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The map label for this gene is xasA [C]

Identifier: 52841886

GI number: 52841886

Start: 1833912

End: 1835249

Strand: Direct

Name: xasA [C]

Synonym: lpg1658

Alternate gene names: 52841886

Gene position: 1833912-1835249 (Clockwise)

Preceding gene: 52841885

Following gene: 52841887

Centisome position: 53.97

GC content: 38.49

Gene sequence:

>1338_bases
CTGCTTGTCGTTGAGATTTTAATGAAAAGCCGCTTATCTGTTTTAAGTCTTGCCTTAATCACTGTTTGCTCGGTTGATAG
CATTAGAAATCTTCCAGCAGCCGCTTTAGCGGGGAACCAGCTGTTTTATTACTTTGCATTGGCCTTGCTATTCTTTCTTC
TCCCTTGCGCCATTGTTGCAGTTTGGTTCTCCAGGCAATCAGAACAAGGTGTGTATGGGTGGGTAAAACAAGGACTAGGG
AATCAGTGGGCATTCATCGCCATTTGGTTTCAATGTATTCAGAATGTTTTAATTTACCCTACCTTATTGAGTTTTATTGC
TGGCACCCTGCTCTACAGCATCTCCCCTGATTTAGTTCAAAACAAAAGTATGCTTTTTCTAATTATTATTTTTTTGATTT
GGAGTTTAACCTGGATTAATTTAAAAGGAATTCATCTCTCAAGTCGTTTTAACTCTTATTGCTCCATAACGGGATTAATT
CTTCCTTTTATTATTATCCTGTTCGTGGGATTGTACTGGTGGATTACGCAGGTTAAACCTGGTACCACAGTTCTACCACC
AGCCGAACCTTATTCCTGGACTTCGCTTACTGCAATTATTTTGTCATTTTGCGGTATTGAATTAGCCGCGGTTCACGCAC
GGGACAGTAAACAAGGGGCTTTCCCTAAAGCCATAGCTATTTCAGTTATTACAATCTTTCTGACGATGTTATTTGGTTCG
ATCGTATTGGCTATGATCATTCCCCCAGAACAATTAAATTTTATCAGCAGCATTCCCCAGCTCATACAATTATTTTTTAA
TAAAATTGGTTATGGATATTTTGCCTTTATTATTAATGGATTGATCGCAATAGGTTGTATAGGTGCAGCAAATAACTGGC
TCATTGCACCTATAAAAGGATTAGAATTTGCAATAAACGAAGGGTTCTTAAATAGGCAACTCAGTCAAGTGAATAAACAT
AACGCACCTTTCAGATTGTTAGTCGCACAAGCTTTCTGTGTATCGATTATTAGTGCTTTATTTCTTATCGTACCTTCGAT
TAATGCATCTTACTGGATCATGTTGAATGCAGCGACACAAATTAATTTATTAATGTACCTCTTGCTCTTCATTAGCGCTA
TCAAAATAGTTTCCTCAAAACCGATTTTAAGTAAGCTAAATATAATGATTCCCGCTTACCTGGGGTTGGCAGGCAGTGGC
ATTACCTTAATTGTAAGTTTGACGCCACCGCCATCACTCGCCATTAGCTCCAAATTGATTTATGCATTGCTTGGCGCAAT
TTTCCTGGTCATAATGACCTTGATTCCTATTTGGAGGAGACCTAGAGTTCTTACATGA

Upstream 100 bases:

>100_bases
CCAAAGGGTGTCCTAAAATAACCCATCGTTTATCCGAACTGGGGTTTTCAATTATTGAATTGGATATGAGCGAATTTAGA
AAGTTGGATGGTGGTTTAAG

Downstream 100 bases:

>100_bases
AAAGAAATATCCAATCCTGATTTGCAAATTCAGACGCAAGTTTCATACTCTCAGCTATAATTGAGATATTAATCATTAGT
TATTGTAAAATCAGGTTAAA

Product: amino acid antiporter

Products: L-glutamate [Cytoplasm]; 4-aminobutyrate [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MLVVEILMKSRLSVLSLALITVCSVDSIRNLPAAALAGNQLFYYFALALLFFLLPCAIVAVWFSRQSEQGVYGWVKQGLG
NQWAFIAIWFQCIQNVLIYPTLLSFIAGTLLYSISPDLVQNKSMLFLIIIFLIWSLTWINLKGIHLSSRFNSYCSITGLI
LPFIIILFVGLYWWITQVKPGTTVLPPAEPYSWTSLTAIILSFCGIELAAVHARDSKQGAFPKAIAISVITIFLTMLFGS
IVLAMIIPPEQLNFISSIPQLIQLFFNKIGYGYFAFIINGLIAIGCIGAANNWLIAPIKGLEFAINEGFLNRQLSQVNKH
NAPFRLLVAQAFCVSIISALFLIVPSINASYWIMLNAATQINLLMYLLLFISAIKIVSSKPILSKLNIMIPAYLGLAGSG
ITLIVSLTPPPSLAISSKLIYALLGAIFLVIMTLIPIWRRPRVLT

Sequences:

>Translated_445_residues
MLVVEILMKSRLSVLSLALITVCSVDSIRNLPAAALAGNQLFYYFALALLFFLLPCAIVAVWFSRQSEQGVYGWVKQGLG
NQWAFIAIWFQCIQNVLIYPTLLSFIAGTLLYSISPDLVQNKSMLFLIIIFLIWSLTWINLKGIHLSSRFNSYCSITGLI
LPFIIILFVGLYWWITQVKPGTTVLPPAEPYSWTSLTAIILSFCGIELAAVHARDSKQGAFPKAIAISVITIFLTMLFGS
IVLAMIIPPEQLNFISSIPQLIQLFFNKIGYGYFAFIINGLIAIGCIGAANNWLIAPIKGLEFAINEGFLNRQLSQVNKH
NAPFRLLVAQAFCVSIISALFLIVPSINASYWIMLNAATQINLLMYLLLFISAIKIVSSKPILSKLNIMIPAYLGLAGSG
ITLIVSLTPPPSLAISSKLIYALLGAIFLVIMTLIPIWRRPRVLT
>Mature_445_residues
MLVVEILMKSRLSVLSLALITVCSVDSIRNLPAAALAGNQLFYYFALALLFFLLPCAIVAVWFSRQSEQGVYGWVKQGLG
NQWAFIAIWFQCIQNVLIYPTLLSFIAGTLLYSISPDLVQNKSMLFLIIIFLIWSLTWINLKGIHLSSRFNSYCSITGLI
LPFIIILFVGLYWWITQVKPGTTVLPPAEPYSWTSLTAIILSFCGIELAAVHARDSKQGAFPKAIAISVITIFLTMLFGS
IVLAMIIPPEQLNFISSIPQLIQLFFNKIGYGYFAFIINGLIAIGCIGAANNWLIAPIKGLEFAINEGFLNRQLSQVNKH
NAPFRLLVAQAFCVSIISALFLIVPSINASYWIMLNAATQINLLMYLLLFISAIKIVSSKPILSKLNIMIPAYLGLAGSG
ITLIVSLTPPPSLAISSKLIYALLGAIFLVIMTLIPIWRRPRVLT

Specific function: Probable Amino Acid Transporter. Involved In Extreme Acid Resistance. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787768, Length=443, Percent_Identity=24.6049661399549, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI48994921, Length=333, Percent_Identity=26.1261261261261, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49188; Mature: 49188

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVVEILMKSRLSVLSLALITVCSVDSIRNLPAAALAGNQLFYYFALALLFFLLPCAIVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VWFSRQSEQGVYGWVKQGLGNQWAFIAIWFQCIQNVLIYPTLLSFIAGTLLYSISPDLVQ
HHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHC
NKSMLFLIIIFLIWSLTWINLKGIHLSSRFNSYCSITGLILPFIIILFVGLYWWITQVKP
CCHHHHHHHHHHHHHHHHHEEECEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GTTVLPPAEPYSWTSLTAIILSFCGIELAAVHARDSKQGAFPKAIAISVITIFLTMLFGS
CCCCCCCCCCCCHHHHHHHHHHHHCHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
IVLAMIIPPEQLNFISSIPQLIQLFFNKIGYGYFAFIINGLIAIGCIGAANNWLIAPIKG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
LEFAINEGFLNRQLSQVNKHNAPFRLLVAQAFCVSIISALFLIVPSINASYWIMLNAATQ
CHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHH
INLLMYLLLFISAIKIVSSKPILSKLNIMIPAYLGLAGSGITLIVSLTPPPSLAISSKLI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHH
YALLGAIFLVIMTLIPIWRRPRVLT
HHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLVVEILMKSRLSVLSLALITVCSVDSIRNLPAAALAGNQLFYYFALALLFFLLPCAIVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VWFSRQSEQGVYGWVKQGLGNQWAFIAIWFQCIQNVLIYPTLLSFIAGTLLYSISPDLVQ
HHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHC
NKSMLFLIIIFLIWSLTWINLKGIHLSSRFNSYCSITGLILPFIIILFVGLYWWITQVKP
CCHHHHHHHHHHHHHHHHHEEECEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GTTVLPPAEPYSWTSLTAIILSFCGIELAAVHARDSKQGAFPKAIAISVITIFLTMLFGS
CCCCCCCCCCCCHHHHHHHHHHHHCHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
IVLAMIIPPEQLNFISSIPQLIQLFFNKIGYGYFAFIINGLIAIGCIGAANNWLIAPIKG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
LEFAINEGFLNRQLSQVNKHNAPFRLLVAQAFCVSIISALFLIVPSINASYWIMLNAATQ
CHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHH
INLLMYLLLFISAIKIVSSKPILSKLNIMIPAYLGLAGSGITLIVSLTPPPSLAISSKLI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHH
YALLGAIFLVIMTLIPIWRRPRVLT
HHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-aminobutyrate [Cytoplasm]; L-glutamate [Periplasm] [C]

Specific reaction: 4-aminobutyrate [Cytoplasm] + L-glutamate [Periplasm] = L-glutamate [Cytoplasm] + 4-aminobutyrate [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8366052 [H]