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The map label for this gene is yubD [H]

Identifier: 52786822

GI number: 52786822

Start: 2980133

End: 2981755

Strand: Reverse

Name: yubD [H]

Synonym: BLi03096

Alternate gene names: 52786822

Gene position: 2981755-2980133 (Counterclockwise)

Preceding gene: 52786823

Following gene: 52786821

Centisome position: 70.61

GC content: 47.26

Gene sequence:

>1623_bases
ATGAGTCAATCTGATGTGGCGATCCCGAGCTCTAAAAAAATCGGCATTCCGAAGTATTTGATCATTTCGGTTTTAACGAT
ACTGGCCATTGGGCCGCAATATTTTCTTAATCTTTCCTATACGCTCAGTCAAGTCGTCATTCAAAACGGACTTCATTTGT
CACCGGACGATATGCGGATTCCGTCCATTTTGACAAATCTTGCTTTTGCTCTCGGTGTTCCGCTTGGACGTATATTTTCA
AGGAGGTTCGGCATTCGGAACAGCTACCTGACACTCATCACCTTATTTTTATGCGGCTCGCTGATCGACGCATTTTCAGC
AGGCTTGTTTTCGCTTCTTATCGGAAGGGTGATACAAGGATTATGCTCCGGAATGTTATTTTTGACGATTCTTCCTGTCA
AATTGATTTCGTTTCCGAACAAGGTCCGCAATTTGTTTTTGTTTTTCGTCATTAGCGGATTGTTCGGCGCTTCTGCCATC
GGAGCGGTTTTTGGTTCCCTGTCACTCAGCGCGGATGCATGGCGCTGGGTGTTTATATTAAATATTTGTTCGCCTGTCCT
TTGCCTTGTGATCGGCTTCTTTTCTTTGCCGAAACAAGCAGCGGATGAGCGGGAGCATCATTCGATTGATAAGACGGGCG
TTTTTATGCTCTCATTGCTCATGGTTGTTTTGACGGTGCCGCTTATCAATTTGCAGAAGACGGGTGTTCATTCTTTTTAT
GTGTGGCCGTTCTTTTTGGCCGGATTCATCATTTTGGCGTTGTTTGTCATTACAGACTTGCGCGCCCGGGAACCTCTTGT
GCCGTTTCGTTCACTGTGGTCCGCAAAAGCTGTTTCCGGGACAGTCATGGCCGTTGCTTCACACATTGCAATCATTGTTT
CCCTTGCCGGGATAAACGGATTTTTGGAAAACATTGCAGAGGCTTCTTTTGAAAGCATGACACGCTTTTATTTGTGTTTT
TTCGCAGGGATTTTAGCTACTGCCGTGCTCAGCACGCTTTTGTATGATCATTTTGGCGCCGGATTGCTCGGCTGTATCGG
CGCTTTGGAAATGATCATCGTCGGTATGGAATGGAGATCGGTTCAACCCGGTGTTTCGATGGAGTCGTTATATCTTCATG
CTGTTTTGCTGGGCAGCGGCGTCAGCATGGTATTGGTATCGGGAGCGCTGGGCACGGCGCTTGCCGGAGATATTCACCAA
GCTTCAAAACGCTCGGTTTCGCTTCACTTTATCCGCAATTTCGCCGGTGCCTGGGCTGCACCGGTGATCGGCTGGTTTGC
TTCAATGAAGAATGCGGTGCACTACGAGATGATAAGAGGACATATCAGTGAAGCTGATCCTGAAATTCAGCTGGAATTGT
CAAAAATGATTCGTGATTTTGTCAGCAGCGGGCTTTCTGTTGGTGATGCGAAGAACATGGCGGCCTATACGATTGTTGCA
AATGCCAGAAAAGCTTCAGCCCTTGGCGCATATCACGATTTGTTTACGATACTGCTCTGGCTAAGCATCATCATGCTTGC
GGCTTCAATTGGAAAGGCAGCGACCGGAAAAGGAAGATCGCTCGTTCAGAAGCGCCTTCGCCTGCCAGACCCTTCAGCAA
GTCAACAAAAGGAGATAGGATAA

Upstream 100 bases:

>100_bases
TTTCTTTTTCTTTCGGTTGAATTATTGCGGGAAGGATGTATAATTTAACTTGCATAATACAACTTGTAATATGAAATATA
TAACTAAAGGAGGAGCGCTT

Downstream 100 bases:

>100_bases
ACATGAGTAAAGGACGTTTGATGATCATCAATATGATTGGTATTATCGCAACTTTAGCGCTTGTCGCTGTATGCGGATAT
TACTATTATCAAAATAAACA

Product: YubD

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 539

Protein sequence:

>540_residues
MSQSDVAIPSSKKIGIPKYLIISVLTILAIGPQYFLNLSYTLSQVVIQNGLHLSPDDMRIPSILTNLAFALGVPLGRIFS
RRFGIRNSYLTLITLFLCGSLIDAFSAGLFSLLIGRVIQGLCSGMLFLTILPVKLISFPNKVRNLFLFFVISGLFGASAI
GAVFGSLSLSADAWRWVFILNICSPVLCLVIGFFSLPKQAADEREHHSIDKTGVFMLSLLMVVLTVPLINLQKTGVHSFY
VWPFFLAGFIILALFVITDLRAREPLVPFRSLWSAKAVSGTVMAVASHIAIIVSLAGINGFLENIAEASFESMTRFYLCF
FAGILATAVLSTLLYDHFGAGLLGCIGALEMIIVGMEWRSVQPGVSMESLYLHAVLLGSGVSMVLVSGALGTALAGDIHQ
ASKRSVSLHFIRNFAGAWAAPVIGWFASMKNAVHYEMIRGHISEADPEIQLELSKMIRDFVSSGLSVGDAKNMAAYTIVA
NARKASALGAYHDLFTILLWLSIIMLAASIGKAATGKGRSLVQKRLRLPDPSASQQKEIG

Sequences:

>Translated_540_residues
MSQSDVAIPSSKKIGIPKYLIISVLTILAIGPQYFLNLSYTLSQVVIQNGLHLSPDDMRIPSILTNLAFALGVPLGRIFS
RRFGIRNSYLTLITLFLCGSLIDAFSAGLFSLLIGRVIQGLCSGMLFLTILPVKLISFPNKVRNLFLFFVISGLFGASAI
GAVFGSLSLSADAWRWVFILNICSPVLCLVIGFFSLPKQAADEREHHSIDKTGVFMLSLLMVVLTVPLINLQKTGVHSFY
VWPFFLAGFIILALFVITDLRAREPLVPFRSLWSAKAVSGTVMAVASHIAIIVSLAGINGFLENIAEASFESMTRFYLCF
FAGILATAVLSTLLYDHFGAGLLGCIGALEMIIVGMEWRSVQPGVSMESLYLHAVLLGSGVSMVLVSGALGTALAGDIHQ
ASKRSVSLHFIRNFAGAWAAPVIGWFASMKNAVHYEMIRGHISEADPEIQLELSKMIRDFVSSGLSVGDAKNMAAYTIVA
NARKASALGAYHDLFTILLWLSIIMLAASIGKAATGKGRSLVQKRLRLPDPSASQQKEIG
>Mature_539_residues
SQSDVAIPSSKKIGIPKYLIISVLTILAIGPQYFLNLSYTLSQVVIQNGLHLSPDDMRIPSILTNLAFALGVPLGRIFSR
RFGIRNSYLTLITLFLCGSLIDAFSAGLFSLLIGRVIQGLCSGMLFLTILPVKLISFPNKVRNLFLFFVISGLFGASAIG
AVFGSLSLSADAWRWVFILNICSPVLCLVIGFFSLPKQAADEREHHSIDKTGVFMLSLLMVVLTVPLINLQKTGVHSFYV
WPFFLAGFIILALFVITDLRAREPLVPFRSLWSAKAVSGTVMAVASHIAIIVSLAGINGFLENIAEASFESMTRFYLCFF
AGILATAVLSTLLYDHFGAGLLGCIGALEMIIVGMEWRSVQPGVSMESLYLHAVLLGSGVSMVLVSGALGTALAGDIHQA
SKRSVSLHFIRNFAGAWAAPVIGWFASMKNAVHYEMIRGHISEADPEIQLELSKMIRDFVSSGLSVGDAKNMAAYTIVAN
ARKASALGAYHDLFTILLWLSIIMLAASIGKAATGKGRSLVQKRLRLPDPSASQQKEIG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1790195, Length=222, Percent_Identity=26.1261261261261, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 58385; Mature: 58254

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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>Mature Secondary Structure 
SQSDVAIPSSKKIGIPKYLIISVLTILAIGPQYFLNLSYTLSQVVIQNGLHLSPDDMRI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCHH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PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]