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The map label for this gene is radA

Identifier: 52842536

GI number: 52842536

Start: 2630172

End: 2631524

Strand: Reverse

Name: radA

Synonym: lpg2326

Alternate gene names: 52842536

Gene position: 2631524-2630172 (Counterclockwise)

Preceding gene: 52842541

Following gene: 52842535

Centisome position: 77.45

GC content: 46.27

Gene sequence:

>1353_bases
ATGAAAGTGAAAACCCAGTTTGTTTGTAATCAATGCGCGGCCATTTTTAAACAATGGGCAGGACAATGTACTCAATGTGG
CGCCTGGAATTCCATTGTTGAAGAAGGGATTATGCCTGAAAACAAGACTTTACGAAGTGGGCAATGGGCTAATCAGCGCT
CTGTCATCACTGCTGTTGAAGACGTTGTAATGGACAAAATAGTACGTATGGATTGTGGTATATCCGAGCTCAACCGGGTT
TTGGGAGGGGGGCTGGTTTATGGCTCGGTTGTTTTGATTGGAGGGGATCCGGGGATCGGTAAATCCACCTTACTGTTGCA
AACGCTGGCTAATTTATCTATGCAAGAAACAGTATTGTATGTGACGGGGGAAGAGTCATTACAACAAGTTGCCATGCGTG
CCCAAAGATTGGGACTACCTTTGGCCGGACTGCGGCTATTGGCAGAAACTCAGGTTGAATCCATCATTGCTCAAGCCCAA
AAGGAAAAGCCGCGAATTATTGTCGTCGATTCAGTACAAACGATATTCACTGAAGCCATAAGTTCTGCTCCGGGAGGAGT
TAGTCAAGTCAGGGAATCGGCAGCACAATTGGTGCGTTATGCCAAGATGACCAATACGGCCATCTTCCTGGTAGGGCATG
TCACCAAGGAAGGAACATTAGCCGGGCCTCGGGTGTTAGAACATATGGTTGATAGTGTTCTCTATTTTGAGGGGCAAAAT
GATAGCCGCTTCAGAGTCATTCGCGCCATTAAAAATCGTTTTGGCGCTGTCAATGAATTAGGTGTATTTGCGATGACTGA
CAAAGGCCTGAAGGAGGTAGCCAACCCCTCAGCTATTTTTTTATCTCGCCAGCCCGAACCTACGCCTGGCAGTGCAGTGA
TGGTGACTTGGGAAGGATCAAGACCCATGTTGGTAGAAGTACAAGCATTGGTTGATGAGGCCCACGGTCAGCAAGCGAAA
CGCGTTACTGCGGGTCTTGAGCATAATCGCCTGGCTATCTTGTTAGCTGTTTTACACCGTCATGGAGGTATCGCTACTTA
CGATCAGGATGTTTTTATCAATGTAGTCGGGGGAGTGAAAGTGACTGAAACAGCGAGTGATTTGGCTTTGTTGGCTGCAG
TGATTTCAAGTTTACGTAATCGTATATTTGATAGTGAAACCATCATATTCGGTGAAGTGGGATTAGCGGGGGAAATCAGA
CCAGTGCAAAGTGGTCAAGAACGCATTAAGGAGGCTATAAAACATGGATTCAAGCGTGCTATAGTCCCTTTTGCCAATGC
TCCCAAACAGCAAATCGATTCCATGACGGTAGAGCCAGTTAAACATTTGCGAGATGTATTGGAGAAAATGTGA

Upstream 100 bases:

>100_bases
AGATAAGTCCTGGTTCATTTAAAAATTATTTAAGGCAAATATGTTCAGCGCGAGTTATCATAAATGTACTAAATAAAATG
CTTGAATCAAGGCAAAAATT

Downstream 100 bases:

>100_bases
GTTATCAAAAACCAATCACACCGGAATATAAAATGAATGAAGATACTATCCGTGATTTTAATCGTAATGGTGCCGTATGT
CTTCGCCAATTTTTAAATGC

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MKVKTQFVCNQCAAIFKQWAGQCTQCGAWNSIVEEGIMPENKTLRSGQWANQRSVITAVEDVVMDKIVRMDCGISELNRV
LGGGLVYGSVVLIGGDPGIGKSTLLLQTLANLSMQETVLYVTGEESLQQVAMRAQRLGLPLAGLRLLAETQVESIIAQAQ
KEKPRIIVVDSVQTIFTEAISSAPGGVSQVRESAAQLVRYAKMTNTAIFLVGHVTKEGTLAGPRVLEHMVDSVLYFEGQN
DSRFRVIRAIKNRFGAVNELGVFAMTDKGLKEVANPSAIFLSRQPEPTPGSAVMVTWEGSRPMLVEVQALVDEAHGQQAK
RVTAGLEHNRLAILLAVLHRHGGIATYDQDVFINVVGGVKVTETASDLALLAAVISSLRNRIFDSETIIFGEVGLAGEIR
PVQSGQERIKEAIKHGFKRAIVPFANAPKQQIDSMTVEPVKHLRDVLEKM

Sequences:

>Translated_450_residues
MKVKTQFVCNQCAAIFKQWAGQCTQCGAWNSIVEEGIMPENKTLRSGQWANQRSVITAVEDVVMDKIVRMDCGISELNRV
LGGGLVYGSVVLIGGDPGIGKSTLLLQTLANLSMQETVLYVTGEESLQQVAMRAQRLGLPLAGLRLLAETQVESIIAQAQ
KEKPRIIVVDSVQTIFTEAISSAPGGVSQVRESAAQLVRYAKMTNTAIFLVGHVTKEGTLAGPRVLEHMVDSVLYFEGQN
DSRFRVIRAIKNRFGAVNELGVFAMTDKGLKEVANPSAIFLSRQPEPTPGSAVMVTWEGSRPMLVEVQALVDEAHGQQAK
RVTAGLEHNRLAILLAVLHRHGGIATYDQDVFINVVGGVKVTETASDLALLAAVISSLRNRIFDSETIIFGEVGLAGEIR
PVQSGQERIKEAIKHGFKRAIVPFANAPKQQIDSMTVEPVKHLRDVLEKM
>Mature_450_residues
MKVKTQFVCNQCAAIFKQWAGQCTQCGAWNSIVEEGIMPENKTLRSGQWANQRSVITAVEDVVMDKIVRMDCGISELNRV
LGGGLVYGSVVLIGGDPGIGKSTLLLQTLANLSMQETVLYVTGEESLQQVAMRAQRLGLPLAGLRLLAETQVESIIAQAQ
KEKPRIIVVDSVQTIFTEAISSAPGGVSQVRESAAQLVRYAKMTNTAIFLVGHVTKEGTLAGPRVLEHMVDSVLYFEGQN
DSRFRVIRAIKNRFGAVNELGVFAMTDKGLKEVANPSAIFLSRQPEPTPGSAVMVTWEGSRPMLVEVQALVDEAHGQQAK
RVTAGLEHNRLAILLAVLHRHGGIATYDQDVFINVVGGVKVTETASDLALLAAVISSLRNRIFDSETIIFGEVGLAGEIR
PVQSGQERIKEAIKHGFKRAIVPFANAPKQQIDSMTVEPVKHLRDVLEKM

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=449, Percent_Identity=57.6837416481069, Blast_Score=533, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 48917; Mature: 48917

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKTQFVCNQCAAIFKQWAGQCTQCGAWNSIVEEGIMPENKTLRSGQWANQRSVITAVE
CCCCHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
DVVMDKIVRMDCGISELNRVLGGGLVYGSVVLIGGDPGIGKSTLLLQTLANLSMQETVLY
HHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEEEECCCCCCHHHHHHHHHHCCCHHHEEEE
VTGEESLQQVAMRAQRLGLPLAGLRLLAETQVESIIAQAQKEKPRIIVVDSVQTIFTEAI
EECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHH
SSAPGGVSQVRESAAQLVRYAKMTNTAIFLVGHVTKEGTLAGPRVLEHMVDSVLYFEGQN
HCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHEEEECCC
DSRFRVIRAIKNRFGAVNELGVFAMTDKGLKEVANPSAIFLSRQPEPTPGSAVMVTWEGS
CCHHHHHHHHHHHHCCHHHCCEEEECCHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCC
RPMLVEVQALVDEAHGQQAKRVTAGLEHNRLAILLAVLHRHGGIATYDQDVFINVVGGVK
CCEEEHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCEEEEEECCEE
VTETASDLALLAAVISSLRNRIFDSETIIFGEVGLAGEIRPVQSGQERIKEAIKHGFKRA
EECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IVPFANAPKQQIDSMTVEPVKHLRDVLEKM
HCCCCCCCHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVKTQFVCNQCAAIFKQWAGQCTQCGAWNSIVEEGIMPENKTLRSGQWANQRSVITAVE
CCCCHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
DVVMDKIVRMDCGISELNRVLGGGLVYGSVVLIGGDPGIGKSTLLLQTLANLSMQETVLY
HHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEEEECCCCCCHHHHHHHHHHCCCHHHEEEE
VTGEESLQQVAMRAQRLGLPLAGLRLLAETQVESIIAQAQKEKPRIIVVDSVQTIFTEAI
EECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHH
SSAPGGVSQVRESAAQLVRYAKMTNTAIFLVGHVTKEGTLAGPRVLEHMVDSVLYFEGQN
HCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHEEEECCC
DSRFRVIRAIKNRFGAVNELGVFAMTDKGLKEVANPSAIFLSRQPEPTPGSAVMVTWEGS
CCHHHHHHHHHHHHCCHHHCCEEEECCHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCC
RPMLVEVQALVDEAHGQQAKRVTAGLEHNRLAILLAVLHRHGGIATYDQDVFINVVGGVK
CCEEEHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCEEEEEECCEE
VTETASDLALLAAVISSLRNRIFDSETIIFGEVGLAGEIRPVQSGQERIKEAIKHGFKRA
EECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IVPFANAPKQQIDSMTVEPVKHLRDVLEKM
HCCCCCCCHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]