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The map label for this gene is ywcF [H]

Identifier: 52787702

GI number: 52787702

Start: 3850476

End: 3851714

Strand: Reverse

Name: ywcF [H]

Synonym: BLi04025

Alternate gene names: 52787702

Gene position: 3851714-3850476 (Counterclockwise)

Preceding gene: 52787704

Following gene: 52787701

Centisome position: 91.22

GC content: 44.55

Gene sequence:

>1239_bases
ATGCCGTCTTCCTGCATTAATTCATTGTGTCATATTATAAGGGCGGGATTTCGAATGAGTCAGAAAAAGAATATTACAAA
TCCCTTTTACCAGGGGGATTTGATTTTTGTCTATATTGTCTTTTTTATCATAAGCGTTGTGGCTGTGTACGCTGCTCAGC
AGTTTAATCAATATAATGAACCCTTTGCGATGAAACAGTCCCTTTACTATTTACTGGGGGCCTTCATCATCATCGTGTTT
CTTTATTTTGATTTGGAGCAGCTTGAAAAGCTCAGCTTTTATTTCTATCTGCTCGGCATTTTGATGCTGATCGTGTTAAA
GTTCAGTCCGGCATATATCGGATCATACAGGTTTGCGCCGGTCATCAACGGTGCCAAAAGCTGGTTTATGCTTCCCGGGT
TTACGCTGCAGCCGTCGGAATTTATGAAAATCGGGCTGATCATGTACTTGGCTTCCTTCATGTCTAAAAACGGCCCTGTC
GGCAAGCGTACGTTGAAAGAAGACTGGATTTTTCTGCTGAAAATCGCCGGTATCATCATTGTTCCGTTCGGCTTGATTTT
AGAGCAGGATACGGGTACAGCCGGGATCGTCGCGTTTGTGATCCTTGTGATGGTATTCCTGTCGGGCGTGAACTGGAAAT
TGATCTCTCTTATCTTCGGAACGGGTCTTGCAGCCGTTGCTTTGATTTTATATGTCATCATCAAATTTCCCGATGTTGCG
GGAGCGCTCGGGGTTGAACAATACCAAATCAACCGCGTTATGACCTGGGTCAATCCGAGCGAACAGAATGCCGACGATAA
AATGCAGGTCGAAAGGGCGCAAATGGCGATCGGTTCAGGAAAAGTATTCGGAAATGGTGTAAGCGATCTTCAAGTCTATG
TACCTGAGGCGCAAACAGACTTTATTTTTGCCGTCATTGGCGAGAGTTTCGGGTTTGTCGGATGCACTTTTGTTGTCATT
ATGTTTTTCTTCTTAATTTACCGGCTTGTCGTGCTCATCGACCGAATACATCCGTTCAGCAGGTTTGCCTCATTTTTCTG
TGCGGGCTTTACCGCTTTAATTGTCATTCATACCTTTCAAAATATCGGAATGAATATCGGCATTATGCCCGTGACCGGCG
TCCCACTGCTTTTGGTCAGCTATGGGGGCAGCTCAGTCGTAGCAACCTTGCTCGGCTTCGCGGTTGTCTACAATTCAAGC
TGCCAGTTAACAAAGTATCAAAGCTATATGTTCAAATAA

Upstream 100 bases:

>100_bases
CAATAGTTGGAAAAATCCTTTAAAATAGAATAGGAATTTGTTCGCAATAAAATCGAAACATTTTGTTCTTTTGTACGTCA
TATCATTTGTGAGGAAGCGG

Downstream 100 bases:

>100_bases
CAGCCTGATGTATGCGGGCTGTTATTTTATTCACCCTTTTTCGCAATGTGAACGGTTGTTCATGCTATAATGAAAGTTAG
TGCTTTTGATGAAGAAATAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MPSSCINSLCHIIRAGFRMSQKKNITNPFYQGDLIFVYIVFFIISVVAVYAAQQFNQYNEPFAMKQSLYYLLGAFIIIVF
LYFDLEQLEKLSFYFYLLGILMLIVLKFSPAYIGSYRFAPVINGAKSWFMLPGFTLQPSEFMKIGLIMYLASFMSKNGPV
GKRTLKEDWIFLLKIAGIIIVPFGLILEQDTGTAGIVAFVILVMVFLSGVNWKLISLIFGTGLAAVALILYVIIKFPDVA
GALGVEQYQINRVMTWVNPSEQNADDKMQVERAQMAIGSGKVFGNGVSDLQVYVPEAQTDFIFAVIGESFGFVGCTFVVI
MFFFLIYRLVVLIDRIHPFSRFASFFCAGFTALIVIHTFQNIGMNIGIMPVTGVPLLLVSYGGSSVVATLLGFAVVYNSS
CQLTKYQSYMFK

Sequences:

>Translated_412_residues
MPSSCINSLCHIIRAGFRMSQKKNITNPFYQGDLIFVYIVFFIISVVAVYAAQQFNQYNEPFAMKQSLYYLLGAFIIIVF
LYFDLEQLEKLSFYFYLLGILMLIVLKFSPAYIGSYRFAPVINGAKSWFMLPGFTLQPSEFMKIGLIMYLASFMSKNGPV
GKRTLKEDWIFLLKIAGIIIVPFGLILEQDTGTAGIVAFVILVMVFLSGVNWKLISLIFGTGLAAVALILYVIIKFPDVA
GALGVEQYQINRVMTWVNPSEQNADDKMQVERAQMAIGSGKVFGNGVSDLQVYVPEAQTDFIFAVIGESFGFVGCTFVVI
MFFFLIYRLVVLIDRIHPFSRFASFFCAGFTALIVIHTFQNIGMNIGIMPVTGVPLLLVSYGGSSVVATLLGFAVVYNSS
CQLTKYQSYMFK
>Mature_411_residues
PSSCINSLCHIIRAGFRMSQKKNITNPFYQGDLIFVYIVFFIISVVAVYAAQQFNQYNEPFAMKQSLYYLLGAFIIIVFL
YFDLEQLEKLSFYFYLLGILMLIVLKFSPAYIGSYRFAPVINGAKSWFMLPGFTLQPSEFMKIGLIMYLASFMSKNGPVG
KRTLKEDWIFLLKIAGIIIVPFGLILEQDTGTAGIVAFVILVMVFLSGVNWKLISLIFGTGLAAVALILYVIIKFPDVAG
ALGVEQYQINRVMTWVNPSEQNADDKMQVERAQMAIGSGKVFGNGVSDLQVYVPEAQTDFIFAVIGESFGFVGCTFVVIM
FFFLIYRLVVLIDRIHPFSRFASFFCAGFTALIVIHTFQNIGMNIGIMPVTGVPLLLVSYGGSSVVATLLGFAVVYNSSC
QLTKYQSYMFK

Specific function: This Is A Septum-Peptidoglycan Biosynthetic Protein, Involved In Cell Wall Formation. Plays A Role In The Stabilization Of The Ftsz Ring During Cell Division. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=410, Percent_Identity=28.2926829268293, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1786853, Length=333, Percent_Identity=31.2312312312312, Blast_Score=118, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 46069; Mature: 45938

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEHHHHHHCC
>Mature Secondary Structure 
PSSCINSLCHIIRAGFRMSQKKNITNPFYQGDLIFVYIVFFIISVVAVYAAQQFNQYNE
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PFAMKQSLYYLLGAFIIIVFLYFDLEQLEKLSFYFYLLGILMLIVLKFSPAYIGSYRFAP
CHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEECHH
VINGAKSWFMLPGFTLQPSEFMKIGLIMYLASFMSKNGPVGKRTLKEDWIFLLKIAGIII
HHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VPFGLILEQDTGTAGIVAFVILVMVFLSGVNWKLISLIFGTGLAAVALILYVIIKFPDVA
HHHHHEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCHH
GALGVEQYQINRVMTWVNPSEQNADDKMQVERAQMAIGSGKVFGNGVSDLQVYVPEAQTD
HHCCCHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCC
FIFAVIGESFGFVGCTFVVIMFFFLIYRLVVLIDRIHPFSRFASFFCAGFTALIVIHTFQ
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
NIGMNIGIMPVTGVPLLLVSYGGSSVVATLLGFAVVYNSSCQLTKYQSYMFK
HCCCCEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]