Click here to switch to the map view.

The map label for this gene is trpD

Identifier: 52841070

GI number: 52841070

Start: 914284

End: 915318

Strand: Reverse

Name: trpD

Synonym: lpg0834

Alternate gene names: 52841070

Gene position: 915318-914284 (Counterclockwise)

Preceding gene: 52841071

Following gene: 52841069

Centisome position: 26.94

GC content: 40.77

Gene sequence:

>1035_bases
ATGAAACCCAAACTTCTATTTGAACAACTTCTATCCCGACAGGATTTAAGCTCAGACCAGATGCAAGAGGTCATCCATGC
TTGTATGACAGGTGAATTTAGTGATGTGCAAATTGCAACCTTTCTGGCATTAATGCGCATGAAAGGTGAAACAGTCAATG
AACTTACTGCAGCGGCTCAAGTCATGAGACAATTAGCCCACAAAATAGATTTGGGAAATCCCCTGATAGATATAGTTGGC
ACTGGCGGTGATGGAAGAAATACTTTTAACGTATCGACAGCCTGTAGTTTTGTTGTAGCTGCAGCAGGAATAAAAGTTGC
AAAGCATGGTAACCGTTCTGTTTCGAGTCGTAGCGGTAGCGCTGATCTATTAGAACAAGCCGGATTTATACTCAATCTTT
CTGACTCACAGGTACAAAACTGCATCAACCAGTGTCAATTGGCTTTCTTGTTTGCGCCACATTATCATCCCGCCATGCAA
CACGCGAGAGCTGCAAGGCAACAATTAGGAATAAGAACTTTATTTAATTTACTTGGTCCACTGATTAACCCGGCTCAGGT
AAAACGACAAGTAGTTGGTGTGTTTTCAACGAATTGGCTCAAAACAATAGCCACTGTTCTGGCTAACTTAGGTAGTGAAA
GATCATTAGTAATAAGCTCTCAAGATGGACTGGATGAGATTAGTATTGCAGCGAAAAGTGAAGTAGTTGAATACCGAGAT
GGAAATTTTAAGCAATGGTTCATTTCTCCTGAAGATTATGGTCTAAAGCATTCTTCTTTAGATGCAATCATAGTCGACTC
ACCAGAGCAAAGCCTGCATTTGATTCAATCCGTACTTTCAGGTGATTCTGGCCCAGCTCGAGATATAGTCCTTCTCAATT
CTGCCGCAGCCATTTATTGTGCCAAAGATGGCATATCGTTTGATGCGGCCATAGAGGAAGCAAGAATTGCCATTGATAGT
GGTAAGGCAAATCTTTGTTTTAACAAACTCCGATTATTGACCCAAACTTTAAATAAAGAATCAAATCATGAATAG

Upstream 100 bases:

>100_bases
GCAATATCACATCGTCAATTTCCTCTTTTTGGTCTACAATTTCATCCTGAAGCCATATTAAGTCAATTTGGCTTGCAAAT
ACTCGAGAATTTTTTACGCT

Downstream 100 bases:

>100_bases
TATCCTGGAACGAATAGCAAAACATAAACTAGAAGAAGTTGCAGTTGCGAAAAAAAATAAGCCTTTACATGTTCTGTCAA
AACAACAGCCGGGGGAAATG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKPKLLFEQLLSRQDLSSDQMQEVIHACMTGEFSDVQIATFLALMRMKGETVNELTAAAQVMRQLAHKIDLGNPLIDIVG
TGGDGRNTFNVSTACSFVVAAAGIKVAKHGNRSVSSRSGSADLLEQAGFILNLSDSQVQNCINQCQLAFLFAPHYHPAMQ
HARAARQQLGIRTLFNLLGPLINPAQVKRQVVGVFSTNWLKTIATVLANLGSERSLVISSQDGLDEISIAAKSEVVEYRD
GNFKQWFISPEDYGLKHSSLDAIIVDSPEQSLHLIQSVLSGDSGPARDIVLLNSAAAIYCAKDGISFDAAIEEARIAIDS
GKANLCFNKLRLLTQTLNKESNHE

Sequences:

>Translated_344_residues
MKPKLLFEQLLSRQDLSSDQMQEVIHACMTGEFSDVQIATFLALMRMKGETVNELTAAAQVMRQLAHKIDLGNPLIDIVG
TGGDGRNTFNVSTACSFVVAAAGIKVAKHGNRSVSSRSGSADLLEQAGFILNLSDSQVQNCINQCQLAFLFAPHYHPAMQ
HARAARQQLGIRTLFNLLGPLINPAQVKRQVVGVFSTNWLKTIATVLANLGSERSLVISSQDGLDEISIAAKSEVVEYRD
GNFKQWFISPEDYGLKHSSLDAIIVDSPEQSLHLIQSVLSGDSGPARDIVLLNSAAAIYCAKDGISFDAAIEEARIAIDS
GKANLCFNKLRLLTQTLNKESNHE
>Mature_344_residues
MKPKLLFEQLLSRQDLSSDQMQEVIHACMTGEFSDVQIATFLALMRMKGETVNELTAAAQVMRQLAHKIDLGNPLIDIVG
TGGDGRNTFNVSTACSFVVAAAGIKVAKHGNRSVSSRSGSADLLEQAGFILNLSDSQVQNCINQCQLAFLFAPHYHPAMQ
HARAARQQLGIRTLFNLLGPLINPAQVKRQVVGVFSTNWLKTIATVLANLGSERSLVISSQDGLDEISIAAKSEVVEYRD
GNFKQWFISPEDYGLKHSSLDAIIVDSPEQSLHLIQSVLSGDSGPARDIVLLNSAAAIYCAKDGISFDAAIEEARIAIDS
GKANLCFNKLRLLTQTLNKESNHE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=277, Percent_Identity=41.1552346570397, Blast_Score=197, Evalue=8e-52,
Organism=Saccharomyces cerevisiae, GI6320561, Length=351, Percent_Identity=31.3390313390313, Blast_Score=140, Evalue=3e-34,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_LEGPA (Q5X6R9)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_123224.1
- ProteinModelPortal:   Q5X6R9
- SMR:   Q5X6R9
- STRING:   Q5X6R9
- GeneID:   3116973
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp0896
- LegioList:   lpp0896
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   HGNKSAS
- ProtClustDB:   PRK00188
- BioCyc:   LPNE297246:LPP0896-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 37365; Mature: 37365

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKLLFEQLLSRQDLSSDQMQEVIHACMTGEFSDVQIATFLALMRMKGETVNELTAAAQ
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
VMRQLAHKIDLGNPLIDIVGTGGDGRNTFNVSTACSFVVAAAGIKVAKHGNRSVSSRSGS
HHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
ADLLEQAGFILNLSDSQVQNCINQCQLAFLFAPHYHPAMQHARAARQQLGIRTLFNLLGP
HHHHHHCCCEEECCHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LINPAQVKRQVVGVFSTNWLKTIATVLANLGSERSLVISSQDGLDEISIAAKSEVVEYRD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCC
GNFKQWFISPEDYGLKHSSLDAIIVDSPEQSLHLIQSVLSGDSGPARDIVLLNSAAAIYC
CCCEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEE
AKDGISFDAAIEEARIAIDSGKANLCFNKLRLLTQTLNKESNHE
ECCCCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKPKLLFEQLLSRQDLSSDQMQEVIHACMTGEFSDVQIATFLALMRMKGETVNELTAAAQ
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
VMRQLAHKIDLGNPLIDIVGTGGDGRNTFNVSTACSFVVAAAGIKVAKHGNRSVSSRSGS
HHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
ADLLEQAGFILNLSDSQVQNCINQCQLAFLFAPHYHPAMQHARAARQQLGIRTLFNLLGP
HHHHHHCCCEEECCHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LINPAQVKRQVVGVFSTNWLKTIATVLANLGSERSLVISSQDGLDEISIAAKSEVVEYRD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCC
GNFKQWFISPEDYGLKHSSLDAIIVDSPEQSLHLIQSVLSGDSGPARDIVLLNSAAAIYC
CCCEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEE
AKDGISFDAAIEEARIAIDSGKANLCFNKLRLLTQTLNKESNHE
ECCCCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA