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The map label for this gene is yvaK [H]

Identifier: 52787327

GI number: 52787327

Start: 3472540

End: 3473286

Strand: Reverse

Name: yvaK [H]

Synonym: BLi03642

Alternate gene names: 52787327

Gene position: 3473286-3472540 (Counterclockwise)

Preceding gene: 52787328

Following gene: 52787326

Centisome position: 82.25

GC content: 44.98

Gene sequence:

>747_bases
ATGAAAATTGTCAAACCACAACCTTTCACATTTAAAGGCGGAAAAAAAGCCGTCCTGCTGCTGCACGGATTTACGGGCAA
CACGGCGGACGTTAGAATGCTCGGAAGATATTTGAATGAAAAAGGCTACACATGCCATGCGCCCCAATATAAAGGCCACG
GCGTGCCTCCAGAAGAACTTCTCTCCACAGGACCGGAAGACTGGTGGAAAGACGTCATGGACGGATATGAATATCTGAAA
TCGGAAGGATATGAACAAATCGCCGCTTGCGGACTGTCTCTCGGAGGGGTTTTTTCATTGAAATTGGGTTACACTGTACC
CATAAAGGGAATTGTTCCAATGTGCGCGCCGATGTACATCAAAAGCGAAGAGACGATGTACGAGGGTGTGCTTGATTATG
CCCGCAATTATAAGAAATTTGAAGGCAAGACAGCGGAGCAGATTAACGCTGAGATGGAAGAATTCAAAAAAACGCCGATG
AACACGTTGAAAGCACTGCAGGATTTGATTGCCGATGTCAGAGAGCATGTGGACATGATCTATTCGCCTACATTTGTCGT
GCAGGCGCGCCACGATCATATGATTAATACGGATAGCGCAAACATCATCTACAATGAAGTTGAAACGGATGATAAGCAGC
TGAAATGGTATGAAGAATCAGGTCATGCCATCACATTGGATAAAGAACGCGAAACACTGCACAAGGATGTGTATCAATTT
TTAGAAACGTTGGATTGGCAGACATAA

Upstream 100 bases:

>100_bases
TTCCTATTTGCCGGTCTTTGTCTGAAGGGGCCGGCCGATTGATAAAGTTTGTTTCAAGACTAAACGTGGAAGAATACATA
TGAAAAGGAGACAGTGAATC

Downstream 100 bases:

>100_bases
GGAGGTCTGATTAGTGGAAAAAGAAGAATTTATGGATAAGCTTCTCTCCTTTATGAAAGAAGAAGCATATAAACCTCTTA
CAGTTCAGGAACTGGAAGAG

Product: YvaK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKIVKPQPFTFKGGKKAVLLLHGFTGNTADVRMLGRYLNEKGYTCHAPQYKGHGVPPEELLSTGPEDWWKDVMDGYEYLK
SEGYEQIAACGLSLGGVFSLKLGYTVPIKGIVPMCAPMYIKSEETMYEGVLDYARNYKKFEGKTAEQINAEMEEFKKTPM
NTLKALQDLIADVREHVDMIYSPTFVVQARHDHMINTDSANIIYNEVETDDKQLKWYEESGHAITLDKERETLHKDVYQF
LETLDWQT

Sequences:

>Translated_248_residues
MKIVKPQPFTFKGGKKAVLLLHGFTGNTADVRMLGRYLNEKGYTCHAPQYKGHGVPPEELLSTGPEDWWKDVMDGYEYLK
SEGYEQIAACGLSLGGVFSLKLGYTVPIKGIVPMCAPMYIKSEETMYEGVLDYARNYKKFEGKTAEQINAEMEEFKKTPM
NTLKALQDLIADVREHVDMIYSPTFVVQARHDHMINTDSANIIYNEVETDDKQLKWYEESGHAITLDKERETLHKDVYQF
LETLDWQT
>Mature_248_residues
MKIVKPQPFTFKGGKKAVLLLHGFTGNTADVRMLGRYLNEKGYTCHAPQYKGHGVPPEELLSTGPEDWWKDVMDGYEYLK
SEGYEQIAACGLSLGGVFSLKLGYTVPIKGIVPMCAPMYIKSEETMYEGVLDYARNYKKFEGKTAEQINAEMEEFKKTPM
NTLKALQDLIADVREHVDMIYSPTFVVQARHDHMINTDSANIIYNEVETDDKQLKWYEESGHAITLDKERETLHKDVYQF
LETLDWQT

Specific function: Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones [H]

COG id: COG1647

COG function: function code R; Esterase/lipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019149
- InterPro:   IPR012354 [H]

Pfam domain/function: PF09752 DUF2048 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 28410; Mature: 28410

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVKPQPFTFKGGKKAVLLLHGFTGNTADVRMLGRYLNEKGYTCHAPQYKGHGVPPEEL
CCCCCCCCCEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHH
LSTGPEDWWKDVMDGYEYLKSEGYEQIAACGLSLGGVFSLKLGYTVPIKGIVPMCAPMYI
HHCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHCCEEE
KSEETMYEGVLDYARNYKKFEGKTAEQINAEMEEFKKTPMNTLKALQDLIADVREHVDMI
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
YSPTFVVQARHDHMINTDSANIIYNEVETDDKQLKWYEESGHAITLDKERETLHKDVYQF
HCCEEEEEECCCCEECCCCCCEEEECCCCCHHHHEEEECCCCEEEECHHHHHHHHHHHHH
LETLDWQT
HHHHCCCC
>Mature Secondary Structure
MKIVKPQPFTFKGGKKAVLLLHGFTGNTADVRMLGRYLNEKGYTCHAPQYKGHGVPPEEL
CCCCCCCCCEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHH
LSTGPEDWWKDVMDGYEYLKSEGYEQIAACGLSLGGVFSLKLGYTVPIKGIVPMCAPMYI
HHCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHCCEEE
KSEETMYEGVLDYARNYKKFEGKTAEQINAEMEEFKKTPMNTLKALQDLIADVREHVDMI
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
YSPTFVVQARHDHMINTDSANIIYNEVETDDKQLKWYEESGHAITLDKERETLHKDVYQF
HCCEEEEEECCCCEECCCCCCEEEECCCCCHHHHEEEECCCCEEEECHHHHHHHHHHHHH
LETLDWQT
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]