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The map label for this gene is yafC [H]

Identifier: 52842501

GI number: 52842501

Start: 2589773

End: 2590693

Strand: Direct

Name: yafC [H]

Synonym: lpg2288

Alternate gene names: 52842501

Gene position: 2589773-2590693 (Clockwise)

Preceding gene: 161723246

Following gene: 52842506

Centisome position: 76.22

GC content: 38.76

Gene sequence:

>921_bases
ATGTTACCTGATCTCAATGATTTGTATTTTTTCTATCTGGTTGTGGAGCAAAGAAGCTTTACTAAAGCAGGGCGGAGTAT
AGGTATTACAAAATCAAAAATCAGTCGACGGATTAGTGAATTAGAGTCTCGTTTAGGGGTGAGGTTATTGCATCGCTCCA
CAAGAAAACTCGCGTTGACTGATATTGGACAAATTTTTTATCAACATTGCAAAGCTATGGTTGACGAGGCTCAATCTGCG
CAAGAAGCAATTGAGTTAGTGCAGAGCAAACCACGAGGGCGTATTCGTGTCACCTGTCCTGCATTGTTTGCACAATCGAC
TTTTACCGATATTATTACCCGATTTATGCAACAATATCAGGAAGTGACTATTGTTTTAAATGCCACAGATCGCCCTGTGG
ATCTGTTCCAGGAAGGATTTGATGTCGCAATTCGTTTTCAAGCTAATACCTTTGAAGATTCAACTTTAGTCGTACGCAAA
CTGGGGCTTAGTTTTAGCTCGTTGATTGCTAGTCCCACTTATCTAAATCATCATGGAACCCCTCAAACACCACAAGATTT
GGTCAATCATGCTTGTTTTGCTAAAACACGCAATGAAGGAATGAGCCAATTTTTATTAACTCATAACGATGGTCGTCAAA
TTTCTGTGCATTTTCAGCCAATTTTAGAAAGTAACGAATGGCTGGTTCTAAAACAAGCGGCATTATCACATCTTGGAATA
ACAATGATGCCTCAAGAAATTTGTCGCAAAGAAATTGATTCTGGGTTATTAGTTCCGATATTGACAGAATGGTCTTTGCC
AAAGGCAAGCCTTTATATAATCTATCCCTCTCGTCGGGGTTTGATACCAGCCATACGATCTTTTATTGATTTTGTAGCCG
AAGAATTAATTAATAATTGTACCAACATTAGGCTTAAGTAA

Upstream 100 bases:

>100_bases
CAATAAATAATAAGATGGCTTTTATATGACTCATTGTCCTATAAATAAAACCAATAAATGCTATAATTAGCAGATAACTA
AACTTACACAAGTGTAAAAA

Downstream 100 bases:

>100_bases
TTTAAACACATCAAATTTTGGTGCCCAGGGCCGGAATCGAACCGGCATGGTGTTACCACCGAGGGATTTTAAGTCCCTTG
CGTCTACCTGTTTCGCCACC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MLPDLNDLYFFYLVVEQRSFTKAGRSIGITKSKISRRISELESRLGVRLLHRSTRKLALTDIGQIFYQHCKAMVDEAQSA
QEAIELVQSKPRGRIRVTCPALFAQSTFTDIITRFMQQYQEVTIVLNATDRPVDLFQEGFDVAIRFQANTFEDSTLVVRK
LGLSFSSLIASPTYLNHHGTPQTPQDLVNHACFAKTRNEGMSQFLLTHNDGRQISVHFQPILESNEWLVLKQAALSHLGI
TMMPQEICRKEIDSGLLVPILTEWSLPKASLYIIYPSRRGLIPAIRSFIDFVAEELINNCTNIRLK

Sequences:

>Translated_306_residues
MLPDLNDLYFFYLVVEQRSFTKAGRSIGITKSKISRRISELESRLGVRLLHRSTRKLALTDIGQIFYQHCKAMVDEAQSA
QEAIELVQSKPRGRIRVTCPALFAQSTFTDIITRFMQQYQEVTIVLNATDRPVDLFQEGFDVAIRFQANTFEDSTLVVRK
LGLSFSSLIASPTYLNHHGTPQTPQDLVNHACFAKTRNEGMSQFLLTHNDGRQISVHFQPILESNEWLVLKQAALSHLGI
TMMPQEICRKEIDSGLLVPILTEWSLPKASLYIIYPSRRGLIPAIRSFIDFVAEELINNCTNIRLK
>Mature_306_residues
MLPDLNDLYFFYLVVEQRSFTKAGRSIGITKSKISRRISELESRLGVRLLHRSTRKLALTDIGQIFYQHCKAMVDEAQSA
QEAIELVQSKPRGRIRVTCPALFAQSTFTDIITRFMQQYQEVTIVLNATDRPVDLFQEGFDVAIRFQANTFEDSTLVVRK
LGLSFSSLIASPTYLNHHGTPQTPQDLVNHACFAKTRNEGMSQFLLTHNDGRQISVHFQPILESNEWLVLKQAALSHLGI
TMMPQEICRKEIDSGLLVPILTEWSLPKASLYIIYPSRRGLIPAIRSFIDFVAEELINNCTNIRLK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=33.6769759450172, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=27.7397260273973, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=29.4915254237288, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=29.3515358361775, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI87081978, Length=306, Percent_Identity=27.4509803921569, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789440, Length=294, Percent_Identity=29.2517006802721, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=26.4604810996564, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789173, Length=292, Percent_Identity=27.0547945205479, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788706, Length=303, Percent_Identity=23.4323432343234, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787601, Length=114, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI157672245, Length=140, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788748, Length=128, Percent_Identity=32.03125, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790011, Length=280, Percent_Identity=21.0714285714286, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788481, Length=293, Percent_Identity=22.1843003412969, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87082132, Length=298, Percent_Identity=22.1476510067114, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34845; Mature: 34845

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPDLNDLYFFYLVVEQRSFTKAGRSIGITKSKISRRISELESRLGVRLLHRSTRKLALT
CCCCCHHHEEEEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIGQIFYQHCKAMVDEAQSAQEAIELVQSKPRGRIRVTCPALFAQSTFTDIITRFMQQYQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHH
EVTIVLNATDRPVDLFQEGFDVAIRFQANTFEDSTLVVRKLGLSFSSLIASPTYLNHHGT
HEEEEEECCCCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHCCCCEECCCCC
PQTPQDLVNHACFAKTRNEGMSQFLLTHNDGRQISVHFQPILESNEWLVLKQAALSHLGI
CCCHHHHHHHHHHHHHHHCCHHHEEEEECCCCEEEEEEEEEECCCCEEEEHHHHHHHCCC
TMMPQEICRKEIDSGLLVPILTEWSLPKASLYIIYPSRRGLIPAIRSFIDFVAEELINNC
CCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
TNIRLK
HCCCCC
>Mature Secondary Structure
MLPDLNDLYFFYLVVEQRSFTKAGRSIGITKSKISRRISELESRLGVRLLHRSTRKLALT
CCCCCHHHEEEEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIGQIFYQHCKAMVDEAQSAQEAIELVQSKPRGRIRVTCPALFAQSTFTDIITRFMQQYQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHH
EVTIVLNATDRPVDLFQEGFDVAIRFQANTFEDSTLVVRKLGLSFSSLIASPTYLNHHGT
HEEEEEECCCCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHCCCCEECCCCC
PQTPQDLVNHACFAKTRNEGMSQFLLTHNDGRQISVHFQPILESNEWLVLKQAALSHLGI
CCCHHHHHHHHHHHHHHHCCHHHEEEEECCCCEEEEEEEEEECCCCEEEEHHHHHHHCCC
TMMPQEICRKEIDSGLLVPILTEWSLPKASLYIIYPSRRGLIPAIRSFIDFVAEELINNC
CCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
TNIRLK
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]