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The map label for this gene is yusL [H]

Identifier: 52787157

GI number: 52787157

Start: 3308212

End: 3310602

Strand: Reverse

Name: yusL [H]

Synonym: BLi03466

Alternate gene names: 52787157

Gene position: 3310602-3308212 (Counterclockwise)

Preceding gene: 52787161

Following gene: 52787156

Centisome position: 78.4

GC content: 49.31

Gene sequence:

>2391_bases
ATGGTCAAGCATATTCGAAAAGCCGCCGTTATCGGTTCCGGTGTTATGGGTTCCGGCATCGCGGCTCACTTAGCCAATAT
CGGGATTCCTGTATTACTGCTCGATATGGTGCCGCATGAATTAACAGATGAGGAAAGGAAAAAAGGCCGCACCCTTGAAG
ACCCGGATGTGCGCAATCGGCTGGCACGGACAGCCGTACAAAAGCTGCTAAAGCAAAAACCGGCTCCGCTGACTTCAAAG
AAGAATATCAGCCGTATCAGCACAGGGAACATGGAAGACGATTTTGAAAAGATTAAAGATGCCGACTGGATTATTGAAGT
TGTTGTCGAAAACCTGGAGATCAAAAAGCAAGTGTTTTCAAAGGTCGATCAATACAGAAAACAAGGAAGCATCGTCAGCA
GCAACACATCAGGCATCTCCGTCAGGCAGATGGCTGAGGGAAGGTCCGCTGATTTTAAAAAGCACTTTTTAGGAACGCAC
TTCTTCAATCCGGCCCGCTATTTAAAGCTCCTTGAGGTGATTCCGATTGACGAAACGGAGCCCGAAGTGCTGTCCTTTAT
GAAGAAATTCGGCGAAGACGTTCTTGGCAAAGGGGTTGTTGAAGCGAAAGACACGCCAAACTTTATCGCCAACCGCATCG
GAACCTACGGCTTGCTTGTGACGGTTCAGGAAATGCTGAAAGGCGGCTACACGATAGGCGAAGTCGATTCGATTACAGGT
CCGCTGATCGGACGCCCGAAAAGCGCGACCTTCAGAACGCTCGATGTCGTCGGCCTTGATACATTTTCACACGTTGCCAA
AAATGTCTATAACCAAGTCACGGGCGAAGAAAAAAACGTTTTCCGGCTCCCTGAATTTATTGAACAAATGCTCGAAAAAG
GCTGGATCGGGAGCAAAGCGAAACAAGGTTTTTACAAAAAAGAAGGAAAAGACATCCTTGAGCTCGATCCGATGACGATG
ACCTACAGCGCGCGTCAAACATTAAAAACATCGGGACTGGAAGCGGCCAAGCAAATGAAAGGCGCAGGAGCGAGATTGAA
AGCGCTTGTTTATTCCGATGACAGGGCGGGAAGCCTCCTTTGGAAGATTACAGCTCCGACGCTTGTATATTCGGCGGAGC
TGACAGGGGAAATCGCCGACAGCATAACGGCGGTTGATCAGGCGATGAAATGGGGATTCGGCTGGTCGGAAGGGCCGTTT
GAAATGTGGGACAGCATCGGTGTGAAAAGCTCGGTGCAAAAGCTTGAAGCAGAGGGCTGGAAGGTCGCGGACTGGGTGAA
GGAAATGCTCGCAAAAGGACATGAAACCTTCTACCTTAAGGAAAACGGAAAGACGTTCTACTACTGTTTTGAAAGCGGCG
AATACAGGGCGCTTCAAGAAAACAAGAAAACGATCCATTTGTCGTCACTCAAAGAAACAAAAGGCGTCATCAAGAAAAAC
AGCGGGGCAAGTTTGATCGATTTAGGCGATGATGTCGCACTGCTCGAATTTCACTCGAAAAGCAACGCAATCGGCCTGGA
CATCATTCAAATGCTGAAATTTGCTCTCGAGGAAGTAGACGCCAACTATAAAGGGCTTGTGATCGGCAACCAGGGCAAAA
ATTTCTGCGTCGGAGCCAATCTCGCGATGATGCTGATGGAAGCTCAAGACGACAACTATATGGAAATTGACATGATCATC
CGTCAGTTCCAAGAGACGATGATGAAAGTGAAATACAGTTCCAAGCCGGTCGTCGCTGCTCCGTTCGGCATGACGCTTGG
CGGGGGGACTGAGCTATGCCTGCCTGCTGCCCGTGTTCAAGCCTCAAGCGAATCATACATGGGCCTCGTTGAAACAGGCG
TCGGTCTGATTCCGGGCGGCGGAGGCAATAAAGAGCTTTATTTAAATTACTTGAAAGGGCTGCCTGAAGGCGTTAAACCG
GATATCCAGGAGGCCGCCATCAAGACGTTTGAGACAATTGCCCTTGCAAAAACGTCGACTTCGGCTCAAGAAGCGAAAGA
ACTGAACATCTTAACCGCAGAGGATCAAATCAGCATCAATCAGGATCACTTGTTATACGATGCCAAAAAACTCGTCCTGA
CACTTTCCGAAAGCGGCTACCGTCCGCCGGTGAAAGAGAAAGTTCCGGTGACGGGCGAAACCGGCTATGCGGCGCTCCTG
CTCGGTGCTGAATCGTTAAAACTTTCCGGCGCCATCTCTGAACACGACATGAAGATTGCGAAAAAACTGGCGTTTGTCAT
CGCGGGCGGCCGAGTTCCATTCGGCGCCGAAGTAACGGAAGAATACTTGCTCAATTTGGAAAGAGAAGCGTTTCTGAGCC
TTGTGAGCGAACCGAAATCGCAGGCGAGAATGCAGCATATGCTTGTGAAAGGCAAACCTTTGCGTAATTAG

Upstream 100 bases:

>100_bases
CTCGCTTCCAAAATCTTTTAAGATGAAAGAAGACAGGAGAGTTTATTTTTTTGGAGTAAAAATGAATGAGTATTCATTCA
AAGGTGGGGGAGGATCTTTC

Downstream 100 bases:

>100_bases
GAGGGAAAATAATGAAAGAGGCAGTTATTGTATCGGGGGCGAGAACCCCGATCGGAAAAGCAAAAAAAGGCTCATTGAGG
ACTGTCCGTCCCGATGATTT

Product: YusL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 796; Mature: 796

Protein sequence:

>796_residues
MVKHIRKAAVIGSGVMGSGIAAHLANIGIPVLLLDMVPHELTDEERKKGRTLEDPDVRNRLARTAVQKLLKQKPAPLTSK
KNISRISTGNMEDDFEKIKDADWIIEVVVENLEIKKQVFSKVDQYRKQGSIVSSNTSGISVRQMAEGRSADFKKHFLGTH
FFNPARYLKLLEVIPIDETEPEVLSFMKKFGEDVLGKGVVEAKDTPNFIANRIGTYGLLVTVQEMLKGGYTIGEVDSITG
PLIGRPKSATFRTLDVVGLDTFSHVAKNVYNQVTGEEKNVFRLPEFIEQMLEKGWIGSKAKQGFYKKEGKDILELDPMTM
TYSARQTLKTSGLEAAKQMKGAGARLKALVYSDDRAGSLLWKITAPTLVYSAELTGEIADSITAVDQAMKWGFGWSEGPF
EMWDSIGVKSSVQKLEAEGWKVADWVKEMLAKGHETFYLKENGKTFYYCFESGEYRALQENKKTIHLSSLKETKGVIKKN
SGASLIDLGDDVALLEFHSKSNAIGLDIIQMLKFALEEVDANYKGLVIGNQGKNFCVGANLAMMLMEAQDDNYMEIDMII
RQFQETMMKVKYSSKPVVAAPFGMTLGGGTELCLPAARVQASSESYMGLVETGVGLIPGGGGNKELYLNYLKGLPEGVKP
DIQEAAIKTFETIALAKTSTSAQEAKELNILTAEDQISINQDHLLYDAKKLVLTLSESGYRPPVKEKVPVTGETGYAALL
LGAESLKLSGAISEHDMKIAKKLAFVIAGGRVPFGAEVTEEYLLNLEREAFLSLVSEPKSQARMQHMLVKGKPLRN

Sequences:

>Translated_796_residues
MVKHIRKAAVIGSGVMGSGIAAHLANIGIPVLLLDMVPHELTDEERKKGRTLEDPDVRNRLARTAVQKLLKQKPAPLTSK
KNISRISTGNMEDDFEKIKDADWIIEVVVENLEIKKQVFSKVDQYRKQGSIVSSNTSGISVRQMAEGRSADFKKHFLGTH
FFNPARYLKLLEVIPIDETEPEVLSFMKKFGEDVLGKGVVEAKDTPNFIANRIGTYGLLVTVQEMLKGGYTIGEVDSITG
PLIGRPKSATFRTLDVVGLDTFSHVAKNVYNQVTGEEKNVFRLPEFIEQMLEKGWIGSKAKQGFYKKEGKDILELDPMTM
TYSARQTLKTSGLEAAKQMKGAGARLKALVYSDDRAGSLLWKITAPTLVYSAELTGEIADSITAVDQAMKWGFGWSEGPF
EMWDSIGVKSSVQKLEAEGWKVADWVKEMLAKGHETFYLKENGKTFYYCFESGEYRALQENKKTIHLSSLKETKGVIKKN
SGASLIDLGDDVALLEFHSKSNAIGLDIIQMLKFALEEVDANYKGLVIGNQGKNFCVGANLAMMLMEAQDDNYMEIDMII
RQFQETMMKVKYSSKPVVAAPFGMTLGGGTELCLPAARVQASSESYMGLVETGVGLIPGGGGNKELYLNYLKGLPEGVKP
DIQEAAIKTFETIALAKTSTSAQEAKELNILTAEDQISINQDHLLYDAKKLVLTLSESGYRPPVKEKVPVTGETGYAALL
LGAESLKLSGAISEHDMKIAKKLAFVIAGGRVPFGAEVTEEYLLNLEREAFLSLVSEPKSQARMQHMLVKGKPLRN
>Mature_796_residues
MVKHIRKAAVIGSGVMGSGIAAHLANIGIPVLLLDMVPHELTDEERKKGRTLEDPDVRNRLARTAVQKLLKQKPAPLTSK
KNISRISTGNMEDDFEKIKDADWIIEVVVENLEIKKQVFSKVDQYRKQGSIVSSNTSGISVRQMAEGRSADFKKHFLGTH
FFNPARYLKLLEVIPIDETEPEVLSFMKKFGEDVLGKGVVEAKDTPNFIANRIGTYGLLVTVQEMLKGGYTIGEVDSITG
PLIGRPKSATFRTLDVVGLDTFSHVAKNVYNQVTGEEKNVFRLPEFIEQMLEKGWIGSKAKQGFYKKEGKDILELDPMTM
TYSARQTLKTSGLEAAKQMKGAGARLKALVYSDDRAGSLLWKITAPTLVYSAELTGEIADSITAVDQAMKWGFGWSEGPF
EMWDSIGVKSSVQKLEAEGWKVADWVKEMLAKGHETFYLKENGKTFYYCFESGEYRALQENKKTIHLSSLKETKGVIKKN
SGASLIDLGDDVALLEFHSKSNAIGLDIIQMLKFALEEVDANYKGLVIGNQGKNFCVGANLAMMLMEAQDDNYMEIDMII
RQFQETMMKVKYSSKPVVAAPFGMTLGGGTELCLPAARVQASSESYMGLVETGVGLIPGGGGNKELYLNYLKGLPEGVKP
DIQEAAIKTFETIALAKTSTSAQEAKELNILTAEDQISINQDHLLYDAKKLVLTLSESGYRPPVKEKVPVTGETGYAALL
LGAESLKLSGAISEHDMKIAKKLAFVIAGGRVPFGAEVTEEYLLNLEREAFLSLVSEPKSQARMQHMLVKGKPLRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=308, Percent_Identity=30.1948051948052, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI296179427, Length=325, Percent_Identity=28.9230769230769, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI20127408, Length=303, Percent_Identity=28.3828382838284, Blast_Score=103, Evalue=9e-22,
Organism=Homo sapiens, GI68989263, Length=429, Percent_Identity=24.2424242424242, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI261878539, Length=429, Percent_Identity=24.2424242424242, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1787661, Length=336, Percent_Identity=27.6785714285714, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1790281, Length=225, Percent_Identity=27.5555555555556, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788682, Length=231, Percent_Identity=30.3030303030303, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17553560, Length=309, Percent_Identity=31.3915857605178, Blast_Score=133, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17549919, Length=305, Percent_Identity=31.8032786885246, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17563036, Length=300, Percent_Identity=30.3333333333333, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17508951, Length=457, Percent_Identity=26.4770240700219, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17508953, Length=457, Percent_Identity=26.4770240700219, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI25144276, Length=264, Percent_Identity=30.3030303030303, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17558304, Length=264, Percent_Identity=31.0606060606061, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71985923, Length=305, Percent_Identity=27.5409836065574, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71985930, Length=310, Percent_Identity=25.1612903225806, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24583077, Length=451, Percent_Identity=25.2771618625277, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24583079, Length=451, Percent_Identity=25.2771618625277, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19921000, Length=451, Percent_Identity=25.2771618625277, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45549573, Length=257, Percent_Identity=26.4591439688716, Blast_Score=84, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 87675; Mature: 87675

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKHIRKAAVIGSGVMGSGIAAHLANIGIPVLLLDMVPHELTDEERKKGRTLEDPDVRNR
CCHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHH
LARTAVQKLLKQKPAPLTSKKNISRISTGNMEDDFEKIKDADWIIEVVVENLEIKKQVFS
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVDQYRKQGSIVSSNTSGISVRQMAEGRSADFKKHFLGTHFFNPARYLKLLEVIPIDETE
HHHHHHHCCCEEECCCCCCCHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
PEVLSFMKKFGEDVLGKGVVEAKDTPNFIANRIGTYGLLVTVQEMLKGGYTIGEVDSITG
HHHHHHHHHHCHHHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCC
PLIGRPKSATFRTLDVVGLDTFSHVAKNVYNQVTGEEKNVFRLPEFIEQMLEKGWIGSKA
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCHH
KQGFYKKEGKDILELDPMTMTYSARQTLKTSGLEAAKQMKGAGARLKALVYSDDRAGSLL
HCCCHHHCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEE
WKITAPTLVYSAELTGEIADSITAVDQAMKWGFGWSEGPFEMWDSIGVKSSVQKLEAEGW
EEEECCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHCCC
KVADWVKEMLAKGHETFYLKENGKTFYYCFESGEYRALQENKKTIHLSSLKETKGVIKKN
CHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCEEEHHCCCCEEEEHHHHHHHHHHCCC
SGASLIDLGDDVALLEFHSKSNAIGLDIIQMLKFALEEVDANYKGLVIGNQGKNFCVGAN
CCCCEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCC
LAMMLMEAQDDNYMEIDMIIRQFQETMMKVKYSSKPVVAAPFGMTLGGGTELCLPAARVQ
CEEEEEECCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCCHHCHHHHHH
ASSESYMGLVETGVGLIPGGGGNKELYLNYLKGLPEGVKPDIQEAAIKTFETIALAKTST
CCCHHHHHHHHCCCEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEECCC
SAQEAKELNILTAEDQISINQDHLLYDAKKLVLTLSESGYRPPVKEKVPVTGETGYAALL
CHHHHHHCEEEEECCCCCCCCCHHHHHCCHHEEEECCCCCCCCCCCCCCCCCCCCCEEEE
LGAESLKLSGAISEHDMKIAKKLAFVIAGGRVPFGAEVTEEYLLNLEREAFLSLVSEPKS
ECCHHHEECCCCCHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHCCCHHHHHHHHHCCHH
QARMQHMLVKGKPLRN
HHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVKHIRKAAVIGSGVMGSGIAAHLANIGIPVLLLDMVPHELTDEERKKGRTLEDPDVRNR
CCHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHH
LARTAVQKLLKQKPAPLTSKKNISRISTGNMEDDFEKIKDADWIIEVVVENLEIKKQVFS
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVDQYRKQGSIVSSNTSGISVRQMAEGRSADFKKHFLGTHFFNPARYLKLLEVIPIDETE
HHHHHHHCCCEEECCCCCCCHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
PEVLSFMKKFGEDVLGKGVVEAKDTPNFIANRIGTYGLLVTVQEMLKGGYTIGEVDSITG
HHHHHHHHHHCHHHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCC
PLIGRPKSATFRTLDVVGLDTFSHVAKNVYNQVTGEEKNVFRLPEFIEQMLEKGWIGSKA
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCHH
KQGFYKKEGKDILELDPMTMTYSARQTLKTSGLEAAKQMKGAGARLKALVYSDDRAGSLL
HCCCHHHCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEE
WKITAPTLVYSAELTGEIADSITAVDQAMKWGFGWSEGPFEMWDSIGVKSSVQKLEAEGW
EEEECCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHCCC
KVADWVKEMLAKGHETFYLKENGKTFYYCFESGEYRALQENKKTIHLSSLKETKGVIKKN
CHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCEEEHHCCCCEEEEHHHHHHHHHHCCC
SGASLIDLGDDVALLEFHSKSNAIGLDIIQMLKFALEEVDANYKGLVIGNQGKNFCVGAN
CCCCEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCC
LAMMLMEAQDDNYMEIDMIIRQFQETMMKVKYSSKPVVAAPFGMTLGGGTELCLPAARVQ
CEEEEEECCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCCHHCHHHHHH
ASSESYMGLVETGVGLIPGGGGNKELYLNYLKGLPEGVKPDIQEAAIKTFETIALAKTST
CCCHHHHHHHHCCCEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEECCC
SAQEAKELNILTAEDQISINQDHLLYDAKKLVLTLSESGYRPPVKEKVPVTGETGYAALL
CHHHHHHCEEEEECCCCCCCCCHHHHHCCHHEEEECCCCCCCCCCCCCCCCCCCCCEEEE
LGAESLKLSGAISEHDMKIAKKLAFVIAGGRVPFGAEVTEEYLLNLEREAFLSLVSEPKS
ECCHHHEECCCCCHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHCCCHHHHHHHHHCCHH
QARMQHMLVKGKPLRN
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]