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The map label for this gene is des [H]

Identifier: 52786542

GI number: 52786542

Start: 2690849

End: 2691907

Strand: Direct

Name: des [H]

Synonym: BLi02807

Alternate gene names: 52786542

Gene position: 2690849-2691907 (Clockwise)

Preceding gene: 52786535

Following gene: 52786543

Centisome position: 63.72

GC content: 43.44

Gene sequence:

>1059_bases
ATGACTGAACAAACCATTGCCCATAAACAAAAACAGTTGACAAAACAGGTTGCTGCGTTTGCACAGCCTGATACCAAGAA
CAGTCTGCTTCAGCTTTTGAATACGTTTATTCCTTTCTTCGGACTGTGGTTTCTTGCCTATTTCAGCCTCAATGTCTCCT
ATCTCCTTACTTTAGGAATAACGGTGATTGCCGCAGGGTTTTTGACGAGAATTTTCATTATTTTTCACGACTGCTGCCAT
TTATCCTTTTTCAAACAAAAACGCCTTAACCATATTCTCGGTTTTTTGACAGGCGTTCTGACTTTATTTCCTTATCTTCA
ATGGCAGCACAGCCATTCGATTCATCATGCGACAAGCAGCAACCTGGATAAACGGGGAACGGGTGACATCTGGCTGCTGA
CGGTAAATGAATATAAAGCCGCACCTCTGCGCACAAAAATCGCATACAGACTTTACAGAAATCCGTTTATCATGTTTATT
CTCGGACCGATTTATGTCTTTCTGATCACAAACCGCTTTAACAAAAAAGGAGCAAGACGGAAAGAGCGTGTGAACACATA
CCTCACCAACCTTGCAATCGCGGCATTGGCTGCTGTCTGCTGCCTGATTTTTGGCTGGCAATCATTTTTGCTCGTACAAG
GTCCGATCTTTCTGATCTCAGGTTCGATCGGCGTTTGGCTGTTTTATGTTCAGCACACATTTGAAGATTCTTATTTTGAA
GCGGATGAAAATTGGAGCTATGTTCAGGCCGCTGTGGAAGGAAGTTCGTTTTATAAACTCCCGAAACTGCTTCAATGGCT
TACAGGCAATATCGGGTACCACCATGTTCACCATCTCAGTCCAAAGGTGCCTAACTATAAACTTGAAACCGCACATGAAC
AGCACGAACCTTTAAAAAACGTCCCGACCATCACTTTGAAAACAAGCCTGCAATCACTCGCGTTCCGGCTTTGGGATGAA
GAAAAAAAGCAATTTGTAACCTTTCGGGACATGAAACAAACATCTTCCCATCCTTCGCCGGATTCAACGAAAAAACAGAA
GCTGCGGAAGAACGCCTGA

Upstream 100 bases:

>100_bases
GACAAGTGTCATGTTTGAAGCATGATGTGTGCTACTACAAAGACATCTCTCTGTGCCGTAAACTTAATTTAAGACCTATT
TATGAGAGGATAACTTTACT

Downstream 100 bases:

>100_bases
CGATAAGGAGGTCTTCTTATATCAACAAGAAGACTTCCTTTTTATTGTCCGATGATGCAATCAGGCTCCGGCAATGGTAA
AGTTACTCTAAAGATGAAAA

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTEQTIAHKQKQLTKQVAAFAQPDTKNSLLQLLNTFIPFFGLWFLAYFSLNVSYLLTLGITVIAAGFLTRIFIIFHDCCH
LSFFKQKRLNHILGFLTGVLTLFPYLQWQHSHSIHHATSSNLDKRGTGDIWLLTVNEYKAAPLRTKIAYRLYRNPFIMFI
LGPIYVFLITNRFNKKGARRKERVNTYLTNLAIAALAAVCCLIFGWQSFLLVQGPIFLISGSIGVWLFYVQHTFEDSYFE
ADENWSYVQAAVEGSSFYKLPKLLQWLTGNIGYHHVHHLSPKVPNYKLETAHEQHEPLKNVPTITLKTSLQSLAFRLWDE
EKKQFVTFRDMKQTSSHPSPDSTKKQKLRKNA

Sequences:

>Translated_352_residues
MTEQTIAHKQKQLTKQVAAFAQPDTKNSLLQLLNTFIPFFGLWFLAYFSLNVSYLLTLGITVIAAGFLTRIFIIFHDCCH
LSFFKQKRLNHILGFLTGVLTLFPYLQWQHSHSIHHATSSNLDKRGTGDIWLLTVNEYKAAPLRTKIAYRLYRNPFIMFI
LGPIYVFLITNRFNKKGARRKERVNTYLTNLAIAALAAVCCLIFGWQSFLLVQGPIFLISGSIGVWLFYVQHTFEDSYFE
ADENWSYVQAAVEGSSFYKLPKLLQWLTGNIGYHHVHHLSPKVPNYKLETAHEQHEPLKNVPTITLKTSLQSLAFRLWDE
EKKQFVTFRDMKQTSSHPSPDSTKKQKLRKNA
>Mature_351_residues
TEQTIAHKQKQLTKQVAAFAQPDTKNSLLQLLNTFIPFFGLWFLAYFSLNVSYLLTLGITVIAAGFLTRIFIIFHDCCHL
SFFKQKRLNHILGFLTGVLTLFPYLQWQHSHSIHHATSSNLDKRGTGDIWLLTVNEYKAAPLRTKIAYRLYRNPFIMFIL
GPIYVFLITNRFNKKGARRKERVNTYLTNLAIAALAAVCCLIFGWQSFLLVQGPIFLISGSIGVWLFYVQHTFEDSYFEA
DENWSYVQAAVEGSSFYKLPKLLQWLTGNIGYHHVHHLSPKVPNYKLETAHEQHEPLKNVPTITLKTSLQSLAFRLWDEE
KKQFVTFRDMKQTSSHPSPDSTKKQKLRKNA

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71999459, Length=290, Percent_Identity=26.2068965517241, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17542730, Length=298, Percent_Identity=26.1744966442953, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 40679; Mature: 40548

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQTIAHKQKQLTKQVAAFAQPDTKNSLLQLLNTFIPFFGLWFLAYFSLNVSYLLTLGI
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVIAAGFLTRIFIIFHDCCHLSFFKQKRLNHILGFLTGVLTLFPYLQWQHSHSIHHATSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
NLDKRGTGDIWLLTVNEYKAAPLRTKIAYRLYRNPFIMFILGPIYVFLITNRFNKKGARR
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHH
KERVNTYLTNLAIAALAAVCCLIFGWQSFLLVQGPIFLISGSIGVWLFYVQHTFEDSYFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCC
ADENWSYVQAAVEGSSFYKLPKLLQWLTGNIGYHHVHHLSPKVPNYKLETAHEQHEPLKN
CCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCHHHCCHHHC
VPTITLKTSLQSLAFRLWDEEKKQFVTFRDMKQTSSHPSPDSTKKQKLRKNA
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
TEQTIAHKQKQLTKQVAAFAQPDTKNSLLQLLNTFIPFFGLWFLAYFSLNVSYLLTLGI
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVIAAGFLTRIFIIFHDCCHLSFFKQKRLNHILGFLTGVLTLFPYLQWQHSHSIHHATSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
NLDKRGTGDIWLLTVNEYKAAPLRTKIAYRLYRNPFIMFILGPIYVFLITNRFNKKGARR
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHH
KERVNTYLTNLAIAALAAVCCLIFGWQSFLLVQGPIFLISGSIGVWLFYVQHTFEDSYFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCC
ADENWSYVQAAVEGSSFYKLPKLLQWLTGNIGYHHVHHLSPKVPNYKLETAHEQHEPLKN
CCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCHHHCCHHHC
VPTITLKTSLQSLAFRLWDEEKKQFVTFRDMKQTSSHPSPDSTKKQKLRKNA
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]