Click here to switch to the map view.

The map label for this gene is ruvB

Identifier: 52841806

GI number: 52841806

Start: 1741547

End: 1742578

Strand: Reverse

Name: ruvB

Synonym: lpg1576

Alternate gene names: 52841806

Gene position: 1742578-1741547 (Counterclockwise)

Preceding gene: 52841807

Following gene: 52841805

Centisome position: 51.29

GC content: 42.05

Gene sequence:

>1032_bases
ATGAACCCGATAAAACCTCTTATGCTCGAAAGTGATCGCCTAATAAGTAGTCAAAGTATTGTCTCGGAAGACGCAATGGA
TAGAGCCATCAGGCCGCTTAGCTTGAGCGAGTACGTAGGGCAAGATTCTGTTAGCTCACAGATGCAGATATTTATCAATG
CGGCAAGAAAGAGAAACGATCCTTTGGATCATGTTCTTATTTTTGGCCCACCTGGCCTTGGTAAAACTACCCTTGCAAAT
ATCATAGCTCACGAAATGGGAGTGAATATCAGACAAACTTCTGGGCCAGTGATTGAGCGTGCTGGCGATATTGCTGCTAT
ATTGACGAATCTACAACAAAATGATGTACTATTTATTGATGAAATTCATAGATTAAGTCCTGTTATAGAAGAAATTCTTT
ATCCAGCCATGGAAGATTATAAGTTGGATATCATGATAGGAGAGGGGCCAGCAGCACGATCCATTAAATTGGAGTTACCT
CCCTTTACATTAATTGGAGCAACGACAAGAGCAGGGTTGCTTACCTCGCCATTAAGGGATAGATTTGGTATAGTGCAACG
TTTGGAATATTATTCTGTTGATTCGCTTACCCAGATTGTGGCACGCTCCGCGCATTTGCTTGGTGTCCCTACAAAACCCG
AAGGAGCCAGAGAAATTGCATTACGCTCCAGAGGAACACCACGAATAGCCAATCGCCTGTTAAGAAGAGTCAGGGATTAT
TCTGAAGTGAAAGGAAATGGCATCATTACTGTTGATATGGCTCAACAAGCATTGGAAATGCTTGAAGTGGATCAGCACGG
GTTTGATTTAATGGATAGAAAATTATTGTTAGCGGTGATAGAACACTTCAATGGTGGTCCAGTAGGCATAGATAGTATTG
CAGCTGCTATTGGCGAAGAAAAAGGGACTATAGAAGATGTTTTGGAGCCATTTTTAATACAACAAGGCTTTCTAATGCGC
ACTCCTCGCGGTAGAATAGCCACTTCGAAAGCTTATCAGCATTTTGGCTTTAGTGCGATCGAACAGGAATAA

Upstream 100 bases:

>100_bases
ATCAACCTTAATCGTGAAATCAATTGCATTTAATTATTAAATAAATAAGCTTACAAAGATCTGCTATTAGATAAACCTAT
GTTAAAATGCTTTCATTCGA

Downstream 100 bases:

>100_bases
CACATGAATCTTATATCAAATCATCAGCATAACATTAGAGTCTATGCAGAAGATGTTGATTATATGGGAATTGTTTATCA
TGCTAACTACCTTTGTTATT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MNPIKPLMLESDRLISSQSIVSEDAMDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRNDPLDHVLIFGPPGLGKTTLAN
IIAHEMGVNIRQTSGPVIERAGDIAAILTNLQQNDVLFIDEIHRLSPVIEEILYPAMEDYKLDIMIGEGPAARSIKLELP
PFTLIGATTRAGLLTSPLRDRFGIVQRLEYYSVDSLTQIVARSAHLLGVPTKPEGAREIALRSRGTPRIANRLLRRVRDY
SEVKGNGIITVDMAQQALEMLEVDQHGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEEKGTIEDVLEPFLIQQGFLMR
TPRGRIATSKAYQHFGFSAIEQE

Sequences:

>Translated_343_residues
MNPIKPLMLESDRLISSQSIVSEDAMDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRNDPLDHVLIFGPPGLGKTTLAN
IIAHEMGVNIRQTSGPVIERAGDIAAILTNLQQNDVLFIDEIHRLSPVIEEILYPAMEDYKLDIMIGEGPAARSIKLELP
PFTLIGATTRAGLLTSPLRDRFGIVQRLEYYSVDSLTQIVARSAHLLGVPTKPEGAREIALRSRGTPRIANRLLRRVRDY
SEVKGNGIITVDMAQQALEMLEVDQHGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEEKGTIEDVLEPFLIQQGFLMR
TPRGRIATSKAYQHFGFSAIEQE
>Mature_343_residues
MNPIKPLMLESDRLISSQSIVSEDAMDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRNDPLDHVLIFGPPGLGKTTLAN
IIAHEMGVNIRQTSGPVIERAGDIAAILTNLQQNDVLFIDEIHRLSPVIEEILYPAMEDYKLDIMIGEGPAARSIKLELP
PFTLIGATTRAGLLTSPLRDRFGIVQRLEYYSVDSLTQIVARSAHLLGVPTKPEGAREIALRSRGTPRIANRLLRRVRDY
SEVKGNGIITVDMAQQALEMLEVDQHGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEEKGTIEDVLEPFLIQQGFLMR
TPRGRIATSKAYQHFGFSAIEQE

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=334, Percent_Identity=72.1556886227545, Blast_Score=497, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37899; Mature: 37899

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPIKPLMLESDRLISSQSIVSEDAMDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRND
CCCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCC
PLDHVLIFGPPGLGKTTLANIIAHEMGVNIRQTSGPVIERAGDIAAILTNLQQNDVLFID
CCCEEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHCCHHHHHHHCCCCCCEEEHH
EIHRLSPVIEEILYPAMEDYKLDIMIGEGPAARSIKLELPPFTLIGATTRAGLLTSPLRD
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCHHCCHHHHHHHH
RFGIVQRLEYYSVDSLTQIVARSAHLLGVPTKPEGAREIALRSRGTPRIANRLLRRVRDY
HHHHHHHHHHHCHHHHHHHHHHHHHEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHH
SEVKGNGIITVDMAQQALEMLEVDQHGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEE
HHHCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
KGTIEDVLEPFLIQQGFLMRTPRGRIATSKAYQHFGFSAIEQE
CCCHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MNPIKPLMLESDRLISSQSIVSEDAMDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRND
CCCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCC
PLDHVLIFGPPGLGKTTLANIIAHEMGVNIRQTSGPVIERAGDIAAILTNLQQNDVLFID
CCCEEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHCCHHHHHHHCCCCCCEEEHH
EIHRLSPVIEEILYPAMEDYKLDIMIGEGPAARSIKLELPPFTLIGATTRAGLLTSPLRD
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCHHCCHHHHHHHH
RFGIVQRLEYYSVDSLTQIVARSAHLLGVPTKPEGAREIALRSRGTPRIANRLLRRVRDY
HHHHHHHHHHHCHHHHHHHHHHHHHEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHH
SEVKGNGIITVDMAQQALEMLEVDQHGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEE
HHHCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
KGTIEDVLEPFLIQQGFLMRTPRGRIATSKAYQHFGFSAIEQE
CCCHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA