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The map label for this gene is minD

Identifier: 52841952

GI number: 52841952

Start: 1922931

End: 1923761

Strand: Direct

Name: minD

Synonym: lpg1724

Alternate gene names: 52841952

Gene position: 1922931-1923761 (Clockwise)

Preceding gene: 52841948

Following gene: 52841959

Centisome position: 56.59

GC content: 39.11

Gene sequence:

>831_bases
TTGGCTAAAATAATAGTAATTACATCTGGGAAAGGCGGAGTAGGTAAAACTACTTCATCAGCAGCGATTTCTTCGGGACT
TGCACTCTTAGGGCATAAAACTGTTGTTATTGATTTTGATATCGGTTTAAGAAACCTGGATATCATTATGGGCTGTGAAA
GACGTGTAGTTTATGACTTCATCAACGTCATCAATGGTGAAGCCAACTTAAACCAAGCTCTCATCAAAGACAAACGGATC
CCTAACCTTTGCATACTGCCCGCATCACAAACTCGTGATAAAGACGCACTAACTCTGGAAGGAGTAGAAAAAACTCTCAA
TGAGCTAGCAAAAGATTTTGATTTCATTATTTGTGACTCCCCTGCTGGAATTGAAACTGGAGCACTTATGGCAATGTATT
TTGCTGATCATGCCATTGTTGTTACTAATCCTGAAGTCTCTTCTGTTAGAGATTCAGATAGAATTCTGGGAATACTGGCC
AGCAAAACAAAAAGAGCTATAGAAAATAAAGCACCTGTTCAAGAGCACTTGTTATTGACACGATATGATCCTGAGCGAGT
AGAACGAGGTGAAATGTTGTCTGTAACTGATGTAAAGGAAATATTAGCTATTCCTTTAATCGGTGTTATACCTGAGTCCA
AATCGGTTCTTAAAGCATCCAATACTGGTACGCCAGTTATTCTGGATGAATCAAGCGATGCGGGCATTGCTTATCAAGAC
GCCATAGCACGCTTTTTGGGCGAAGAAAGACCAATGCGATTTATAAGTATTGATAAAAAAGGACTATTTCGTCGCTTATT
CAGTAAAAACAAGGAGGAAGTGACAATATGA

Upstream 100 bases:

>100_bases
TAACAATTAAGCTTTGGATAACTTGAATTAATGAATGAATAACGTGTAAACTGTTGGTTAAATATTGTGTTGAATCGAAA
AAAATAGGAAGGGTTCAGCG

Downstream 100 bases:

>100_bases
GTATCTTCAATTACTTACGCAGAAGAGCCTCAACCGCTTCTGTTGCTAAAGAACGCTTACAAATCATCATTTCTCATGAG
CGTTCTCAACGCAATACACC

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MAKIIVITSGKGGVGKTTSSAAISSGLALLGHKTVVIDFDIGLRNLDIIMGCERRVVYDFINVINGEANLNQALIKDKRI
PNLCILPASQTRDKDALTLEGVEKTLNELAKDFDFIICDSPAGIETGALMAMYFADHAIVVTNPEVSSVRDSDRILGILA
SKTKRAIENKAPVQEHLLLTRYDPERVERGEMLSVTDVKEILAIPLIGVIPESKSVLKASNTGTPVILDESSDAGIAYQD
AIARFLGEERPMRFISIDKKGLFRRLFSKNKEEVTI

Sequences:

>Translated_276_residues
MAKIIVITSGKGGVGKTTSSAAISSGLALLGHKTVVIDFDIGLRNLDIIMGCERRVVYDFINVINGEANLNQALIKDKRI
PNLCILPASQTRDKDALTLEGVEKTLNELAKDFDFIICDSPAGIETGALMAMYFADHAIVVTNPEVSSVRDSDRILGILA
SKTKRAIENKAPVQEHLLLTRYDPERVERGEMLSVTDVKEILAIPLIGVIPESKSVLKASNTGTPVILDESSDAGIAYQD
AIARFLGEERPMRFISIDKKGLFRRLFSKNKEEVTI
>Mature_275_residues
AKIIVITSGKGGVGKTTSSAAISSGLALLGHKTVVIDFDIGLRNLDIIMGCERRVVYDFINVINGEANLNQALIKDKRIP
NLCILPASQTRDKDALTLEGVEKTLNELAKDFDFIICDSPAGIETGALMAMYFADHAIVVTNPEVSSVRDSDRILGILAS
KTKRAIENKAPVQEHLLLTRYDPERVERGEMLSVTDVKEILAIPLIGVIPESKSVLKASNTGTPVILDESSDAGIAYQDA
IARFLGEERPMRFISIDKKGLFRRLFSKNKEEVTI

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=268, Percent_Identity=74.6268656716418, Blast_Score=405, Evalue=1e-114,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 30139; Mature: 30008

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIIVITSGKGGVGKTTSSAAISSGLALLGHKTVVIDFDIGLRNLDIIMGCERRVVYDF
CEEEEEEECCCCCCCCCCCHHHHHCCHHHHCCEEEEEEECCCCCCEEEEECCCHHHHHHH
INVINGEANLNQALIKDKRIPNLCILPASQTRDKDALTLEGVEKTLNELAKDFDFIICDS
HHHHCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEECC
PAGIETGALMAMYFADHAIVVTNPEVSSVRDSDRILGILASKTKRAIENKAPVQEHLLLT
CCCCCHHHHHEEEECCCEEEEECCCHHHCCCCHHEEEHHHHHHHHHHHCCCCHHHCEEEE
RYDPERVERGEMLSVTDVKEILAIPLIGVIPESKSVLKASNTGTPVILDESSDAGIAYQD
ECCHHHHCCCCEEEHHHHHHHHHHCCEEECCCCCHHEEECCCCCEEEEECCCCCCCHHHH
AIARFLGEERPMRFISIDKKGLFRRLFSKNKEEVTI
HHHHHHCCCCCEEEEEECHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AKIIVITSGKGGVGKTTSSAAISSGLALLGHKTVVIDFDIGLRNLDIIMGCERRVVYDF
EEEEEEECCCCCCCCCCCHHHHHCCHHHHCCEEEEEEECCCCCCEEEEECCCHHHHHHH
INVINGEANLNQALIKDKRIPNLCILPASQTRDKDALTLEGVEKTLNELAKDFDFIICDS
HHHHCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEECC
PAGIETGALMAMYFADHAIVVTNPEVSSVRDSDRILGILASKTKRAIENKAPVQEHLLLT
CCCCCHHHHHEEEECCCEEEEECCCHHHCCCCHHEEEHHHHHHHHHHHCCCCHHHCEEEE
RYDPERVERGEMLSVTDVKEILAIPLIGVIPESKSVLKASNTGTPVILDESSDAGIAYQD
ECCHHHHCCCCEEEHHHHHHHHHHCCEEECCCCCHHEEECCCCCEEEEECCCCCCCHHHH
AIARFLGEERPMRFISIDKKGLFRRLFSKNKEEVTI
HHHHHHCCCCCEEEEEECHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]