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The map label for this gene is yaeL [C]

Identifier: 52842543

GI number: 52842543

Start: 2636275

End: 2637366

Strand: Reverse

Name: yaeL [C]

Synonym: lpg2333

Alternate gene names: 52842543

Gene position: 2637366-2636275 (Counterclockwise)

Preceding gene: 52842544

Following gene: 52842541

Centisome position: 77.62

GC content: 38.64

Gene sequence:

>1092_bases
CTGGATAAGGAGTCCATTATGATTATGGCATTGGTAGCCATAATACTTACGTTAATACTGGTGATAGGTATACACGAACT
GGGGCATGCACTGGCAGCCCGCCTGTTTCAGGTCAAAATTAGTAAAATTTCCATAGGATTTGGAAAACCATTAATTCAAT
GGCAAACGCAAAGTGGTTGTAACTGGATCTGGGCAATGTGGCCTTTGGGAGGGTATGTTCAGTTACTGAATTCGCGGATT
AGTCCAGTAAAGCCACAAGAAAATGCTTATTGTTTTGATAAGAAACCAATTTGGATTCGTGTGCTGATTTTATTGTCAGG
AGCGATTGCCAACCTTATTACCGCATGGATAGCCTTGGTATTGGTTTTTTATATTGGCATTAGCTACAAACAACCTCAAA
TTCAATCGGTAAAACTGGATAGCCTTGCTGCTAAGGCGGGTATTCAAGCAGGCGATCAATGGGTTGCTATAGAGAATTAC
CCAACTGATTCCTGGCAAGGGGTAGGTATGCAATTGGTAATTCATTGGGGGCAAAAGGATGTTCACATTGTTTTAAGACA
AGGGAATCAACAATTAAAACAATTGAATCTTGATTTAAGTCAGATTGAATTTACTTCAAAAGATGGCTCTCTGCTCGAGA
GTCTAGGGATCAAACCTGATTTGTCAGCAGTTTCCAGTTTGACGCGCTATCCATCTCTACTGGCTTCAATGCAAAAAGCG
TTTGCTGAGATAATCCATACCATGTACTTTTTTATAATGATATTGAAGCAATTGTTTCTCGGGGTTATTCCTTTTTCAAT
TTTACTTGGACCGTTGGCTATTTTTTCTGTTTCTGTGGCTTCTTTAACTCAAGGCGTTATCGTTTTTTTACTATTCATTG
CTACTTTGAGTCTTGCTGTAGCTTTGGTCAATTTATTTCCTATACCTGGCCTTGATGGAGGCAGCATTTTATATTCGTTT
ATAGAGAAAATTCGTGGGAAACCTGTCTCAGTGGCTGTGGAAGTCTTGCTTCATCGCTTGATGATTATTCTATTTTGTGT
TTTGTTAGTGCATTTATTAATGAATGATTTGAATCGATATTTACACCATTGA

Upstream 100 bases:

>100_bases
AATTGGCTGGAAGAAAAGGGATTCCAATGTTGCAGCTGGTAGTTGATAATACGCACAAATAGATTATTCTTTCTGGTGTG
TTTTTAATAAGCCTCATATT

Downstream 100 bases:

>100_bases
CAGTGGACTCATAGGTACGGGCTGCCTTTTAATTTTTAGTTACAGCCCGCGCACAACAACATATATCTACTCTCTTAACT
CCAGCATTTTTTAATGTATG

Product: membrane associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MDKESIMIMALVAIILTLILVIGIHELGHALAARLFQVKISKISIGFGKPLIQWQTQSGCNWIWAMWPLGGYVQLLNSRI
SPVKPQENAYCFDKKPIWIRVLILLSGAIANLITAWIALVLVFYIGISYKQPQIQSVKLDSLAAKAGIQAGDQWVAIENY
PTDSWQGVGMQLVIHWGQKDVHIVLRQGNQQLKQLNLDLSQIEFTSKDGSLLESLGIKPDLSAVSSLTRYPSLLASMQKA
FAEIIHTMYFFIMILKQLFLGVIPFSILLGPLAIFSVSVASLTQGVIVFLLFIATLSLAVALVNLFPIPGLDGGSILYSF
IEKIRGKPVSVAVEVLLHRLMIILFCVLLVHLLMNDLNRYLHH

