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The map label for this gene is mepA [H]

Identifier: 52786552

GI number: 52786552

Start: 2701479

End: 2702834

Strand: Direct

Name: mepA [H]

Synonym: BLi02817

Alternate gene names: 52786552

Gene position: 2701479-2702834 (Clockwise)

Preceding gene: 52786551

Following gene: 52786553

Centisome position: 63.98

GC content: 46.39

Gene sequence:

>1356_bases
ATGATGACAGAAACACATCAGCAGCTCATGAAATTACCAGTAAATCAAGTGTTTTTTAAATATTTCGTCCCTGCAACGCT
TGGATTAATCCTGATGTCAGCGAATATTTTAATTGATGGCCTGTTCGTAGGCAATGGCATTGGAACCGCAGCACTGGCTG
GAGTGAACCTTTCCTATCCGGTTATTTCACTCATTATGGCCATCGCTCTTTGGATTGGGATAGGCGGAGCAACAAAGTAC
TCCATCAGCATCGGGGAGAATCGCCCCAAGAAGGCCAGCAGCATTTTTTCATTGGCTCTCTTCTTGGCGCTTATCATCAG
CGTGCTTTTAGGAGTATTCGGGATTCTCAACATTCAAACCATTTCGATATGGCTTGGTGCCAACTCCGACACCTCTTCTT
TTGTCATAGAGTACTTAAGTGTCATGTTTTTATTCGGCTGGGTCATTACATTAGAACAGGTCTTAAGTATTTTTGTAAGG
AATGACGGCAGTCCGAAGCTTTCGATGATGGCTCTTGCAACGACATCGATTGTGAATATCATTCTGAATTTTTATACGAT
CATGATTTTGGACATGGGGGTAACAGGCGCTGCGATTTCAACGGTGCTTGGCGGATTCGCCGGACTGCTTGTATTATCCC
TGCACTTCTTCAACCGTCAAGCGCAACTGAGAAGGCCGGCGTTTCAGTGGTCTTGGAAATCCCTTATGCACATCTTTGCC
ATCGGGTTTCCAAGCTTTCTGGCAGAGGCCGGGCTCCTCGTATTTGTTACAGGATACAACTTGGCAATGGCAAGCCTGGC
AGGCACGGAAGGAGTCGCTGCCTTCTCGGTCATTAACTACCTTCACGGGTTCATGTTCCTGTCCTTCTTCGGCATTGAAA
TGGCACTTCAGCCCATGATTAGCTATTATCATGGTGCTGAAGAAACCGAACAAATCAAAAGCAGCATGAAGATTGGGGAG
AAGACCGCCGTAATCCTGGGCATACTTTTGCTCGTTATCGGCTGGGGGGCTGCCCCATTCCTTGTAGGCTTATTCGGAAT
AGAATCAACCGAAATCCAGCAGCTGGCCATCGATGGAATCCGCCTGTTTTTTATCGGCTATACCTTCCTTGGCTATAACT
TTGTCTATATGAGTTACTTTCAATCTATTGGCCGGGCCGGCTCATCGGTTGTTATCATTATATTGCGAAGCTTCGTGTCC
CTGTTCATCCTGCTTTGGATTTTGCCAAAGTTTATTGGCGTCACGGGAGTTTGGCTATCCTTGCCGCTTTCCGAGTTTTT
TGTTGCCGTCCTCCTCTTTTTCATTGCAAGAAAACATGTGATGGGAAAAGGAAATCCCGCTATCGGGAAGGGATGA

Upstream 100 bases:

>100_bases
ATGTCACTTTAATCCAAATTCCGGTAACAAAGAGTTTTGATTGACCTTCAAGTAACTTGAAGGTTTAGAATACTCCTGTA
GCTCATTATAGGAGGAATAC

Downstream 100 bases:

>100_bases
TTTTACAGCCGGGAGATTTTCCCCGCTTGTTGTCCTATAGAACTTAATTTGTCCATTCAAGGAAAAGAAATGTTTGTGCT
GTTTGAATCCCCTCCTATTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MMTETHQQLMKLPVNQVFFKYFVPATLGLILMSANILIDGLFVGNGIGTAALAGVNLSYPVISLIMAIALWIGIGGATKY
SISIGENRPKKASSIFSLALFLALIISVLLGVFGILNIQTISIWLGANSDTSSFVIEYLSVMFLFGWVITLEQVLSIFVR
NDGSPKLSMMALATTSIVNIILNFYTIMILDMGVTGAAISTVLGGFAGLLVLSLHFFNRQAQLRRPAFQWSWKSLMHIFA
IGFPSFLAEAGLLVFVTGYNLAMASLAGTEGVAAFSVINYLHGFMFLSFFGIEMALQPMISYYHGAEETEQIKSSMKIGE
KTAVILGILLLVIGWGAAPFLVGLFGIESTEIQQLAIDGIRLFFIGYTFLGYNFVYMSYFQSIGRAGSSVVIIILRSFVS
LFILLWILPKFIGVTGVWLSLPLSEFFVAVLLFFIARKHVMGKGNPAIGKG

Sequences:

>Translated_451_residues
MMTETHQQLMKLPVNQVFFKYFVPATLGLILMSANILIDGLFVGNGIGTAALAGVNLSYPVISLIMAIALWIGIGGATKY
SISIGENRPKKASSIFSLALFLALIISVLLGVFGILNIQTISIWLGANSDTSSFVIEYLSVMFLFGWVITLEQVLSIFVR
NDGSPKLSMMALATTSIVNIILNFYTIMILDMGVTGAAISTVLGGFAGLLVLSLHFFNRQAQLRRPAFQWSWKSLMHIFA
IGFPSFLAEAGLLVFVTGYNLAMASLAGTEGVAAFSVINYLHGFMFLSFFGIEMALQPMISYYHGAEETEQIKSSMKIGE
KTAVILGILLLVIGWGAAPFLVGLFGIESTEIQQLAIDGIRLFFIGYTFLGYNFVYMSYFQSIGRAGSSVVIIILRSFVS
LFILLWILPKFIGVTGVWLSLPLSEFFVAVLLFFIARKHVMGKGNPAIGKG
>Mature_451_residues
MMTETHQQLMKLPVNQVFFKYFVPATLGLILMSANILIDGLFVGNGIGTAALAGVNLSYPVISLIMAIALWIGIGGATKY
SISIGENRPKKASSIFSLALFLALIISVLLGVFGILNIQTISIWLGANSDTSSFVIEYLSVMFLFGWVITLEQVLSIFVR
NDGSPKLSMMALATTSIVNIILNFYTIMILDMGVTGAAISTVLGGFAGLLVLSLHFFNRQAQLRRPAFQWSWKSLMHIFA
IGFPSFLAEAGLLVFVTGYNLAMASLAGTEGVAAFSVINYLHGFMFLSFFGIEMALQPMISYYHGAEETEQIKSSMKIGE
KTAVILGILLLVIGWGAAPFLVGLFGIESTEIQQLAIDGIRLFFIGYTFLGYNFVYMSYFQSIGRAGSSVVIIILRSFVS
LFILLWILPKFIGVTGVWLSLPLSEFFVAVLLFFIARKHVMGKGNPAIGKG

Specific function: Multidrug resistance efflux protein [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49153; Mature: 49153

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTETHQQLMKLPVNQVFFKYFVPATLGLILMSANILIDGLFVGNGIGTAALAGVNLSYP
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHCCCCCHH
VISLIMAIALWIGIGGATKYSISIGENRPKKASSIFSLALFLALIISVLLGVFGILNIQT
HHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
ISIWLGANSDTSSFVIEYLSVMFLFGWVITLEQVLSIFVRNDGSPKLSMMALATTSIVNI
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ILNFYTIMILDMGVTGAAISTVLGGFAGLLVLSLHFFNRQAQLRRPAFQWSWKSLMHIFA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHH
IGFPSFLAEAGLLVFVTGYNLAMASLAGTEGVAAFSVINYLHGFMFLSFFGIEMALQPMI
HCCHHHHHCCCEEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYYHGAEETEQIKSSMKIGEKTAVILGILLLVIGWGAAPFLVGLFGIESTEIQQLAIDGI
HHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHH
RLFFIGYTFLGYNFVYMSYFQSIGRAGSSVVIIILRSFVSLFILLWILPKFIGVTGVWLS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPLSEFFVAVLLFFIARKHVMGKGNPAIGKG
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MMTETHQQLMKLPVNQVFFKYFVPATLGLILMSANILIDGLFVGNGIGTAALAGVNLSYP
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHCCCCCHH
VISLIMAIALWIGIGGATKYSISIGENRPKKASSIFSLALFLALIISVLLGVFGILNIQT
HHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
ISIWLGANSDTSSFVIEYLSVMFLFGWVITLEQVLSIFVRNDGSPKLSMMALATTSIVNI
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ILNFYTIMILDMGVTGAAISTVLGGFAGLLVLSLHFFNRQAQLRRPAFQWSWKSLMHIFA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHH
IGFPSFLAEAGLLVFVTGYNLAMASLAGTEGVAAFSVINYLHGFMFLSFFGIEMALQPMI
HCCHHHHHCCCEEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYYHGAEETEQIKSSMKIGEKTAVILGILLLVIGWGAAPFLVGLFGIESTEIQQLAIDGI
HHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHH
RLFFIGYTFLGYNFVYMSYFQSIGRAGSSVVIIILRSFVSLFILLWILPKFIGVTGVWLS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPLSEFFVAVLLFFIARKHVMGKGNPAIGKG
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA