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The map label for this gene is pdxH [H]

Identifier: 52842353

GI number: 52842353

Start: 2387133

End: 2387723

Strand: Reverse

Name: pdxH [H]

Synonym: lpg2139

Alternate gene names: 52842353

Gene position: 2387723-2387133 (Counterclockwise)

Preceding gene: 52842354

Following gene: 52842351

Centisome position: 70.27

GC content: 38.92

Gene sequence:

>591_bases
ATGGTGGCCATGAACAATCCCATTAGCCTTTTAACAACATGGATTTCTGAGGAATTGGAAAAAGGAGCACCTAATCCACA
GCATGCCATATTATCTACAGCAGGCAAAAACTCTATTCCCCATGGGCGTGTTATCGCCATTCGCGAAATCAACGAGCAAG
GTTTATTATTTTTTACCCAACGAGGAACCAGAAAAGTTGAAGAAATGACCCATAACCCTATGGTATCTCTCACTTTTTGG
TTTGAGTTATGTGAAAGAGAGGTCATGATAGACGGTTCAGCCAGGCCATTATCGGAAAGCGAAAATCAAGCATACTGGGA
TACCTATCCGCCTTTCGCGCAAATCAGATTTCATAGTTATGCGCCTACTTCCTCACAAGTTATACCCAGCAAACAACTCA
TTGAAAATAAAAGAAAAATATTGACTTCTCAGTTTCACGATAAGCCATTGCCTATGAGTGAATATTATTATGGTTTCAGA
GTCATTCCCACACGCATGGTTTTTTATACTTATAGAACGGATGAATTGTCTGATGTCGTAGAATATTGTTTTATAAAAAA
CAATTGGGAGAAGAATCTGCTTTCTCCTTAA

Upstream 100 bases:

>100_bases
ACTGCGGGTGAATTATGGCTCACAATACTCAGCGTCGCAATGAGCTGTTGTTAATCAGTATCATTATGAACATCAAAAAA
TATTTGCAATAGGTATTCAA

Downstream 100 bases:

>100_bases
TATCAATTTGTTTAAGCCTCATGATTGACGCAACAATATTTTTTTATTACATCCAATACCCATTGCAGCGGTTTATGATT
TGATAATCGTTTATGATAGT

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MVAMNNPISLLTTWISEELEKGAPNPQHAILSTAGKNSIPHGRVIAIREINEQGLLFFTQRGTRKVEEMTHNPMVSLTFW
FELCEREVMIDGSARPLSESENQAYWDTYPPFAQIRFHSYAPTSSQVIPSKQLIENKRKILTSQFHDKPLPMSEYYYGFR
VIPTRMVFYTYRTDELSDVVEYCFIKNNWEKNLLSP

Sequences:

>Translated_196_residues
MVAMNNPISLLTTWISEELEKGAPNPQHAILSTAGKNSIPHGRVIAIREINEQGLLFFTQRGTRKVEEMTHNPMVSLTFW
FELCEREVMIDGSARPLSESENQAYWDTYPPFAQIRFHSYAPTSSQVIPSKQLIENKRKILTSQFHDKPLPMSEYYYGFR
VIPTRMVFYTYRTDELSDVVEYCFIKNNWEKNLLSP
>Mature_196_residues
MVAMNNPISLLTTWISEELEKGAPNPQHAILSTAGKNSIPHGRVIAIREINEQGLLFFTQRGTRKVEEMTHNPMVSLTFW
FELCEREVMIDGSARPLSESENQAYWDTYPPFAQIRFHSYAPTSSQVIPSKQLIENKRKILTSQFHDKPLPMSEYYYGFR
VIPTRMVFYTYRTDELSDVVEYCFIKNNWEKNLLSP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=178, Percent_Identity=26.4044943820225, Blast_Score=85, Evalue=5e-17,
Organism=Escherichia coli, GI1787926, Length=191, Percent_Identity=27.7486910994764, Blast_Score=99, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17553712, Length=173, Percent_Identity=26.5895953757225, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319509, Length=200, Percent_Identity=25, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24644901, Length=185, Percent_Identity=27.5675675675676, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45551845, Length=185, Percent_Identity=27.5675675675676, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 22815; Mature: 22815

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAMNNPISLLTTWISEELEKGAPNPQHAILSTAGKNSIPHGRVIAIREINEQGLLFFTQ
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCCCCCCCEEEEEEECCCCEEEEEC
RGTRKVEEMTHNPMVSLTFWFELCEREVMIDGSARPLSESENQAYWDTYPPFAQIRFHSY
CCCHHHHHHHCCCEEHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECC
APTSSQVIPSKQLIENKRKILTSQFHDKPLPMSEYYYGFRVIPTRMVFYTYRTDELSDVV
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEEEEEEEEECCHHHHHHH
EYCFIKNNWEKNLLSP
HHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVAMNNPISLLTTWISEELEKGAPNPQHAILSTAGKNSIPHGRVIAIREINEQGLLFFTQ
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCCCCCCCEEEEEEECCCCEEEEEC
RGTRKVEEMTHNPMVSLTFWFELCEREVMIDGSARPLSESENQAYWDTYPPFAQIRFHSY
CCCHHHHHHHCCCEEHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECC
APTSSQVIPSKQLIENKRKILTSQFHDKPLPMSEYYYGFRVIPTRMVFYTYRTDELSDVV
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEEEEEEEEECCHHHHHHH
EYCFIKNNWEKNLLSP
HHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA