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The map label for this gene is kdgR [H]

Identifier: 52787750

GI number: 52787750

Start: 3897857

End: 3898615

Strand: Reverse

Name: kdgR [H]

Synonym: BLi04073

Alternate gene names: 52787750

Gene position: 3898615-3897857 (Counterclockwise)

Preceding gene: 52787752

Following gene: 52787749

Centisome position: 92.33

GC content: 49.54

Gene sequence:

>759_bases
ATGTCAGTAAAATCCGCGGTACGTGTTGTACGTATATTTGAATTGCTGTCAAATCATCCGGATGGATTAACCGTAAAGGA
AATCAGCAAAGAACTTTCGCTGCCTCAGAGCAGTACATTCAATTTGGCCGCTACACTTTTGGATGAAGGTTACCTTCAGC
AGGATGCTGTCAAGCGTTACAGGCTGGGGGCAAAATTGATTCAAGTTGGAACCGCTGCCATGGAGTCGATAGACATTTCA
TCGCAGGGCGTTCCTTTTTTAAAACAGCTGATGGACGGCGTTCAGGAAACGGTGTTTATGGCCGTTCTATCCGATGATCA
GCTCGTCTACATCGCAAAAATCGATAACAACAGGTCAATCAGAACAACCGCACAGCCCGGCTCGCGCAAACCGCTTTATT
GCACCGGGCTTGGCAAGGCATTTTTGGCATTCATGCCGGAGGACAAAAGGGAAGGGCTGCTCGACCGCATGGAGTTTATC
CGGTTTACCGGGCATACCATCACTGCCAGAGAAGAGCTGGAAAAGCAGCTGCAGACATTTTTGGAACAGGGATATGCCGT
TGACAATGAAGAAAATGAAGAAGGTTTGTTTTGTCTGGCGGCGCCTGTCTATGGTCCGGATGGCGTGATGAAGGCGGCGA
TCAGCACCGCCGGGCCAAAGGAGCGCATGCTCGCAAGAAAGGCCGTTATCGTTGAGCAGCTGCTTCACACAGCCGGAAAA
ATTACAGAAAGCATTGGCGGATATAGAAAGCCGCTTTAG

Upstream 100 bases:

>100_bases
TTTGATAGGATGGTTGACGTGAGCCTTCTTTCTGTTTAGAATACGTCCGAATTATCAGGATCCTGATTTTGAATCACATA
TGTGAATTTTGGAGGGTGTC

Downstream 100 bases:

>100_bases
CAAAGGAGAGAGTTCTGATGGATGTTATTAGCATAGGAGAGACAATGGCGCTGTTCACTCCGAATGAAGACGGCCCTCTC
AGATACGCAAGAAACTATCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSVKSAVRVVRIFELLSNHPDGLTVKEISKELSLPQSSTFNLAATLLDEGYLQQDAVKRYRLGAKLIQVGTAAMESIDIS
SQGVPFLKQLMDGVQETVFMAVLSDDQLVYIAKIDNNRSIRTTAQPGSRKPLYCTGLGKAFLAFMPEDKREGLLDRMEFI
RFTGHTITAREELEKQLQTFLEQGYAVDNEENEEGLFCLAAPVYGPDGVMKAAISTAGPKERMLARKAVIVEQLLHTAGK
ITESIGGYRKPL

Sequences:

>Translated_252_residues
MSVKSAVRVVRIFELLSNHPDGLTVKEISKELSLPQSSTFNLAATLLDEGYLQQDAVKRYRLGAKLIQVGTAAMESIDIS
SQGVPFLKQLMDGVQETVFMAVLSDDQLVYIAKIDNNRSIRTTAQPGSRKPLYCTGLGKAFLAFMPEDKREGLLDRMEFI
RFTGHTITAREELEKQLQTFLEQGYAVDNEENEEGLFCLAAPVYGPDGVMKAAISTAGPKERMLARKAVIVEQLLHTAGK
ITESIGGYRKPL
>Mature_251_residues
SVKSAVRVVRIFELLSNHPDGLTVKEISKELSLPQSSTFNLAATLLDEGYLQQDAVKRYRLGAKLIQVGTAAMESIDISS
QGVPFLKQLMDGVQETVFMAVLSDDQLVYIAKIDNNRSIRTTAQPGSRKPLYCTGLGKAFLAFMPEDKREGLLDRMEFIR
FTGHTITAREELEKQLQTFLEQGYAVDNEENEEGLFCLAAPVYGPDGVMKAAISTAGPKERMLARKAVIVEQLLHTAGKI
TESIGGYRKPL

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=253, Percent_Identity=32.8063241106719, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1786468, Length=222, Percent_Identity=32.4324324324324, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082359, Length=251, Percent_Identity=29.8804780876494, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786715, Length=246, Percent_Identity=31.7073170731707, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789999, Length=224, Percent_Identity=31.6964285714286, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1788581, Length=218, Percent_Identity=25.6880733944954, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1790752, Length=193, Percent_Identity=26.9430051813472, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27844; Mature: 27712

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKSAVRVVRIFELLSNHPDGLTVKEISKELSLPQSSTFNLAATLLDEGYLQQDAVKRY
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHH
RLGAKLIQVGTAAMESIDISSQGVPFLKQLMDGVQETVFMAVLSDDQLVYIAKIDNNRSI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCEEEEEEECCCCCE
RTTAQPGSRKPLYCTGLGKAFLAFMPEDKREGLLDRMEFIRFTGHTITAREELEKQLQTF
EECCCCCCCCCEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHH
LEQGYAVDNEENEEGLFCLAAPVYGPDGVMKAAISTAGPKERMLARKAVIVEQLLHTAGK
HHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ITESIGGYRKPL
HHHHHCCCCCCC
>Mature Secondary Structure 
SVKSAVRVVRIFELLSNHPDGLTVKEISKELSLPQSSTFNLAATLLDEGYLQQDAVKRY
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHH
RLGAKLIQVGTAAMESIDISSQGVPFLKQLMDGVQETVFMAVLSDDQLVYIAKIDNNRSI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCEEEEEEECCCCCE
RTTAQPGSRKPLYCTGLGKAFLAFMPEDKREGLLDRMEFIRFTGHTITAREELEKQLQTF
EECCCCCCCCCEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHH
LEQGYAVDNEENEEGLFCLAAPVYGPDGVMKAAISTAGPKERMLARKAVIVEQLLHTAGK
HHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ITESIGGYRKPL
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]