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The map label for this gene is era [H]

Identifier: 52786455

GI number: 52786455

Start: 2617274

End: 2618179

Strand: Reverse

Name: era [H]

Synonym: BLi02720

Alternate gene names: 52786455

Gene position: 2618179-2617274 (Counterclockwise)

Preceding gene: 52786456

Following gene: 52786454

Centisome position: 62.0

GC content: 45.92

Gene sequence:

>906_bases
ATGACACAGGAAAGCTTTAAATCAGGATTTGTCTCGATTATCGGACGACCAAACGTAGGAAAATCTACTTTTTTGAATCG
CGTAATCGGCCAAAAAATCGCCATCATGAGCGACAAACCGCAAACAACAAGAAACAAAGTGCAAGGTGTGCTGACAACCG
ATACATCCCAGACGATTTTTATCGATACGCCCGGCATTCATAAACCGAAGCATAAATTGGGCGATTTTATGATGAAGGTG
GCGCACAACACTTTAAAGGAAGTCGACTTGATCTTGTTCATGATCAATGCGGAGGAAGGCTACGGAAAAGGCGACGAATT
TATCATTGAGCGATTAAAAGGAGTCAAGACGCCGGTATTTTTGATCGTCAACAAAATTGACCGGATTCATCCGGATGAGC
TTCTTGTGCTGATCGATGAGTACAGAACCAGGTATCCGTTTCAGGAAATCGTTCCGATCTCCGCCCTTGAGGGAAATAAT
ATCGATACGCTTTTAAAGCAAATTGAGGATTATTTGCCGGAAGGTCCGCAGTTTTACCCGAGTGACCAGGTGACCGATCA
TCCGGAGCGATTTATCATTTCTGAGCTGATTCGGGAAAAAGTGCTGCATCTGACAAGGGAAGAGATCCCTCACAGCATTG
CGGTCTCGATCGAGTCCATTCAAGAACGGGAAAACGGTTCTGTGTATGTGAGCGCGACCATCGTCGTCGAGCGAGATTCG
CAAAAAGGGATCGTCATCGGAAAAAGAGGCAGCCTGCTTAAAGAAATCGGCAAGCGGGCAAGAACCGATATCGAGGCGCT
GCTCGGGTCATCGGTGTTTTTAGAGCTGTGGGTTAAAGTGCAGAAAGACTGGCGCAACAAGATGTCTCAGCTTCGTGATT
TTGGATTTAGAGAAGACGAGTATTAA

Upstream 100 bases:

>100_bases
TCGCCAAACATGCCTGTCATCTTAACCAATCTGAATGGCCAAGTCAAAGAAATGACGGTTCAAGAATTACTGCCAGGAGC
ATTTTCATCGGAGGACTTAC

Downstream 100 bases:

>100_bases
CGGACAGAACTTGACCGCGGTTTAATCGTGACAATATCTCTCGAAATCAAAGATATATTAGAAAAAATTGTTTAACATGA
AATGGAGGATACAAGGTCAA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: Bex protein [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTQESFKSGFVSIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTRNKVQGVLTTDTSQTIFIDTPGIHKPKHKLGDFMMKV
AHNTLKEVDLILFMINAEEGYGKGDEFIIERLKGVKTPVFLIVNKIDRIHPDELLVLIDEYRTRYPFQEIVPISALEGNN
IDTLLKQIEDYLPEGPQFYPSDQVTDHPERFIISELIREKVLHLTREEIPHSIAVSIESIQERENGSVYVSATIVVERDS
QKGIVIGKRGSLLKEIGKRARTDIEALLGSSVFLELWVKVQKDWRNKMSQLRDFGFREDEY

Sequences:

>Translated_301_residues
MTQESFKSGFVSIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTRNKVQGVLTTDTSQTIFIDTPGIHKPKHKLGDFMMKV
AHNTLKEVDLILFMINAEEGYGKGDEFIIERLKGVKTPVFLIVNKIDRIHPDELLVLIDEYRTRYPFQEIVPISALEGNN
IDTLLKQIEDYLPEGPQFYPSDQVTDHPERFIISELIREKVLHLTREEIPHSIAVSIESIQERENGSVYVSATIVVERDS
QKGIVIGKRGSLLKEIGKRARTDIEALLGSSVFLELWVKVQKDWRNKMSQLRDFGFREDEY
>Mature_300_residues
TQESFKSGFVSIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTRNKVQGVLTTDTSQTIFIDTPGIHKPKHKLGDFMMKVA
HNTLKEVDLILFMINAEEGYGKGDEFIIERLKGVKTPVFLIVNKIDRIHPDELLVLIDEYRTRYPFQEIVPISALEGNNI
DTLLKQIEDYLPEGPQFYPSDQVTDHPERFIISELIREKVLHLTREEIPHSIAVSIESIQERENGSVYVSATIVVERDSQ
KGIVIGKRGSLLKEIGKRARTDIEALLGSSVFLELWVKVQKDWRNKMSQLRDFGFREDEY

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. Binds both GDP and GTP. Complements

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=322, Percent_Identity=23.6024844720497, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI1788919, Length=301, Percent_Identity=39.202657807309, Blast_Score=234, Evalue=5e-63,
Organism=Escherichia coli, GI87082120, Length=179, Percent_Identity=32.9608938547486, Blast_Score=99, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6323665, Length=200, Percent_Identity=26.5, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24646434, Length=313, Percent_Identity=26.1980830670927, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34411; Mature: 34280

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQESFKSGFVSIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTRNKVQGVLTTDTSQTIF
CCHHHHHCCCEEEECCCCCCHHHHHHHHHHHHEEEECCCCCHHHHHHCEEEEECCCCEEE
IDTPGIHKPKHKLGDFMMKVAHNTLKEVDLILFMINAEEGYGKGDEFIIERLKGVKTPVF
EECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCHHHHHHHHHCCCCHHH
LIVNKIDRIHPDELLVLIDEYRTRYPFQEIVPISALEGNNIDTLLKQIEDYLPEGPQFYP
HHHHHHHCCCCHHHEEEEHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
SDQVTDHPERFIISELIREKVLHLTREEIPHSIAVSIESIQERENGSVYVSATIVVERDS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEEEEECC
QKGIVIGKRGSLLKEIGKRARTDIEALLGSSVFLELWVKVQKDWRNKMSQLRDFGFREDE
CCCEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
Y
C
>Mature Secondary Structure 
TQESFKSGFVSIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTRNKVQGVLTTDTSQTIF
CHHHHHCCCEEEECCCCCCHHHHHHHHHHHHEEEECCCCCHHHHHHCEEEEECCCCEEE
IDTPGIHKPKHKLGDFMMKVAHNTLKEVDLILFMINAEEGYGKGDEFIIERLKGVKTPVF
EECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCHHHHHHHHHCCCCHHH
LIVNKIDRIHPDELLVLIDEYRTRYPFQEIVPISALEGNNIDTLLKQIEDYLPEGPQFYP
HHHHHHHCCCCHHHEEEEHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
SDQVTDHPERFIISELIREKVLHLTREEIPHSIAVSIESIQERENGSVYVSATIVVERDS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEEEEECC
QKGIVIGKRGSLLKEIGKRARTDIEALLGSSVFLELWVKVQKDWRNKMSQLRDFGFREDE
CCCEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
Y
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 2526291 [H]