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The map label for this gene is yvqC [H]

Identifier: 52787183

GI number: 52787183

Start: 3332663

End: 3333298

Strand: Reverse

Name: yvqC [H]

Synonym: BLi03492

Alternate gene names: 52787183

Gene position: 3333298-3332663 (Counterclockwise)

Preceding gene: 52787184

Following gene: 52787178

Centisome position: 78.94

GC content: 49.06

Gene sequence:

>636_bases
GTGATTCGAGTATTGTTAATTGATGATCATGAAATGGTGAGAATGGGGCTGGCCGCTTTCCTGGAATCCCAGCCTGATAT
TGAAGTGATTGGGGAGGCATCAGACGGAAAGCGCGGCGTTGAATTGGCGCTTGAAACCAAACCCGACGTGATTTTGATGG
ATCTTGTGATGGAAGGGATGGACGGAATTGAGGCCACGAAACAAATATGCCGGCAGCTTGCCGATCCGAAAATCATCGTT
CTGACGAGCTTCGTTGATGATGACAAGGTCTATCCGGTCATCGAAGCCGGAGCGCTCAGCTATTTGCTGAAAACGTCGAA
AGCGAGTGAAATCGCCGATGCGATCAGGGCTGCGAGCGTCGGAGAACCAAAGCTTGAAGCCAAAGTCGCAGGAAAAGTGT
TGTCCAAGCTGAGACATTCAGCCGGCGAACAGCCCCTTCATCAATCGCTGACGGCAAGAGAATTGGAAATCCTCAAACTT
GTAGCAGAGGGCAAGACAAACAAAGGTATTGCCGAAGAATTATATATCACCATTAAAACAGTTAAAACGCATGTGACGAA
CATCCTTTCCAAGCTTGAAGTCGACGACCGGACACAAGCCGCAATCTACGCCCACCGAAACAAACTTGTCGACTGA

Upstream 100 bases:

>100_bases
AGTCGGCGGAGTGGCAGAAATCATTTCATTTACGGGAAAAGGAACACAGGTTGATGTAAAGGTTCCGATTTTTGAACAAC
AAAAAGGAGAGGCTTAAAAG

Downstream 100 bases:

>100_bases
TCAAACAAAAAACAGCTTTCTCAAGAAAGCCGTTTTTCAGCCGTTCCAATATTTTCGATCCTCGGCTGCAGGAAGAGTGA
ATGAATCTGTTTCAACCGTG

Product: YvqC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MIRVLLIDDHEMVRMGLAAFLESQPDIEVIGEASDGKRGVELALETKPDVILMDLVMEGMDGIEATKQICRQLADPKIIV
LTSFVDDDKVYPVIEAGALSYLLKTSKASEIADAIRAASVGEPKLEAKVAGKVLSKLRHSAGEQPLHQSLTARELEILKL
VAEGKTNKGIAEELYITIKTVKTHVTNILSKLEVDDRTQAAIYAHRNKLVD

Sequences:

>Translated_211_residues
MIRVLLIDDHEMVRMGLAAFLESQPDIEVIGEASDGKRGVELALETKPDVILMDLVMEGMDGIEATKQICRQLADPKIIV
LTSFVDDDKVYPVIEAGALSYLLKTSKASEIADAIRAASVGEPKLEAKVAGKVLSKLRHSAGEQPLHQSLTARELEILKL
VAEGKTNKGIAEELYITIKTVKTHVTNILSKLEVDDRTQAAIYAHRNKLVD
>Mature_211_residues
MIRVLLIDDHEMVRMGLAAFLESQPDIEVIGEASDGKRGVELALETKPDVILMDLVMEGMDGIEATKQICRQLADPKIIV
LTSFVDDDKVYPVIEAGALSYLLKTSKASEIADAIRAASVGEPKLEAKVAGKVLSKLRHSAGEQPLHQSLTARELEILKL
VAEGKTNKGIAEELYITIKTVKTHVTNILSKLEVDDRTQAAIYAHRNKLVD

Specific function: Member of the two-component regulatory system liaS/liaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin, nisin, ramoplanin and vancomycin). Seems also

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=212, Percent_Identity=36.7924528301887, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1788521, Length=201, Percent_Identity=38.3084577114428, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787473, Length=208, Percent_Identity=37.9807692307692, Blast_Score=113, Evalue=8e-27,
Organism=Escherichia coli, GI1788712, Length=213, Percent_Identity=26.7605633802817, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=30.8457711442786, Blast_Score=78, Evalue=3e-16,
Organism=Escherichia coli, GI1786747, Length=208, Percent_Identity=25.4807692307692, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87082052, Length=104, Percent_Identity=35.5769230769231, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23096; Mature: 23096

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVLLIDDHEMVRMGLAAFLESQPDIEVIGEASDGKRGVELALETKPDVILMDLVMEGM
CEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCEEHHHHHHHCC
DGIEATKQICRQLADPKIIVLTSFVDDDKVYPVIEAGALSYLLKTSKASEIADAIRAASV
CCHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHCC
GEPKLEAKVAGKVLSKLRHSAGEQPLHQSLTARELEILKLVAEGKTNKGIAEELYITIKT
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
VKTHVTNILSKLEVDDRTQAAIYAHRNKLVD
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRVLLIDDHEMVRMGLAAFLESQPDIEVIGEASDGKRGVELALETKPDVILMDLVMEGM
CEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCEEHHHHHHHCC
DGIEATKQICRQLADPKIIVLTSFVDDDKVYPVIEAGALSYLLKTSKASEIADAIRAASV
CCHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHCC
GEPKLEAKVAGKVLSKLRHSAGEQPLHQSLTARELEILKLVAEGKTNKGIAEELYITIKT
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
VKTHVTNILSKLEVDDRTQAAIYAHRNKLVD
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]