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The map label for this gene is speA

Identifier: 52840262

GI number: 52840262

Start: 8314

End: 10206

Strand: Reverse

Name: speA

Synonym: lpg0006

Alternate gene names: 52840262

Gene position: 10206-8314 (Counterclockwise)

Preceding gene: 52840263

Following gene: 52840261

Centisome position: 0.3

GC content: 39.04

Gene sequence:

>1893_bases
ATGAACAATAATACTCTATCAGATGACAATCTTTACAACATAGAAAATTGGGGCGAGGGATACTTCCGAATTAACTCCAA
GGGAAATATTGAAATCAGTAAAAAACCCGGGAAACCGGGTGTTGAACTGCAAACTATAGTTGATGCAGCTGATCGTGCTG
GCTTGCATTTGCCTTTATTGATCCGTTGTAGTGATATTCTTCATGATAGAGTCCATAGAATATATCAGGCGTTCACCCAA
GCTCGAGAAGACACTTGTTATGCCGGTAATTATCAGCTGGTTTATCCAATTAAAGTAAACCAGGAACAAAGTGTGGTACG
GGAATTGTTAAAATCGCCTGATAATCAGATAGGCCTGGAGGCAGGCAGCAAACCTGAATTGATGGCGGTTATAGGTATGC
TGGGTGACCATCAGAGTACTATAGTTTGCAACGGCTATAAAGACACAAGTTATATTCGTACAGCGCTTATTGCTCAACAA
ATGGGTCATAAGGTTTTTATTGTTATTGAAAAAAAATCTGAGTTGGACATTATTTTAAAGGAGTCTGCACGCCTTCAAAT
CAAACCAACATTAGGTGTGCGAATTCGGCTGGTCAGCAAGAGTGCTGGCAAGTGGGAAAATACCGGCGGGGTTAAATCAA
AGTTTGGACTAAATGCCAAACAGGTACTTGAACTGATTTTACAATTAAAAGCCAATGATATGCTGGATTGTTTGCAGCTA
ATGCACTGCCATTTAGGTTCACAAATTGCCAACATCCATGACATACGCCATTGCATGCAGGAAGTGGCGAGATACTATAT
TGAGCTACGTCAACTCAATGCTCCGATAGGTACCATCGATGTGGGTGGAGGTCTGAGTGTCGATTATGAGGGGACTCGAT
CCAATAAAGGATGCTCAATGAACTACAGTCTTGTTGAGTATGCTACGCACATCATGTTAGCTTTAAAACACTTATGTCAA
GAAGCTGAGATATCAGAGCCTGATCTTATCTCCGAATCAGGACGAGCATTAACAGCCCATCATGCTGTATTAATTTCTAA
TATTACGGATGTAGAGATTATCAATAAAGCGCCCGTTCTTCCTGAAATATCGGAAGATGATTCGCATGTCATTCGAGATA
TTTACGATACTTATCAAGCCATTACAGATAGCTCGCCCACTGAAATATATAATTACGCAGCTCATTCGCTTAATGAAGCG
CATTCCCTTTTCAAGCATGGGGTAATTAGCCTGCAGGAAAAGGCCAAGGTAGAAGCTTTTTATACTAATATTTGTATGGA
AATAAAAGATAAACTGGATGAAGAAAATCCAAGTGAAAAAGCTTTGCTAATGAGAATCAATGAATGCATGGCTGCCAAGA
TATTTTGTAATATCTCTTTTTTCCAATCTATTCCTGATGCTTGGGCTATTGGTCAGATTTTCCCGGTAGCCCCTATATCT
CAACTTAATAGAACACTTAGTATGCATAGTATCCTACAGGATTTAACCTGCGATTCAGATGGTACAATTAAGCAATACCC
TGGAAGTTCCTGCGTTACAACCACATTGATGCTCCCTTCATACGATATCAATAACCCTTATAACATCGGATTTTTCCTGG
TTGGTGCCTATCAGGAAATATTGGGTAATCTGCATAACTTGTTTGGAGATACCAATTCTCTAGATGTAAAGCTTTCTGAT
GATGGACAATTTGAGCTGGATGATTTAGTCAGCGGCGACACCGTAACAAACGTGTTGAATTTAGCCCATTTTGATACCAA
AAAGTTAATTCAATCTTATGAAAAGCAATTAATTAAATCTGAACTTCCTAAGGAAAAGGCACTCTCTTACTTAAACGAAT
TAAGAAGTATTTTTTCTCAATTAACTTACCTTGATGGAAATATAGCACAGTGA

Upstream 100 bases:

>100_bases
CGTGAATTGTGGGGGCGATTATTTCCATTTCCCCAACAACGAGAGCCTGAAACTTATCATGAATTAGTCAAATCCCGTTA
ATCCTCTTTGGAACGTTAGA

Downstream 100 bases:

>100_bases
ATATGAATACAGCACCCAAACAATATGGTTTTTATATGCCTGCTGAATGGTATCCTCATGAACGATGCTGGATGGCATGG
CCCTGTCACCATGAAACCTG

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MNNNTLSDDNLYNIENWGEGYFRINSKGNIEISKKPGKPGVELQTIVDAADRAGLHLPLLIRCSDILHDRVHRIYQAFTQ
AREDTCYAGNYQLVYPIKVNQEQSVVRELLKSPDNQIGLEAGSKPELMAVIGMLGDHQSTIVCNGYKDTSYIRTALIAQQ
MGHKVFIVIEKKSELDIILKESARLQIKPTLGVRIRLVSKSAGKWENTGGVKSKFGLNAKQVLELILQLKANDMLDCLQL
MHCHLGSQIANIHDIRHCMQEVARYYIELRQLNAPIGTIDVGGGLSVDYEGTRSNKGCSMNYSLVEYATHIMLALKHLCQ
EAEISEPDLISESGRALTAHHAVLISNITDVEIINKAPVLPEISEDDSHVIRDIYDTYQAITDSSPTEIYNYAAHSLNEA
HSLFKHGVISLQEKAKVEAFYTNICMEIKDKLDEENPSEKALLMRINECMAAKIFCNISFFQSIPDAWAIGQIFPVAPIS
QLNRTLSMHSILQDLTCDSDGTIKQYPGSSCVTTTLMLPSYDINNPYNIGFFLVGAYQEILGNLHNLFGDTNSLDVKLSD
DGQFELDDLVSGDTVTNVLNLAHFDTKKLIQSYEKQLIKSELPKEKALSYLNELRSIFSQLTYLDGNIAQ

Sequences:

>Translated_630_residues
MNNNTLSDDNLYNIENWGEGYFRINSKGNIEISKKPGKPGVELQTIVDAADRAGLHLPLLIRCSDILHDRVHRIYQAFTQ
AREDTCYAGNYQLVYPIKVNQEQSVVRELLKSPDNQIGLEAGSKPELMAVIGMLGDHQSTIVCNGYKDTSYIRTALIAQQ
MGHKVFIVIEKKSELDIILKESARLQIKPTLGVRIRLVSKSAGKWENTGGVKSKFGLNAKQVLELILQLKANDMLDCLQL
MHCHLGSQIANIHDIRHCMQEVARYYIELRQLNAPIGTIDVGGGLSVDYEGTRSNKGCSMNYSLVEYATHIMLALKHLCQ
EAEISEPDLISESGRALTAHHAVLISNITDVEIINKAPVLPEISEDDSHVIRDIYDTYQAITDSSPTEIYNYAAHSLNEA
HSLFKHGVISLQEKAKVEAFYTNICMEIKDKLDEENPSEKALLMRINECMAAKIFCNISFFQSIPDAWAIGQIFPVAPIS
QLNRTLSMHSILQDLTCDSDGTIKQYPGSSCVTTTLMLPSYDINNPYNIGFFLVGAYQEILGNLHNLFGDTNSLDVKLSD
DGQFELDDLVSGDTVTNVLNLAHFDTKKLIQSYEKQLIKSELPKEKALSYLNELRSIFSQLTYLDGNIAQ
>Mature_630_residues
MNNNTLSDDNLYNIENWGEGYFRINSKGNIEISKKPGKPGVELQTIVDAADRAGLHLPLLIRCSDILHDRVHRIYQAFTQ
AREDTCYAGNYQLVYPIKVNQEQSVVRELLKSPDNQIGLEAGSKPELMAVIGMLGDHQSTIVCNGYKDTSYIRTALIAQQ
MGHKVFIVIEKKSELDIILKESARLQIKPTLGVRIRLVSKSAGKWENTGGVKSKFGLNAKQVLELILQLKANDMLDCLQL
MHCHLGSQIANIHDIRHCMQEVARYYIELRQLNAPIGTIDVGGGLSVDYEGTRSNKGCSMNYSLVEYATHIMLALKHLCQ
EAEISEPDLISESGRALTAHHAVLISNITDVEIINKAPVLPEISEDDSHVIRDIYDTYQAITDSSPTEIYNYAAHSLNEA
HSLFKHGVISLQEKAKVEAFYTNICMEIKDKLDEENPSEKALLMRINECMAAKIFCNISFFQSIPDAWAIGQIFPVAPIS
QLNRTLSMHSILQDLTCDSDGTIKQYPGSSCVTTTLMLPSYDINNPYNIGFFLVGAYQEILGNLHNLFGDTNSLDVKLSD
DGQFELDDLVSGDTVTNVLNLAHFDTKKLIQSYEKQLIKSELPKEKALSYLNELRSIFSQLTYLDGNIAQ

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=620, Percent_Identity=45.4838709677419, Blast_Score=547, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 70424; Mature: 70424

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNTLSDDNLYNIENWGEGYFRINSKGNIEISKKPGKPGVELQTIVDAADRAGLHLPLL
CCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCHH
IRCSDILHDRVHRIYQAFTQAREDTCYAGNYQLVYPIKVNQEQSVVRELLKSPDNQIGLE
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEEEEEECCCHHHHHHHHHHCCCCCCCCC
AGSKPELMAVIGMLGDHQSTIVCNGYKDTSYIRTALIAQQMGHKVFIVIEKKSELDIILK
CCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCEEEEE
ESARLQIKPTLGVRIRLVSKSAGKWENTGGVKSKFGLNAKQVLELILQLKANDMLDCLQL
CCCCEEEEECCCEEEEEEECCCCCCCCCCCCCHHCCCCHHHHHHHHHHHCCCHHHHHHHH
MHCHLGSQIANIHDIRHCMQEVARYYIELRQLNAPIGTIDVGGGLSVDYEGTRSNKGCSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEECCCCCCCCCCCCC
NYSLVEYATHIMLALKHLCQEAEISEPDLISESGRALTAHHAVLISNITDVEIINKAPVL
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHEEEECCCCCEEEECCCCCC
PEISEDDSHVIRDIYDTYQAITDSSPTEIYNYAAHSLNEAHSLFKHGVISLQEKAKVEAF
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
YTNICMEIKDKLDEENPSEKALLMRINECMAAKIFCNISFFQSIPDAWAIGQIFPVAPIS
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEHHHHHHCCCHHHHCCCCCCCCHH
QLNRTLSMHSILQDLTCDSDGTIKQYPGSSCVTTTLMLPSYDINNPYNIGFFLVGAYQEI
HHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEEEECCCCCCCCCEEHEEEHHHHHHH
LGNLHNLFGDTNSLDVKLSDDGQFELDDLVSGDTVTNVLNLAHFDTKKLIQSYEKQLIKS
HHHHHHHCCCCCCEEEEECCCCCEEHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ELPKEKALSYLNELRSIFSQLTYLDGNIAQ
HCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNNNTLSDDNLYNIENWGEGYFRINSKGNIEISKKPGKPGVELQTIVDAADRAGLHLPLL
CCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCHH
IRCSDILHDRVHRIYQAFTQAREDTCYAGNYQLVYPIKVNQEQSVVRELLKSPDNQIGLE
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEEEEEECCCHHHHHHHHHHCCCCCCCCC
AGSKPELMAVIGMLGDHQSTIVCNGYKDTSYIRTALIAQQMGHKVFIVIEKKSELDIILK
CCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCEEEEE
ESARLQIKPTLGVRIRLVSKSAGKWENTGGVKSKFGLNAKQVLELILQLKANDMLDCLQL
CCCCEEEEECCCEEEEEEECCCCCCCCCCCCCHHCCCCHHHHHHHHHHHCCCHHHHHHHH
MHCHLGSQIANIHDIRHCMQEVARYYIELRQLNAPIGTIDVGGGLSVDYEGTRSNKGCSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEECCCCCCCCCCCCC
NYSLVEYATHIMLALKHLCQEAEISEPDLISESGRALTAHHAVLISNITDVEIINKAPVL
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHEEEECCCCCEEEECCCCCC
PEISEDDSHVIRDIYDTYQAITDSSPTEIYNYAAHSLNEAHSLFKHGVISLQEKAKVEAF
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
YTNICMEIKDKLDEENPSEKALLMRINECMAAKIFCNISFFQSIPDAWAIGQIFPVAPIS
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEHHHHHHCCCHHHHCCCCCCCCHH
QLNRTLSMHSILQDLTCDSDGTIKQYPGSSCVTTTLMLPSYDINNPYNIGFFLVGAYQEI
HHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEEEECCCCCCCCCEEHEEEHHHHHHH
LGNLHNLFGDTNSLDVKLSDDGQFELDDLVSGDTVTNVLNLAHFDTKKLIQSYEKQLIKS
HHHHHHHCCCCCCEEEEECCCCCEEHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ELPKEKALSYLNELRSIFSQLTYLDGNIAQ
HCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA