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The map label for this gene is fabH [H]

Identifier: 52841859

GI number: 52841859

Start: 1801305

End: 1802288

Strand: Reverse

Name: fabH [H]

Synonym: lpg1631

Alternate gene names: 52841859

Gene position: 1802288-1801305 (Counterclockwise)

Preceding gene: 52841862

Following gene: 52841858

Centisome position: 53.04

GC content: 42.38

Gene sequence:

>984_bases
ATGTCGTCAGCAAAAATCATCGGAATGGGAAAATATTTACCCGCAAACATAGTGTTTTCATCTGATCTGGATAAAAAACT
CAATCTTCCTGAAGGCAGTGTTCAGAAGAAGTCCGGATTAGTTTCCAGGCATTTTGCCAGAGTCAGTGAAACAACCTCCT
ATATGGCAAGTCAAGCTGCATTACACGCTGTGGAACAAGCAGGAATTACTTTAGCTGAAATTGATGCCATTATTGGGGCG
TGTGGAGCCGGAGAGCAACCTATACCATGTACGGCGGTTCTGGTTCAAAAACAATTGGGATTAGATAATTCAGGAATCGC
CTGTTTTGATATTAACAGTACCTGTCTTAGTTTTCTCACTGCACTCGATGCGGCATCATATATGCTCTCAGGGGGCAGAT
TTAATCGTATACTTATTGTATCAAGTGATATCCCTTCATTTGGCCTGGATTGGAGCGACTTGGAAACCTGTACGATTTTT
GGTGACGGGGCAGCTGCTTGTGTTGTTGAAAGAAGCAATGACTATAGTCGAATTCTTGCTGCTCATATGAAAACATACAG
TTTTGGTGCTGACTTTTGCCAGGTCCAGGCTGGAGGAACATTCATGCCGCCTGCAAGTGAGTACGATAAGAAATACGGTT
TATTTAAAATGGATGGAAAGCGTGTATTCAAACTGGCCAGCCAAATGATTGGACCCATGCAAGAGGAGTTATTTGCTAAA
GCTAGTATAACTCTAAATGATGTTGATTGGGTTGTCCCACATCAAGCCAGCTTGCTTGCTATGCATCATATACGTAAAAA
GCTTGGCATCCCTGGTGAAAAATTTGTTGATATTTACACGACGCATGGCAATCAAATGGCTGCTTCTCTGCCTTCCGCAT
TGTGTCATTTGATCCATAATCATAATTTAGAACGCGGGCAGTTGGTTTATTTATTAGGTACTGGCGCTGGATTGTCAGCT
GCTGGAATGATACTGGAGTATTAG

Upstream 100 bases:

>100_bases
TGCACGGCAATTATTTACCAACCAACCTTTAAAAAGTTCTCTTTGACTATAATAGGCCTTATAGTACAATAATTGCTCCA
TCCTTTAACAAGTCAGTTCT

Downstream 100 bases:

>100_bases
TATGATTTCAGTTGTAACCGGCGCTACAGGATGTTTAGGTTTAAATCTTACAAGACGCTTGATTAAGGAAGGCCATGCAG
TCATTGCATTAGGACGCAAT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MSSAKIIGMGKYLPANIVFSSDLDKKLNLPEGSVQKKSGLVSRHFARVSETTSYMASQAALHAVEQAGITLAEIDAIIGA
CGAGEQPIPCTAVLVQKQLGLDNSGIACFDINSTCLSFLTALDAASYMLSGGRFNRILIVSSDIPSFGLDWSDLETCTIF
GDGAAACVVERSNDYSRILAAHMKTYSFGADFCQVQAGGTFMPPASEYDKKYGLFKMDGKRVFKLASQMIGPMQEELFAK
ASITLNDVDWVVPHQASLLAMHHIRKKLGIPGEKFVDIYTTHGNQMAASLPSALCHLIHNHNLERGQLVYLLGTGAGLSA
AGMILEY

Sequences:

>Translated_327_residues
MSSAKIIGMGKYLPANIVFSSDLDKKLNLPEGSVQKKSGLVSRHFARVSETTSYMASQAALHAVEQAGITLAEIDAIIGA
CGAGEQPIPCTAVLVQKQLGLDNSGIACFDINSTCLSFLTALDAASYMLSGGRFNRILIVSSDIPSFGLDWSDLETCTIF
GDGAAACVVERSNDYSRILAAHMKTYSFGADFCQVQAGGTFMPPASEYDKKYGLFKMDGKRVFKLASQMIGPMQEELFAK
ASITLNDVDWVVPHQASLLAMHHIRKKLGIPGEKFVDIYTTHGNQMAASLPSALCHLIHNHNLERGQLVYLLGTGAGLSA
AGMILEY
>Mature_326_residues
SSAKIIGMGKYLPANIVFSSDLDKKLNLPEGSVQKKSGLVSRHFARVSETTSYMASQAALHAVEQAGITLAEIDAIIGAC
GAGEQPIPCTAVLVQKQLGLDNSGIACFDINSTCLSFLTALDAASYMLSGGRFNRILIVSSDIPSFGLDWSDLETCTIFG
DGAAACVVERSNDYSRILAAHMKTYSFGADFCQVQAGGTFMPPASEYDKKYGLFKMDGKRVFKLASQMIGPMQEELFAKA
SITLNDVDWVVPHQASLLAMHHIRKKLGIPGEKFVDIYTTHGNQMAASLPSALCHLIHNHNLERGQLVYLLGTGAGLSAA
GMILEY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=329, Percent_Identity=31.0030395136778, Blast_Score=157, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35125; Mature: 34994

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAKIIGMGKYLPANIVFSSDLDKKLNLPEGSVQKKSGLVSRHFARVSETTSYMASQAA
CCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHH
LHAVEQAGITLAEIDAIIGACGAGEQPIPCTAVLVQKQLGLDNSGIACFDINSTCLSFLT
HHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHH
ALDAASYMLSGGRFNRILIVSSDIPSFGLDWSDLETCTIFGDGAAACVVERSNDYSRILA
HHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCHHHHHH
AHMKTYSFGADFCQVQAGGTFMPPASEYDKKYGLFKMDGKRVFKLASQMIGPMQEELFAK
HHHHHHCCCCCEEEEECCCCCCCCCHHHHHHCCEEEECHHHHHHHHHHHHCHHHHHHHHH
ASITLNDVDWVVPHQASLLAMHHIRKKLGIPGEKFVDIYTTHGNQMAASLPSALCHLIHN
HEEEECCCCEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHC
HNLERGQLVYLLGTGAGLSAAGMILEY
CCCCCCCEEEEEECCCCCHHCCCEECC
>Mature Secondary Structure 
SSAKIIGMGKYLPANIVFSSDLDKKLNLPEGSVQKKSGLVSRHFARVSETTSYMASQAA
CCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHH
LHAVEQAGITLAEIDAIIGACGAGEQPIPCTAVLVQKQLGLDNSGIACFDINSTCLSFLT
HHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHH
ALDAASYMLSGGRFNRILIVSSDIPSFGLDWSDLETCTIFGDGAAACVVERSNDYSRILA
HHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCHHHHHH
AHMKTYSFGADFCQVQAGGTFMPPASEYDKKYGLFKMDGKRVFKLASQMIGPMQEELFAK
HHHHHHCCCCCEEEEECCCCCCCCCHHHHHHCCEEEECHHHHHHHHHHHHCHHHHHHHHH
ASITLNDVDWVVPHQASLLAMHHIRKKLGIPGEKFVDIYTTHGNQMAASLPSALCHLIHN
HEEEECCCCEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHC
HNLERGQLVYLLGTGAGLSAAGMILEY
CCCCCCCEEEEEECCCCCHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]