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The map label for this gene is uhpC

Identifier: 52842761

GI number: 52842761

Start: 2885982

End: 2887349

Strand: Direct

Name: uhpC

Synonym: lpg2553

Alternate gene names: 52842761

Gene position: 2885982-2887349 (Clockwise)

Preceding gene: 52842759

Following gene: 52842762

Centisome position: 84.94

GC content: 39.69

Gene sequence:

>1368_bases
ATGGCATTATTGAGTTTTCTAAAACCTGCTCCATATCTTGATGAAATTCAGGATAAAAACGTTGTTAAACGGCAATATCG
TTATTGGCGTATTCGCACCTTTTATGCAATGTATATAGGGTATGCGTTGTTTTATTTTACGCGAAAGAGTTTTACCTTCG
TGATGCCTGCGTTACAAAGCACCTTGGGGATGACTAAAACTGAACTGGGAATGATCGCCAGCATTTTGAGTTTAAGTTAT
GGTATCAGCAAATTTTTGAGTGGAATTCTTGGTGATAAATCTAATCCTCGTTATTTAATGGCGATCGGACTGATTTTGAC
AGGTGTTTTTAATATTTTGTTTGGATTGTCTTCTACCTGGTGGTTATTCGCTATTTTTTGGGGATTGAATGGTTGGTTTC
AAGGGTGGGGCTGGCCAGGATGTACTAAATTATTAACACATTGGTATTCTCAATCGGAGCGTGGCCGTTGGTGGAGTCTT
TGGAATACATCACACAACGTTGGTGGTGCATTAATTCCTTTGATTGTTGCTGTGTGCGCGCAATACTTCGGCTGGCGTTC
AGCCATGTTTGTGCCTGGGATCATTTGCATTTTAGGAGGTGTTTTTTTAATCAATCGTTTAAGAGATACCCCACAATCAC
TTGGTTTACCCGCGATAGAGCAATATCATGAAGATTTTTCTGGTTCCACAAATCACCACCAGGAGAAAACAGAACTCTCA
GTCAAAGAAATTCTTTGGAATTATGTGTTGTGCAACCAATATATTTGGATACTGTCCATTTCTTATTTGTTTATTTACAT
TGTCCGAACGGCCATTAATGATTGGAGCATGTTGTATTTAACGGAAGTGAAAGAGTATTCCTTAATCACTGCAGGCAGTT
GTGTCATATGGTTTGAAGTTGGTGGCTTTTTTGGAAATCTGGTTGCCGGCTGGTCTTCTGATAAAATATTTCAAGGTAAA
CGCAATCCAATCAACGTTCTTTTTACTGCAGGCGTATTTGCCACTTTATTGCTGTTTACGTTAACCAGGGCATATACACC
GTTCCTCGATGCTTTGTTTCTTTTTTTCTTTGGTTTTTTTATCTTTGGACCACAAATGATGATCGGTATGGCCTGTGCGG
AATTAGCACATAAAAAAGCAGCGGCGACTGCAACTGGCTTTGCCGGATTTTTTGCTTATTGTTTAGGTGCTGTTCTGGCC
GGTGCTCCTTTGGGTGCAATTATCAAAAATTACGGCTGGGATAATTTCTTCCTCACATTGTTTGTTTGCTGCTTGATTCC
ATTACTTTTGATGCTGCCGCTCTGGCATGTGAAAGTTAATCCAAAGTATCGTCAATCAGAATTTTCAGGCAAATCCGAAT
TTGCTTAG

Upstream 100 bases:

>100_bases
ATCATCAATAGGTATGATCCTGTTAAATTTTCACTAGAAAGATTTGACATACTTTGCGAGTTACATTCTAATCATGTTTT
TTTCATGATCATGGACAATC

Downstream 100 bases:

>100_bases
TGATTGGCTTCCCAGGGTAATCCAGAAAAAGTAGGTCGGACCTGCCTTGGCCCGACCTGCTCTTGCTACCTCCACATGAA
TGCCCCTGGGGTATAGAGAT

Product: hexosephosphate transport

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MALLSFLKPAPYLDEIQDKNVVKRQYRYWRIRTFYAMYIGYALFYFTRKSFTFVMPALQSTLGMTKTELGMIASILSLSY
GISKFLSGILGDKSNPRYLMAIGLILTGVFNILFGLSSTWWLFAIFWGLNGWFQGWGWPGCTKLLTHWYSQSERGRWWSL
WNTSHNVGGALIPLIVAVCAQYFGWRSAMFVPGIICILGGVFLINRLRDTPQSLGLPAIEQYHEDFSGSTNHHQEKTELS
VKEILWNYVLCNQYIWILSISYLFIYIVRTAINDWSMLYLTEVKEYSLITAGSCVIWFEVGGFFGNLVAGWSSDKIFQGK
RNPINVLFTAGVFATLLLFTLTRAYTPFLDALFLFFFGFFIFGPQMMIGMACAELAHKKAAATATGFAGFFAYCLGAVLA
GAPLGAIIKNYGWDNFFLTLFVCCLIPLLLMLPLWHVKVNPKYRQSEFSGKSEFA

Sequences:

>Translated_455_residues
MALLSFLKPAPYLDEIQDKNVVKRQYRYWRIRTFYAMYIGYALFYFTRKSFTFVMPALQSTLGMTKTELGMIASILSLSY
GISKFLSGILGDKSNPRYLMAIGLILTGVFNILFGLSSTWWLFAIFWGLNGWFQGWGWPGCTKLLTHWYSQSERGRWWSL
WNTSHNVGGALIPLIVAVCAQYFGWRSAMFVPGIICILGGVFLINRLRDTPQSLGLPAIEQYHEDFSGSTNHHQEKTELS
VKEILWNYVLCNQYIWILSISYLFIYIVRTAINDWSMLYLTEVKEYSLITAGSCVIWFEVGGFFGNLVAGWSSDKIFQGK
RNPINVLFTAGVFATLLLFTLTRAYTPFLDALFLFFFGFFIFGPQMMIGMACAELAHKKAAATATGFAGFFAYCLGAVLA
GAPLGAIIKNYGWDNFFLTLFVCCLIPLLLMLPLWHVKVNPKYRQSEFSGKSEFA
>Mature_454_residues
ALLSFLKPAPYLDEIQDKNVVKRQYRYWRIRTFYAMYIGYALFYFTRKSFTFVMPALQSTLGMTKTELGMIASILSLSYG
ISKFLSGILGDKSNPRYLMAIGLILTGVFNILFGLSSTWWLFAIFWGLNGWFQGWGWPGCTKLLTHWYSQSERGRWWSLW
NTSHNVGGALIPLIVAVCAQYFGWRSAMFVPGIICILGGVFLINRLRDTPQSLGLPAIEQYHEDFSGSTNHHQEKTELSV
KEILWNYVLCNQYIWILSISYLFIYIVRTAINDWSMLYLTEVKEYSLITAGSCVIWFEVGGFFGNLVAGWSSDKIFQGKR
NPINVLFTAGVFATLLLFTLTRAYTPFLDALFLFFFGFFIFGPQMMIGMACAELAHKKAAATATGFAGFFAYCLGAVLAG
APLGAIIKNYGWDNFFLTLFVCCLIPLLLMLPLWHVKVNPKYRQSEFSGKSEFA

Specific function: Transport protein for sugar phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=414, Percent_Identity=34.0579710144928, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI4503847, Length=414, Percent_Identity=34.0579710144928, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI256219483, Length=414, Percent_Identity=34.0579710144928, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI256219543, Length=436, Percent_Identity=31.8807339449541, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI256219564, Length=340, Percent_Identity=31.4705882352941, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI46361976, Length=451, Percent_Identity=24.6119733924612, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI38093649, Length=423, Percent_Identity=28.1323877068558, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI223717983, Length=425, Percent_Identity=28, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI14150047, Length=336, Percent_Identity=24.1071428571429, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI49619231, Length=417, Percent_Identity=24.4604316546763, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI87082310, Length=436, Percent_Identity=48.394495412844, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1788573, Length=451, Percent_Identity=37.4722838137472, Blast_Score=308, Evalue=3e-85,
Organism=Escherichia coli, GI2367259, Length=434, Percent_Identity=29.9539170506912, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI2367379, Length=430, Percent_Identity=24.6511627906977, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17561094, Length=419, Percent_Identity=25.2983293556086, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17542316, Length=448, Percent_Identity=25.2232142857143, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI133901854, Length=462, Percent_Identity=23.8095238095238, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI133901856, Length=462, Percent_Identity=23.8095238095238, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI133930953, Length=462, Percent_Identity=24.025974025974, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17564202, Length=418, Percent_Identity=21.7703349282297, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17564204, Length=317, Percent_Identity=23.0283911671924, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17539138, Length=323, Percent_Identity=24.1486068111455, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24656866, Length=480, Percent_Identity=24.7916666666667, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45550478, Length=480, Percent_Identity=24.7916666666667, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24656861, Length=480, Percent_Identity=24.7916666666667, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51707; Mature: 51576

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLSFLKPAPYLDEIQDKNVVKRQYRYWRIRTFYAMYIGYALFYFTRKSFTFVMPALQS
CCHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGMTKTELGMIASILSLSYGISKFLSGILGDKSNPRYLMAIGLILTGVFNILFGLSSTW
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHH
WLFAIFWGLNGWFQGWGWPGCTKLLTHWYSQSERGRWWSLWNTSHNVGGALIPLIVAVCA
HHHHHHHHCCHHCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHH
QYFGWRSAMFVPGIICILGGVFLINRLRDTPQSLGLPAIEQYHEDFSGSTNHHQEKTELS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHCCCCCCCCHHHHHHH
VKEILWNYVLCNQYIWILSISYLFIYIVRTAINDWSMLYLTEVKEYSLITAGSCVIWFEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCEEECCCEEEEEEH
GGFFGNLVAGWSSDKIFQGKRNPINVLFTAGVFATLLLFTLTRAYTPFLDALFLFFFGFF
HHHHHHHHHCCCCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFGPQMMIGMACAELAHKKAAATATGFAGFFAYCLGAVLAGAPLGAIIKNYGWDNFFLTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHH
FVCCLIPLLLMLPLWHVKVNPKYRQSEFSGKSEFA
HHHHHHHHHHHHHHHHEECCCCHHHHHCCCCCCCC
>Mature Secondary Structure 
ALLSFLKPAPYLDEIQDKNVVKRQYRYWRIRTFYAMYIGYALFYFTRKSFTFVMPALQS
CHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGMTKTELGMIASILSLSYGISKFLSGILGDKSNPRYLMAIGLILTGVFNILFGLSSTW
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHH
WLFAIFWGLNGWFQGWGWPGCTKLLTHWYSQSERGRWWSLWNTSHNVGGALIPLIVAVCA
HHHHHHHHCCHHCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHH
QYFGWRSAMFVPGIICILGGVFLINRLRDTPQSLGLPAIEQYHEDFSGSTNHHQEKTELS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHCCCCCCCCHHHHHHH
VKEILWNYVLCNQYIWILSISYLFIYIVRTAINDWSMLYLTEVKEYSLITAGSCVIWFEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCEEECCCEEEEEEH
GGFFGNLVAGWSSDKIFQGKRNPINVLFTAGVFATLLLFTLTRAYTPFLDALFLFFFGFF
HHHHHHHHHCCCCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFGPQMMIGMACAELAHKKAAATATGFAGFFAYCLGAVLAGAPLGAIIKNYGWDNFFLTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHH
FVCCLIPLLLMLPLWHVKVNPKYRQSEFSGKSEFA
HHHHHHHHHHHHHHHHEECCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]