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The map label for this gene is cdd [H]

Identifier: 52786456

GI number: 52786456

Start: 2618160

End: 2618570

Strand: Reverse

Name: cdd [H]

Synonym: BLi02721

Alternate gene names: 52786456

Gene position: 2618570-2618160 (Counterclockwise)

Preceding gene: 52786457

Following gene: 52786455

Centisome position: 62.01

GC content: 47.2

Gene sequence:

>411_bases
TTGACTAAACAAGAATTGATTGCAGAAGCTTTAAAAGCAAGGGAATTTGCATATGTTCCGTATTCGAAATTCAAAGTCGG
CGCTGCACTTTTAACCGAAGACGGCAAGGTGTACAAAGGCTGCAACATTGAAAATGCTGCATACAGCCTGTGCAACTGCG
CCGAGCGGACAGCGCTGTTCAAGGCTTATTCAGAAGGGGAAAAATCCTTTAAGATGCTTGCCGTTGCTGCGGATACGCCG
GGTCCGGTGTCGCCGTGCGGCGCCTGCAGACAGGTGATTTCCGAACTTTGTTCGCCAAACATGCCTGTCATCTTAACCAA
TCTGAATGGCCAAGTCAAAGAAATGACGGTTCAAGAATTACTGCCAGGAGCATTTTCATCGGAGGACTTACATGACACAG
GAAAGCTTTAA

Upstream 100 bases:

>100_bases
AAAATTTTACATTTGCGATTTGGGCGTGAAAAAGAAGCCATTTTTATGTAAAATAAAAGTGTTAGCGGTACCATCACTGC
TATAGGAAGGAATACACACA

Downstream 100 bases:

>100_bases
ATCAGGATTTGTCTCGATTATCGGACGACCAAACGTAGGAAAATCTACTTTTTTGAATCGCGTAATCGGCCAAAAAATCG
CCATCATGAGCGACAAACCG

Product: hypothetical protein

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MTKQELIAEALKAREFAYVPYSKFKVGAALLTEDGKVYKGCNIENAAYSLCNCAERTALFKAYSEGEKSFKMLAVAADTP
GPVSPCGACRQVISELCSPNMPVILTNLNGQVKEMTVQELLPGAFSSEDLHDTGKL

Sequences:

>Translated_136_residues
MTKQELIAEALKAREFAYVPYSKFKVGAALLTEDGKVYKGCNIENAAYSLCNCAERTALFKAYSEGEKSFKMLAVAADTP
GPVSPCGACRQVISELCSPNMPVILTNLNGQVKEMTVQELLPGAFSSEDLHDTGKL
>Mature_135_residues
TKQELIAEALKAREFAYVPYSKFKVGAALLTEDGKVYKGCNIENAAYSLCNCAERTALFKAYSEGEKSFKMLAVAADTPG
PVSPCGACRQVISELCSPNMPVILTNLNGQVKEMTVQELLPGAFSSEDLHDTGKL

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=131, Percent_Identity=54.1984732824427, Blast_Score=138, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17551074, Length=134, Percent_Identity=44.7761194029851, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17540514, Length=130, Percent_Identity=43.0769230769231, Blast_Score=105, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6323274, Length=125, Percent_Identity=43.2, Blast_Score=106, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24582741, Length=128, Percent_Identity=50.78125, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24582744, Length=103, Percent_Identity=52.4271844660194, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI19920920, Length=121, Percent_Identity=47.1074380165289, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14687; Mature: 14556

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQELIAEALKAREFAYVPYSKFKVGAALLTEDGKVYKGCNIENAAYSLCNCAERTALF
CCHHHHHHHHHHHHHEECCCHHHHHHHHHEECCCCCEECCCCCCHHHHHHHHHHHHHHHH
KAYSEGEKSFKMLAVAADTPGPVSPCGACRQVISELCSPNMPVILTNLNGQVKEMTVQEL
HHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHH
LPGAFSSEDLHDTGKL
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKQELIAEALKAREFAYVPYSKFKVGAALLTEDGKVYKGCNIENAAYSLCNCAERTALF
CHHHHHHHHHHHHHEECCCHHHHHHHHHEECCCCCEECCCCCCHHHHHHHHHHHHHHHH
KAYSEGEKSFKMLAVAADTPGPVSPCGACRQVISELCSPNMPVILTNLNGQVKEMTVQEL
HHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHH
LPGAFSSEDLHDTGKL
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2526291; 8969508; 9384377 [H]