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The map label for this gene is htpX

Identifier: 52840435

GI number: 52840435

Start: 209967

End: 210809

Strand: Reverse

Name: htpX

Synonym: lpg0180

Alternate gene names: 52840435

Gene position: 210809-209967 (Counterclockwise)

Preceding gene: 52840437

Following gene: 52840428

Centisome position: 6.2

GC content: 43.53

Gene sequence:

>843_bases
ATGATAAATAACCTGAAAACTTTTATCTTGTTAGCCTCTCTAACAGCATTGTTAGTTGTTATTGGGGGATTGCTTGGAGG
CTCTACAGGAATGCTGATTGCATTAGTATTTGCAGGAGTTATGAATTTTTCAGCTTACTGGTACTCTGATGTTCTTGTTT
TGAAAATGTATAATGCTGAACCTCTGCCCAATAATCACTTTGTTAACAATATTATTTCAGAACTTGCGCATAGGGCAGGA
ACCCCTGTACCCAAAGTTTATTTAATTAATAACTCTACTCCAAACGCGTTTGCAACAGGGAGAAATCCAGAGAATGCCAG
TATCGCTGTGACAACAGGATTGTTAGATAGGCTCACTCAAGAGGAAATCACCGGAGTTTTAGCTCATGAACTGGCCCATG
TAATCCACCGCGACACTTTAATTAATGTGGTAAGCGCAACGATAGCAGGGGCGATTAGCGGGATTGCCAATATGTTCATG
TGGCTTTCAATGTTTGGCCACAATTCAAATAATGAAGAAGGTGTCCATCCAGTGGTTGGCATGATCATGATGATAGTAGC
TCCCCTGGCGGCTGGACTGATTCAAATGGCTATATCGCGCTCCAGGGAGTTTGAAGCGGATGCCGGTGGAGCACGAATTT
CCGGGAATCCGCAGTGGCTGGCCAGTGCCTTGTTAAAACTTGATCAAGCCAACCATGAGCAATACTTTGATGAAGCAGAA
ACTCACCCCTCCACTGCGCACCTGTTTATCATTAACCCCTTAAACGGAGAAAAGCTGGCTAACTTATTTTCAACCCATCC
ATCGACAGCAGAACGAGTAGCAAGACTAAGAGCCATGTACTAA

Upstream 100 bases:

>100_bases
GGGCATAAATAAACAGAGACAAGGTTCCAAGTTGAATTTTTAACATCTGGCCTTATTTATGAGATATAAAATATAGGAAG
AGTAAATGAGGTGATGAGAA

Downstream 100 bases:

>100_bases
TTAACAGGATGACTGATTTGGAGTAAACATTACTTTACTGACAGTAAGGAATGACTTTTAAAATTTATCAAACCCAAAAT
AAAATAATGCCCTGGAAATA

Product: M48 family peptidase

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MINNLKTFILLASLTALLVVIGGLLGGSTGMLIALVFAGVMNFSAYWYSDVLVLKMYNAEPLPNNHFVNNIISELAHRAG
TPVPKVYLINNSTPNAFATGRNPENASIAVTTGLLDRLTQEEITGVLAHELAHVIHRDTLINVVSATIAGAISGIANMFM
WLSMFGHNSNNEEGVHPVVGMIMMIVAPLAAGLIQMAISRSREFEADAGGARISGNPQWLASALLKLDQANHEQYFDEAE
THPSTAHLFIINPLNGEKLANLFSTHPSTAERVARLRAMY

Sequences:

>Translated_280_residues
MINNLKTFILLASLTALLVVIGGLLGGSTGMLIALVFAGVMNFSAYWYSDVLVLKMYNAEPLPNNHFVNNIISELAHRAG
TPVPKVYLINNSTPNAFATGRNPENASIAVTTGLLDRLTQEEITGVLAHELAHVIHRDTLINVVSATIAGAISGIANMFM
WLSMFGHNSNNEEGVHPVVGMIMMIVAPLAAGLIQMAISRSREFEADAGGARISGNPQWLASALLKLDQANHEQYFDEAE
THPSTAHLFIINPLNGEKLANLFSTHPSTAERVARLRAMY
>Mature_280_residues
MINNLKTFILLASLTALLVVIGGLLGGSTGMLIALVFAGVMNFSAYWYSDVLVLKMYNAEPLPNNHFVNNIISELAHRAG
TPVPKVYLINNSTPNAFATGRNPENASIAVTTGLLDRLTQEEITGVLAHELAHVIHRDTLINVVSATIAGAISGIANMFM
WLSMFGHNSNNEEGVHPVVGMIMMIVAPLAAGLIQMAISRSREFEADAGGARISGNPQWLASALLKLDQANHEQYFDEAE
THPSTAHLFIINPLNGEKLANLFSTHPSTAERVARLRAMY

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=261, Percent_Identity=29.8850574712644, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 30255; Mature: 30255

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINNLKTFILLASLTALLVVIGGLLGGSTGMLIALVFAGVMNFSAYWYSDVLVLKMYNAE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
PLPNNHFVNNIISELAHRAGTPVPKVYLINNSTPNAFATGRNPENASIAVTTGLLDRLTQ
CCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCCCEEEEHHHHHHHHHH
EEITGVLAHELAHVIHRDTLINVVSATIAGAISGIANMFMWLSMFGHNSNNEEGVHPVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
MIMMIVAPLAAGLIQMAISRSREFEADAGGARISGNPQWLASALLKLDQANHEQYFDEAE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHH
THPSTAHLFIINPLNGEKLANLFSTHPSTAERVARLRAMY
CCCCCEEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MINNLKTFILLASLTALLVVIGGLLGGSTGMLIALVFAGVMNFSAYWYSDVLVLKMYNAE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
PLPNNHFVNNIISELAHRAGTPVPKVYLINNSTPNAFATGRNPENASIAVTTGLLDRLTQ
CCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCCCEEEEHHHHHHHHHH
EEITGVLAHELAHVIHRDTLINVVSATIAGAISGIANMFMWLSMFGHNSNNEEGVHPVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
MIMMIVAPLAAGLIQMAISRSREFEADAGGARISGNPQWLASALLKLDQANHEQYFDEAE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHH
THPSTAHLFIINPLNGEKLANLFSTHPSTAERVARLRAMY
CCCCCEEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA