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The map label for this gene is deoD

Identifier: 52786029

GI number: 52786029

Start: 2241618

End: 2242316

Strand: Reverse

Name: deoD

Synonym: BLi02285

Alternate gene names: 52786029

Gene position: 2242316-2241618 (Counterclockwise)

Preceding gene: 52786032

Following gene: 52786028

Centisome position: 53.1

GC content: 48.21

Gene sequence:

>699_bases
ATGAGCGTACATATTGGCGCAGAAAAAGGACAAATTGCAGAAACGGTGCTGCTTCCAGGAGACCCGCTGCGCGCAAAATA
TATCGCTGATACATATTTGGAAAACGTTGAATGTTATAACGAAGTACGGGGAATGTACGGGTTTACCGGCACTTATAAAG
GAAAGCGCGTTTCCGTTCAGGGGACGGGCATGGGTGTGCCGTCTATTTCAATTTATGTCAATGAACTGATCAGAAGCTAT
GATGTGAAAAACCTGATCCGCGTCGGATCGTGCGGTGCGATCAGAAAAGACGTCAATGTAAGAGATGTCATTCTTGCGAT
GACTTCATCAACTGATTCACAAATCAACAGAGTGGCATTCGGCTCGATCGACTTTGCGCCCTGCGCGGACTTCGGCCTGC
TAAAAGCTGCTTATGACGCTGCAAGTGAGCGGAACATCCCGGTTACGGCAGGGAATGTGTTTACGGCGGATCAATTCTAT
AACGACGACAGCCAAATTGAGAAGCTTGCCAAACACGGAGTGCTTGCGGTCGAGATGGAAACGACGGCGCTTTATACATT
GGCTGCGAAATTCGGCCGAAAAGCCCTCTCCATTTTAACGGTCAGCGATCACGTCATTACCGGCGAGGAAACAACGGCAG
AAGAAAGACAGACGACCTTTAATGATATGATTCTGCTGGCTCTGGATACTGCTTTGTAA

Upstream 100 bases:

>100_bases
CTTTATTTTCTTTTTCCGCGATGTTGGTTTATAATACATATGCGAGTGGATGTTGCAATCATCATCACCAATCAGCTTTA
AAAAGGCAGGAGGAATAATC

Downstream 100 bases:

>100_bases
AAGCATACATGCACTGAAAAAGGATGGATTCGAATGAACGGAAAGTACAAATACGTGACGATTGCTTCATTGCTGAGTGC
AGCGGTCCTGCTTGGCACAG

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSVHIGAEKGQIAETVLLPGDPLRAKYIADTYLENVECYNEVRGMYGFTGTYKGKRVSVQGTGMGVPSISIYVNELIRSY
DVKNLIRVGSCGAIRKDVNVRDVILAMTSSTDSQINRVAFGSIDFAPCADFGLLKAAYDAASERNIPVTAGNVFTADQFY
NDDSQIEKLAKHGVLAVEMETTALYTLAAKFGRKALSILTVSDHVITGEETTAEERQTTFNDMILLALDTAL

Sequences:

>Translated_232_residues
MSVHIGAEKGQIAETVLLPGDPLRAKYIADTYLENVECYNEVRGMYGFTGTYKGKRVSVQGTGMGVPSISIYVNELIRSY
DVKNLIRVGSCGAIRKDVNVRDVILAMTSSTDSQINRVAFGSIDFAPCADFGLLKAAYDAASERNIPVTAGNVFTADQFY
NDDSQIEKLAKHGVLAVEMETTALYTLAAKFGRKALSILTVSDHVITGEETTAEERQTTFNDMILLALDTAL
>Mature_231_residues
SVHIGAEKGQIAETVLLPGDPLRAKYIADTYLENVECYNEVRGMYGFTGTYKGKRVSVQGTGMGVPSISIYVNELIRSYD
VKNLIRVGSCGAIRKDVNVRDVILAMTSSTDSQINRVAFGSIDFAPCADFGLLKAAYDAASERNIPVTAGNVFTADQFYN
DDSQIEKLAKHGVLAVEMETTALYTLAAKFGRKALSILTVSDHVITGEETTAEERQTTFNDMILLALDTAL

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family

Homologues:

Organism=Escherichia coli, GI1790844, Length=230, Percent_Identity=55.6521739130435, Blast_Score=267, Evalue=6e-73,
Organism=Escherichia coli, GI1790265, Length=209, Percent_Identity=30.1435406698565, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOD_BACLD (Q65IE9)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_079446.1
- RefSeq:   YP_091858.1
- ProteinModelPortal:   Q65IE9
- SMR:   Q65IE9
- STRING:   Q65IE9
- EnsemblBacteria:   EBBACT00000057476
- EnsemblBacteria:   EBBACT00000058621
- GeneID:   3028666
- GeneID:   3098894
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02285
- KEGG:   bli:BL01437
- NMPDR:   fig|279010.5.peg.53
- eggNOG:   COG0813
- GeneTree:   EBGT00050000000479
- HOGENOM:   HBG617197
- OMA:   SFETHAF
- ProtClustDB:   PRK05819
- BioCyc:   BLIC279010-1:BLI02285-MONOMER
- BioCyc:   BLIC279010:BL01437-MONOMER
- HAMAP:   MF_01627
- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR00107

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =2.4.2.1

Molecular weight: Translated: 25209; Mature: 25078

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVHIGAEKGQIAETVLLPGDPLRAKYIADTYLENVECYNEVRGMYGFTGTYKGKRVSVQ
CEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
GTGMGVPSISIYVNELIRSYDVKNLIRVGSCGAIRKDVNVRDVILAMTSSTDSQINRVAF
ECCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCHHCCCCCEEEEEEEECCCCHHHHEEEE
GSIDFAPCADFGLLKAAYDAASERNIPVTAGNVFTADQFYNDDSQIEKLAKHGVLAVEME
CCCCCCCCCCHHHHHHHHHHCCCCCCCEECCCEEEHHHHCCCHHHHHHHHHCCEEEEEEH
TTALYTLAAKFGRKALSILTVSDHVITGEETTAEERQTTFNDMILLALDTAL
HHHHHHHHHHHCCCEEEEEEECCEEECCCCCCHHHHHHHHHHEEEEEEECCC
>Mature Secondary Structure 
SVHIGAEKGQIAETVLLPGDPLRAKYIADTYLENVECYNEVRGMYGFTGTYKGKRVSVQ
EEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
GTGMGVPSISIYVNELIRSYDVKNLIRVGSCGAIRKDVNVRDVILAMTSSTDSQINRVAF
ECCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCHHCCCCCEEEEEEEECCCCHHHHEEEE
GSIDFAPCADFGLLKAAYDAASERNIPVTAGNVFTADQFYNDDSQIEKLAKHGVLAVEME
CCCCCCCCCCHHHHHHHHHHCCCCCCCEECCCEEEHHHHCCCHHHHHHHHHCCEEEEEEH
TTALYTLAAKFGRKALSILTVSDHVITGEETTAEERQTTFNDMILLALDTAL
HHHHHHHHHHHCCCEEEEEEECCEEECCCCCCHHHHHHHHHHEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA