Click here to switch to the map view.

The map label for this gene is yugS [H]

Identifier: 52787003

GI number: 52787003

Start: 3169851

End: 3171140

Strand: Reverse

Name: yugS [H]

Synonym: BLi03305

Alternate gene names: 52787003

Gene position: 3171140-3169851 (Counterclockwise)

Preceding gene: 52787004

Following gene: 52787002

Centisome position: 75.1

GC content: 44.42

Gene sequence:

>1290_bases
TTGAATATCCTGAATCTCATACTCGTCATACTTTTAATTGCAGCTACGGCTTTTTTCGTTGTCGCCGAATTTGCGATCGT
CAAAATCCGCGGCACAAAAATCGATCAGCTCGTTGAAAGCGGGGATAAGCGGGCGATTGCGGCCAAAAGAGTGGTGACAA
ATCTTGATGAATATTTGTCTGCCTGCCAGCTCGGCATTACCATCACCGCATTAGGGCTCGGCTGGCTCGGAGAATCGACA
TTCGAACAGATCATTCACCCGCTTTTTGAGTTATTTGGCCTGCCTGAGTCCGTTTTAAGAGTGGCTTCGGTTGTTGCCGC
ATTTATCATCATTACATTTTTGCACGTTGTGGTCGGCGAGCTTGCGCCAAAAACAATTGCGATTCAAAAAGCGGAAGCCG
TCAGCTTATGGACGGCGAAGCCGCTCATTTTGTTTTATAAAATCATGTTTCCGTTTATCAAACTGTTGAATGGCTCGGCC
CGGCTGTTAACGAAGCTGTTCGGGTTCCATTCTGTTAAAGAGCATGAAGTGGCGATCAGTGAGGAAGAGCTGCGGCTTAT
GCTGTCTGAAAGCTATAAAAAAGGGGAAATCAATCAGTCTGAGTATAAATACGTCAACAAAATTTTTGAATTTGACAACA
GGCTGGCCCGGGAAATCATGGTGCCGAGAACGGAGATGGCGACGCTTATGGCCGATCAATCCATAAAAGAAGCGATTGAA
ACCGTCATTAATGAACGCTACACGAGATATCCGGTTATTAAGGACGATAAAGACCATATTATCGGAATTGTCAACAGCAA
GGACTTGTTTAAATCGTATTTTCTCGACGAGACGATTCCTTTAACTGACTTAATGAGGCCTGTCATCAGGGTGATTGAGA
ACATACCGATCCAGGAGCTCTTGATTCGCATGCAGAAGGAACGGATCCATATGGCCATTCTTGTTGATGAGTACGGCGGA
ACGGCAGGGCTGGTTACGGTAGAAGACATATTAGAGGAAATCGTCGGAGAAATCAGGGATGAGTTTGATCAGGACGAAAT
GCCGCACATTATAAAAAAAGGCGAACATCATTATATTATGGACGGAAAAGCTTTAATCGACGAAGTGAATGACCTCCTTC
ATATCGCGATAGAAAACGAAGAAGTCGATACGATCGCCGGCTGGCTTTTGACGCAAAAGATGGAGCTGAAAAACGGGGAC
ATCCTTAAAACTGAGGGGTGCGAATTTAAAATTCTTGATGCTGAAGATCATCATATCCGTTTCATCGAAGTGAAAAAAAC
GGATTTTTAA

Upstream 100 bases:

>100_bases
TTGAGCTGCTGCGCTTCGTCGCAATTTTCCTGTCCGGTCGTAATGACTAACCATTCGTTTTAAGGAGGTGGCCCCTTACC
ATATTTGGTAAGGGCTTTTT

Downstream 100 bases:

>100_bases
AAACAGCTGCGGTTGGCCGCGGCTGTTTTTTAGTTCGATGGCCGTTCCTTATTTCAATAAAATGGATATTTATTCAAAGA
TAAGAGGATATATCTATGGA

Product: YugS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MNILNLILVILLIAATAFFVVAEFAIVKIRGTKIDQLVESGDKRAIAAKRVVTNLDEYLSACQLGITITALGLGWLGEST
FEQIIHPLFELFGLPESVLRVASVVAAFIIITFLHVVVGELAPKTIAIQKAEAVSLWTAKPLILFYKIMFPFIKLLNGSA
RLLTKLFGFHSVKEHEVAISEEELRLMLSESYKKGEINQSEYKYVNKIFEFDNRLAREIMVPRTEMATLMADQSIKEAIE
TVINERYTRYPVIKDDKDHIIGIVNSKDLFKSYFLDETIPLTDLMRPVIRVIENIPIQELLIRMQKERIHMAILVDEYGG
TAGLVTVEDILEEIVGEIRDEFDQDEMPHIIKKGEHHYIMDGKALIDEVNDLLHIAIENEEVDTIAGWLLTQKMELKNGD
ILKTEGCEFKILDAEDHHIRFIEVKKTDF

Sequences:

>Translated_429_residues
MNILNLILVILLIAATAFFVVAEFAIVKIRGTKIDQLVESGDKRAIAAKRVVTNLDEYLSACQLGITITALGLGWLGEST
FEQIIHPLFELFGLPESVLRVASVVAAFIIITFLHVVVGELAPKTIAIQKAEAVSLWTAKPLILFYKIMFPFIKLLNGSA
RLLTKLFGFHSVKEHEVAISEEELRLMLSESYKKGEINQSEYKYVNKIFEFDNRLAREIMVPRTEMATLMADQSIKEAIE
TVINERYTRYPVIKDDKDHIIGIVNSKDLFKSYFLDETIPLTDLMRPVIRVIENIPIQELLIRMQKERIHMAILVDEYGG
TAGLVTVEDILEEIVGEIRDEFDQDEMPHIIKKGEHHYIMDGKALIDEVNDLLHIAIENEEVDTIAGWLLTQKMELKNGD
ILKTEGCEFKILDAEDHHIRFIEVKKTDF
>Mature_429_residues
MNILNLILVILLIAATAFFVVAEFAIVKIRGTKIDQLVESGDKRAIAAKRVVTNLDEYLSACQLGITITALGLGWLGEST
FEQIIHPLFELFGLPESVLRVASVVAAFIIITFLHVVVGELAPKTIAIQKAEAVSLWTAKPLILFYKIMFPFIKLLNGSA
RLLTKLFGFHSVKEHEVAISEEELRLMLSESYKKGEINQSEYKYVNKIFEFDNRLAREIMVPRTEMATLMADQSIKEAIE
TVINERYTRYPVIKDDKDHIIGIVNSKDLFKSYFLDETIPLTDLMRPVIRVIENIPIQELLIRMQKERIHMAILVDEYGG
TAGLVTVEDILEEIVGEIRDEFDQDEMPHIIKKGEHHYIMDGKALIDEVNDLLHIAIENEEVDTIAGWLLTQKMELKNGD
ILKTEGCEFKILDAEDHHIRFIEVKKTDF

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=401, Percent_Identity=47.6309226932668, Blast_Score=394, Evalue=1e-109,
Organism=Escherichia coli, GI1790664, Length=435, Percent_Identity=24.1379310344828, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1786879, Length=269, Percent_Identity=32.3420074349442, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI145693175, Length=417, Percent_Identity=24.220623501199, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1788119, Length=237, Percent_Identity=27.0042194092827, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082033, Length=242, Percent_Identity=23.5537190082645, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324512, Length=260, Percent_Identity=23.4615384615385, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48866; Mature: 48866

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILNLILVILLIAATAFFVVAEFAIVKIRGTKIDQLVESGDKRAIAAKRVVTNLDEYLS
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ACQLGITITALGLGWLGESTFEQIIHPLFELFGLPESVLRVASVVAAFIIITFLHVVVGE
HHHHCHHHEEHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAPKTIAIQKAEAVSLWTAKPLILFYKIMFPFIKLLNGSARLLTKLFGFHSVKEHEVAIS
CCCCCEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHCC
EEELRLMLSESYKKGEINQSEYKYVNKIFEFDNRLAREIMVPRTEMATLMADQSIKEAIE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
TVINERYTRYPVIKDDKDHIIGIVNSKDLFKSYFLDETIPLTDLMRPVIRVIENIPIQEL
HHHHCCHHCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHH
LIRMQKERIHMAILVDEYGGTAGLVTVEDILEEIVGEIRDEFDQDEMPHIIKKGEHHYIM
HHHHHHHHEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEE
DGKALIDEVNDLLHIAIENEEVDTIAGWLLTQKMELKNGDILKTEGCEFKILDAEDHHIR
CCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCEEE
FIEVKKTDF
EEEEECCCC
>Mature Secondary Structure
MNILNLILVILLIAATAFFVVAEFAIVKIRGTKIDQLVESGDKRAIAAKRVVTNLDEYLS
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ACQLGITITALGLGWLGESTFEQIIHPLFELFGLPESVLRVASVVAAFIIITFLHVVVGE
HHHHCHHHEEHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAPKTIAIQKAEAVSLWTAKPLILFYKIMFPFIKLLNGSARLLTKLFGFHSVKEHEVAIS
CCCCCEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHCC
EEELRLMLSESYKKGEINQSEYKYVNKIFEFDNRLAREIMVPRTEMATLMADQSIKEAIE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
TVINERYTRYPVIKDDKDHIIGIVNSKDLFKSYFLDETIPLTDLMRPVIRVIENIPIQEL
HHHHCCHHCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHH
LIRMQKERIHMAILVDEYGGTAGLVTVEDILEEIVGEIRDEFDQDEMPHIIKKGEHHYIM
HHHHHHHHEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEE
DGKALIDEVNDLLHIAIENEEVDTIAGWLLTQKMELKNGDILKTEGCEFKILDAEDHHIR
CCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCEEE
FIEVKKTDF
EEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]