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The map label for this gene is dhs1

Identifier: 52842244

GI number: 52842244

Start: 2269077

End: 2270414

Strand: Direct

Name: dhs1

Synonym: lpg2027

Alternate gene names: 52842244

Gene position: 2269077-2270414 (Clockwise)

Preceding gene: 52842235

Following gene: 52842246

Centisome position: 66.78

GC content: 40.88

Gene sequence:

>1338_bases
ATGCAAGAATGGTCGCCAACTACATGGCAGAAATATTCGTATTTGCAGGCAGCTTCATACGCTGATGAAGAGCAATTAAA
TAAAGTGGTAGAACAATTAAGTTTGCTGCCCCCATTAGTTACCAGCGGTGAAATCAAACATTTAAAAAATGAAATTGCCC
AGGCTGGCCGGGGTAATGCTTTTATTCTGCAGGGTGGTGATTGTGCTGAATCTTTTAATGACTGTCGTTCAGAAGTTATA
AGTAACAAATTAAAAATCATTCTTCAAATGAGCCTAATCTTATTATATGGCTTGCGTAAACCAATTATTCGTATCGGAAG
AATAGCTGGGCAATATGCAAAACCACGCTCCTCAGATTACGAAACCATAAATGGAGTTACTTTACCCAGTTATCGTGGAG
ATATCGTTAATTCACCTGAATTTACTACCACTGCCAGGGAGCCTAATCCTAAATTATTACTTCAGGCATACAGTTGTTCT
GCCATGACTTTAAATTTTATCCGAGCGCTGCTGGATGGCGGTTTTGCTGACCTGCATCATCCTCAACGCTGGGATTTAGG
TTTTGTTGAACACTCCCCTCAGAAGAACGAATACCAACATATTGTAGACTCTATTGAAGACGCCCTGGATTTTTTGAATG
CCATAGATGGAATACGTTCGAGTAGCATAAGTAAAGTTGATTTTTACACCTCTCATGAAGCGTTGCATTTACATTATGAG
CAAGCATTAACAAGACAGTTGAAAGATGGAAAATGGTACAATCTTTCAACTCATTTACCCTGGATTGGAATGCGTACGGC
ACAAACGGACAGTGCACATCTTGAGTTTCTACGAGGGGTACAAAATCCAATAGGCATTAAGATAGGCCCAGCAGCTACAC
CTGAATGGTTATCAGAGGTATTAAGCATAGCCAATCCGCAAAAAGAAGAAGGACGAGTTTTACTTTATACTCGCCTGGGA
GCAAAACTTATCGACCGGTTGTTACCTCCACTGATTGACACAGTAAGGAAAAGCAAAATTCCAGTCACGTGGTCATGTGA
CCCTATGCATGGCAATACCGAAACAACAGAAGACGGTACTAAAACACGTCACTTCGATAACATTTTATCGGAATTAAAAC
AAGCTTTGGAAATTCATCGCAGCATGGGTAGCTACCTTGGAGGTGTCCATTTTGAGCTAACTGGTGACAATGTAACAGAG
TGTATCGGGGGCGCTCGTGGATTAGCTCCTCATGATCTCAAAACTGCCTATCACAGCCTGGTTGATCCAAGATTAAACTA
TGAACAATCTCTGGAAATGGCCATCCAATTAAGCCATCAATTCAGAAATGAATCTTAA

Upstream 100 bases:

>100_bases
TCTTAATTCTCATTTAGGTAAAAAAATCAAAGTATTTAATAATCCTTTGAGTTAAATTAAGTCTAAACGACAACTAAAGC
AAAAATAACTTGGGTAAATT

Downstream 100 bases:

>100_bases
TGAAATTCATGACGTCTTGAATGAAGGCCAGTATCTATGCCAAAAGCTGATTATCTGTAACTGTTCATGCAATGGCGTGT
ACGGTTACGATTGTCTGATT

Product: 2-keto-3-deoxy-D-arabino-heptulosonate 7-phosphate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MQEWSPTTWQKYSYLQAASYADEEQLNKVVEQLSLLPPLVTSGEIKHLKNEIAQAGRGNAFILQGGDCAESFNDCRSEVI
SNKLKIILQMSLILLYGLRKPIIRIGRIAGQYAKPRSSDYETINGVTLPSYRGDIVNSPEFTTTAREPNPKLLLQAYSCS
AMTLNFIRALLDGGFADLHHPQRWDLGFVEHSPQKNEYQHIVDSIEDALDFLNAIDGIRSSSISKVDFYTSHEALHLHYE
QALTRQLKDGKWYNLSTHLPWIGMRTAQTDSAHLEFLRGVQNPIGIKIGPAATPEWLSEVLSIANPQKEEGRVLLYTRLG
AKLIDRLLPPLIDTVRKSKIPVTWSCDPMHGNTETTEDGTKTRHFDNILSELKQALEIHRSMGSYLGGVHFELTGDNVTE
CIGGARGLAPHDLKTAYHSLVDPRLNYEQSLEMAIQLSHQFRNES

Sequences:

>Translated_445_residues
MQEWSPTTWQKYSYLQAASYADEEQLNKVVEQLSLLPPLVTSGEIKHLKNEIAQAGRGNAFILQGGDCAESFNDCRSEVI
SNKLKIILQMSLILLYGLRKPIIRIGRIAGQYAKPRSSDYETINGVTLPSYRGDIVNSPEFTTTAREPNPKLLLQAYSCS
AMTLNFIRALLDGGFADLHHPQRWDLGFVEHSPQKNEYQHIVDSIEDALDFLNAIDGIRSSSISKVDFYTSHEALHLHYE
QALTRQLKDGKWYNLSTHLPWIGMRTAQTDSAHLEFLRGVQNPIGIKIGPAATPEWLSEVLSIANPQKEEGRVLLYTRLG
AKLIDRLLPPLIDTVRKSKIPVTWSCDPMHGNTETTEDGTKTRHFDNILSELKQALEIHRSMGSYLGGVHFELTGDNVTE
CIGGARGLAPHDLKTAYHSLVDPRLNYEQSLEMAIQLSHQFRNES
>Mature_445_residues
MQEWSPTTWQKYSYLQAASYADEEQLNKVVEQLSLLPPLVTSGEIKHLKNEIAQAGRGNAFILQGGDCAESFNDCRSEVI
SNKLKIILQMSLILLYGLRKPIIRIGRIAGQYAKPRSSDYETINGVTLPSYRGDIVNSPEFTTTAREPNPKLLLQAYSCS
AMTLNFIRALLDGGFADLHHPQRWDLGFVEHSPQKNEYQHIVDSIEDALDFLNAIDGIRSSSISKVDFYTSHEALHLHYE
QALTRQLKDGKWYNLSTHLPWIGMRTAQTDSAHLEFLRGVQNPIGIKIGPAATPEWLSEVLSIANPQKEEGRVLLYTRLG
AKLIDRLLPPLIDTVRKSKIPVTWSCDPMHGNTETTEDGTKTRHFDNILSELKQALEIHRSMGSYLGGVHFELTGDNVTE
CIGGARGLAPHDLKTAYHSLVDPRLNYEQSLEMAIQLSHQFRNES

Specific function: Unknown

COG id: COG3200

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II DAHP synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002480 [H]

Pfam domain/function: PF01474 DAHP_synth_2 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 50032; Mature: 50032

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEWSPTTWQKYSYLQAASYADEEQLNKVVEQLSLLPPLVTSGEIKHLKNEIAQAGRGNA
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCE
FILQGGDCAESFNDCRSEVISNKLKIILQMSLILLYGLRKPIIRIGRIAGQYAKPRSSDY
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ETINGVTLPSYRGDIVNSPEFTTTAREPNPKLLLQAYSCSAMTLNFIRALLDGGFADLHH
CCCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHCCC
PQRWDLGFVEHSPQKNEYQHIVDSIEDALDFLNAIDGIRSSSISKVDFYTSHEALHLHYE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHH
QALTRQLKDGKWYNLSTHLPWIGMRTAQTDSAHLEFLRGVQNPIGIKIGPAATPEWLSEV
HHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCHHHHHHH
LSIANPQKEEGRVLLYTRLGAKLIDRLLPPLIDTVRKSKIPVTWSCDPMHGNTETTEDGT
HHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCC
KTRHFDNILSELKQALEIHRSMGSYLGGVHFELTGDNVTECIGGARGLAPHDLKTAYHSL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCCCCCCCHHHHHHHHHH
VDPRLNYEQSLEMAIQLSHQFRNES
CCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQEWSPTTWQKYSYLQAASYADEEQLNKVVEQLSLLPPLVTSGEIKHLKNEIAQAGRGNA
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCE
FILQGGDCAESFNDCRSEVISNKLKIILQMSLILLYGLRKPIIRIGRIAGQYAKPRSSDY
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ETINGVTLPSYRGDIVNSPEFTTTAREPNPKLLLQAYSCSAMTLNFIRALLDGGFADLHH
CCCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHCCC
PQRWDLGFVEHSPQKNEYQHIVDSIEDALDFLNAIDGIRSSSISKVDFYTSHEALHLHYE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHH
QALTRQLKDGKWYNLSTHLPWIGMRTAQTDSAHLEFLRGVQNPIGIKIGPAATPEWLSEV
HHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCHHHHHHH
LSIANPQKEEGRVLLYTRLGAKLIDRLLPPLIDTVRKSKIPVTWSCDPMHGNTETTEDGT
HHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCC
KTRHFDNILSELKQALEIHRSMGSYLGGVHFELTGDNVTECIGGARGLAPHDLKTAYHSL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCCCCCCCHHHHHHHHHH
VDPRLNYEQSLEMAIQLSHQFRNES
CCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953; 8760910 [H]