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The map label for this gene is ywlC [H]

Identifier: 52787618

GI number: 52787618

Start: 3763959

End: 3765008

Strand: Reverse

Name: ywlC [H]

Synonym: BLi03940

Alternate gene names: 52787618

Gene position: 3765008-3763959 (Counterclockwise)

Preceding gene: 52787619

Following gene: 52787617

Centisome position: 89.16

GC content: 53.9

Gene sequence:

>1050_bases
ATGTTAATGAAAACAAAAGTATGGACTGTGGATGTAAAACGCGATTTGTCCACAAACTGTCCACAAATTGCACAGGCGGC
AAGACTGCTTCAGCAAAATGAAACGGTTGCTTTTCCGACAGAGACTGTTTACGGTCTTGGTGCAAACGCCAAACACAGCG
AAGCAGTAGCTAAAATATACGAAGCGAAAGGGCGGCCGAGCGACAATCCGCTCATTGTCCACATCGCTGAAATTGAACAG
CTTGCAGAATTTGCGGAAGTTGATTCGCCTCAGGCCGAAATGCTGATGAAGCGTTTTTGGCCCGGGCCGCTGACCCTTGT
GCTGCCGTGCAAGCCCGGGGTGTTATCCACAAGGGTGACGGCGGGGCTCGACACGGTCGCGGTTAGAATGCCTGATCATC
CTGTGGCGCTTGAGCTGATTAGACAGGCCGGCGTTCCGGTGGCTGCCCCGAGCGCAAATCTGTCCGGAAAACCGAGTCCG
ACGAAAGCCGAGCATGTCGTCAACGATTTGAATGGACGGATTGCGGGTGTCGTTGACGGCGGCCCTACAGGAGTAGGGGT
TGAATCAACAGTTGTTTCATGCACCGGTGAAATTCCGGTCATTTTGAGGCCGGGCGGCGTCACAAAAGAGCAGCTCGAAG
AAGCGGCCGGCCCCGTCTTGATTGACCAGGGCCTCACCGACGAAAAAAAGGCGCCTATGTCTCCCGGGATGAAATATACG
CATTATGCACCGGAAGCACCTCTTGCTATTGTGAACGGGGGAGTTGAGGATATTCAACGGCTGATCGACCAATATCAGAA
AGACGGGATGAAAGTCGGTGTCCTTACGACAGAGGAACGGGCCGATGTCTATCAGGCCGATGCCGTCCGCATCTGCGGCA
GAAGAGACCGACTTGAAACGGTTGCCGCCGGTTTGTATGACGTTCTCCGCAGCTTTGATGAAGAACGTCTCGATTTTATT
TTTGCGGAGTCTTTTCCTGAGGAAGGAGTGGGCCGGGCGATTATGAACCGGCTGTTGAAAGCGGCCGGCCACCGCGTAAT
CGAAGCGTAG

Upstream 100 bases:

>100_bases
AATGTGGACAACGCTTGTTTTCTTTTCTTTCATCTTTTATACTTTCAACATGATTTACATGAATTATTAACGTTTTTAGT
GTTTTGTTAAGGGAGTTTTG

Downstream 100 bases:

>100_bases
CCTAAGCGGGGGTGTTCTATCTGCCTTTGGACGTGCATAAGCTAGAAAAGCTGGCGTGTCCAAGGGGGAATTGCATGAAT
GTTGATGTGTTAATAGGCGA

Product: YwlC

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MLMKTKVWTVDVKRDLSTNCPQIAQAARLLQQNETVAFPTETVYGLGANAKHSEAVAKIYEAKGRPSDNPLIVHIAEIEQ
LAEFAEVDSPQAEMLMKRFWPGPLTLVLPCKPGVLSTRVTAGLDTVAVRMPDHPVALELIRQAGVPVAAPSANLSGKPSP
TKAEHVVNDLNGRIAGVVDGGPTGVGVESTVVSCTGEIPVILRPGGVTKEQLEEAAGPVLIDQGLTDEKKAPMSPGMKYT
HYAPEAPLAIVNGGVEDIQRLIDQYQKDGMKVGVLTTEERADVYQADAVRICGRRDRLETVAAGLYDVLRSFDEERLDFI
FAESFPEEGVGRAIMNRLLKAAGHRVIEA

Sequences:

