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The map label for this gene is argS

Identifier: 52787649

GI number: 52787649

Start: 3798493

End: 3800163

Strand: Reverse

Name: argS

Synonym: BLi03971

Alternate gene names: 52787649

Gene position: 3800163-3798493 (Counterclockwise)

Preceding gene: 52787650

Following gene: 52787647

Centisome position: 89.99

GC content: 48.77

Gene sequence:

>1671_bases
ATGAACATAGTCGAACAAATGAAAGATGTGCTGAAGCAGGAAATTAAGGAAGCTGTCATGAAAGCCGGCCTCGCCGAAGA
AAGCGAGATTCCAGAAGTCGTACTGGAAGTTCCGAAAGACAAGTCGCATGGCGACTATTCCACTAATATGGCTATGCAGC
TGGCGAGAATCGCCAAAAAAGCGCCGCGGAATATTGCCGAAGAAATCGTCGCATCCTTTGACAAAGGAAAAGCGTCGATC
GACAAACTTGATATCGCAGGACCTGGCTTTATCAATTTCTACATGAACAATCAATATTTAACGAAGCTGATTCCGGCTGT
GCTTGAAGCAGGAGAGGCCTACGGTGAAACAAATATCGGGGGCGGGGAACGCGTCCAGGTGGAATTCGTCTCAGCAAACC
CGACGGGCAACCTGCACCTTGGACATGCCCGCGGAGCCGCTGTCGGAGATTCCCTCTGCAATGTACTTGAAAAAGCGGGG
TATGAAGTGAGCCGCGAATATTATATCAACGATGCCGGCAATCAAATCAACAACCTCGCGTTATCCGTCGAAGCCCGTTA
CTTTCAGGCGCTTGGAAAAGATAAGCCGATGCCTGAAGACGGGTATCACGGCGAAGATATTAAGGAAATCGGCCAAAAGC
TCGCCGACGAATTCGGCGATCGTTTTGTTCATGAAGAAGAGAGCGAACGCCTCGCGTTTTTCCGCGAATACGGCTTAAAG
TACGAATTGGGCAAACTTCGTGAAGACCTGGAGAATTTCCGTGTCCCATTTGATGTCTGGTACTCTGAGACATCGCTTTA
CCAAAACGGAAAGATCGATCAGGCGCTCGAAGCCCTTCGCGAAAAAGGGCATATCTATGAAGAAGACGGAGCGACATGGT
TCCGCTCGACGGCGTTCGGCGATGACAAAGACCGCGTGCTGATCAAAAAAGACGGATCCTACACGTATCTTCTGCCTGAC
ATCGCTTATCACAAAGACAAGCTTGACCGCGGCTTCCAAAAGCTGATCAATGTATGGGGAGCAGACCATCACGGCTATAT
CCCGCGCATGAAAGCGGCTATTGAAGCGCTCGGTTATGACAAAGAAACGCTTGAGGTCGAGATCATTCAGCTCGTCCACC
TTTACAAAAACGGCGAAAAAATGAAAATGAGCAAAAGAACCGGAAAAGCCGTCACAATGCGCGATCTTATTGATGAGGTC
GGCCTTGACGCTGTGCGTTACTTCTTTGCGATGCGCAGCGCCGATACCCATATGGACTTTGACCTTGATCTGGCCGTCTC
AACATCTAATGAGAATCCAGTTTACTACGCGCAGTACGCCCATGCGAGAATTTGCAGCATGCTGCGCCAAGGCGAAGAAA
AAGGCATTTCTTTTGAAGGGAACCTTGATCTTACGAAGATCGGTTCTGAGAAAGAGTATGATCTGCTTAAAGTGATCGGC
TCGTTCCCTGAGGCCGTCGCTGATGCCGCAGAGAAGCGGATTCCGCACCGCATTACAAACTATATTTTTGAATTGGCATC
TGTGCTTCACAGCTTTTACAATGCTGAGAAAGTCCTCGATCCGGCAGATGAAGAAAAAAGCCGGGCCCGTTTATCATTGA
TGAAAGCAACGCAAATCACATTAAATAATGCCCTCAAGCTGATCGGCGTATCAGCGCCTGAAAAAATGTAA

Upstream 100 bases:

>100_bases
CGCCGGACGGAAAGATCAGCATTGAGTACGATATGATTGTAAGCGATGAACAAAAGCATTTACATAAGATGTCGATTTCG
TATAGAGGAGGACACGAGTC

Downstream 100 bases:

>100_bases
AACGAATCCCCCGTCCATTGAACGGGGGATTTTTTCTTGATTTGGTGAGGAGGCGTCTCGCAAAGGAAGAACTTCCGCCT
TCCCTTATTGAACTTGAGCG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MNIVEQMKDVLKQEIKEAVMKAGLAEESEIPEVVLEVPKDKSHGDYSTNMAMQLARIAKKAPRNIAEEIVASFDKGKASI
DKLDIAGPGFINFYMNNQYLTKLIPAVLEAGEAYGETNIGGGERVQVEFVSANPTGNLHLGHARGAAVGDSLCNVLEKAG
YEVSREYYINDAGNQINNLALSVEARYFQALGKDKPMPEDGYHGEDIKEIGQKLADEFGDRFVHEEESERLAFFREYGLK
YELGKLREDLENFRVPFDVWYSETSLYQNGKIDQALEALREKGHIYEEDGATWFRSTAFGDDKDRVLIKKDGSYTYLLPD
IAYHKDKLDRGFQKLINVWGADHHGYIPRMKAAIEALGYDKETLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIDEV
GLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEKGISFEGNLDLTKIGSEKEYDLLKVIG
SFPEAVADAAEKRIPHRITNYIFELASVLHSFYNAEKVLDPADEEKSRARLSLMKATQITLNNALKLIGVSAPEKM

Sequences:

>Translated_556_residues
MNIVEQMKDVLKQEIKEAVMKAGLAEESEIPEVVLEVPKDKSHGDYSTNMAMQLARIAKKAPRNIAEEIVASFDKGKASI
DKLDIAGPGFINFYMNNQYLTKLIPAVLEAGEAYGETNIGGGERVQVEFVSANPTGNLHLGHARGAAVGDSLCNVLEKAG
YEVSREYYINDAGNQINNLALSVEARYFQALGKDKPMPEDGYHGEDIKEIGQKLADEFGDRFVHEEESERLAFFREYGLK
YELGKLREDLENFRVPFDVWYSETSLYQNGKIDQALEALREKGHIYEEDGATWFRSTAFGDDKDRVLIKKDGSYTYLLPD
IAYHKDKLDRGFQKLINVWGADHHGYIPRMKAAIEALGYDKETLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIDEV
GLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEKGISFEGNLDLTKIGSEKEYDLLKVIG
SFPEAVADAAEKRIPHRITNYIFELASVLHSFYNAEKVLDPADEEKSRARLSLMKATQITLNNALKLIGVSAPEKM
>Mature_556_residues
MNIVEQMKDVLKQEIKEAVMKAGLAEESEIPEVVLEVPKDKSHGDYSTNMAMQLARIAKKAPRNIAEEIVASFDKGKASI
DKLDIAGPGFINFYMNNQYLTKLIPAVLEAGEAYGETNIGGGERVQVEFVSANPTGNLHLGHARGAAVGDSLCNVLEKAG
YEVSREYYINDAGNQINNLALSVEARYFQALGKDKPMPEDGYHGEDIKEIGQKLADEFGDRFVHEEESERLAFFREYGLK
YELGKLREDLENFRVPFDVWYSETSLYQNGKIDQALEALREKGHIYEEDGATWFRSTAFGDDKDRVLIKKDGSYTYLLPD
IAYHKDKLDRGFQKLINVWGADHHGYIPRMKAAIEALGYDKETLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIDEV
GLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEKGISFEGNLDLTKIGSEKEYDLLKVIG
SFPEAVADAAEKRIPHRITNYIFELASVLHSFYNAEKVLDPADEEKSRARLSLMKATQITLNNALKLIGVSAPEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=620, Percent_Identity=23.5483870967742, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI197100773, Length=617, Percent_Identity=22.2042139384117, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1788184, Length=603, Percent_Identity=26.2023217247098, Blast_Score=145, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI71985061, Length=624, Percent_Identity=25.6410256410256, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71985068, Length=585, Percent_Identity=25.6410256410256, Blast_Score=121, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320548, Length=607, Percent_Identity=24.8764415156507, Blast_Score=148, Evalue=3e-36,
Organism=Drosophila melanogaster, GI18859963, Length=624, Percent_Identity=24.8397435897436, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28571570, Length=507, Percent_Identity=24.65483234714, Blast_Score=92, Evalue=1e-18,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_BACLD (Q65DS9)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_081049.1
- RefSeq:   YP_093478.1
- ProteinModelPortal:   Q65DS9
- STRING:   Q65DS9
- EnsemblBacteria:   EBBACT00000057228
- EnsemblBacteria:   EBBACT00000059045
- GeneID:   3027964
- GeneID:   3101407
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi03971
- KEGG:   bli:BL03923
- NMPDR:   fig|279010.5.peg.4156
- eggNOG:   COG0018
- GeneTree:   EBGT00050000002259
- HOGENOM:   HBG695395
- OMA:   FFAMRSS
- ProtClustDB:   PRK01611
- BioCyc:   BLIC279010-1:BLI03971-MONOMER
- BioCyc:   BLIC279010:BL03923-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 62657; Mature: 62657

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVEQMKDVLKQEIKEAVMKAGLAEESEIPEVVLEVPKDKSHGDYSTNMAMQLARIAKK
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
APRNIAEEIVASFDKGKASIDKLDIAGPGFINFYMNNQYLTKLIPAVLEAGEAYGETNIG
CCHHHHHHHHHHHCCCCCCCCCEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCC
GGERVQVEFVSANPTGNLHLGHARGAAVGDSLCNVLEKAGYEVSREYYINDAGNQINNLA
CCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHEE
LSVEARYFQALGKDKPMPEDGYHGEDIKEIGQKLADEFGDRFVHEEESERLAFFREYGLK
EEHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
YELGKLREDLENFRVPFDVWYSETSLYQNGKIDQALEALREKGHIYEEDGATWFRSTAFG
CHHHHHHHHHHHCCCCCEEEECHHHHHCCCCHHHHHHHHHHCCCEEECCCCCEEECCCCC
DDKDRVLIKKDGSYTYLLPDIAYHKDKLDRGFQKLINVWGADHHGYIPRMKAAIEALGYD
CCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
KETLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIDEVGLDAVRYFFAMRSADTHMDF
CHHHHHHHHHHHHHHHCCCCEEHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHCCCCCCCE
DLDLAVSTSNENPVYYAQYAHARICSMLRQGEEKGISFEGNLDLTKIGSEKEYDLLKVIG
EEEEEEECCCCCCEEEEHHHHHHHHHHHHCCHHCCCCEECCCCCEECCCCCHHHHHHHHH
SFPEAVADAAEKRIPHRITNYIFELASVLHSFYNAEKVLDPADEEKSRARLSLMKATQIT
HCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LNNALKLIGVSAPEKM
HHHCHHEEECCCCCCC
>Mature Secondary Structure
MNIVEQMKDVLKQEIKEAVMKAGLAEESEIPEVVLEVPKDKSHGDYSTNMAMQLARIAKK
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
APRNIAEEIVASFDKGKASIDKLDIAGPGFINFYMNNQYLTKLIPAVLEAGEAYGETNIG
CCHHHHHHHHHHHCCCCCCCCCEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCC
GGERVQVEFVSANPTGNLHLGHARGAAVGDSLCNVLEKAGYEVSREYYINDAGNQINNLA
CCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHEE
LSVEARYFQALGKDKPMPEDGYHGEDIKEIGQKLADEFGDRFVHEEESERLAFFREYGLK
EEHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
YELGKLREDLENFRVPFDVWYSETSLYQNGKIDQALEALREKGHIYEEDGATWFRSTAFG
CHHHHHHHHHHHCCCCCEEEECHHHHHCCCCHHHHHHHHHHCCCEEECCCCCEEECCCCC
DDKDRVLIKKDGSYTYLLPDIAYHKDKLDRGFQKLINVWGADHHGYIPRMKAAIEALGYD
CCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
KETLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIDEVGLDAVRYFFAMRSADTHMDF
CHHHHHHHHHHHHHHHCCCCEEHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHCCCCCCCE
DLDLAVSTSNENPVYYAQYAHARICSMLRQGEEKGISFEGNLDLTKIGSEKEYDLLKVIG
EEEEEEECCCCCCEEEEHHHHHHHHHHHHCCHHCCCCEECCCCCEECCCCCHHHHHHHHH
SFPEAVADAAEKRIPHRITNYIFELASVLHSFYNAEKVLDPADEEKSRARLSLMKATQIT
HCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LNNALKLIGVSAPEKM
HHHCHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA