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The map label for this gene is yhjM [H]

Identifier: 52787625

GI number: 52787625

Start: 3771308

End: 3772297

Strand: Direct

Name: yhjM [H]

Synonym: BLi03947

Alternate gene names: 52787625

Gene position: 3771308-3772297 (Clockwise)

Preceding gene: 52787596

Following gene: 52787628

Centisome position: 89.31

GC content: 44.65

Gene sequence:

>990_bases
ATGCCTACGATTGACGAAATTGCAAAATTAAGTAATGTGTCAAAAACAACTGTTTCAAGAGTACTGAACGATCATCCCTA
TGTATCTGAAGAAAAAAGGAAGCGGGTTTTGGAAGTCATCGAAAAATTGGACTACATCCCGAACACGTCTGCACGAAAGC
TCAGATCCAACAAAACGATGTTTCTCGCAGTGTCTGTCCCACACGCGGACCACCCCTTCTTCGCTCAGCTTATGAAGCAT
ATGTCCGCTGAAGCGCTGAAACACCAATACAAAGTCATTGTGTTTCAGACGTTTTATCAAAAGCAGAATGAACTGAAAGT
ACTGGAGCTGCTCAAGAGGAAAGAAGTCGACGGCGTTATGCTATGCAGCCTTGAAAATGAATGGGAAGACATCAAAAAAT
ACGTCAAATACGGTCCCGTGGTTATGGCAAATGAATTCCACGCCGAAGCGGACGTGCCGGTGATCTGCTATGACGAATTC
GAAGCCGGATATAAAGGAACGGAGCTTTTTATTCAAAAAGGGCATCATTTAATGGCCTTTTGCTGTGACACGATACACAG
CAAGGCCCAGATTATGAGAAAAGAAGGGTTTATGAAAGCATTGTCTGATGCAGGTTTGCGTTTCCAGGAGAAGTGGATGT
TCAGCCACGCATTTACCATTCATGACGGCTTCCGCATTATGGACCAGATCCACAACATGTCCGAAAAGCCGACCGCCATT
TTTACGGGAAACGACCAAGTGGCCGCAGGAATTATTAAAAGGGCCCGATATTATCAATATGAAGTGCCAAAGCAGCTTGC
AGTGCTTGGATATGACAATCAATCGATCTGTGAGGTGACCGATCCGGAAATCACGACAATCGATATACCTGTTGAAGAGC
TGGCTCAAAAAGCCGTATGTGCAATGGTAAACCTTCTGAATGGGGAAAGCGGCTTACAGAGGGATGTCGTGACACTGTCC
CCTGCATTAAAAATAAGACAATCTGTTTAG

Upstream 100 bases:

>100_bases
CACCCCATTTTTATTATTTTGGGAAATTGTCATATTTCATGACATATCTTAAATGATGGAATCGATACCATAACAACTCT
TTTTTTCAGGAAGTGACTTT

Downstream 100 bases:

>100_bases
TATATATATTAATCTTGAACTATTTTTTATTTTATTCAGATAAAAATTTTGTTAAAAAATGGTAAAGCACGCCGCCAGAA
CGGTCAAGGCTGCGGTTCCT

Product: YhjM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MPTIDEIAKLSNVSKTTVSRVLNDHPYVSEEKRKRVLEVIEKLDYIPNTSARKLRSNKTMFLAVSVPHADHPFFAQLMKH
MSAEALKHQYKVIVFQTFYQKQNELKVLELLKRKEVDGVMLCSLENEWEDIKKYVKYGPVVMANEFHAEADVPVICYDEF
EAGYKGTELFIQKGHHLMAFCCDTIHSKAQIMRKEGFMKALSDAGLRFQEKWMFSHAFTIHDGFRIMDQIHNMSEKPTAI
FTGNDQVAAGIIKRARYYQYEVPKQLAVLGYDNQSICEVTDPEITTIDIPVEELAQKAVCAMVNLLNGESGLQRDVVTLS
PALKIRQSV

Sequences:

>Translated_329_residues
MPTIDEIAKLSNVSKTTVSRVLNDHPYVSEEKRKRVLEVIEKLDYIPNTSARKLRSNKTMFLAVSVPHADHPFFAQLMKH
MSAEALKHQYKVIVFQTFYQKQNELKVLELLKRKEVDGVMLCSLENEWEDIKKYVKYGPVVMANEFHAEADVPVICYDEF
EAGYKGTELFIQKGHHLMAFCCDTIHSKAQIMRKEGFMKALSDAGLRFQEKWMFSHAFTIHDGFRIMDQIHNMSEKPTAI
FTGNDQVAAGIIKRARYYQYEVPKQLAVLGYDNQSICEVTDPEITTIDIPVEELAQKAVCAMVNLLNGESGLQRDVVTLS
PALKIRQSV
>Mature_328_residues
PTIDEIAKLSNVSKTTVSRVLNDHPYVSEEKRKRVLEVIEKLDYIPNTSARKLRSNKTMFLAVSVPHADHPFFAQLMKHM
SAEALKHQYKVIVFQTFYQKQNELKVLELLKRKEVDGVMLCSLENEWEDIKKYVKYGPVVMANEFHAEADVPVICYDEFE
AGYKGTELFIQKGHHLMAFCCDTIHSKAQIMRKEGFMKALSDAGLRFQEKWMFSHAFTIHDGFRIMDQIHNMSEKPTAIF
TGNDQVAAGIIKRARYYQYEVPKQLAVLGYDNQSICEVTDPEITTIDIPVEELAQKAVCAMVNLLNGESGLQRDVVTLSP
ALKIRQSV

Specific function: Positively regulates the ntdABC operon and negatively regulates its own transcription. Binds to NTD to induce ntdABC transcription [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=330, Percent_Identity=28.7878787878788, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1790369, Length=308, Percent_Identity=26.9480519480519, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1787948, Length=302, Percent_Identity=29.8013245033113, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1788474, Length=299, Percent_Identity=26.4214046822742, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1787580, Length=333, Percent_Identity=28.8288288288288, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789068, Length=314, Percent_Identity=27.3885350318471, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1789202, Length=298, Percent_Identity=24.8322147651007, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI48994940, Length=328, Percent_Identity=23.4756097560976, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790689, Length=330, Percent_Identity=25.4545454545455, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787906, Length=299, Percent_Identity=26.4214046822742, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790715, Length=304, Percent_Identity=21.0526315789474, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786268, Length=300, Percent_Identity=20, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37654; Mature: 37523

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTIDEIAKLSNVSKTTVSRVLNDHPYVSEEKRKRVLEVIEKLDYIPNTSARKLRSNKTM
CCCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEE
FLAVSVPHADHPFFAQLMKHMSAEALKHQYKVIVFQTFYQKQNELKVLELLKRKEVDGVM
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHEEEHHHHCCCCCHHHHHHHHHCCCCCEE
LCSLENEWEDIKKYVKYGPVVMANEFHAEADVPVICYDEFEAGYKGTELFIQKGHHLMAF
EEECCCHHHHHHHHHHHCCEEEECCCCCCCCCCEEEECCCCCCCCCHHHHHHCCCHHHHH
CCDTIHSKAQIMRKEGFMKALSDAGLRFQEKWMFSHAFTIHDGFRIMDQIHNMSEKPTAI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEHHHHHHHHHHHCCCCCCCEE
FTGNDQVAAGIIKRARYYQYEVPKQLAVLGYDNQSICEVTDPEITTIDIPVEELAQKAVC
EECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCEEEEECCHHHHHHHHHH
AMVNLLNGESGLQRDVVTLSPALKIRQSV
HHHHHHCCCCCCCCCHHHHCHHHHHHCCC
>Mature Secondary Structure 
PTIDEIAKLSNVSKTTVSRVLNDHPYVSEEKRKRVLEVIEKLDYIPNTSARKLRSNKTM
CCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEE
FLAVSVPHADHPFFAQLMKHMSAEALKHQYKVIVFQTFYQKQNELKVLELLKRKEVDGVM
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHEEEHHHHCCCCCHHHHHHHHHCCCCCEE
LCSLENEWEDIKKYVKYGPVVMANEFHAEADVPVICYDEFEAGYKGTELFIQKGHHLMAF
EEECCCHHHHHHHHHHHCCEEEECCCCCCCCCCEEEECCCCCCCCCHHHHHHCCCHHHHH
CCDTIHSKAQIMRKEGFMKALSDAGLRFQEKWMFSHAFTIHDGFRIMDQIHNMSEKPTAI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEHHHHHHHHHHHCCCCCCCEE
FTGNDQVAAGIIKRARYYQYEVPKQLAVLGYDNQSICEVTDPEITTIDIPVEELAQKAVC
EECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCEEEEECCHHHHHHHHHH
AMVNLLNGESGLQRDVVTLSPALKIRQSV
HHHHHHCCCCCCCCCHHHHCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]