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The map label for this gene is gap

Identifier: 52840393

GI number: 52840393

Start: 165977

End: 167005

Strand: Reverse

Name: gap

Synonym: lpg0138

Alternate gene names: 52840393

Gene position: 167005-165977 (Counterclockwise)

Preceding gene: 52840394

Following gene: 52840392

Centisome position: 4.92

GC content: 45.0

Gene sequence:

>1029_bases
CTGAGTATGGAGGTTACCCTAACTCGGAGAAGTAGTATGACAATACGAGTCGCGATTAATGGCTATGGCCGCATTGGCCG
TTGCATTTTAAGATCGATTTTTGAATACAACAGGCAAAATGAGTTTGAAGTCGTTGCCATTAACGATTTATCTGGCATCG
ATGTGACCGCTCACCTGACTCGCTACGATTCAACTCACGGTCCTTTTCGCTCGGATGTGAGCATAGAAGGAAACATGCTG
ATTGTTGATGGGCATGGCATTCAAGTGATTGCTGAGCGCGATCCGGCCAAACTGCCATGGAAACAATTGGACATTGATAT
CGTCTTTGAATGCACCGGTTTCTTTACCAGCAGAGATGCGGCAATGGGTCATATCAATGCCGGCGCCAAAAAAGTATTAA
TATCTGCCCCGGCCAAAGGCGTTGATACGACAGTGGTCTATGGAGTTAATCACTCCGTCATCAAAGCGTCTGATGTCATT
GTGTCTAACGCTTCCTGTACAACAAACTGCCTGGCGCCAGTAGTTAAAGTGTTAAATGATGCCATAGGAATTGAATCAGG
ATTAGTCAACACTGTCCATGCTTATACAAAAGATCAAATGCTTTTGGATGGAAGCCATAAAGATTTACGGCGCGCCCGCT
CTGCAACGCAGTCCATCATTCCAACCAAAACCGGCGCTGCCGCAGCCGTTGGATTGGTTTTACCTGAACTGGCAGGGAAA
TTGGACGGATTTGCGATGCGAGTACCGGTATTAAACGTATCCGTTGTTGATTTAACTTTCCAGGCAAAACGCGCAACTTC
TGTGGAAGAAATCAATGACATCATGCGCAAGGCTAAAAACCGAATTTTACAAATTAATGAGGACCCTTTAGTTTCTTGTG
ACTTCAATCACAATCCCGCTTCCGCTATTTTCGACACAACGGAAACCAAAGTGATAGGCAATTTGGTTAAAGTAGTAGCC
TGGTATGACAATGAATGGGGTTTCTCTAACCGCATGATTGATACCGCACACCAAATGATGAACTGCTAA

Upstream 100 bases:

>100_bases
AGTAGAAAAAATTATCAATACTCTAGATACATTAACCAAACAAACAATGGTGTAACCCATACCCCTTCTGAAGTTTCAAG
AAGGCCTGTATTCAGTATAA

Downstream 100 bases:

>100_bases
AGGATAACCAATGAACCTGATTAAAATGAGCGACATTGATCTGTCTGGCAAAAGAGTTCTGATTCGTGAGGATTTAAATG
TCCCGATCAAAGACGGTATG

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSMEVTLTRRSSMTIRVAINGYGRIGRCILRSIFEYNRQNEFEVVAINDLSGIDVTAHLTRYDSTHGPFRSDVSIEGNML
IVDGHGIQVIAERDPAKLPWKQLDIDIVFECTGFFTSRDAAMGHINAGAKKVLISAPAKGVDTTVVYGVNHSVIKASDVI
VSNASCTTNCLAPVVKVLNDAIGIESGLVNTVHAYTKDQMLLDGSHKDLRRARSATQSIIPTKTGAAAAVGLVLPELAGK
LDGFAMRVPVLNVSVVDLTFQAKRATSVEEINDIMRKAKNRILQINEDPLVSCDFNHNPASAIFDTTETKVIGNLVKVVA
WYDNEWGFSNRMIDTAHQMMNC

Sequences:

>Translated_342_residues
MSMEVTLTRRSSMTIRVAINGYGRIGRCILRSIFEYNRQNEFEVVAINDLSGIDVTAHLTRYDSTHGPFRSDVSIEGNML
IVDGHGIQVIAERDPAKLPWKQLDIDIVFECTGFFTSRDAAMGHINAGAKKVLISAPAKGVDTTVVYGVNHSVIKASDVI
VSNASCTTNCLAPVVKVLNDAIGIESGLVNTVHAYTKDQMLLDGSHKDLRRARSATQSIIPTKTGAAAAVGLVLPELAGK
LDGFAMRVPVLNVSVVDLTFQAKRATSVEEINDIMRKAKNRILQINEDPLVSCDFNHNPASAIFDTTETKVIGNLVKVVA
WYDNEWGFSNRMIDTAHQMMNC
>Mature_341_residues
SMEVTLTRRSSMTIRVAINGYGRIGRCILRSIFEYNRQNEFEVVAINDLSGIDVTAHLTRYDSTHGPFRSDVSIEGNMLI
VDGHGIQVIAERDPAKLPWKQLDIDIVFECTGFFTSRDAAMGHINAGAKKVLISAPAKGVDTTVVYGVNHSVIKASDVIV
SNASCTTNCLAPVVKVLNDAIGIESGLVNTVHAYTKDQMLLDGSHKDLRRARSATQSIIPTKTGAAAAVGLVLPELAGKL
DGFAMRVPVLNVSVVDLTFQAKRATSVEEINDIMRKAKNRILQINEDPLVSCDFNHNPASAIFDTTETKVIGNLVKVVAW
YDNEWGFSNRMIDTAHQMMNC

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=332, Percent_Identity=43.6746987951807, Blast_Score=267, Evalue=1e-71,
Organism=Homo sapiens, GI7657116, Length=335, Percent_Identity=42.6865671641791, Blast_Score=250, Evalue=1e-66,
Organism=Escherichia coli, GI1789295, Length=333, Percent_Identity=48.3483483483483, Blast_Score=328, Evalue=4e-91,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=49.0853658536585, Blast_Score=302, Evalue=2e-83,
Organism=Caenorhabditis elegans, GI17534679, Length=331, Percent_Identity=48.9425981873112, Blast_Score=286, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI17534677, Length=331, Percent_Identity=48.9425981873112, Blast_Score=285, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI32566163, Length=331, Percent_Identity=48.036253776435, Blast_Score=271, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI17568413, Length=331, Percent_Identity=48.036253776435, Blast_Score=271, Evalue=4e-73,
Organism=Saccharomyces cerevisiae, GI6322468, Length=327, Percent_Identity=49.8470948012232, Blast_Score=301, Evalue=7e-83,
Organism=Saccharomyces cerevisiae, GI6322409, Length=327, Percent_Identity=48.0122324159021, Blast_Score=296, Evalue=3e-81,
Organism=Saccharomyces cerevisiae, GI6321631, Length=327, Percent_Identity=48.9296636085627, Blast_Score=292, Evalue=4e-80,
Organism=Drosophila melanogaster, GI17933600, Length=333, Percent_Identity=44.7447447447448, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI18110149, Length=333, Percent_Identity=44.7447447447448, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=45.0920245398773, Blast_Score=261, Evalue=6e-70,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=44.1441441441441, Blast_Score=258, Evalue=4e-69,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=44.1441441441441, Blast_Score=258, Evalue=4e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37364; Mature: 37233

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMEVTLTRRSSMTIRVAINGYGRIGRCILRSIFEYNRQNEFEVVAINDLSGIDVTAHLT
CCEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEE
RYDSTHGPFRSDVSIEGNMLIVDGHGIQVIAERDPAKLPWKQLDIDIVFECTGFFTSRDA
ECCCCCCCCCCCCEECCCEEEEECCCEEEEECCCCCCCCHHHCCEEEEEEEECCEECCCC
AMGHINAGAKKVLISAPAKGVDTTVVYGVNHSVIKASDVIVSNASCTTNCLAPVVKVLND
CCEECCCCCEEEEEECCCCCCCCEEEEECCCCEEEECEEEEECCCCCHHHHHHHHHHHHH
AIGIESGLVNTVHAYTKDQMLLDGSHKDLRRARSATQSIIPTKTGAAAAVGLVLPELAGK
HHCCCCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
LDGFAMRVPVLNVSVVDLTFQAKRATSVEEINDIMRKAKNRILQINEDPLVSCDFNHNPA
CCCEEEEEEEEEEEEEEEEEECHHCCCHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCC
SAIFDTTETKVIGNLVKVVAWYDNEWGFSNRMIDTAHQMMNC
HHEECCHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SMEVTLTRRSSMTIRVAINGYGRIGRCILRSIFEYNRQNEFEVVAINDLSGIDVTAHLT
CEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEE
RYDSTHGPFRSDVSIEGNMLIVDGHGIQVIAERDPAKLPWKQLDIDIVFECTGFFTSRDA
ECCCCCCCCCCCCEECCCEEEEECCCEEEEECCCCCCCCHHHCCEEEEEEEECCEECCCC
AMGHINAGAKKVLISAPAKGVDTTVVYGVNHSVIKASDVIVSNASCTTNCLAPVVKVLND
CCEECCCCCEEEEEECCCCCCCCEEEEECCCCEEEECEEEEECCCCCHHHHHHHHHHHHH
AIGIESGLVNTVHAYTKDQMLLDGSHKDLRRARSATQSIIPTKTGAAAAVGLVLPELAGK
HHCCCCCCHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
LDGFAMRVPVLNVSVVDLTFQAKRATSVEEINDIMRKAKNRILQINEDPLVSCDFNHNPA
CCCEEEEEEEEEEEEEEEEEECHHCCCHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCC
SAIFDTTETKVIGNLVKVVAWYDNEWGFSNRMIDTAHQMMNC
HHEECCHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7763137 [H]