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The map label for this gene is yegE [H]

Identifier: 52840410

GI number: 52840410

Start: 188236

End: 189114

Strand: Reverse

Name: yegE [H]

Synonym: lpg0155

Alternate gene names: 52840410

Gene position: 189114-188236 (Counterclockwise)

Preceding gene: 52840411

Following gene: 52840408

Centisome position: 5.57

GC content: 34.47

Gene sequence:

>879_bases
ATGCTTACAAACATTGAAAGAGCAAAACTTCAATTAATTGATGAAACCAACGATATGGTCATTATAACCAAAGCAGAACC
ACTTGATGCACCTAATGGTCCGGAAGTGGTTTGGGTGAATAAAGCCTTTGAAAACATTTCAAAATATAAAGCCAATGAAA
TTATTGGCCAAACACCACGTATCCTTCAAGGTAAAGAAACCAATCAAAACACATTAAAAATGATAAAAGAAGCACTTAAA
GCTCAAACGAATATCAATGTGGATTTATTAAACTATACTAAGGATGGAACACCTTATTGGATTAGTTTTTCAATAGTTTA
TTTAAGAGACGGGCAGGGTAATTTATGTTATTTAGGCGCAATAGAAAAAGACATCACCGCACTCAAGAATTTAAATTTTA
AATTATCTGAAAAAGCAAAGACTGATCCGCTTACCAATGTTTACAATCAGGAAAATTTCTTCATCGCAGGGAATGAAGCT
ATTAAAAACTTTCATCAAAACCAGGAAGCAGTTGGATTATTATTTTTCGATGTGGATGATTTTAAAGGAATAAACGATAC
GCAAGGACATATCTATGGCGATATGATATTAAAAAAAGTTGCCCAGGAATCTTTAAAGCTTGTCCGTAAAACGGATAACG
TATTTCGATATGGCGGCGATGAGTTTGCTATTATTTTTTCAGGCATTGATGTGAAAATCCTGGAAAGAAAAGCACAACAA
CTACAAAAAAAATTGGCAAAATCTCACATCTCTGTGAGCATTGGAGGGACTATTTCAATCCAAAGTGACAAATCGATAAA
CACCCTCTTGGCGAGAGCGGATGAAGCACTCTATTACGTCAAAGCCAACAAAAAAGGGTTATTTTTCATCGCAGAATAA

Upstream 100 bases:

>100_bases
ATCAAGGTTTTTTGTTTGAGAAACCTATGCCTTACGAAAAAATACCCGACTATATCAAAGCAAGCGCATAAAAATGGATT
GGCTATTGGATATATGACAA

Downstream 100 bases:

>100_bases
TCACATTTTGACGCTGCCAAATTGCGAGGAAATTAAAACCAGTGACGTTCAATCCAATGACATCGCCTTTTAAACAATTC
CTTTATGCCATGAAAAAATA

Product: sensory box protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MLTNIERAKLQLIDETNDMVIITKAEPLDAPNGPEVVWVNKAFENISKYKANEIIGQTPRILQGKETNQNTLKMIKEALK
AQTNINVDLLNYTKDGTPYWISFSIVYLRDGQGNLCYLGAIEKDITALKNLNFKLSEKAKTDPLTNVYNQENFFIAGNEA
IKNFHQNQEAVGLLFFDVDDFKGINDTQGHIYGDMILKKVAQESLKLVRKTDNVFRYGGDEFAIIFSGIDVKILERKAQQ
LQKKLAKSHISVSIGGTISIQSDKSINTLLARADEALYYVKANKKGLFFIAE

Sequences:

>Translated_292_residues
MLTNIERAKLQLIDETNDMVIITKAEPLDAPNGPEVVWVNKAFENISKYKANEIIGQTPRILQGKETNQNTLKMIKEALK
AQTNINVDLLNYTKDGTPYWISFSIVYLRDGQGNLCYLGAIEKDITALKNLNFKLSEKAKTDPLTNVYNQENFFIAGNEA
IKNFHQNQEAVGLLFFDVDDFKGINDTQGHIYGDMILKKVAQESLKLVRKTDNVFRYGGDEFAIIFSGIDVKILERKAQQ
LQKKLAKSHISVSIGGTISIQSDKSINTLLARADEALYYVKANKKGLFFIAE
>Mature_292_residues
MLTNIERAKLQLIDETNDMVIITKAEPLDAPNGPEVVWVNKAFENISKYKANEIIGQTPRILQGKETNQNTLKMIKEALK
AQTNINVDLLNYTKDGTPYWISFSIVYLRDGQGNLCYLGAIEKDITALKNLNFKLSEKAKTDPLTNVYNQENFFIAGNEA
IKNFHQNQEAVGLLFFDVDDFKGINDTQGHIYGDMILKKVAQESLKLVRKTDNVFRYGGDEFAIIFSGIDVKILERKAQQ
LQKKLAKSHISVSIGGTISIQSDKSINTLLARADEALYYVKANKKGLFFIAE

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=270, Percent_Identity=23.7037037037037, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787541, Length=261, Percent_Identity=24.5210727969349, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87081881, Length=167, Percent_Identity=32.3353293413174, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI145693134, Length=168, Percent_Identity=33.9285714285714, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787262, Length=209, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87081974, Length=162, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786584, Length=130, Percent_Identity=30, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082007, Length=183, Percent_Identity=29.5081967213115, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787816, Length=129, Percent_Identity=28.6821705426357, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788956, Length=170, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787056, Length=117, Percent_Identity=38.4615384615385, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 32890; Mature: 32890

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTNIERAKLQLIDETNDMVIITKAEPLDAPNGPEVVWVNKAFENISKYKANEIIGQTPR
CCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCC
ILQGKETNQNTLKMIKEALKAQTNINVDLLNYTKDGTPYWISFSIVYLRDGQGNLCYLGA
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEEEEECCCCCEEEEEC
IEKDITALKNLNFKLSEKAKTDPLTNVYNQENFFIAGNEAIKNFHQNQEAVGLLFFDVDD
CHHHHHHHHCCCEEECCCCCCCCCHHHCCCCCEEEECHHHHHHHHCCCCEEEEEEEECHH
FKGINDTQGHIYGDMILKKVAQESLKLVRKTDNVFRYGGDEFAIIFSGIDVKILERKAQQ
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEEECCCHHHHHHHHHH
LQKKLAKSHISVSIGGTISIQSDKSINTLLARADEALYYVKANKKGLFFIAE
HHHHHHHHHEEEEECCEEEECCCCCHHHHHHHCCCEEEEEEECCCEEEEEEC
>Mature Secondary Structure
MLTNIERAKLQLIDETNDMVIITKAEPLDAPNGPEVVWVNKAFENISKYKANEIIGQTPR
CCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCC
ILQGKETNQNTLKMIKEALKAQTNINVDLLNYTKDGTPYWISFSIVYLRDGQGNLCYLGA
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEEEEECCCCCEEEEEC
IEKDITALKNLNFKLSEKAKTDPLTNVYNQENFFIAGNEAIKNFHQNQEAVGLLFFDVDD
CHHHHHHHHCCCEEECCCCCCCCCHHHCCCCCEEEECHHHHHHHHCCCCEEEEEEEECHH
FKGINDTQGHIYGDMILKKVAQESLKLVRKTDNVFRYGGDEFAIIFSGIDVKILERKAQQ
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEEECCCHHHHHHHHHH
LQKKLAKSHISVSIGGTISIQSDKSINTLLARADEALYYVKANKKGLFFIAE
HHHHHHHHHEEEEECCEEEECCCCCHHHHHHHCCCEEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]