>Translated_349_residues
MLMKTKVWTVDVKRDLSTNCPQIAQAARLLQQNETVAFPTETVYGLGANAKHSEAVAKIYEAKGRPSDNPLIVHIAEIEQ
LAEFAEVDSPQAEMLMKRFWPGPLTLVLPCKPGVLSTRVTAGLDTVAVRMPDHPVALELIRQAGVPVAAPSANLSGKPSP
TKAEHVVNDLNGRIAGVVDGGPTGVGVESTVVSCTGEIPVILRPGGVTKEQLEEAAGPVLIDQGLTDEKKAPMSPGMKYT
HYAPEAPLAIVNGGVEDIQRLIDQYQKDGMKVGVLTTEERADVYQADAVRICGRRDRLETVAAGLYDVLRSFDEERLDFI
FAESFPEEGVGRAIMNRLLKAAGHRVIEA
>Mature_349_residues
MLMKTKVWTVDVKRDLSTNCPQIAQAARLLQQNETVAFPTETVYGLGANAKHSEAVAKIYEAKGRPSDNPLIVHIAEIEQ
LAEFAEVDSPQAEMLMKRFWPGPLTLVLPCKPGVLSTRVTAGLDTVAVRMPDHPVALELIRQAGVPVAAPSANLSGKPSP
TKAEHVVNDLNGRIAGVVDGGPTGVGVESTVVSCTGEIPVILRPGGVTKEQLEEAAGPVLIDQGLTDEKKAPMSPGMKYT
HYAPEAPLAIVNGGVEDIQRLIDQYQKDGMKVGVLTTEERADVYQADAVRICGRRDRLETVAAGLYDVLRSFDEERLDFI
FAESFPEEGVGRAIMNRLLKAAGHRVIEA

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=184, Percent_Identity=34.7826086956522, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI2367210, Length=139, Percent_Identity=38.1294964028777, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081864, Length=184, Percent_Identity=25, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17537239, Length=208, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321269, Length=375, Percent_Identity=39.2, Blast_Score=213, Evalue=3e-56,
Organism=Drosophila melanogaster, GI78707274, Length=170, Percent_Identity=30.5882352941176, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 37604; Mature: 37604

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMKTKVWTVDVKRDLSTNCPQIAQAARLLQQNETVAFPTETVYGLGANAKHSEAVAKIY
CCEEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEECCCHHHEECCCCCCHHHHHHHHH
EAKGRPSDNPLIVHIAEIEQLAEFAEVDSPQAEMLMKRFWPGPLTLVLPCKPGVLSTRVT
HHCCCCCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHH
AGLDTVAVRMPDHPVALELIRQAGVPVAAPSANLSGKPSPTKAEHVVNDLNGRIAGVVDG
CCCCEEEEECCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHCCCEEEEEECC
GPTGVGVESTVVSCTGEIPVILRPGGVTKEQLEEAAGPVLIDQGLTDEKKAPMSPGMKYT
CCCCCCCCCEEEEECCCCCEEECCCCCCHHHHHHHCCCEEEECCCCCCCCCCCCCCCCEE
HYAPEAPLAIVNGGVEDIQRLIDQYQKDGMKVGVLTTEERADVYQADAVRICGRRDRLET
ECCCCCCEEEECCCHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHCCCHHHHHH
VAAGLYDVLRSFDEERLDFIFAESFPEEGVGRAIMNRLLKAAGHRVIEA
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MLMKTKVWTVDVKRDLSTNCPQIAQAARLLQQNETVAFPTETVYGLGANAKHSEAVAKIY
CCEEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEECCCHHHEECCCCCCHHHHHHHHH
EAKGRPSDNPLIVHIAEIEQLAEFAEVDSPQAEMLMKRFWPGPLTLVLPCKPGVLSTRVT
HHCCCCCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHH
AGLDTVAVRMPDHPVALELIRQAGVPVAAPSANLSGKPSPTKAEHVVNDLNGRIAGVVDG
CCCCEEEEECCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHCCCEEEEEECC
GPTGVGVESTVVSCTGEIPVILRPGGVTKEQLEEAAGPVLIDQGLTDEKKAPMSPGMKYT
CCCCCCCCCEEEEECCCCCEEECCCCCCHHHHHHHCCCEEEECCCCCCCCCCCCCCCCEE
HYAPEAPLAIVNGGVEDIQRLIDQYQKDGMKVGVLTTEERADVYQADAVRICGRRDRLET
ECCCCCCEEEECCCHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHCCCHHHHHH
VAAGLYDVLRSFDEERLDFIFAESFPEEGVGRAIMNRLLKAAGHRVIEA
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]