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The map label for this gene is scrR [H]

Identifier: 52787860

GI number: 52787860

Start: 4011554

End: 4012528

Strand: Direct

Name: scrR [H]

Synonym: BLi04183

Alternate gene names: 52787860

Gene position: 4011554-4012528 (Clockwise)

Preceding gene: 52787854

Following gene: 52787861

Centisome position: 95.0

GC content: 44.92

Gene sequence:

>975_bases
ATGAAGCCTAGCATTCACGACGTTGCAAAAAAAGCGGGAGTTTCACCAACAACCGTATCGCGGGTATTAAATAACCGCGG
CTATATTAGTGAAAAAACAAAAGAAAAAGTCTATAAAGCGATGGAAGAAATCAATTACTTTCCAAACGATTTGGCCCGCT
CTTTATTTCGTAAACGAACTCATTTAATAGGGCTCATCATCCCTAACTCCAGCAACCCGTTTTTCGGCGAACTGGCCTTT
CATATTGAGAGCATCTGCGCTGCCATGGGCTACAAACTGCTGCTTTGCAACAGCTTAAACCGCAAAGACAAAGAAGAAAA
ATACTTGGAAATGCTGATGCGAAATCAAGTGGACGGCGTCATCGCCGTGACTTACAACAGGGGAATTTTAAATTATCATC
GGCAAAACCTGCCGATTGTCGCCATCGACCATTACTTGTCGGAAACGATTCCCGTCATCGGCTCTGATAACTATGACGGA
GGAAGAAAAGCGACAGAACTGTTAATTGCAAAAGGCTGCCGGCACATCATCCATATCAACGGACCAATTGAGCTGAAAAC
ACCGGCAAATCTTAGAAGAAAAGCATATGAAGATGTGATGCGACAACACGGGAGACAGCCGATTACATATGAAGTTCCCT
TTCATCAAAATTACCGGGAAATCATTTCAAAACTGTTTGATGAACAGCCTGCAGCTGACGGCATTTTTGCCAGTGATGAC
CTCATGGCCGCTACAGTCATCACCGAAGCAAAAAAACGCAGAAAAGACATTCCCGGGCAATTAAAGGTGATCGGCTACGA
CGGAACGGAAGCGGTTCAGTCCATTCTCCCGGAATTGACAACCATCCAGCAGCCGATCGAACTCATTTCCAAGACGGCCA
TTGAGATTTTGTCCAAAGCCATTGAAGGCGAATTCGATGATTTGCCGCTGGAAACCTATTTGCCCGTACAGCTTTTAGAA
GGAGAGACGACTTAA

Upstream 100 bases:

>100_bases
AATCATGGCATTTTCTTGCACATATCGGCCCGATTCTCTAAAATAAGTGCGTGACGAGAATTGTAAGCCATTTCAGTAAA
AATAGCAGGGGGAAAAGGGA

Downstream 100 bases:

>100_bases
AATAACGGGACAAAAAAAGGAGACATTGACGTCTCCTTTCTCCATACATATCCTGATCTATCCAATTATAAAAAAGATAA
AATTTACATTGCTCACCTAA

Product: hypothetical protein

Products: NA

Alternate protein names: Scr operon regulatory protein [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKPSIHDVAKKAGVSPTTVSRVLNNRGYISEKTKEKVYKAMEEINYFPNDLARSLFRKRTHLIGLIIPNSSNPFFGELAF
HIESICAAMGYKLLLCNSLNRKDKEEKYLEMLMRNQVDGVIAVTYNRGILNYHRQNLPIVAIDHYLSETIPVIGSDNYDG
GRKATELLIAKGCRHIIHINGPIELKTPANLRRKAYEDVMRQHGRQPITYEVPFHQNYREIISKLFDEQPAADGIFASDD
LMAATVITEAKKRRKDIPGQLKVIGYDGTEAVQSILPELTTIQQPIELISKTAIEILSKAIEGEFDDLPLETYLPVQLLE
GETT

Sequences:

>Translated_324_residues
MKPSIHDVAKKAGVSPTTVSRVLNNRGYISEKTKEKVYKAMEEINYFPNDLARSLFRKRTHLIGLIIPNSSNPFFGELAF
HIESICAAMGYKLLLCNSLNRKDKEEKYLEMLMRNQVDGVIAVTYNRGILNYHRQNLPIVAIDHYLSETIPVIGSDNYDG
GRKATELLIAKGCRHIIHINGPIELKTPANLRRKAYEDVMRQHGRQPITYEVPFHQNYREIISKLFDEQPAADGIFASDD
LMAATVITEAKKRRKDIPGQLKVIGYDGTEAVQSILPELTTIQQPIELISKTAIEILSKAIEGEFDDLPLETYLPVQLLE
GETT
>Mature_324_residues
MKPSIHDVAKKAGVSPTTVSRVLNNRGYISEKTKEKVYKAMEEINYFPNDLARSLFRKRTHLIGLIIPNSSNPFFGELAF
HIESICAAMGYKLLLCNSLNRKDKEEKYLEMLMRNQVDGVIAVTYNRGILNYHRQNLPIVAIDHYLSETIPVIGSDNYDG
GRKATELLIAKGCRHIIHINGPIELKTPANLRRKAYEDVMRQHGRQPITYEVPFHQNYREIISKLFDEQPAADGIFASDD
LMAATVITEAKKRRKDIPGQLKVIGYDGTEAVQSILPELTTIQQPIELISKTAIEILSKAIEGEFDDLPLETYLPVQLLE
GETT

Specific function: Negative regulator of scrB expression [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=305, Percent_Identity=35.0819672131148, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1787948, Length=305, Percent_Identity=30.4918032786885, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI48994940, Length=310, Percent_Identity=27.741935483871, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1790369, Length=314, Percent_Identity=27.7070063694268, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788474, Length=325, Percent_Identity=27.3846153846154, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1789068, Length=300, Percent_Identity=29, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787580, Length=318, Percent_Identity=26.7295597484277, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789202, Length=292, Percent_Identity=28.4246575342466, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790715, Length=307, Percent_Identity=26.0586319218241, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786540, Length=355, Percent_Identity=30.1408450704225, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786268, Length=316, Percent_Identity=26.5822784810127, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787906, Length=242, Percent_Identity=28.5123966942149, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790689, Length=287, Percent_Identity=22.9965156794425, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36623; Mature: 36623

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPSIHDVAKKAGVSPTTVSRVLNNRGYISEKTKEKVYKAMEEINYFPNDLARSLFRKRT
CCCCHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
HLIGLIIPNSSNPFFGELAFHIESICAAMGYKLLLCNSLNRKDKEEKYLEMLMRNQVDGV
HEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHEECCCCCCCCHHHHHHHHHHHHCCCCE
IAVTYNRGILNYHRQNLPIVAIDHYLSETIPVIGSDNYDGGRKATELLIAKGCRHIIHIN
EEEEECCCHHHHHHCCCCEEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEC
GPIELKTPANLRRKAYEDVMRQHGRQPITYEVPFHQNYREIISKLFDEQPAADGIFASDD
CCEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCC
LMAATVITEAKKRRKDIPGQLKVIGYDGTEAVQSILPELTTIQQPIELISKTAIEILSKA
HHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEGEFDDLPLETYLPVQLLEGETT
HCCCCCCCCCCCCCCCEEECCCCC
>Mature Secondary Structure
MKPSIHDVAKKAGVSPTTVSRVLNNRGYISEKTKEKVYKAMEEINYFPNDLARSLFRKRT
CCCCHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
HLIGLIIPNSSNPFFGELAFHIESICAAMGYKLLLCNSLNRKDKEEKYLEMLMRNQVDGV
HEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHEECCCCCCCCHHHHHHHHHHHHCCCCE
IAVTYNRGILNYHRQNLPIVAIDHYLSETIPVIGSDNYDGGRKATELLIAKGCRHIIHIN
EEEEECCCHHHHHHCCCCEEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEC
GPIELKTPANLRRKAYEDVMRQHGRQPITYEVPFHQNYREIISKLFDEQPAADGIFASDD
CCEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCC
LMAATVITEAKKRRKDIPGQLKVIGYDGTEAVQSILPELTTIQQPIELISKTAIEILSKA
HHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEGEFDDLPLETYLPVQLLEGETT
HCCCCCCCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA