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The map label for this gene is ugpQ

Identifier: 52842487

GI number: 52842487

Start: 2577145

End: 2577864

Strand: Reverse

Name: ugpQ

Synonym: lpg2274

Alternate gene names: 52842487

Gene position: 2577864-2577145 (Counterclockwise)

Preceding gene: 52842488

Following gene: 52842486

Centisome position: 75.87

GC content: 40.56

Gene sequence:

>720_bases
TTGATCCTTGAAAAAATTATCGGTCACCGGGGAGCATCGGGTTATGCTCCAGAAAATACGATGGCGTCTTTTAATAAAGC
ATTGTCTTTAGGTTGTCGTTTCATTGAGTTTGATGTGATGTGCAGTCTTGATGGTGAACCTTTTATCATTCACGATGACA
ATTTGAAACGAACCACGAATGGAAAAGGAGAGGTGGGACTGATGGAGGCAGATTATCTCCGTGGTCTTGATGCTGGCTCT
TGGTATTCGAAGCAGTATAAGGGAGAAAAAATTCCACACTTTACTGACGTATTAAAGTGGTTGTCTTTTTCCGATGTTCA
GGCGAACATAGAAATAAAACCTTATCCTGGAACGGTTGAGCAAACTACTGTATCAGTGCTAAGTCATATCCATCGGCATT
GGCCCCAAAATAAAGAATTACCTCTCGTTTCCTGTTTTGAATGGGATGCTTTGGTATTATGCCGCAGTATTGCTCCAGAA
ATGCCTTTAGGGCTCTTGCTGCATGAGTGGGATAAAGATTGGTTACAGAAGGCGAAGCAATTGGAATGTTATTCAATACA
TTTCAATAGAAAGATATTAACCGCTGATCGAGTGAAGGCAGTTAAGGATCAAGGCTATGTAGTATGCGCCTATACTGTAA
ACCGTAAACGTTTGGCCAAAAAGTTATTTGATTGGGGTGTTGATGCTCTCTTTAGTGATTATCCAGACTTGTTAAAATGA

Upstream 100 bases:

>100_bases
GCGATGGCTGCTGCTCCGGCACCATTGACAGTGAGTAATGAATTAATATTGACCGCTATGGTAGAAGCAGCATCCAATCG
CAAACAGGGAGATTAATTAG

Downstream 100 bases:

>100_bases
AAATACTCTTTTTGCTTTTGTTAATTTTTCTGAGTGTCATTCCTGCTCAGGCCAAACCAGTTGAGCTGGTTTTTTGGCAT
GCGATGGCAGGGCATTTGGG

Product: glycerophosphoryl diester esterase

Products: NA

Alternate protein names: Glycerophosphodiester phosphodiesterase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MILEKIIGHRGASGYAPENTMASFNKALSLGCRFIEFDVMCSLDGEPFIIHDDNLKRTTNGKGEVGLMEADYLRGLDAGS
WYSKQYKGEKIPHFTDVLKWLSFSDVQANIEIKPYPGTVEQTTVSVLSHIHRHWPQNKELPLVSCFEWDALVLCRSIAPE
MPLGLLLHEWDKDWLQKAKQLECYSIHFNRKILTADRVKAVKDQGYVVCAYTVNRKRLAKKLFDWGVDALFSDYPDLLK

Sequences:

>Translated_239_residues
MILEKIIGHRGASGYAPENTMASFNKALSLGCRFIEFDVMCSLDGEPFIIHDDNLKRTTNGKGEVGLMEADYLRGLDAGS
WYSKQYKGEKIPHFTDVLKWLSFSDVQANIEIKPYPGTVEQTTVSVLSHIHRHWPQNKELPLVSCFEWDALVLCRSIAPE
MPLGLLLHEWDKDWLQKAKQLECYSIHFNRKILTADRVKAVKDQGYVVCAYTVNRKRLAKKLFDWGVDALFSDYPDLLK
>Mature_239_residues
MILEKIIGHRGASGYAPENTMASFNKALSLGCRFIEFDVMCSLDGEPFIIHDDNLKRTTNGKGEVGLMEADYLRGLDAGS
WYSKQYKGEKIPHFTDVLKWLSFSDVQANIEIKPYPGTVEQTTVSVLSHIHRHWPQNKELPLVSCFEWDALVLCRSIAPE
MPLGLLLHEWDKDWLQKAKQLECYSIHFNRKILTADRVKAVKDQGYVVCAYTVNRKRLAKKLFDWGVDALFSDYPDLLK

Specific function: Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols [H]

COG id: COG0584

COG function: function code C; Glycerophosphoryl diester phosphodiesterase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycerophosphoryl diester phosphodiesterase family [H]

Homologues:

Organism=Homo sapiens, GI33457301, Length=88, Percent_Identity=45.4545454545455, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI284055245, Length=85, Percent_Identity=42.3529411764706, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI284055240, Length=85, Percent_Identity=42.3529411764706, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI284055242, Length=85, Percent_Identity=42.3529411764706, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI21361649, Length=85, Percent_Identity=42.3529411764706, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI189571657, Length=87, Percent_Identity=41.3793103448276, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789858, Length=234, Percent_Identity=44.017094017094, Blast_Score=192, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17542344, Length=119, Percent_Identity=34.453781512605, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004129
- InterPro:   IPR017946 [H]

Pfam domain/function: PF03009 GDPD [H]

EC number: =3.1.4.46 [H]

Molecular weight: Translated: 27369; Mature: 27369

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS50007 PIPLC_X_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILEKIIGHRGASGYAPENTMASFNKALSLGCRFIEFDVMCSLDGEPFIIHDDNLKRTTN
CCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEEEECCCCEEEEECCCCCCCCC
GKGEVGLMEADYLRGLDAGSWYSKQYKGEKIPHFTDVLKWLSFSDVQANIEIKPYPGTVE
CCCCEEEEEHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCHH
QTTVSVLSHIHRHWPQNKELPLVSCFEWDALVLCRSIAPEMPLGLLLHEWDKDWLQKAKQ
HHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHC
LECYSIHFNRKILTADRVKAVKDQGYVVCAYTVNRKRLAKKLFDWGVDALFSDYPDLLK
CEEEEEEECCEEECHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCHHHHHHCCHHHCC
>Mature Secondary Structure
MILEKIIGHRGASGYAPENTMASFNKALSLGCRFIEFDVMCSLDGEPFIIHDDNLKRTTN
CCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEEEECCCCEEEEECCCCCCCCC
GKGEVGLMEADYLRGLDAGSWYSKQYKGEKIPHFTDVLKWLSFSDVQANIEIKPYPGTVE
CCCCEEEEEHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCHH
QTTVSVLSHIHRHWPQNKELPLVSCFEWDALVLCRSIAPEMPLGLLLHEWDKDWLQKAKQ
HHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHC
LECYSIHFNRKILTADRVKAVKDQGYVVCAYTVNRKRLAKKLFDWGVDALFSDYPDLLK
CEEEEEEECCEEECHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2541415; 1851953; 8041620; 9278503; 3062310 [H]