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The map label for this gene is yjcC [H]

Identifier: 52840411

GI number: 52840411

Start: 189144

End: 190304

Strand: Reverse

Name: yjcC [H]

Synonym: lpg0156

Alternate gene names: 52840411

Gene position: 190304-189144 (Counterclockwise)

Preceding gene: 52840412

Following gene: 52840410

Centisome position: 5.6

GC content: 36.26

Gene sequence:

>1161_bases
CTGTTCCTCCAAGCCTCGCGACGGAAAACATATACTATAATCAAACTAAAGGAAACCCAGTCAATCAAGGGAAATAGCAT
GCCTTGCGAAAAATGCGATTCAGCGGCAACCTACCATTTATCGGGAACCTACCAGTTACTCATTTTACCCCCACGAGGTC
ATTGCTATTCAAAATTATTAAAGCATTTAACCGAAAATAATTTTGATATCAATAAAAGAGACAGCGGAATTATCGAATTA
TTATTTACTGCTGAGAGAGCACAAGACATAGGTCATGCACTGGAGCGATGTTATTCACAAGCGGAACTTGAGGACAGCAA
AGCAGTTTTGTTGCCAATTGATATCGCGGACAGAAACGTAGAGAGAGTACTCAATCATACGCATTCATTAAAAAAAATTG
TGGGGTTGTGTTTGTCTCAATGGCTGGTTGGACTCATTGAAAATCAGGGGCTATCAACCTTCTGCCAGCCTATTTTGCAT
AATACCACACTCAAACCCTATGGTTTTGAGTGCCTTCTCAGGGGAAAGCAAGATAATAATATACTGCCTTCCTCTGATTT
ATTTGGAGCAGCAAAATCGAGCGACATGCTTTTTTTGTTAGATAAAAAAGCACGTATATGCCACATTGAAAATATGAGCA
AAATTGACATCGCTGACAAAAAAATCTTCATTAATTTTAACCCAACAGCCATTTACGATCCCCTTTTTTGCTTGACAACA
ACGAACCAATCCTTAAAAAAAACATCCATTAAACCTGCACAAATTGTATTTGAAGTCACTGAAAGTGATGAAGTAAAAGA
TAAAAAACACTTGTTAAAAATAATAGATTATTACAGAAATCAAGGTTACTGTGTCGCCCTTGACGATTTGGGCTCTGGTT
ACAGCTCTTTGAATTTGCTTACTGAGTTACAACCTGATTACGTTAAACTTGATCAAGAATTGATTAGCCAGATTCATACA
AATGAATTCAAACAAATCATATTGGAAAAAATATGTGAGATGGCTACTAAACTAAAGATAAAAATAATCTGCGAAGGCAT
AGAAACAGAAGACGAGTTACAGATTATAAAAAATTATGCCATCGATTTTTATCAAGGTTTTTTGTTTGAGAAACCTATGC
CTTACGAAAAAATACCCGACTATATCAAAGCAAGCGCATAA

Upstream 100 bases:

>100_bases
AATGGGAGCATACCATTTTAGTGACCGATAATGGACATGAAATACTGACCTTAAGAGCAGACGAGCACCTATAGACATAT
CTCCTCTTGCTTGGTAATTA

Downstream 100 bases:

>100_bases
AAATGGATTGGCTATTGGATATATGACAAATGCTTACAAACATTGAAAGAGCAAAACTTCAATTAATTGATGAAACCAAC
GATATGGTCATTATAACCAA

Product: signal transduction protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MFLQASRRKTYTIIKLKETQSIKGNSMPCEKCDSAATYHLSGTYQLLILPPRGHCYSKLLKHLTENNFDINKRDSGIIEL
LFTAERAQDIGHALERCYSQAELEDSKAVLLPIDIADRNVERVLNHTHSLKKIVGLCLSQWLVGLIENQGLSTFCQPILH
NTTLKPYGFECLLRGKQDNNILPSSDLFGAAKSSDMLFLLDKKARICHIENMSKIDIADKKIFINFNPTAIYDPLFCLTT
TNQSLKKTSIKPAQIVFEVTESDEVKDKKHLLKIIDYYRNQGYCVALDDLGSGYSSLNLLTELQPDYVKLDQELISQIHT
NEFKQIILEKICEMATKLKIKIICEGIETEDELQIIKNYAIDFYQGFLFEKPMPYEKIPDYIKASA

Sequences:

>Translated_386_residues
MFLQASRRKTYTIIKLKETQSIKGNSMPCEKCDSAATYHLSGTYQLLILPPRGHCYSKLLKHLTENNFDINKRDSGIIEL
LFTAERAQDIGHALERCYSQAELEDSKAVLLPIDIADRNVERVLNHTHSLKKIVGLCLSQWLVGLIENQGLSTFCQPILH
NTTLKPYGFECLLRGKQDNNILPSSDLFGAAKSSDMLFLLDKKARICHIENMSKIDIADKKIFINFNPTAIYDPLFCLTT
TNQSLKKTSIKPAQIVFEVTESDEVKDKKHLLKIIDYYRNQGYCVALDDLGSGYSSLNLLTELQPDYVKLDQELISQIHT
NEFKQIILEKICEMATKLKIKIICEGIETEDELQIIKNYAIDFYQGFLFEKPMPYEKIPDYIKASA
>Mature_386_residues
MFLQASRRKTYTIIKLKETQSIKGNSMPCEKCDSAATYHLSGTYQLLILPPRGHCYSKLLKHLTENNFDINKRDSGIIEL
LFTAERAQDIGHALERCYSQAELEDSKAVLLPIDIADRNVERVLNHTHSLKKIVGLCLSQWLVGLIENQGLSTFCQPILH
NTTLKPYGFECLLRGKQDNNILPSSDLFGAAKSSDMLFLLDKKARICHIENMSKIDIADKKIFINFNPTAIYDPLFCLTT
TNQSLKKTSIKPAQIVFEVTESDEVKDKKHLLKIIDYYRNQGYCVALDDLGSGYSSLNLLTELQPDYVKLDQELISQIHT
NEFKQIILEKICEMATKLKIKIICEGIETEDELQIIKNYAIDFYQGFLFEKPMPYEKIPDYIKASA

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=236, Percent_Identity=30.9322033898305, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787410, Length=216, Percent_Identity=27.3148148148148, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87081845, Length=239, Percent_Identity=29.2887029288703, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788849, Length=212, Percent_Identity=30.188679245283, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI87081980, Length=249, Percent_Identity=24.0963855421687, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=30, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787541, Length=220, Percent_Identity=28.1818181818182, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081921, Length=263, Percent_Identity=24.7148288973384, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788502, Length=234, Percent_Identity=25.2136752136752, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786507, Length=260, Percent_Identity=25.3846153846154, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI226510982, Length=240, Percent_Identity=25.4166666666667, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87082096, Length=130, Percent_Identity=26.1538461538462, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787055, Length=152, Percent_Identity=30.2631578947368, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 44062; Mature: 44062

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLQASRRKTYTIIKLKETQSIKGNSMPCEKCDSAATYHLSGTYQLLILPPRGHCYSKLL
CCCCCCCCCEEEEEEEECCCCCCCCCCCHHHCCCCCEEEECCEEEEEEECCCCHHHHHHH
KHLTENNFDINKRDSGIIELLFTAERAQDIGHALERCYSQAELEDSKAVLLPIDIADRNV
HHHHCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHH
ERVLNHTHSLKKIVGLCLSQWLVGLIENQGLSTFCQPILHNTTLKPYGFECLLRGKQDNN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCC
ILPSSDLFGAAKSSDMLFLLDKKARICHIENMSKIDIADKKIFINFNPTAIYDPLFCLTT
CCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCEEEECCCEEEEEECCCCHHCCEEEEEC
TNQSLKKTSIKPAQIVFEVTESDEVKDKKHLLKIIDYYRNQGYCVALDDLGSGYSSLNLL
CCCHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHH
TELQPDYVKLDQELISQIHTNEFKQIILEKICEMATKLKIKIICEGIETEDELQIIKNYA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHH
IDFYQGFLFEKPMPYEKIPDYIKASA
HHHHHHHHCCCCCCHHHCCHHHHCCC
>Mature Secondary Structure
MFLQASRRKTYTIIKLKETQSIKGNSMPCEKCDSAATYHLSGTYQLLILPPRGHCYSKLL
CCCCCCCCCEEEEEEEECCCCCCCCCCCHHHCCCCCEEEECCEEEEEEECCCCHHHHHHH
KHLTENNFDINKRDSGIIELLFTAERAQDIGHALERCYSQAELEDSKAVLLPIDIADRNV
HHHHCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHH
ERVLNHTHSLKKIVGLCLSQWLVGLIENQGLSTFCQPILHNTTLKPYGFECLLRGKQDNN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCC
ILPSSDLFGAAKSSDMLFLLDKKARICHIENMSKIDIADKKIFINFNPTAIYDPLFCLTT
CCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCEEEECCCEEEEEECCCCHHCCEEEEEC
TNQSLKKTSIKPAQIVFEVTESDEVKDKKHLLKIIDYYRNQGYCVALDDLGSGYSSLNLL
CCCHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHH
TELQPDYVKLDQELISQIHTNEFKQIILEKICEMATKLKIKIICEGIETEDELQIIKNYA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHH
IDFYQGFLFEKPMPYEKIPDYIKASA
HHHHHHHHCCCCCCHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]