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The map label for this gene is recG

Identifier: 52842250

GI number: 52842250

Start: 2276012

End: 2278084

Strand: Direct

Name: recG

Synonym: lpg2033

Alternate gene names: 52842250

Gene position: 2276012-2278084 (Clockwise)

Preceding gene: 52842246

Following gene: 52842251

Centisome position: 66.99

GC content: 41.2

Gene sequence:

>2073_bases
GTGCTGAGTAACTCTTGTGAATATTTAACTGGCGTCGGCCCAACCATTGCAGCAAAACTTGCTAAATGTGGGATTTTCAC
GATACAAGACTTGCTTTTCCACCTGCCTTATAAATACCAGGACAGAACCAGGATAACACCAATTCAGGATTTGCGCTCGA
ATGAATGGTGCGTTATCGCGGGGCATGTATACAAAACTGAAATAAAATACGGCAAAAGGATGATGTTGAATTGTTATGTG
GAAGATAAAACAGGAGTAGTGAAGCTTCGTTTTTTTCATTTCAACAAGCAGCAAATCCAGGCTTTGAATAATAGCACCAT
GATTCGAGCTTTTGGCGAAGTCCGCGGATTTAACAACCACTTGGAGATGATTCATCCAGAATATCAATTAATTGATCAAG
AATCAGATTTCCACGTGGAAGAAACTCTTACGCCAATTTATCCATCGACTCAAGGCTTGACTCAAACCCGATTAAGGCAG
TTAGTTAAAATAGCCCTGGAACAATCTGAACACGAACTTCATCAATTGGAATGGATGAGTGAAAAACAATTACAGGAAAA
CAATTTTTATGATTTGGGCGAAGCCATTAAATTACTACATAACCCTCCGCCAGATATCTCCCTCTCCAACCTCGAAGCTG
GCGAACATCCTGCTCTCAAGCGATTAATATTTGATGAATTACTGGCACAACAGCTCAGTATGCAATTTGCAAGGCAGTCA
CGCAGCAAGCTCCAGGCTCCCGCTATACTTTTCGATAATGCAATTCATAAACGTTTTATCGAATCATTGCCATTCAGTCT
TACAAACGCACAACAACGGGTTTTTAAAGAAATCAGCTTTGATTTAACTCAAAGCAAACCCATGCTTCGTTTGCTGCAAG
GAGATGTTGGGGCGGGTAAAACCATTATCGCGGCACTAGCCGCCCTTCAAGCCATTTCACAAGGATTTCAGGTTGCTTTT
ATGGCACCAACCGATTTATTAAGTGAACAACATACAAATAGCCTTAGTAAATGGTTAGAACCTATCGGTATTAATGTATT
AAGACTGAGCGGTAAAATGAAAACCACAGAACGAAAAAATGCGCTTGCAGCCCTGCAGGACAATAGCTGTCAGCTCATTG
TTGGAACTCATGCCTTATTTCAGGAGCAAGTCGAATTCGCTCGTTTGGGTTTGGTCATTATTGACGAACAACACCGATTT
GGAGTAGAACAACGGCTCCTTCTGCAACAAAAAGGGCAATTAAACCAATTAATCCCTCATCAATTATTAATGACAGCCAC
CCCTATTCCAAGAACCCTGTCAATGTCCCATTTTGCCCATTTGGATATATCGGTCATCGATGAACTACCGCCTGGCCGTA
TGCCAATTACAACAGCAGTATTAAACCAGGATAAGCGTGAACTCATTATCGAACGTTTGCAAGCGGCAATCGCCAACGGC
AAACAAGCTTACTGGGTCTGTACCCTTATAGAAGAATCTGAAAAATTACAATGCATGGCAGCAACAGATACCTCAAAAAA
ACTACAAGAACAGCTCTCTTTCGCGCGTGTTGGTCTTGTTCATGGGAGAATGAAAGCACTTGAAAAAGAAGCTACTATGG
CAGCCTTTAAACAAGGCGAGATTGATTTATTGGTGGCAACTACTGTTATTGAAGTTGGTGTAGATGTTCCTAATGCCAGT
TTAATGATCATTGAAAATGCAGAGCGACTTGGTTTGTCGCAGTTACATCAATTACGAGGGCGCGTGGGCAGAGGTAATAA
TCAATCTCATTGTCTATTACTTTATCAATCTCCTCTATCACAACAAGGTGCTGAACGTCTCAAGATCATGCGTTCAACAA
CAGACGGTTTTCTAATCTCCGAAAAGGATCTGGAGTTAAGAGGCTCAGGAGAAATATTAGGAACCAGACAGACTGGCTTT
AGACAATTTAAAATAGCTAACTTACAACGCGATAAAACCCTCTTCGCTATTTTACGTCCAATTGCAAAACAACTGGTGCT
GGAAAAAACAGCAATCGCCAGACAAATTACACAACGATGGCTGGGCAATTTTGAACAATTTTTGCAAAGTTAA

Upstream 100 bases:

>100_bases
TAACTTAGTAATGATTTGGGCAAAATTGCCAGAATGATGACTCAAGTCGCAACGAATATATTTTCCTGTTATTATTAAAT
TTTTAATCTTAAATAATACC

Downstream 100 bases:

>100_bases
AAAAATAATTAAAATTATTGAAGTCAAGACTGTTTTTTATTTTTTTCTTTGCTAACATAAGCGGTCCACAAGTAACATTC
ATTCCGTCTTATCCCTGTGG

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 690; Mature: 690

Protein sequence:

>690_residues
MLSNSCEYLTGVGPTIAAKLAKCGIFTIQDLLFHLPYKYQDRTRITPIQDLRSNEWCVIAGHVYKTEIKYGKRMMLNCYV
EDKTGVVKLRFFHFNKQQIQALNNSTMIRAFGEVRGFNNHLEMIHPEYQLIDQESDFHVEETLTPIYPSTQGLTQTRLRQ
LVKIALEQSEHELHQLEWMSEKQLQENNFYDLGEAIKLLHNPPPDISLSNLEAGEHPALKRLIFDELLAQQLSMQFARQS
RSKLQAPAILFDNAIHKRFIESLPFSLTNAQQRVFKEISFDLTQSKPMLRLLQGDVGAGKTIIAALAALQAISQGFQVAF
MAPTDLLSEQHTNSLSKWLEPIGINVLRLSGKMKTTERKNALAALQDNSCQLIVGTHALFQEQVEFARLGLVIIDEQHRF
GVEQRLLLQQKGQLNQLIPHQLLMTATPIPRTLSMSHFAHLDISVIDELPPGRMPITTAVLNQDKRELIIERLQAAIANG
KQAYWVCTLIEESEKLQCMAATDTSKKLQEQLSFARVGLVHGRMKALEKEATMAAFKQGEIDLLVATTVIEVGVDVPNAS
LMIIENAERLGLSQLHQLRGRVGRGNNQSHCLLLYQSPLSQQGAERLKIMRSTTDGFLISEKDLELRGSGEILGTRQTGF
RQFKIANLQRDKTLFAILRPIAKQLVLEKTAIARQITQRWLGNFEQFLQS

Sequences:

>Translated_690_residues
MLSNSCEYLTGVGPTIAAKLAKCGIFTIQDLLFHLPYKYQDRTRITPIQDLRSNEWCVIAGHVYKTEIKYGKRMMLNCYV
EDKTGVVKLRFFHFNKQQIQALNNSTMIRAFGEVRGFNNHLEMIHPEYQLIDQESDFHVEETLTPIYPSTQGLTQTRLRQ
LVKIALEQSEHELHQLEWMSEKQLQENNFYDLGEAIKLLHNPPPDISLSNLEAGEHPALKRLIFDELLAQQLSMQFARQS
RSKLQAPAILFDNAIHKRFIESLPFSLTNAQQRVFKEISFDLTQSKPMLRLLQGDVGAGKTIIAALAALQAISQGFQVAF
MAPTDLLSEQHTNSLSKWLEPIGINVLRLSGKMKTTERKNALAALQDNSCQLIVGTHALFQEQVEFARLGLVIIDEQHRF
GVEQRLLLQQKGQLNQLIPHQLLMTATPIPRTLSMSHFAHLDISVIDELPPGRMPITTAVLNQDKRELIIERLQAAIANG
KQAYWVCTLIEESEKLQCMAATDTSKKLQEQLSFARVGLVHGRMKALEKEATMAAFKQGEIDLLVATTVIEVGVDVPNAS
LMIIENAERLGLSQLHQLRGRVGRGNNQSHCLLLYQSPLSQQGAERLKIMRSTTDGFLISEKDLELRGSGEILGTRQTGF
RQFKIANLQRDKTLFAILRPIAKQLVLEKTAIARQITQRWLGNFEQFLQS
>Mature_690_residues
MLSNSCEYLTGVGPTIAAKLAKCGIFTIQDLLFHLPYKYQDRTRITPIQDLRSNEWCVIAGHVYKTEIKYGKRMMLNCYV
EDKTGVVKLRFFHFNKQQIQALNNSTMIRAFGEVRGFNNHLEMIHPEYQLIDQESDFHVEETLTPIYPSTQGLTQTRLRQ
LVKIALEQSEHELHQLEWMSEKQLQENNFYDLGEAIKLLHNPPPDISLSNLEAGEHPALKRLIFDELLAQQLSMQFARQS
RSKLQAPAILFDNAIHKRFIESLPFSLTNAQQRVFKEISFDLTQSKPMLRLLQGDVGAGKTIIAALAALQAISQGFQVAF
MAPTDLLSEQHTNSLSKWLEPIGINVLRLSGKMKTTERKNALAALQDNSCQLIVGTHALFQEQVEFARLGLVIIDEQHRF
GVEQRLLLQQKGQLNQLIPHQLLMTATPIPRTLSMSHFAHLDISVIDELPPGRMPITTAVLNQDKRELIIERLQAAIANG
KQAYWVCTLIEESEKLQCMAATDTSKKLQEQLSFARVGLVHGRMKALEKEATMAAFKQGEIDLLVATTVIEVGVDVPNAS
LMIIENAERLGLSQLHQLRGRVGRGNNQSHCLLLYQSPLSQQGAERLKIMRSTTDGFLISEKDLELRGSGEILGTRQTGF
RQFKIANLQRDKTLFAILRPIAKQLVLEKTAIARQITQRWLGNFEQFLQS

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=680, Percent_Identity=50.2941176470588, Blast_Score=659, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=404, Percent_Identity=35.3960396039604, Blast_Score=235, Evalue=7e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 78156; Mature: 78156

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSNSCEYLTGVGPTIAAKLAKCGIFTIQDLLFHLPYKYQDRTRITPIQDLRSNEWCVIA
CCCCCCCHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCEEEEE
GHVYKTEIKYGKRMMLNCYVEDKTGVVKLRFFHFNKQQIQALNNSTMIRAFGEVRGFNNH
CCEEEEHHHHCCEEEEEEEEECCCCEEEEEEEECCHHHHHHHCCCHHEEEHHHHCCCCCC
LEMIHPEYQLIDQESDFHVEETLTPIYPSTQGLTQTRLRQLVKIALEQSEHELHQLEWMS
HHHCCCHHHEECCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKQLQENNFYDLGEAIKLLHNPPPDISLSNLEAGEHPALKRLIFDELLAQQLSMQFARQS
HHHHHCCCCCCHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RSKLQAPAILFDNAIHKRFIESLPFSLTNAQQRVFKEISFDLTQSKPMLRLLQGDVGAGK
HHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCH
TIIAALAALQAISQGFQVAFMAPTDLLSEQHTNSLSKWLEPIGINVLRLSGKMKTTERKN
HHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHH
ALAALQDNSCQLIVGTHALFQEQVEFARLGLVIIDEQHRFGVEQRLLLQQKGQLNQLIPH
HHEEECCCCEEEEECHHHHHHHHHHHHHCCEEEEECHHHCCHHHHHHHHHCCCHHHHCHH
QLLMTATPIPRTLSMSHFAHLDISVIDELPPGRMPITTAVLNQDKRELIIERLQAAIANG
HHHHHCCCCCCCCCHHHHHCCCHHHHCCCCCCCCCEEHHHHCCCHHHHHHHHHHHHHHCC
KQAYWVCTLIEESEKLQCMAATDTSKKLQEQLSFARVGLVHGRMKALEKEATMAAFKQGE
CCEEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IDLLVATTVIEVGVDVPNASLMIIENAERLGLSQLHQLRGRVGRGNNQSHCLLLYQSPLS
EEEEEEHHHHHHCCCCCCCEEEEEECHHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCC
QQGAERLKIMRSTTDGFLISEKDLELRGSGEILGTRQTGFRQFKIANLQRDKTLFAILRP
HHHHHHHHHHHCCCCCEEEECCCCEECCCCCEEECCCCCCEEEEECCCCHHHHHHHHHHH
IAKQLVLEKTAIARQITQRWLGNFEQFLQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSNSCEYLTGVGPTIAAKLAKCGIFTIQDLLFHLPYKYQDRTRITPIQDLRSNEWCVIA
CCCCCCCHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCEEEEE
GHVYKTEIKYGKRMMLNCYVEDKTGVVKLRFFHFNKQQIQALNNSTMIRAFGEVRGFNNH
CCEEEEHHHHCCEEEEEEEEECCCCEEEEEEEECCHHHHHHHCCCHHEEEHHHHCCCCCC
LEMIHPEYQLIDQESDFHVEETLTPIYPSTQGLTQTRLRQLVKIALEQSEHELHQLEWMS
HHHCCCHHHEECCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKQLQENNFYDLGEAIKLLHNPPPDISLSNLEAGEHPALKRLIFDELLAQQLSMQFARQS
HHHHHCCCCCCHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RSKLQAPAILFDNAIHKRFIESLPFSLTNAQQRVFKEISFDLTQSKPMLRLLQGDVGAGK
HHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCH
TIIAALAALQAISQGFQVAFMAPTDLLSEQHTNSLSKWLEPIGINVLRLSGKMKTTERKN
HHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHH
ALAALQDNSCQLIVGTHALFQEQVEFARLGLVIIDEQHRFGVEQRLLLQQKGQLNQLIPH
HHEEECCCCEEEEECHHHHHHHHHHHHHCCEEEEECHHHCCHHHHHHHHHCCCHHHHCHH
QLLMTATPIPRTLSMSHFAHLDISVIDELPPGRMPITTAVLNQDKRELIIERLQAAIANG
HHHHHCCCCCCCCCHHHHHCCCHHHHCCCCCCCCCEEHHHHCCCHHHHHHHHHHHHHHCC
KQAYWVCTLIEESEKLQCMAATDTSKKLQEQLSFARVGLVHGRMKALEKEATMAAFKQGE
CCEEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IDLLVATTVIEVGVDVPNASLMIIENAERLGLSQLHQLRGRVGRGNNQSHCLLLYQSPLS
EEEEEEHHHHHHCCCCCCCEEEEEECHHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCC
QQGAERLKIMRSTTDGFLISEKDLELRGSGEILGTRQTGFRQFKIANLQRDKTLFAILRP
HHHHHHHHHHHCCCCCEEEECCCCEECCCCCEEECCCCCCEEEEECCCCHHHHHHHHHHH
IAKQLVLEKTAIARQITQRWLGNFEQFLQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]