Sequences:

>Translated_363_residues
MDKESIMIMALVAIILTLILVIGIHELGHALAARLFQVKISKISIGFGKPLIQWQTQSGCNWIWAMWPLGGYVQLLNSRI
SPVKPQENAYCFDKKPIWIRVLILLSGAIANLITAWIALVLVFYIGISYKQPQIQSVKLDSLAAKAGIQAGDQWVAIENY
PTDSWQGVGMQLVIHWGQKDVHIVLRQGNQQLKQLNLDLSQIEFTSKDGSLLESLGIKPDLSAVSSLTRYPSLLASMQKA
FAEIIHTMYFFIMILKQLFLGVIPFSILLGPLAIFSVSVASLTQGVIVFLLFIATLSLAVALVNLFPIPGLDGGSILYSF
IEKIRGKPVSVAVEVLLHRLMIILFCVLLVHLLMNDLNRYLHH
>Mature_363_residues
MDKESIMIMALVAIILTLILVIGIHELGHALAARLFQVKISKISIGFGKPLIQWQTQSGCNWIWAMWPLGGYVQLLNSRI
SPVKPQENAYCFDKKPIWIRVLILLSGAIANLITAWIALVLVFYIGISYKQPQIQSVKLDSLAAKAGIQAGDQWVAIENY
PTDSWQGVGMQLVIHWGQKDVHIVLRQGNQQLKQLNLDLSQIEFTSKDGSLLESLGIKPDLSAVSSLTRYPSLLASMQKA
FAEIIHTMYFFIMILKQLFLGVIPFSILLGPLAIFSVSVASLTQGVIVFLLFIATLSLAVALVNLFPIPGLDGGSILYSF
IEKIRGKPVSVAVEVLLHRLMIILFCVLLVHLLMNDLNRYLHH

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=210, Percent_Identity=34.7619047619048, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 40335; Mature: 40335

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKESIMIMALVAIILTLILVIGIHELGHALAARLFQVKISKISIGFGKPLIQWQTQSGC
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCCC
NWIWAMWPLGGYVQLLNSRISPVKPQENAYCFDKKPIWIRVLILLSGAIANLITAWIALV
CEEEECCCCHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVFYIGISYKQPQIQSVKLDSLAAKAGIQAGDQWVAIENYPTDSWQGVGMQLVIHWGQKD
HHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCC
VHIVLRQGNQQLKQLNLDLSQIEFTSKDGSLLESLGIKPDLSAVSSLTRYPSLLASMQKA
EEHHHHCCHHHHHHHCCCHHHHEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
FAEIIHTMYFFIMILKQLFLGVIPFSILLGPLAIFSVSVASLTQGVIVFLLFIATLSLAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVNLFPIPGLDGGSILYSFIEKIRGKPVSVAVEVLLHRLMIILFCVLLVHLLMNDLNRY
HHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHH
HCC
>Mature Secondary Structure
MDKESIMIMALVAIILTLILVIGIHELGHALAARLFQVKISKISIGFGKPLIQWQTQSGC
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCCC
NWIWAMWPLGGYVQLLNSRISPVKPQENAYCFDKKPIWIRVLILLSGAIANLITAWIALV
CEEEECCCCHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVFYIGISYKQPQIQSVKLDSLAAKAGIQAGDQWVAIENYPTDSWQGVGMQLVIHWGQKD
HHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCC
VHIVLRQGNQQLKQLNLDLSQIEFTSKDGSLLESLGIKPDLSAVSSLTRYPSLLASMQKA
EEHHHHCCHHHHHHHCCCHHHHEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
FAEIIHTMYFFIMILKQLFLGVIPFSILLGPLAIFSVSVASLTQGVIVFLLFIATLSLAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVNLFPIPGLDGGSILYSFIEKIRGKPVSVAVEVLLHRLMIILFCVLLVHLLMNDLNRY
HHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHH
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]