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The map label for this gene is yxeB [H]

Identifier: 52787939

GI number: 52787939

Start: 4103070

End: 4104029

Strand: Direct

Name: yxeB [H]

Synonym: BLi04262

Alternate gene names: 52787939

Gene position: 4103070-4104029 (Clockwise)

Preceding gene: 52787934

Following gene: 52787941

Centisome position: 97.17

GC content: 45.1

Gene sequence:

>960_bases
GTGAAAAAGAACTTATTGATAATCGGTTTAGTTATGCTGTTGTGTATAGTGGTCAGCGCCTGCGGAAGCGGCAATGCGTC
AAACGGTAGCAAAGAAAAAGCGGCTGAAGAAACGACAAGAACATATCAATCAACGCGTGGAAGCGTGAAGATTCCAACAC
ATCCAAAGCGCATCGTGACAGACTTTTATGCCGGTGAACTGTTCACGGTCGGCGCCAATGTCGTCGGCTCCGGCTCGTGG
TCTTTCTCCAATCCATTTTTAAAGGACCGTATGAAAGATGTAACGGATTTAGGCGACCCGATTAATGTGGAAAAAGTCAT
GAAGCTGAAGCCTGATTTAATTGTCGTGATGAACGATGATAATTACGACAAACTGTCCAAAATCGCACCGACTGTTGTGA
TTCCTTATAACACGGCGAAAAATGTTCAGGAAACTGTTAAGATGTTCGGCGACATTGCAGGAGCTAAAGAAGAAGCTGAA
CAATTCCTTGCCGATTTCGACCGGAAATCGAAAGCAGCGAGGAAAAAAATCGCTCAAGTCGTCGACAAAAATGCTACTTT
CGGTATTTATGAAAACACAGAAAAAGGCCAATTCTGGGTGTTCAATGACAACGGCGGCCGCGGAGGCCAAGCCGTGTACA
ACGCGCTCGGCTTAAAGGCGCCTGAAAAGATTCAAAAAGACATCTTCAAAAAAGGCGAAATCAAAGAACTTTCCTTGGAA
GTCGTACCTGAATATGCAGCAGACTACATGTTCGTGACAGACTATAACCCGAACGGCGACAGCAAAACGCTGGACAAGCT
GAAGCAGTCTTCCATTTGGAAAAACCTTGACGCCGTCAAAAACAACCGTGTCTTTATCAACGACTTTGACACGTTCTATC
CGTACGATCCGATCTCTGTCAGCAAACAGGTTGATTTGATTACGGAGATGCTGGTGAAGCGCGAAAAGGAGAATAAGTAA

Upstream 100 bases:

>100_bases
TGATAGACGAGAGAGGGATTGATCTGCTATATTTACATTGATAATGCGAATCATTATCACTTAGGAAATGTCATATGTTT
CACATCAACAGGAGGGTCAA

Downstream 100 bases:

>100_bases
AAAAGCTGGAATTTCCAGCTTTTTTTATTGTTTTCTTTCTTGAATGCTTGAAAACCTAAAAGCAAATTGAAAGATCAAAT
AGAAAGGAATGTAGAAAAGA

Product: YxeB

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein yxeB; Iron(III)-hydroxamate-binding protein yxeB [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MKKNLLIIGLVMLLCIVVSACGSGNASNGSKEKAAEETTRTYQSTRGSVKIPTHPKRIVTDFYAGELFTVGANVVGSGSW
SFSNPFLKDRMKDVTDLGDPINVEKVMKLKPDLIVVMNDDNYDKLSKIAPTVVIPYNTAKNVQETVKMFGDIAGAKEEAE
QFLADFDRKSKAARKKIAQVVDKNATFGIYENTEKGQFWVFNDNGGRGGQAVYNALGLKAPEKIQKDIFKKGEIKELSLE
VVPEYAADYMFVTDYNPNGDSKTLDKLKQSSIWKNLDAVKNNRVFINDFDTFYPYDPISVSKQVDLITEMLVKREKENK

Sequences:

>Translated_319_residues
MKKNLLIIGLVMLLCIVVSACGSGNASNGSKEKAAEETTRTYQSTRGSVKIPTHPKRIVTDFYAGELFTVGANVVGSGSW
SFSNPFLKDRMKDVTDLGDPINVEKVMKLKPDLIVVMNDDNYDKLSKIAPTVVIPYNTAKNVQETVKMFGDIAGAKEEAE
QFLADFDRKSKAARKKIAQVVDKNATFGIYENTEKGQFWVFNDNGGRGGQAVYNALGLKAPEKIQKDIFKKGEIKELSLE
VVPEYAADYMFVTDYNPNGDSKTLDKLKQSSIWKNLDAVKNNRVFINDFDTFYPYDPISVSKQVDLITEMLVKREKENK
>Mature_319_residues
MKKNLLIIGLVMLLCIVVSACGSGNASNGSKEKAAEETTRTYQSTRGSVKIPTHPKRIVTDFYAGELFTVGANVVGSGSW
SFSNPFLKDRMKDVTDLGDPINVEKVMKLKPDLIVVMNDDNYDKLSKIAPTVVIPYNTAKNVQETVKMFGDIAGAKEEAE
QFLADFDRKSKAARKKIAQVVDKNATFGIYENTEKGQFWVFNDNGGRGGQAVYNALGLKAPEKIQKDIFKKGEIKELSLE
VVPEYAADYMFVTDYNPNGDSKTLDKLKQSSIWKNLDAVKNNRVFINDFDTFYPYDPISVSKQVDLITEMLVKREKENK

Specific function: Part of the ABC transporter complex fhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Partially required for the transport of desferrioxamine [H]

COG id: COG0614

COG function: function code P; ABC-type Fe3+-hydroxamate transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786807, Length=282, Percent_Identity=25.531914893617, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 35614; Mature: 35614

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNLLIIGLVMLLCIVVSACGSGNASNGSKEKAAEETTRTYQSTRGSVKIPTHPKRIVT
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCHHHHH
DFYAGELFTVGANVVGSGSWSFSNPFLKDRMKDVTDLGDPINVEKVMKLKPDLIVVMNDD
HHHCCCEEEECCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCC
NYDKLSKIAPTVVIPYNTAKNVQETVKMFGDIAGAKEEAEQFLADFDRKSKAARKKIAQV
CHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VDKNATFGIYENTEKGQFWVFNDNGGRGGQAVYNALGLKAPEKIQKDIFKKGEIKELSLE
HCCCCEEEEEECCCCCEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHH
VVPEYAADYMFVTDYNPNGDSKTLDKLKQSSIWKNLDAVKNNRVFINDFDTFYPYDPISV
CCHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCH
SKQVDLITEMLVKREKENK
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKNLLIIGLVMLLCIVVSACGSGNASNGSKEKAAEETTRTYQSTRGSVKIPTHPKRIVT
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCHHHHH
DFYAGELFTVGANVVGSGSWSFSNPFLKDRMKDVTDLGDPINVEKVMKLKPDLIVVMNDD
HHHCCCEEEECCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCC
NYDKLSKIAPTVVIPYNTAKNVQETVKMFGDIAGAKEEAEQFLADFDRKSKAARKKIAQV
CHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VDKNATFGIYENTEKGQFWVFNDNGGRGGQAVYNALGLKAPEKIQKDIFKKGEIKELSLE
HCCCCEEEEEECCCCCEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHH
VVPEYAADYMFVTDYNPNGDSKTLDKLKQSSIWKNLDAVKNNRVFINDFDTFYPYDPISV
CCHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCH
SKQVDLITEMLVKREKENK
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8867804; 9384377 [H]