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The map label for this gene is yvqE [H]

Identifier: 52787184

GI number: 52787184

Start: 3333302

End: 3334366

Strand: Reverse

Name: yvqE [H]

Synonym: BLi03493

Alternate gene names: 52787184

Gene position: 3334366-3333302 (Counterclockwise)

Preceding gene: 52787185

Following gene: 52787183

Centisome position: 78.96

GC content: 48.92

Gene sequence:

>1065_bases
ATGAGAACGAACAGACTTGCAAACATTCAATGGCGCGCCGTCCGCTTATCCCTTGGTGTCAGCTTTACGATTTTTCTTGC
TGTATTGGGCTTTATGCTGTTTTATTACCAGCTGGATCCGAGGGTGCTCATCGTTTCCAGGTGGTTCGGGATTCCGTTTA
TCGCGCTTCTCGCATTGATCAGCACAGCTGTCGGGTTCGGCTCAGGCTATATGTTCGGCAATCAGCTGAAAAAACGGCTT
GAAAAGCTGATCGAGTCTATTCTAAAGTACGAAAACGGCAACTTTGCCTACCGGATTCCATCGCTTGGAGACGATGAGAT
CGGGCTGGCCGCCGACCAGCTCAATGAGATGGCCGAACGGATCGAAAGACAGGTTGCCTCTTTGCAAAAGCTGTCCAATG
AGAGAGCGGAATGGCAGGATCAAATGAAAAAATCGGTGATCTCCGAAGAGCGGCAGCGTCTCGCGCGCGAATTGCATGAT
GCGGTGAGCCAGCAGCTGTTTGCGATTTCCATGATGACTTCAGCTGTTTTGGAGGGAATCGATGCTGCGGCTGATGAAAA
GCTCGCTCAAAGGCTGAAAATGGTCGAAAAAATGGCGGCCGATGCCCAGAATGAAATGAGGGCGCTCCTTTTGCATTTGC
GACCTGTTACGCTTGAAGGGAAAGGTCTACAAGAAGGGCTTGCAGACCTTTTGAAAGAATTTAAAGCGAAACAGTCGATC
GACATCGATTGGGAGATTGAGGATGCGGGCAAACTTCCGAAAGGTGTGGAAGACCACCTGTTCAGGATCGTTCAAGAAGC
GCTCTCAAACGTGTTCCGGCATTCAAAAGCGACAAAAGTCACCGTCAGACTGCTGCTCAGGAACAAACAGCTCCAGTTGA
AAGTCATTGACAATGGCGAAGGATTTAAGATGGATGCCGTCAAAACATCTTCGTACGGGCTGAACTCGATCAAGGAAAGA
GCCAGCGAAGTCGGCGGAGTGGCAGAAATCATTTCATTTACGGGAAAAGGAACACAGGTTGATGTAAAGGTTCCGATTTT
TGAACAACAAAAAGGAGAGGCTTAA

Upstream 100 bases:

>100_bases
GCAATCAAATCTATTCCGAGACAGAGAATTACGAGCAGTCGGCACGACGGGTCAAAATTTCGATTTCGCTGTTTATCGGC
GATGTGGATGTGCGGTTCAT

Downstream 100 bases:

>100_bases
AAGGTGATTCGAGTATTGTTAATTGATGATCATGAAATGGTGAGAATGGGGCTGGCCGCTTTCCTGGAATCCCAGCCTGA
TATTGAAGTGATTGGGGAGG

Product: YvqE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MRTNRLANIQWRAVRLSLGVSFTIFLAVLGFMLFYYQLDPRVLIVSRWFGIPFIALLALISTAVGFGSGYMFGNQLKKRL
EKLIESILKYENGNFAYRIPSLGDDEIGLAADQLNEMAERIERQVASLQKLSNERAEWQDQMKKSVISEERQRLARELHD
AVSQQLFAISMMTSAVLEGIDAAADEKLAQRLKMVEKMAADAQNEMRALLLHLRPVTLEGKGLQEGLADLLKEFKAKQSI
DIDWEIEDAGKLPKGVEDHLFRIVQEALSNVFRHSKATKVTVRLLLRNKQLQLKVIDNGEGFKMDAVKTSSYGLNSIKER
ASEVGGVAEIISFTGKGTQVDVKVPIFEQQKGEA

Sequences:

>Translated_354_residues
MRTNRLANIQWRAVRLSLGVSFTIFLAVLGFMLFYYQLDPRVLIVSRWFGIPFIALLALISTAVGFGSGYMFGNQLKKRL
EKLIESILKYENGNFAYRIPSLGDDEIGLAADQLNEMAERIERQVASLQKLSNERAEWQDQMKKSVISEERQRLARELHD
AVSQQLFAISMMTSAVLEGIDAAADEKLAQRLKMVEKMAADAQNEMRALLLHLRPVTLEGKGLQEGLADLLKEFKAKQSI
DIDWEIEDAGKLPKGVEDHLFRIVQEALSNVFRHSKATKVTVRLLLRNKQLQLKVIDNGEGFKMDAVKTSSYGLNSIKER
ASEVGGVAEIISFTGKGTQVDVKVPIFEQQKGEA
>Mature_354_residues
MRTNRLANIQWRAVRLSLGVSFTIFLAVLGFMLFYYQLDPRVLIVSRWFGIPFIALLALISTAVGFGSGYMFGNQLKKRL
EKLIESILKYENGNFAYRIPSLGDDEIGLAADQLNEMAERIERQVASLQKLSNERAEWQDQMKKSVISEERQRLARELHD
AVSQQLFAISMMTSAVLEGIDAAADEKLAQRLKMVEKMAADAQNEMRALLLHLRPVTLEGKGLQEGLADLLKEFKAKQSI
DIDWEIEDAGKLPKGVEDHLFRIVQEALSNVFRHSKATKVTVRLLLRNKQLQLKVIDNGEGFKMDAVKTSSYGLNSIKER
ASEVGGVAEIISFTGKGTQVDVKVPIFEQQKGEA

Specific function: Member of the two-component regulatory system liaS/liaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin, nisin, ramoplanin and vancomycin). Seems also

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=217, Percent_Identity=29.0322580645161, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI87082311, Length=242, Percent_Identity=26.8595041322314, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788812, Length=222, Percent_Identity=27.027027027027, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017202 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39804; Mature: 39804

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTNRLANIQWRAVRLSLGVSFTIFLAVLGFMLFYYQLDPRVLIVSRWFGIPFIALLALI
CCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCHHHHHHHHHH
STAVGFGSGYMFGNQLKKRLEKLIESILKYENGNFAYRIPSLGDDEIGLAADQLNEMAER
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHH
IERQVASLQKLSNERAEWQDQMKKSVISEERQRLARELHDAVSQQLFAISMMTSAVLEGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAAADEKLAQRLKMVEKMAADAQNEMRALLLHLRPVTLEGKGLQEGLADLLKEFKAKQSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHCCC
DIDWEIEDAGKLPKGVEDHLFRIVQEALSNVFRHSKATKVTVRLLLRNKQLQLKVIDNGE
CCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCC
GFKMDAVKTSSYGLNSIKERASEVGGVAEIISFTGKGTQVDVKVPIFEQQKGEA
CEEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MRTNRLANIQWRAVRLSLGVSFTIFLAVLGFMLFYYQLDPRVLIVSRWFGIPFIALLALI
CCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCHHHHHHHHHH
STAVGFGSGYMFGNQLKKRLEKLIESILKYENGNFAYRIPSLGDDEIGLAADQLNEMAER
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHH
IERQVASLQKLSNERAEWQDQMKKSVISEERQRLARELHDAVSQQLFAISMMTSAVLEGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAAADEKLAQRLKMVEKMAADAQNEMRALLLHLRPVTLEGKGLQEGLADLLKEFKAKQSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHCCC
DIDWEIEDAGKLPKGVEDHLFRIVQEALSNVFRHSKATKVTVRLLLRNKQLQLKVIDNGE
CCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCC
GFKMDAVKTSSYGLNSIKERASEVGGVAEIISFTGKGTQVDVKVPIFEQQKGEA
CEEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]