Click here to switch to the map view.

The map label for this gene is yggV [C]

Identifier: 52842692

GI number: 52842692

Start: 2797458

End: 2798042

Strand: Direct

Name: yggV [C]

Synonym: lpg2484

Alternate gene names: 52842692

Gene position: 2797458-2798042 (Clockwise)

Preceding gene: 52842690

Following gene: 52842693

Centisome position: 82.33

GC content: 41.71

Gene sequence:

>585_bases
ATGAAAGAAATTATTTTGGCAACCAGTAACCCTGGAAAAATAAAAGAATTAGAACAATTACTAGCCCCCACCATATGCAT
TCCCCAAGCCGACTTGGGTATATCCGATGCGGAAGAAACAGGATTAAGTTTTATAGAGAATGCCATTCTCAAAGCCCGTC
ATGCCAGCTCATTAGCCAATAAACCAGCTTTAGCCGATGACTCGGGGCTTGTAGTCCCCTCTTTAAATGGAGAGCCGGGT
ATCTATTCAGCACGCTATGCTGGAATAAAGGCAAATGACGAAGACAATATTCAACAATTGTTAAGTAAAATGGCTGATTT
ATCCCAAGAACAAAGACAAGCCTATTTTTTTTGCGCAATAGCGCTAATGCGACATGCCAAAGATCCAACACCGCTCATTG
CCACAGGCGTATTTCATGGCCTTATTAGCGTGAAACCTTCAGGAACAAATGGCTTTGGGTATGACCCGGTATTTTATCTC
AACGAATATCAATGCACAGCCGCTGAATTACCTGCTAAAATTAAAAATAGGATTAGCCATCGCGCAAAAGCTTTAAACCA
ATTACGCGCCCTTCTTCCAGATTAA

Upstream 100 bases:

>100_bases
ATGGTTTTAAATACCAGGGAGTCTTCTTGATATTTTTTTCCAAAATTCTCATGCATAATTATCCTTTTTATGAATACTGA
ATTAATAGCATGGAATAAGA

Downstream 100 bases:

>100_bases
TATGAACAGTGAAGTAGATACTCTTTTTGCACAAGCCTATAAGCTTCAATATGAAGGCCATTTACCTCAAGCCATTAGCT
TATATGAGCAGATACTTGCC

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MKEIILATSNPGKIKELEQLLAPTICIPQADLGISDAEETGLSFIENAILKARHASSLANKPALADDSGLVVPSLNGEPG
IYSARYAGIKANDEDNIQQLLSKMADLSQEQRQAYFFCAIALMRHAKDPTPLIATGVFHGLISVKPSGTNGFGYDPVFYL
NEYQCTAAELPAKIKNRISHRAKALNQLRALLPD

Sequences:

>Translated_194_residues
MKEIILATSNPGKIKELEQLLAPTICIPQADLGISDAEETGLSFIENAILKARHASSLANKPALADDSGLVVPSLNGEPG
IYSARYAGIKANDEDNIQQLLSKMADLSQEQRQAYFFCAIALMRHAKDPTPLIATGVFHGLISVKPSGTNGFGYDPVFYL
NEYQCTAAELPAKIKNRISHRAKALNQLRALLPD
>Mature_194_residues
MKEIILATSNPGKIKELEQLLAPTICIPQADLGISDAEETGLSFIENAILKARHASSLANKPALADDSGLVVPSLNGEPG
IYSARYAGIKANDEDNIQQLLSKMADLSQEQRQAYFFCAIALMRHAKDPTPLIATGVFHGLISVKPSGTNGFGYDPVFYL
NEYQCTAAELPAKIKNRISHRAKALNQLRALLPD

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=195, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1789324, Length=190, Percent_Identity=53.1578947368421, Blast_Score=209, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17556833, Length=189, Percent_Identity=29.1005291005291, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19920712, Length=188, Percent_Identity=33.5106382978723, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21004; Mature: 21004

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIILATSNPGKIKELEQLLAPTICIPQADLGISDAEETGLSFIENAILKARHASSLAN
CCCEEEEECCCCHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
KPALADDSGLVVPSLNGEPGIYSARYAGIKANDEDNIQQLLSKMADLSQEQRQAYFFCAI
CCCCCCCCCEEEECCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALMRHAKDPTPLIATGVFHGLISVKPSGTNGFGYDPVFYLNEYQCTAAELPAKIKNRISH
HHHHHCCCCCCHHHHHHHHHHHEECCCCCCCCCCCCEEEECCCCCCHHHCCHHHHHHHHH
RAKALNQLRALLPD
HHHHHHHHHHHCCC
>Mature Secondary Structure
MKEIILATSNPGKIKELEQLLAPTICIPQADLGISDAEETGLSFIENAILKARHASSLAN
CCCEEEEECCCCHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
KPALADDSGLVVPSLNGEPGIYSARYAGIKANDEDNIQQLLSKMADLSQEQRQAYFFCAI
CCCCCCCCCEEEECCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALMRHAKDPTPLIATGVFHGLISVKPSGTNGFGYDPVFYLNEYQCTAAELPAKIKNRISH
HHHHHCCCCCCHHHHHHHHHHHEECCCCCCCCCCCCEEEECCCCCCHHHCCHHHHHHHHH
RAKALNQLRALLPD
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA