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The map label for this gene is csd [H]

Identifier: 52787141

GI number: 52787141

Start: 3294466

End: 3295686

Strand: Reverse

Name: csd [H]

Synonym: BLi03449

Alternate gene names: 52787141

Gene position: 3295686-3294466 (Counterclockwise)

Preceding gene: 52787142

Following gene: 52787140

Centisome position: 78.05

GC content: 50.04

Gene sequence:

>1221_bases
ATGAATGCTAAAGATATTCGCGAACAGTTTCCGATTCTCAGCCAACAGGTCAACGGACACGATCTCGTTTATTTGGACAG
CGCGGCCACCTCGCAAAAGCCGCGCGTCGTCATTGAGACGCTTGATGAGTATTACAACTCTTACAATTCCAATGTCCATC
GCGGCGTCCATACATTAGGAACAAAAGCAACGGATGGATATGAAGGAGCACGTGAGAAGGTCAGGAAGTTTATAAACGCG
AAATCGATGCAGGAAATTATTTTCACAAGGGGTACGACAACGGCCCTGAACACGGTTGCGCTCAGCTATGCCCGCGCAAA
CCTTAAGCCCGGTGATGAAATCGTCATTACACCGATGGAGCACCATGCGAATATTATTCCGTGGCAGCAGGCTGTCAAAG
CAACCGGCGCCACGCTGAAGTACATTCCGCTTCAGGAAGACGGCACCATTTCCTTGGACGATGTCAGGGAAACGGTGACG
GAAAATACAAAAATCGTCTCTGCAGCGCATGTTTCAAACGTTCTCGGTACGATCAACCCGATTAAGGAAATGGCCAAAAT
CGCCCACGAACACGGCGCGGTCATGGTCGTAGACGGTGCGCAAAGCACGCCGCACATGAAAATTGACGTCCAGGATTTGG
ACTGCGATTTCTATACGTTTTCAGCCCACAAAATGTGTGGTCCGACCGGAATCGGGGTATTGTATGGAAAAAAAGCATTG
CTTGAAAACATGGAACCTGCAGAATTCGGCGGAGAAATGATCGATTTTGTCGGTCTTTACGAATCGACTTGGAAGGAGCT
GCCTTGGAAATTCGAAGCCGGCACACCGATCATTGCCGGCGCGATCGGATTGGGAGCGGCGATTGACTTCCTTGAAGACA
TCGGACTTGATGAAATATTAGCGCATGAACACCGTTTGGCGGCATACGCGCTGGAGCGCTTTAAAGAGCTTGAAGGCGCT
GTTGTCTATGGTCCGGCCGAACGTGCAGGACTCGTGACGTTCAACCTTGAAGACGTTCATCCGCACGATGTGGCAACCGT
GCTGGATGCAGAAGGGGTCGCCGTCAGAGCCGGCCATCACTGCGCGCAGCCTTTAATGAAATGGCTGAACGTCTCCGCCA
CTGCAAGAGCGAGCTTTTATCTGTATAATACGGAAGAAGACATCGACAAACTGATTGAAGCTCTTCAGAAGACAAAGGAG
TATTTCACAAATGTCTTTTAA

Upstream 100 bases:

>100_bases
GCCTCGTCATTTACGGCTTCCTCGCACCGGTTGTCAATGAACTTCCGATTGAAGGCGTGAAGAAGCAGCTGGTCTCTGTG
ATTGAAAGGAAAGTAAAATA

Downstream 100 bases:

>100_bases
TGTGAACTTGGATACACTGTATCGCCAGGTGATTATGGATCACTATAAAAACCCGAGAAATAAAGGGGTTTTGAATGACA
GCATCGTCGTTGACATGAAC

Product: Csd

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MNAKDIREQFPILSQQVNGHDLVYLDSAATSQKPRVVIETLDEYYNSYNSNVHRGVHTLGTKATDGYEGAREKVRKFINA
KSMQEIIFTRGTTTALNTVALSYARANLKPGDEIVITPMEHHANIIPWQQAVKATGATLKYIPLQEDGTISLDDVRETVT
ENTKIVSAAHVSNVLGTINPIKEMAKIAHEHGAVMVVDGAQSTPHMKIDVQDLDCDFYTFSAHKMCGPTGIGVLYGKKAL
LENMEPAEFGGEMIDFVGLYESTWKELPWKFEAGTPIIAGAIGLGAAIDFLEDIGLDEILAHEHRLAAYALERFKELEGA
VVYGPAERAGLVTFNLEDVHPHDVATVLDAEGVAVRAGHHCAQPLMKWLNVSATARASFYLYNTEEDIDKLIEALQKTKE
YFTNVF

Sequences:

>Translated_406_residues
MNAKDIREQFPILSQQVNGHDLVYLDSAATSQKPRVVIETLDEYYNSYNSNVHRGVHTLGTKATDGYEGAREKVRKFINA
KSMQEIIFTRGTTTALNTVALSYARANLKPGDEIVITPMEHHANIIPWQQAVKATGATLKYIPLQEDGTISLDDVRETVT
ENTKIVSAAHVSNVLGTINPIKEMAKIAHEHGAVMVVDGAQSTPHMKIDVQDLDCDFYTFSAHKMCGPTGIGVLYGKKAL
LENMEPAEFGGEMIDFVGLYESTWKELPWKFEAGTPIIAGAIGLGAAIDFLEDIGLDEILAHEHRLAAYALERFKELEGA
VVYGPAERAGLVTFNLEDVHPHDVATVLDAEGVAVRAGHHCAQPLMKWLNVSATARASFYLYNTEEDIDKLIEALQKTKE
YFTNVF
>Mature_406_residues
MNAKDIREQFPILSQQVNGHDLVYLDSAATSQKPRVVIETLDEYYNSYNSNVHRGVHTLGTKATDGYEGAREKVRKFINA
KSMQEIIFTRGTTTALNTVALSYARANLKPGDEIVITPMEHHANIIPWQQAVKATGATLKYIPLQEDGTISLDDVRETVT
ENTKIVSAAHVSNVLGTINPIKEMAKIAHEHGAVMVVDGAQSTPHMKIDVQDLDCDFYTFSAHKMCGPTGIGVLYGKKAL
LENMEPAEFGGEMIDFVGLYESTWKELPWKFEAGTPIIAGAIGLGAAIDFLEDIGLDEILAHEHRLAAYALERFKELEGA
VVYGPAERAGLVTFNLEDVHPHDVATVLDAEGVAVRAGHHCAQPLMKWLNVSATARASFYLYNTEEDIDKLIEALQKTKE
YFTNVF

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=398, Percent_Identity=24.3718592964824, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI156713448, Length=261, Percent_Identity=27.2030651340996, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1787970, Length=393, Percent_Identity=50.1272264631043, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1789175, Length=404, Percent_Identity=42.0792079207921, Blast_Score=321, Evalue=5e-89,
Organism=Escherichia coli, GI48994898, Length=396, Percent_Identity=25.5050505050505, Blast_Score=109, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI25143064, Length=371, Percent_Identity=27.2237196765499, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI193211090, Length=349, Percent_Identity=27.7936962750716, Blast_Score=107, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6319831, Length=391, Percent_Identity=25.5754475703325, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI20129463, Length=314, Percent_Identity=28.9808917197452, Blast_Score=125, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 44790; Mature: 44790

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAKDIREQFPILSQQVNGHDLVYLDSAATSQKPRVVIETLDEYYNSYNSNVHRGVHTLG
CCHHHHHHHCCHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHC
TKATDGYEGAREKVRKFINAKSMQEIIFTRGTTTALNTVALSYARANLKPGDEIVITPME
CCCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEHH
HHANIIPWQQAVKATGATLKYIPLQEDGTISLDDVRETVTENTKIVSAAHVSNVLGTINP
HCCCCCCHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHHCCCEEEHHHHHHHHHHHHHH
IKEMAKIAHEHGAVMVVDGAQSTPHMKIDVQDLDCDFYTFSAHKMCGPTGIGVLYGKKAL
HHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCHHHHCCHHH
LENMEPAEFGGEMIDFVGLYESTWKELPWKFEAGTPIIAGAIGLGAAIDFLEDIGLDEIL
HCCCCHHHHCCHHHHHHHHHHHHHHHCCEEECCCCCEEEHHHHHHHHHHHHHHCCHHHHH
AHEHRLAAYALERFKELEGAVVYGPAERAGLVTFNLEDVHPHDVATVLDAEGVAVRAGHH
HHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEECCCCCCCHHHHHCCCCCCEEECCHH
CAQPLMKWLNVSATARASFYLYNTEEDIDKLIEALQKTKEYFTNVF
HHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNAKDIREQFPILSQQVNGHDLVYLDSAATSQKPRVVIETLDEYYNSYNSNVHRGVHTLG
CCHHHHHHHCCHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHC
TKATDGYEGAREKVRKFINAKSMQEIIFTRGTTTALNTVALSYARANLKPGDEIVITPME
CCCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEHH
HHANIIPWQQAVKATGATLKYIPLQEDGTISLDDVRETVTENTKIVSAAHVSNVLGTINP
HCCCCCCHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHHCCCEEEHHHHHHHHHHHHHH
IKEMAKIAHEHGAVMVVDGAQSTPHMKIDVQDLDCDFYTFSAHKMCGPTGIGVLYGKKAL
HHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCHHHHCCHHH
LENMEPAEFGGEMIDFVGLYESTWKELPWKFEAGTPIIAGAIGLGAAIDFLEDIGLDEIL
HCCCCHHHHCCHHHHHHHHHHHHHHHCCEEECCCCCEEEHHHHHHHHHHHHHHCCHHHHH
AHEHRLAAYALERFKELEGAVVYGPAERAGLVTFNLEDVHPHDVATVLDAEGVAVRAGHH
HHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEEECCCCCCCHHHHHCCCCCCEEECCHH
CAQPLMKWLNVSATARASFYLYNTEEDIDKLIEALQKTKEYFTNVF
HHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]