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA