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The map label for this gene is add [H]

Identifier: 52840742

GI number: 52840742

Start: 535517

End: 536992

Strand: Reverse

Name: add [H]

Synonym: lpg0497

Alternate gene names: 52840742

Gene position: 536992-535517 (Counterclockwise)

Preceding gene: 52840744

Following gene: 52840735

Centisome position: 15.8

GC content: 39.23

Gene sequence:

>1476_bases
ATGAACATTACCAGATTACTCGCATTTTTTACCAGTTCCTTTTTTTTGTGTCCAACATACGCCAGTGTTGATTCCTATTT
TAGTCATATAAAAAAGGATTCCAGTGCCCTTTATGCCTTTTTTAAAACAATGCCCAAGGGTGGCGAGTTACATTATCATT
TGGCTGGAGGAGCCTATCCTGAGACCATGCTGGCGCTCGCCGCAAATGGCAACTACTGCCTGGATAAACACACCTTTGCC
GTCAGTAAAGATTCTTCTCATTGTGAGGGAGTTAATGTTAAAGAAGTCTTTAACAACCCTGAACTCTATTCCAACATCAT
TAAAGACTGGTCTATGAAAGATTTTATACCGGGTAAAGAATCTGGCCACGATCATTTTTTCAATGGATTTATCAAATACA
TGCCTATAGTTTTTGATTATCAACCGCAATTGCTTGCTGATATTGTTCAACGTGCCGCACAGCAAAAAGCACAATACTTG
GAAATTATGACAATCCCAGACAATGCCCAGTCATTAACTTATGGGGATTTAATCAAGGATATTCCATCGTATGACCAAAA
AAGACGCTTGTTATTAGCGAATAAAGATTTTCAAAGCAACATACAAAATACCGTTTTGGAAAGTGACCGAATTCTTACCA
AAGCATCTCAAGAGTTACGCTGCAACGAGAACCCTGCTTCCGACTCCTGCCATGTAAAAATTAAATTCCTCTATTATGTG
CTCAGAGAGCAGCCTGTTGATAACGTCTTTGCCCAAGCATTGAACGCTTTTGAGGCTGTATCGAAATCCAAGGGGAATTT
AATCGGGGTAAACCTCGTGCAGCCGGAAGATGGAATTATTTCTTTGCGTGATTACCAAAAGCACATGTCCATCTTTGAAT
ACCTGCATCGAATATACCCGAATGTTCCGATCACCTTACATGCCGGAGAATTATCTCCTCAGGCAGTAACACCAGAAAAT
CTAAGTCATCATATTCGCGATGCACTGCTGATTGGGCACGCCCAAAGAATTGGCCACGGTGTGGATATCGGTTATGAAAA
CAATGCAGAAGATACCTTAAAATACATGGCTAACCATCACATACCCGTTGAAATCAATTTGATTAGTAATTTAAAAATTC
TGGATATATCTGGCTCCAATCATCCTCTTAATTATTATCTTTCCCATAATGTACCTGTCGTTTTATCCACTGATGACGAA
GGAGTGCTAAGAACGGACTTAACCCAACAATATGTAGAGGCGGCTAAAGAACATGGCCTTAGTTATCAACAATTAAAACA
AATTAATAGAAACACATTAACTTATTCCTTCTTACCTGGGAAAAGCATATGGGCTAATGCGGATAAAGCCGAATTGGTTC
CTGATTGTCATGACCTTGGGAGCAAAAGTTGTCAAAAATTTATTGCGCACAACGAAAAAGCAAAATTGCAATGGAATCTG
GAACAACAATTAATTGCCTTTGAGAAGAGTTACTAA

Upstream 100 bases:

>100_bases
TAAAAAATAATAAGAGATTGCATGATAAAACAGATATTCTGTTGGGAATCGTGCAAGATTATGAGATAATATCTGACCAA
TTAATGATCACATTGAAATT

Downstream 100 bases:

>100_bases
ATTAATTTGCAAAACAATGAGTCCATATTAGGAGAAATGCAAAATAGCATTTCATTATGCACTAATATGGGCCTCATAAT
CCAAGGTTCTATTGATCCAA

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MNITRLLAFFTSSFFLCPTYASVDSYFSHIKKDSSALYAFFKTMPKGGELHYHLAGGAYPETMLALAANGNYCLDKHTFA
VSKDSSHCEGVNVKEVFNNPELYSNIIKDWSMKDFIPGKESGHDHFFNGFIKYMPIVFDYQPQLLADIVQRAAQQKAQYL
EIMTIPDNAQSLTYGDLIKDIPSYDQKRRLLLANKDFQSNIQNTVLESDRILTKASQELRCNENPASDSCHVKIKFLYYV
LREQPVDNVFAQALNAFEAVSKSKGNLIGVNLVQPEDGIISLRDYQKHMSIFEYLHRIYPNVPITLHAGELSPQAVTPEN
LSHHIRDALLIGHAQRIGHGVDIGYENNAEDTLKYMANHHIPVEINLISNLKILDISGSNHPLNYYLSHNVPVVLSTDDE
GVLRTDLTQQYVEAAKEHGLSYQQLKQINRNTLTYSFLPGKSIWANADKAELVPDCHDLGSKSCQKFIAHNEKAKLQWNL
EQQLIAFEKSY

Sequences:

>Translated_491_residues
MNITRLLAFFTSSFFLCPTYASVDSYFSHIKKDSSALYAFFKTMPKGGELHYHLAGGAYPETMLALAANGNYCLDKHTFA
VSKDSSHCEGVNVKEVFNNPELYSNIIKDWSMKDFIPGKESGHDHFFNGFIKYMPIVFDYQPQLLADIVQRAAQQKAQYL
EIMTIPDNAQSLTYGDLIKDIPSYDQKRRLLLANKDFQSNIQNTVLESDRILTKASQELRCNENPASDSCHVKIKFLYYV
LREQPVDNVFAQALNAFEAVSKSKGNLIGVNLVQPEDGIISLRDYQKHMSIFEYLHRIYPNVPITLHAGELSPQAVTPEN
LSHHIRDALLIGHAQRIGHGVDIGYENNAEDTLKYMANHHIPVEINLISNLKILDISGSNHPLNYYLSHNVPVVLSTDDE
GVLRTDLTQQYVEAAKEHGLSYQQLKQINRNTLTYSFLPGKSIWANADKAELVPDCHDLGSKSCQKFIAHNEKAKLQWNL
EQQLIAFEKSY
>Mature_491_residues
MNITRLLAFFTSSFFLCPTYASVDSYFSHIKKDSSALYAFFKTMPKGGELHYHLAGGAYPETMLALAANGNYCLDKHTFA
VSKDSSHCEGVNVKEVFNNPELYSNIIKDWSMKDFIPGKESGHDHFFNGFIKYMPIVFDYQPQLLADIVQRAAQQKAQYL
EIMTIPDNAQSLTYGDLIKDIPSYDQKRRLLLANKDFQSNIQNTVLESDRILTKASQELRCNENPASDSCHVKIKFLYYV
LREQPVDNVFAQALNAFEAVSKSKGNLIGVNLVQPEDGIISLRDYQKHMSIFEYLHRIYPNVPITLHAGELSPQAVTPEN
LSHHIRDALLIGHAQRIGHGVDIGYENNAEDTLKYMANHHIPVEINLISNLKILDISGSNHPLNYYLSHNVPVVLSTDDE
GVLRTDLTQQYVEAAKEHGLSYQQLKQINRNTLTYSFLPGKSIWANADKAELVPDCHDLGSKSCQKFIAHNEKAKLQWNL
EQQLIAFEKSY

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Escherichia coli, GI1787910, Length=147, Percent_Identity=35.3741496598639, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006650
- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 55656; Mature: 55656

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITRLLAFFTSSFFLCPTYASVDSYFSHIKKDSSALYAFFKTMPKGGELHYHLAGGAYP
CCHHHHHHHHHCCCEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCCC
ETMLALAANGNYCLDKHTFAVSKDSSHCEGVNVKEVFNNPELYSNIIKDWSMKDFIPGKE
HHEEEEECCCCEEECCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHCCCCHHCCCCCC
SGHDHFFNGFIKYMPIVFDYQPQLLADIVQRAAQQKAQYLEIMTIPDNAQSLTYGDLIKD
CCCCHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHH
IPSYDQKRRLLLANKDFQSNIQNTVLESDRILTKASQELRCNENPASDSCHVKIKFLYYV
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCEEEEHHHHHH
LREQPVDNVFAQALNAFEAVSKSKGNLIGVNLVQPEDGIISLRDYQKHMSIFEYLHRIYP
HHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCC
NVPITLHAGELSPQAVTPENLSHHIRDALLIGHAQRIGHGVDIGYENNAEDTLKYMANHH
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHCCC
IPVEINLISNLKILDISGSNHPLNYYLSHNVPVVLSTDDEGVLRTDLTQQYVEAAKEHGL
CCEEEEEECCEEEEEECCCCCCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHCCC
SYQQLKQINRNTLTYSFLPGKSIWANADKAELVPDCHDLGSKSCQKFIAHNEKAKLQWNL
CHHHHHHHCCCEEEEEECCCCCCCCCCCCHHCCCCHHHCCHHHHHHHHHCCCCCEEEECH
EQQLIAFEKSY
HHHHHHHHCCC
>Mature Secondary Structure
MNITRLLAFFTSSFFLCPTYASVDSYFSHIKKDSSALYAFFKTMPKGGELHYHLAGGAYP
CCHHHHHHHHHCCCEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCCC
ETMLALAANGNYCLDKHTFAVSKDSSHCEGVNVKEVFNNPELYSNIIKDWSMKDFIPGKE
HHEEEEECCCCEEECCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHCCCCHHCCCCCC
SGHDHFFNGFIKYMPIVFDYQPQLLADIVQRAAQQKAQYLEIMTIPDNAQSLTYGDLIKD
CCCCHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHH
IPSYDQKRRLLLANKDFQSNIQNTVLESDRILTKASQELRCNENPASDSCHVKIKFLYYV
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCEEEEHHHHHH
LREQPVDNVFAQALNAFEAVSKSKGNLIGVNLVQPEDGIISLRDYQKHMSIFEYLHRIYP
HHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCC
NVPITLHAGELSPQAVTPENLSHHIRDALLIGHAQRIGHGVDIGYENNAEDTLKYMANHH
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHCCC
IPVEINLISNLKILDISGSNHPLNYYLSHNVPVVLSTDDEGVLRTDLTQQYVEAAKEHGL
CCEEEEEECCEEEEEECCCCCCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHCCC
SYQQLKQINRNTLTYSFLPGKSIWANADKAELVPDCHDLGSKSCQKFIAHNEKAKLQWNL
CHHHHHHHCCCEEEEEECCCCCCCCCCCCHHCCCCHHHCCHHHHHHHHHCCCCCEEEECH
EQQLIAFEKSY
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA