Click here to switch to the map view.

The map label for this gene is gntK [H]

Identifier: 52787964

GI number: 52787964

Start: 4132992

End: 4134533

Strand: Direct

Name: gntK [H]

Synonym: BLi04287

Alternate gene names: 52787964

Gene position: 4132992-4134533 (Clockwise)

Preceding gene: 52787963

Following gene: 52787965

Centisome position: 97.88

GC content: 49.68

Gene sequence:

>1542_bases
ATGACTAGTTATATGTTAGGCATAGATATCGGTACGACAAGCACGAAAGCGGTTTTATTCAGTGAAAAAGGGGACGTGAT
CCAAAAGGAAAGCATCGGCTACCCGCTTCACACGCCGGACATCTCGACCGCTGAACAAAACCCGGATGAGATCTTTCAGG
CCGTCATCCAGTCAACGGCGAAAATCATGCAGCAGCATCCCGACAAACAGCCGTCATTCATTTCATTCAGCAGTGCGATG
CACAGCGTGATTGCGATGGACGAAAACGACAAGCCGCTCACCTCCTGCATCACTTGGGCAGATAACAGAAGCGAAGGCTG
GGCTCATAAAATCAAAGAAGAAATGAACGGGCACAATATCTACAAACGGACGGGAACGCCGATTCACCCGATGACGCCGC
TAAGCAAAATCACGTGGATTGTGAACGAACATCCTGAAACCGCTGCCAAAGCGAAAAAATATATCGGAATCAAAGAATAT
ATTTTCAAAAAACTATTTGATCAATATGTCGTTGATCACTCATTAGCTTCGGCGATGGGAATGATGAATCTCAAAACCTT
GGCCTGGGACGAGGAAGCACTTGCGATTGCCGGCATCACGCCCGACCACTTATCAAAGCTCGTTCCGACAACAGCAATTT
TCCATAATTGCAATCCGGAACTGGCGGCGATGATGGGAATCGATCCGCAAACGCCGTTTGTCATCGGCGCAAGCGACGGC
GTGCTGTCCAACCTCGGCGTCAACGCGATTAAAAAAGGCGAAATCGCCGTCACCATCGGGACAAGCGGCGCGATTCGCAC
GATTATCGATGAGCCGCAAACCGATGAAAAAGGCAGAATCTTTTGCTATGCCTTAACTGAAAACCATTGGGTCATCGGCG
GGCCAGTCAACAACGGCGGGATCGTCCTTCGCTGGATCAGAGATGAATTTGCTTCATCAGAAATCGAAACCGCAAAACGC
CTCGGCATTGATCCATATGATGTCTTGACCAAAATTGCCGAACGCGTCAGACCGGGTGCCGACGGACTGCTGTTCCATCC
ATACCTCGCAGGCGAACGGGCGCCGCTCTGGAATCCGGATGTGCGCGGTTCATTCTTCGGCCTCACCATGTCCCATAAAA
AAGAACACATGATCCGCGCGGCATTGGAAGGGGTTATTTACAATCTGTACACCGTCTTCCTGGCGTTGACAGAATGCATG
GACGGTCCAGTTGCCCGAATTCAGGCGACCGGAGGCTTCGCAAGGTCTGATGTGTGGAGGCAAATGATGGCCGATATTTT
CGAATCGGAAGTCGTCGTGCCGGAAAGCTATGAAAGCTCTTGTCTCGGAGCCTGCATTTTGGGACTGTACGCGACGGGAA
AAATCGATTCGTTCGATGTCGTCTCCGACATGGTCGGAAGCACGCACAGACACGCGCCGAAAGAAGAATCGGCCAAAGAA
TACAGAAAATTAATGCCGATCTTTATCAACTTATCTCGAGCACTGGAAAACGAGTATACACAAATTGCAAATTATCAAAG
AAGCTTAACCAGCAAAAAATAG

Upstream 100 bases:

>100_bases
ATGCTTAAATCCCTACATCAAAATTTCGATGACGTACAAGGTAAAGTTGAAGATCTATGGCTGTCGCAACAAATGCTGGC
GAAAGGAGCCGAACAACAAA

Downstream 100 bases:

>100_bases
GGGAAGAATTGGAGGCGTTATCATGCCATTATTAATCGTAGCAATCGGGATTGTCGCATTATTGCTTTTGATTATGGGGT
TAAAACTGAATACGTTTGTT

Product: GntK

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MTSYMLGIDIGTTSTKAVLFSEKGDVIQKESIGYPLHTPDISTAEQNPDEIFQAVIQSTAKIMQQHPDKQPSFISFSSAM
HSVIAMDENDKPLTSCITWADNRSEGWAHKIKEEMNGHNIYKRTGTPIHPMTPLSKITWIVNEHPETAAKAKKYIGIKEY
IFKKLFDQYVVDHSLASAMGMMNLKTLAWDEEALAIAGITPDHLSKLVPTTAIFHNCNPELAAMMGIDPQTPFVIGASDG
VLSNLGVNAIKKGEIAVTIGTSGAIRTIIDEPQTDEKGRIFCYALTENHWVIGGPVNNGGIVLRWIRDEFASSEIETAKR
LGIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECM
DGPVARIQATGGFARSDVWRQMMADIFESEVVVPESYESSCLGACILGLYATGKIDSFDVVSDMVGSTHRHAPKEESAKE
YRKLMPIFINLSRALENEYTQIANYQRSLTSKK

Sequences:

>Translated_513_residues
MTSYMLGIDIGTTSTKAVLFSEKGDVIQKESIGYPLHTPDISTAEQNPDEIFQAVIQSTAKIMQQHPDKQPSFISFSSAM
HSVIAMDENDKPLTSCITWADNRSEGWAHKIKEEMNGHNIYKRTGTPIHPMTPLSKITWIVNEHPETAAKAKKYIGIKEY
IFKKLFDQYVVDHSLASAMGMMNLKTLAWDEEALAIAGITPDHLSKLVPTTAIFHNCNPELAAMMGIDPQTPFVIGASDG
VLSNLGVNAIKKGEIAVTIGTSGAIRTIIDEPQTDEKGRIFCYALTENHWVIGGPVNNGGIVLRWIRDEFASSEIETAKR
LGIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECM
DGPVARIQATGGFARSDVWRQMMADIFESEVVVPESYESSCLGACILGLYATGKIDSFDVVSDMVGSTHRHAPKEESAKE
YRKLMPIFINLSRALENEYTQIANYQRSLTSKK
>Mature_512_residues
TSYMLGIDIGTTSTKAVLFSEKGDVIQKESIGYPLHTPDISTAEQNPDEIFQAVIQSTAKIMQQHPDKQPSFISFSSAMH
SVIAMDENDKPLTSCITWADNRSEGWAHKIKEEMNGHNIYKRTGTPIHPMTPLSKITWIVNEHPETAAKAKKYIGIKEYI
FKKLFDQYVVDHSLASAMGMMNLKTLAWDEEALAIAGITPDHLSKLVPTTAIFHNCNPELAAMMGIDPQTPFVIGASDGV
LSNLGVNAIKKGEIAVTIGTSGAIRTIIDEPQTDEKGRIFCYALTENHWVIGGPVNNGGIVLRWIRDEFASSEIETAKRL
GIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMD
GPVARIQATGGFARSDVWRQMMADIFESEVVVPESYESSCLGACILGLYATGKIDSFDVVSDMVGSTHRHAPKEESAKEY
RKLMPIFINLSRALENEYTQIANYQRSLTSKK

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=466, Percent_Identity=22.9613733905579, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI189409120, Length=466, Percent_Identity=23.175965665236, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI4504007, Length=466, Percent_Identity=23.175965665236, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI41393575, Length=448, Percent_Identity=22.7678571428571, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI88196792, Length=483, Percent_Identity=22.360248447205, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI18860918, Length=418, Percent_Identity=21.5311004784689, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1789987, Length=425, Percent_Identity=26.1176470588235, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1787789, Length=509, Percent_Identity=24.75442043222, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1790361, Length=493, Percent_Identity=23.9350912778905, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790005, Length=521, Percent_Identity=24.3761996161228, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1789168, Length=470, Percent_Identity=20.8510638297872, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789138, Length=503, Percent_Identity=24.0556660039761, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17535599, Length=477, Percent_Identity=24.1090146750524, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321755, Length=434, Percent_Identity=23.963133640553, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17864214, Length=490, Percent_Identity=23.8775510204082, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24655555, Length=436, Percent_Identity=24.3119266055046, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24655560, Length=436, Percent_Identity=24.3119266055046, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24655570, Length=436, Percent_Identity=24.3119266055046, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24655574, Length=436, Percent_Identity=24.3119266055046, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24655565, Length=436, Percent_Identity=24.3119266055046, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24654573, Length=408, Percent_Identity=24.2647058823529, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24656367, Length=482, Percent_Identity=21.3692946058091, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21357867, Length=497, Percent_Identity=21.7303822937626, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24656372, Length=301, Percent_Identity=23.9202657807309, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 56824; Mature: 56692

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYMLGIDIGTTSTKAVLFSEKGDVIQKESIGYPLHTPDISTAEQNPDEIFQAVIQSTA
CCCEEEEEEECCCCCEEEEEECCCCEEEHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KIMQQHPDKQPSFISFSSAMHSVIAMDENDKPLTSCITWADNRSEGWAHKIKEEMNGHNI
HHHHHCCCCCCCEEEHHHHHHHHEEECCCCCCHHHHHEECCCCCCHHHHHHHHHCCCCCE
YKRTGTPIHPMTPLSKITWIVNEHPETAAKAKKYIGIKEYIFKKLFDQYVVDHSLASAMG
EECCCCCCCCCCCHHHEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MMNLKTLAWDEEALAIAGITPDHLSKLVPTTAIFHNCNPELAAMMGIDPQTPFVIGASDG
HHHHHHEEECCCCEEEECCCHHHHHHHCCHHHHHHCCCHHHHHEECCCCCCCEEEECCCC
VLSNLGVNAIKKGEIAVTIGTSGAIRTIIDEPQTDEKGRIFCYALTENHWVIGGPVNNGG
HHHHCCCCCEECCCEEEEECCCCCCHHHHCCCCCCCCCCEEEEEEECCCEEEECCCCCCC
IVLRWIRDEFASSEIETAKRLGIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPD
EEEEEEHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
VRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVARIQATGGFARSDVWR
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
QMMADIFESEVVVPESYESSCLGACILGLYATGKIDSFDVVSDMVGSTHRHAPKEESAKE
HHHHHHHHCCEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHCCCCCHHHHHH
YRKLMPIFINLSRALENEYTQIANYQRSLTSKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSYMLGIDIGTTSTKAVLFSEKGDVIQKESIGYPLHTPDISTAEQNPDEIFQAVIQSTA
CCEEEEEEECCCCCEEEEEECCCCEEEHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
KIMQQHPDKQPSFISFSSAMHSVIAMDENDKPLTSCITWADNRSEGWAHKIKEEMNGHNI
HHHHHCCCCCCCEEEHHHHHHHHEEECCCCCCHHHHHEECCCCCCHHHHHHHHHCCCCCE
YKRTGTPIHPMTPLSKITWIVNEHPETAAKAKKYIGIKEYIFKKLFDQYVVDHSLASAMG
EECCCCCCCCCCCHHHEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MMNLKTLAWDEEALAIAGITPDHLSKLVPTTAIFHNCNPELAAMMGIDPQTPFVIGASDG
HHHHHHEEECCCCEEEECCCHHHHHHHCCHHHHHHCCCHHHHHEECCCCCCCEEEECCCC
VLSNLGVNAIKKGEIAVTIGTSGAIRTIIDEPQTDEKGRIFCYALTENHWVIGGPVNNGG
HHHHCCCCCEECCCEEEEECCCCCCHHHHCCCCCCCCCCEEEEEEECCCEEEECCCCCCC
IVLRWIRDEFASSEIETAKRLGIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPD
EEEEEEHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
VRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVARIQATGGFARSDVWR
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
QMMADIFESEVVVPESYESSCLGACILGLYATGKIDSFDVVSDMVGSTHRHAPKEESAKE
HHHHHHHHCCEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHCCCCCHHHHHH
YRKLMPIFINLSRALENEYTQIANYQRSLTSKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8535972 [H]