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The map label for this gene is htpG

Identifier: 52841599

GI number: 52841599

Start: 1514897

End: 1516768

Strand: Direct

Name: htpG

Synonym: lpg1369

Alternate gene names: 52841599

Gene position: 1514897-1516768 (Clockwise)

Preceding gene: 52841598

Following gene: 52841603

Centisome position: 44.59

GC content: 37.77

Gene sequence:

>1872_bases
ATGGTTAGCAAGCAGCAAACTATGGGATTTCAAACAGAGGTAAAGCAAATGCTTCATTTGGTTGTGCATTCGCTTTATAG
CAACAAAGAGATTTTTCTTAGAGAATTAATTTCTAATGCTTCTGATGCCTTGGACAAGTTACGATTTTTAGCTTTATCAA
ACGGGTCATTGTTTGAAAATGATTCTGATTTGAAAATTAGCATTCAGATTAATGAAAAGCTTCAAACCATTACCATCAGC
GATAATGGGATTGGTCTGAGTTGGGAAGAGGCAGTAGAAAATTTGGGGACAATTGCAAAATCCGGAACAAAAGAATTTAT
TAGCCAATTAACTGGTGAACAAGCAAAGGATTCTCAACTAATAGGACAATTTGGAGTGGGTTTTTATTCCGCGTTTATCG
TTGCTGATAAAGTAACAGTTAAAAGTCGCCGCGCTGGGTTACAACCTGAGGATGGAATTGTATGGGAGTCTAAGGGTGAT
GGTGAATTTACTATAGGATATGAAAAAAAATCGACCCGCGGTACAGAAATTACCTTGCACTTAAAACCTGAAAACGACGA
GTTTTTAAGTGATTGGCGTATTCGCGGTATTATTAGTAAATACTCTGATCATATTTGTTGGCCTATTGTGATGAAAAAGC
TTTCAGAGGAAGGCAAAGAATCAAAAGAATTTGAAACAGTAAACAAGGCGACGGCACTTTGGACACTACAGAAATCTGAA
ATTAGCGAAGAAGACTATAAGCAACTGTATAAACATATTTCTCATGATTACATGGATCCATTAACCTGGTCTCATAACCA
TGTTGAAGGAAAACACGAGTATATTACTTTGCTTTACATACCAGCCCATGCCCCATTTGATTTATGGCAGCATGAAGCCA
AACATGGACTAAAGCTTTATGTAAAGCGTGTATTTATTATGGATGAAGCGACACAATTTTTACCCCGATATTTACGATTT
GTAAAAGGGATTGTGGATGCCAGTGATTTACCGCTTAATATTTCTCGAGAAATATTACAGGATAACAAGCAGGTAGAATC
TATTCGAGCTGCATGCACCAAACGTGTTTTGTCTATGCTTGAAAAAATGGCTACCAATGATAAAGAAACCTATCAGAAGT
TTTGGAATGAATTTGGACTTGTGCTAAAAGAAGGACCTATTGAGGATTTCGCTAATAAGGAAGCGATTGCCAAGTTGCTT
CGTTTTTCTACTACAGCAAGCGGTAGTGAGAAACAAGAAGTATCGCTGGAGGAATATGTTAGTCGCATGAAAGAAGGGCA
GGATAAAATTTATTATATTACCGCATCGAGTTACAATGCTGCTAAAAATAGCCCTCATTTGGAAATATTCAGGAAAAAGG
GAATTGAGGTATTATTGCTCAGTGATAAAGTCGATGAATGGCTTGTAGGTTATATGAATGAGTTTGCAGGCAAAAAACTA
CAGTCAATTTCAAAAGGCAAGGTTGAATTGGGAGATGATGAAACTTCCGAACAAATTAAAGAACAGGAAAAAACCCTGGA
GCCATTGATTAAGCATATTAAATCAGTTCTAAATGAGCGAGTTAAAGATGTATTGCTGACTAATCGTCTTACTGATTCCC
CTGCATGTGTTGTTGCTGATGAGCAAGACATGGGATTGGAAATGCAAAGAATTTTACAAGCTGCGGGTCAACAGGTTCCA
GTGAGCAAGCCTATTTTTGAAATTAATCCGGATCATGCCCTGATTAAGCGGTTGCATGATATTCAGGATGATAACCAATT
TGAATTATGGGTTACTATGCTGTTTGAACAAGCTGTGTTGGCAGAAGGAGGGCAATTGGATAATCCCGCTGATTTTGTGA
ATCGGGTTAACAGACTTCTGGTTTCCTCCTAG

Upstream 100 bases:

>100_bases
GGTTTCCTCTTTTTTAGCGCTATCCCCTTGAAATTTAATAGATCAACCCTATATGAGAAGTTAATTATTCGAACACAACT
ATTAACGGGGAGATTGTTTA

Downstream 100 bases:

>100_bases
AATTCTATAGGGTTGGCAATCAATCCCGGATTACAACAAGTCATTATCCGGGATGAGCTGAACATAAAATAAAAAGGCTC
AAAAATGAGCCTTTTTATTT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFENDSDLKISIQINEKLQTITIS
DNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQLIGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGD
GEFTIGYEKKSTRGTEITLHLKPENDEFLSDWRIRGIISKYSDHICWPIVMKKLSEEGKESKEFETVNKATALWTLQKSE
ISEEDYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLYVKRVFIMDEATQFLPRYLRF
VKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSMLEKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLL
RFSTTASGSEKQEVSLEEYVSRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFAGKKL
QSISKGKVELGDDETSEQIKEQEKTLEPLIKHIKSVLNERVKDVLLTNRLTDSPACVVADEQDMGLEMQRILQAAGQQVP
VSKPIFEINPDHALIKRLHDIQDDNQFELWVTMLFEQAVLAEGGQLDNPADFVNRVNRLLVSS

Sequences:

>Translated_623_residues
MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFENDSDLKISIQINEKLQTITIS
DNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQLIGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGD
GEFTIGYEKKSTRGTEITLHLKPENDEFLSDWRIRGIISKYSDHICWPIVMKKLSEEGKESKEFETVNKATALWTLQKSE
ISEEDYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLYVKRVFIMDEATQFLPRYLRF
VKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSMLEKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLL
RFSTTASGSEKQEVSLEEYVSRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFAGKKL
QSISKGKVELGDDETSEQIKEQEKTLEPLIKHIKSVLNERVKDVLLTNRLTDSPACVVADEQDMGLEMQRILQAAGQQVP
VSKPIFEINPDHALIKRLHDIQDDNQFELWVTMLFEQAVLAEGGQLDNPADFVNRVNRLLVSS
>Mature_623_residues
MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFENDSDLKISIQINEKLQTITIS
DNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQLIGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGD
GEFTIGYEKKSTRGTEITLHLKPENDEFLSDWRIRGIISKYSDHICWPIVMKKLSEEGKESKEFETVNKATALWTLQKSE
ISEEDYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLYVKRVFIMDEATQFLPRYLRF
VKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSMLEKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLL
RFSTTASGSEKQEVSLEEYVSRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFAGKKL
QSISKGKVELGDDETSEQIKEQEKTLEPLIKHIKSVLNERVKDVLLTNRLTDSPACVVADEQDMGLEMQRILQAAGQQVP
VSKPIFEINPDHALIKRLHDIQDDNQFELWVTMLFEQAVLAEGGQLDNPADFVNRVNRLLVSS

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=630, Percent_Identity=36.984126984127, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI154146191, Length=408, Percent_Identity=38.7254901960784, Blast_Score=278, Evalue=9e-75,
Organism=Homo sapiens, GI153792590, Length=408, Percent_Identity=38.7254901960784, Blast_Score=276, Evalue=4e-74,
Organism=Homo sapiens, GI20149594, Length=408, Percent_Identity=38.9705882352941, Blast_Score=276, Evalue=5e-74,
Organism=Homo sapiens, GI4507677, Length=212, Percent_Identity=45.2830188679245, Blast_Score=178, Evalue=1e-44,
Organism=Escherichia coli, GI1786679, Length=621, Percent_Identity=62.3188405797101, Blast_Score=818, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=671, Percent_Identity=39.4932935916543, Blast_Score=454, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17542208, Length=674, Percent_Identity=36.053412462908, Blast_Score=404, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI115535205, Length=648, Percent_Identity=33.4876543209877, Blast_Score=318, Evalue=4e-87,
Organism=Caenorhabditis elegans, GI115535167, Length=438, Percent_Identity=36.986301369863, Blast_Score=259, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6323840, Length=674, Percent_Identity=39.0207715133531, Blast_Score=445, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6325016, Length=678, Percent_Identity=38.6430678466077, Blast_Score=442, Evalue=1e-125,
Organism=Drosophila melanogaster, GI17647529, Length=685, Percent_Identity=38.2481751824818, Blast_Score=463, Evalue=1e-130,
Organism=Drosophila melanogaster, GI21357739, Length=681, Percent_Identity=36.2701908957416, Blast_Score=397, Evalue=1e-110,
Organism=Drosophila melanogaster, GI24586016, Length=642, Percent_Identity=35.202492211838, Blast_Score=361, Evalue=1e-99,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71053; Mature: 71053

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFEN
CCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DSDLKISIQINEKLQTITISDNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQL
CCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHH
IGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGDGEFTIGYEKKSTRGTEITLH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEECCCCCCCCEEEEE
LKPENDEFLSDWRIRGIISKYSDHICWPIVMKKLSEEGKESKEFETVNKATALWTLQKSE
ECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEHHH
ISEEDYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLY
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
VKRVFIMDEATQFLPRYLRFVKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSML
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
EKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLLRFSTTASGSEKQEVSLEEYV
HHHHCCCHHHHHHHHHHHCCEEECCCCHHHCCHHHHHHHHHHHCCCCCCCHHCCCHHHHH
SRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFAGKKL
HHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHH
QSISKGKVELGDDETSEQIKEQEKTLEPLIKHIKSVLNERVKDVLLTNRLTDSPACVVAD
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
EQDMGLEMQRILQAAGQQVPVSKPIFEINPDHALIKRLHDIQDDNQFELWVTMLFEQAVL
CCCCCHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AEGGQLDNPADFVNRVNRLLVSS
HCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFEN
CCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DSDLKISIQINEKLQTITISDNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQL
CCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHH
IGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGDGEFTIGYEKKSTRGTEITLH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEECCCCCCCCEEEEE
LKPENDEFLSDWRIRGIISKYSDHICWPIVMKKLSEEGKESKEFETVNKATALWTLQKSE
ECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEHHH
ISEEDYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLY
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
VKRVFIMDEATQFLPRYLRFVKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSML
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
EKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLLRFSTTASGSEKQEVSLEEYV
HHHHCCCHHHHHHHHHHHCCEEECCCCHHHCCHHHHHHHHHHHCCCCCCCHHCCCHHHHH
SRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFAGKKL
HHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHH
QSISKGKVELGDDETSEQIKEQEKTLEPLIKHIKSVLNERVKDVLLTNRLTDSPACVVAD
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
EQDMGLEMQRILQAAGQQVPVSKPIFEINPDHALIKRLHDIQDDNQFELWVTMLFEQAVL
CCCCCHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AEGGQLDNPADFVNRVNRLLVSS
HCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA